Serious Infection With STEMI PCI May Hurt Angiographic Results Serious Infection With STEMI PCI May Hurt Angiographic Results
More potent antiplatelets"such as ticagrelor instead of clopidogrel in patients with ACS and serious infections could be of benefit," the authors suggest.Heartwire from Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 26, 2016 Category: Consumer Health News Tags: Cardiology News Source Type: news

Plavix Smoker's Paradox Debunked? (CME/CE)
(MedPage Today) -- Hemoglobin confounds platelet level readings, study suggests (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - August 16, 2016 Category: Geriatrics Source Type: news

Real-world data confirm benefits of ticagrelor in ACS
A prospective study of more than 45,000 patients with acute coronary syndromes has shown that the risk of death or readmission with myocardial infarction or stroke is 15% lower with ticagrelor than with clopidogrel. (Source: MedWire News)
Source: MedWire News - July 26, 2016 Category: Consumer Health News Tags: Acute coronary syndromes Source Type: news

Plavix vs Effient: No Consistent Winner In Real-World Data (CME/CE)
(MedPage Today) -- Separate analyses yield conflicting results on the same observational data (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - July 20, 2016 Category: Geriatrics Source Type: news

Genetic Testing to Guide Clopidogrel Treatment in Stroke/TIA?Genetic Testing to Guide Clopidogrel Treatment in Stroke/TIA?
A substudy of the CHANCE trial shows clopidogrel is of no additional benefit over aspirin alone for patients with TIA or minor stroke who carry the clopidogrel loss-of-function genes. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - July 5, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

As preventive, H2RA poses risks for patients on clopidogrel after bleeding ulcer
SAN DIEGO – New research suggests histamine-2 receptor antagonists aren’t a viable alternative to proton pump inhibitors to prevent recurrence of bleeding peptic ulcers in clopidogrel users. U.S.... (Source: Family Practice News)
Source: Family Practice News - June 27, 2016 Category: Primary Care Source Type: news

Gene Variant Reduces Plavix Response After Minor Stroke (CME/CE)
(MedPage Today) -- GYP2C19 genotyping may identify nonresponsive patients (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 27, 2016 Category: Cardiology Source Type: news

Gene Variant Reduces Clopidogrel Response After Minor Stroke (CME/CE)
(MedPage Today) -- CYP2C19 genotyping may identify nonresponsive patients (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - June 26, 2016 Category: Neurology Source Type: news

CYP2C19 gene variants undermine clopidogrel stroke prevention
The first look at CYP2C19 mutations in the context of a randomised controlled trial has confirmed suspicions that they affect the efficacy of clopidogrel in patients with acute stroke. (Source: MedWire News)
Source: MedWire News - June 24, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Clopidogrel and Hip Fractures, Is It Safe?Clopidogrel and Hip Fractures, Is It Safe?
The perioperative management of patients on anticoagulant or antiplatelet therapy can be challenging, and orthopedic surgeons must weigh the risks and benefits. Find out what there is to know. BMC Musculoskeletal Disorders (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 9, 2016 Category: Consumer Health News Tags: Orthopaedics Journal Article Source Type: news

Better than Aspirin for Your Heart
If you’ve been diagnosed with heart disease, the chances are you’ve been told to take low-dose aspirin every day as a preventative measure against heart attack and stroke. It’s most commonly prescribed for patients with congestive heart failure. This is the inability of your heart to pump as much blood as your body needs. And this is a big worry to me, because there is very little evidence that aspirin helps. In fact, regular use of aspirin — even baby aspirin — can do you more harm than good. Common Aspirin Beliefs The idea is that aspirin thins the blood, making it easier to pump.  It is also s...
Source: Al Sears, MD Natural Remedies - April 1, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health Source Type: news

Brilinta preferred over clopidogrel in updated American College of Cardiology and American Heart Association guideline in acute coronary syndrome
AstraZeneca today confirmed that the American College of Cardiology (ACC) and American Heart Association (AHA) have released a treatment guideline on the duration of dual antiplatelet therapy (DAPT). Brilinta (ticagrelor) is now preferred over clopidogrel for the management of patients with acute coronary syndrome (ACS) who have received a coronary stent and in non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) patients treated with medical therapy alone (Class IIa LoE: B-R). (Source: World Pharma News)
Source: World Pharma News - March 31, 2016 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

FDA Drug Safety Communication: Reduced effectiveness of Plavix (clopidogrel) in patients who are poor metabolizers of the drug
[03-12-2010] The U.S. Food and Drug Administration (FDA) has added a Boxed Warning to the label for Plavix, the anti-blood clotting medication. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 24, 2016 Category: Drugs & Pharmacology Source Type: news

FDA reminder to avoid concomitant use of Plavix (clopidogrel) and omeprazole
The U.S. Food and Drug Administration (FDA) is reminding the public that it continues to warn against the concomitant use of Plavix (clopidogrel) and omeprazole because the co-administration can result in significant reductions in clopidogrel's active metabolite levels and antiplatelet activity. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 11, 2016 Category: Drugs & Pharmacology Source Type: news

ISC: Newer Anticoagulants Riskier for Afib Patients Needing Antiplatelet Tx? (CME/CE)
(MedPage Today) -- More bleeds versus warfarin in combination with clopidogrel post-PCI (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 19, 2016 Category: Cardiology Source Type: news