Clinical statistical analysis plan for the ACCURE trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicentre trial
This article presents the statistical analysis plan to evaluate the outcomes of the ACCURE trial.Design and methodsThe ACCURE trial was designed as a multicentre, randomised controlled trial. UC patients with a new diagnosis or a disease relapse within the past 12 months, treated with 5-ASA, corticosteroids, or immunomodulators until complete clinical and endoscopic remission (defined as total Mayo score < 3 with endoscopic subscore of 0 or 1), were counselled for inclusion. Also, patients previously treated with biologicals who had a washout period of at least 3 months were considered for inclusion. Patients we...
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials
Right Colectomy for Colon Cancer Database (RCC). Surgical Technique, Route of Access and Quality of the Specimen
Conditions: Right Sided Colon Cancer; Right Colectomy; Lymphadenectomy Interventions: Procedure: Surgical access Sponsors: Haukeland University Hospital; Intuitive Surgical Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Prevalence and Impact of Sarcopenia in Patients With Inflammatory Bowel Disease
Conditions: Inflammatory Bowel Diseases; Sarcopenia Interventions: Procedure: Colectomy Sponsors: Sahlgrenska University Hospital, Sweden; Ersta Hospital, Sweden Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials
Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer
Conditions: Colonic Neoplasms; Neoadjuvant Therapy; Immune Checkpoint Inhibitors Interventions: Drug: Anti-PD-1 monoclonal antibody; Drug: Oxaliplatin; Drug: Capecitabine 500 MG; Procedure: Colectomy Sponsors: First Affiliated Hospital of Guangxi Medical University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 9, 2023 Category: Research Source Type: clinical trials
Factors Affecting the Results of Treatment of Patients With Colorectal Cancer
Conditions: Colorectal Cancer; Colon Cancer; Rectal Cancer; Colorectal Adenocarcinoma; Colorectal Neoplasms Malignant; Rectal Adenocarcinoma Interventions: Procedure: Right hemicolectomy; Procedure: Left hemicolectomy; Procedure: Sigmoid colon resection; Procedure: Anterior resection of the rectum; Procedure: Low anterior resection of the rectum; Procedure: Abdominoperineal resection; Procedure: Total Colectomy Sponsors: Immanuel Kant Baltic Federal University; Center of Endourology " Endocenter " Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials
Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer
Condition: Colon Neoplasm Interventions: Drug: Oxaliplatin; Drug: Capecitabine; Drug: Anti-PD-L1 Monoclonal Antibody; Drug: Clostridium butyricum; Procedure: Colectomy Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 22, 2023 Category: Research Source Type: clinical trials
