Silver Diamine Fluoride Topical Solution Halts Tooth Decay in Children
March 8, 2024 -- A topical liquid, silver diamine fluoride (SDF), can stop tooth decay in young children, according to a large clinical trial funded by the National Institutes of Health. The preliminary results, published in Pediatric Dentistry,... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 8, 2024 Category: Pharmaceuticals Source Type: clinical trials

NodThera ’s NLRP3 Inhibitor NT-0796 Reverses Neuroinflammation in Parkinson’s Disease Phase Ib/IIa Trial
BOSTON, MA, March 7, 2024– NodThera, a leading clinical-stage biotech developing brain-penetrant NLRP3 inflammasome inhibitors to treat chronic inflammatory diseases, today announces positive data from its Phase Ib/IIa study... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 7, 2024 Category: Pharmaceuticals Source Type: clinical trials

New clinical study published demonstrates superiority of AI-algorithm guided melanoma diagnosis
STOCKHOLM, March 6, 2024. Results from a prospective, multicentre, clinical trial published today in the peer-reviewed British Journal of Dermatology showed that AI helps significantly improve melanoma detection rates. The trial, conducted in 37... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 7, 2024 Category: Pharmaceuticals Source Type: clinical trials

MindMed Receives FDA Breakthrough Therapy Designation and Announces Positive 12-Week Durability Data From Phase 2B Study of MM120 for Generalized Anxiety Disorder
NEW YORK--(BUSINESS WIRE) Mar 07, 2024  -- Mind Medicine (MindMed) Inc. (NASDAQ: MNMD), (Cboe Canada MMED), (the“Company” or“MindMed”), a clinical stage biopharmaceutical company developing novel product candidates to... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 7, 2024 Category: Pharmaceuticals Source Type: clinical trials

BlueRock Therapeutics Phase I Clinical Trial for Bemdaneprocel for Parkinson ’s Disease Continues to Show Positive Trends at 18 Months
Berlin, Germany and Cambridge, MA USA, March 6, 2024– Bayer AG and BlueRock Therapeutics LP, a clinical stage cell therapy company and wholly owned independently operated subsidiary of Bayer AG, announced today details of 18-month data from... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 6, 2024 Category: Pharmaceuticals Source Type: clinical trials

Gilead and Merck Announce Phase 2 Data Showing an Investigational Oral Once-Weekly Combination Regimen of Islatravir and Lenacapavir Maintained Viral Suppression at Week 24
FOSTER CITY, Calif.,& RAHWAY, N.J.--(BUSINESS WIRE) March 06, 2024 -- Gilead Sciences, Inc. (Nasdaq: GILD) and Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced results from the Phase 2 clinical study... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 6, 2024 Category: Pharmaceuticals Source Type: clinical trials

Long-Acting HIV Treatment Benefits Adults with Barriers to Daily Pill Taking and Adolescents with Suppressed HIV
March 6, 2024 -- Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 6, 2024 Category: Pharmaceuticals Source Type: clinical trials

Dapivirine Vaginal Ring and Oral Pre-Exposure Prophylaxis Found Safe for HIV Prevention Throughout Pregnancy
March 5, 2024 -- The monthly dapivirine vaginal ring and daily oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine were each found to be safe for HIV prevention among cisgender women who started... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 5, 2024 Category: Pharmaceuticals Source Type: clinical trials

Semaglutide Reduces Severity of Common Liver Disease in People with HIV
March 5, 2024 -- A weekly injection of semaglutide was safe and reduced the amount of fat in the liver by 31% in people with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD), according to a presentation today at the 2024... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 5, 2024 Category: Pharmaceuticals Source Type: clinical trials

Verastem Oncology Receives Orphan Drug Designation from FDA for Avutometinib Alone or in Combination With Defactinib in Recurrent Low-Grade Serous Ovarian Cancer
BOSTON--(BUSINESS WIRE)--Mar. 5, 2024-- Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients, today announced that the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 5, 2024 Category: Pharmaceuticals Source Type: clinical trials

NRx Pharmaceuticals Announces Last Patient, Last Visit in its Phase 2b/3 Trial of NRX-101 in Suicidal Treatment Resistant Bipolar Depression
RADNOR, Pa., March 4, 2024. NRx Pharmaceuticals, Inc. ( " NRx Pharmaceuticals " , the " Company " ), a clinical-stage biopharmaceutical company, today announced that the 74th and last evaluable patient has completed their day 42 visit in its Phase 2b/3... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 4, 2024 Category: Pharmaceuticals Source Type: clinical trials

SciSparc Delivers Treatment for Autism Spectrum Disorder Clinical Trial Enabling Commencement of Dosing
TEL AVIV, Israel, Feb. 29, 2024. SciSparc Ltd. ( " Company " or " SciSparc " ), a specialty clinical-stage pharmaceutical company focusing on the development of therapies to treat disorders and rare diseases of the central nervous system, today announced... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 29, 2024 Category: Pharmaceuticals Source Type: clinical trials

Ironwood Pharmaceuticals Announces Positive Topline Results from Global Phase III Trial of Once-Weekly Apraglutide in Adults with Short Bowel Syndrome with Intestinal Failure (SBS-IF)
BOSTON--(BUSINESS WIRE) February 29, 2024 -- Ironwood Pharmaceuticals, Inc. (Nasdaq: IRWD), a GI-focused healthcare company, today announced positive topline results from its pivotal Phase III STARS trial, which evaluated the efficacy and safety of... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 29, 2024 Category: Pharmaceuticals Source Type: clinical trials

Palatin Announces Results of PL9643 MELODY-1 Pivotal Phase 3 Clinical Trial in Patients with Dry Eye Disease (DED)
CRANBURY, N.J., Feb. 28, 2024 -- Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of the melanocortin receptor system, today announced... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 28, 2024 Category: Pharmaceuticals Source Type: clinical trials

Lutris Pharma Receives FDA Orphan Drug Designation for LUT014 for the Treatment of EGFRI-Induced Acneiform Rash
Feb. 28, 2024 -- Lutris Pharma, a clinical stage biopharmaceutical company focused on improving anti-cancer therapies by reducing dose limiting side effects, today announced that the U.S. Food and Drug Administration ' s... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 28, 2024 Category: Pharmaceuticals Source Type: clinical trials