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Notes from the Field: Clostridium perfringens Gastroenteritis Outbreak Associated with a Catered Lunch — North Carolina, November 2015
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - November 23, 2016 Category: American Health Source Type: news

Trusting Your Gut: Diagnosis and Management of Clostridium septicum Infections
Clostridium septicum is a Gram-positive anaerobic bacillus that causes serious, life-threatening infections, including aggressive septicemia and myonecrosis. Clostridial myonecrosis can be broadly classified into two defined clinical presentations: traumatic and spontaneous. Clostridium perfringens is the most common cause of traumatic myonecrosis, while C. septicum is the most common etiological agent of spontaneous myonecrosis. Although rarely clinically encountered, C. septicum infections are often fatal. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 19, 2016 Category: Microbiology Authors: Michael J.G. Mallozzi, Andrew E. Clark Source Type: news

Stopping foodborne illness — faster testing, vigilance at home
The steady stream of reports about foodborne illness is making me think twice about what’s on my dinner plate. This year alone, we’ve seen dozens of food recalls, including one involving frozen tuna that was linked to 62 cases of Salmonella infection, and another that implicated ice cream in 10 cases of Listeria infection — and three deaths. Foodborne illness sickens 48 million people annually, sending 128,000 to the hospital and killing 3,000. You can get a foodborne illness from red meat, poultry, fish, eggs, dairy foods, and even fruits and vegetables. Bacteria in the Salmonella family are culprit No. ...
Source: New Harvard Health Information - July 30, 2015 Category: Consumer Health News Authors: Heidi Godman Tags: Safety food safety foodborne illness Source Type: news

Oncoleaking: Use of the Pore-Forming Clostridium perfringens Enterotoxin (CPE) for Suicide Gene Therapy
Suicide gene therapy has been shown to be very efficient in tumor eradication. Numerous suicide genes were tested in vitro and in vivo demonstrating their therapeutic potential in clinical trials. Apart from this, still growing efforts are made to generate more targeted and more effective suicide gene systems for cancer gene therapy. In this regard bacterial toxins are an alternative, which add to the broad spectrum of different suicide strategies. In this context, the claudin-targeted bacterial Clostridium perfringens enterotoxin (CPE) is an attractive new type of suicide oncoleaking gene, which as pore-forming protein ex...
Source: Springer protocols feed by Cancer Research - June 26, 2015 Category: Cancer & Oncology Source Type: news

Gate for bacterial toxins found
(University of Freiburg) Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell. The TpeL toxin is formed by C. perfringens, a pathogen that causes gas gangrene and food poisoning. It is very similar to the toxins of many other hospital germs of the genus Clostridium. Aktories is member of the BIOSS Centre for Biological Signalling Studies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 16, 2014 Category: Biology Source Type: news

MS could be linked to food poisoning bacteria
Research in mice and small studies in humans suggest that a toxin produced by the bacterium C. perfringens could be a trigger for MS. (Source: Multiple Sclerosis Trust)
Source: Multiple Sclerosis Trust - January 29, 2014 Category: Neurology Source Type: news

Bacterial Toxin May Trigger Multiple Sclerosis Bacterial Toxin May Trigger Multiple Sclerosis
Researchers have identified a toxin produced by Clostridium perfringens type B as a possible trigger for MS, raising the potential for some novel therapeutic strategies. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 25, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Soil-based bacteria discovered in humans 'may trigger MS'
Scientists have discovered a soil-based bacteria in humans for the first time, and they believe it may be a trigger of multiple sclerosis. This is according to a study published in the journal PLOS ONE. Researchers from Weill Cornell Medical College and Rockefeller University discovered the bacterium Clostridium C. perfringens type B in a 21-year-old patient suffering from multiple sclerosis (MS). The researchers say although their study is small, their findings are so "intriguing" that it has caused them to start work on new treatments for the debilitating disorder... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 21, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Toxin from bacterium
American researchers suggest that MS may be triggered by toxins emitted by the lostridium C. perfringens type B bacterium in the gut. Red Orbit Medical News Today Latest MS research updates (Source: Multiple Sclerosis Trust)
Source: Multiple Sclerosis Trust - October 16, 2013 Category: Neurology Source Type: news