Effects of second-generation H1-antihistamine drugs on angiogenesis in < em > in vivo < /em > chick chorioallantoic membrane model
CONCLUSIONS: Rupatadine showed anti-angiogenic effects in the chick CAM model, compared with desloratadine and cetirizine. The anti-angiogenic effect of rupatadine could be due to its platelet-activating factor (PAF) receptor inhibition. Thus, rupatadine could be a treatment agent in pathological processes in which angiogenesis is responsible. Further studies with larger series are needed to clarify this potential.PMID:36469932 | DOI:10.1080/15569527.2022.2152040 (Source: Cutaneous and Ocular Toxicology)
Source: Cutaneous and Ocular Toxicology - December 5, 2022 Category: Toxicology Authors: Nilay Duman Re şat Duman Ayhan Vurmaz Source Type: research
Antimicrobial and antibiofilm activities of desloratadine against multidrug-resistant Acinetobacter baumannii
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - November 10, 2022 Category: Microbiology Authors: Junio Eduvirgem Luana Rossato Andressa LF Melo Anna CM Valiente Luiz F Pla ça Heberton Wender Marcia SM Vaz Suzana M Ribeiro Simone Simionatto Source Type: research
Desloratadine efficacy in relation to GSTM1 and GSTT1 polymorphic genes in chronic spontaneous urticaria
Conclusion: These results suggest the impact of GSTM1 and GSTT1 on CSU susceptibility and desloratadine efficacy in Tunisian patients. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - September 23, 2022 Category: Dermatology Authors: Amal Maouia Nadia Leban Monia Youssef Ahmed Noureddine Helal Asma Kassab Source Type: research
[ASAP] Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery
Molecular PharmaceuticsDOI: 10.1021/acs.molpharmaceut.2c00292 (Source: Molecular Pharmaceutics)
Source: Molecular Pharmaceutics - June 27, 2022 Category: Drugs & Pharmacology Authors: Daniel Porat, Oleg Dukhno, Ella Vainer, Sandra Cvijic ́, and Arik Dahan Source Type: research
Contact dermatitis due to personal protective equipment use and hygiene practices during the COVID-19 pandemic: A systematic review of case reports
CONCLUSION: This study finds pertinent links between PPE use and contact dermatitis during the COVID-19 pandemic. While many cases are bound to go underreported in literature, well-designed, large-scale studies in the future may help promote these associations in a more comprehensive manner.PMID:35039780 | PMC:PMC8755461 | DOI:10.1016/j.amsu.2022.103254 (Source: Hand Surgery)
Source: Hand Surgery - January 18, 2022 Category: Surgery Authors: Zouina Sarfraz Azza Sarfraz Muzna Sarfraz Miguel Felix Jonathan A Bernstein Luz Fonacier Ivan Cherrez-Ojeda Source Type: research
Contact dermatitis due to personal protective equipment use and hygiene practices during the COVID-19 pandemic: A systematic review of case reports
CONCLUSION: This study finds pertinent links between PPE use and contact dermatitis during the COVID-19 pandemic. While many cases are bound to go underreported in literature, well-designed, large-scale studies in the future may help promote these associations in a more comprehensive manner.PMID:35039780 | PMC:PMC8755461 | DOI:10.1016/j.amsu.2022.103254 (Source: Annals of Medicine)
Source: Annals of Medicine - January 18, 2022 Category: Internal Medicine Authors: Zouina Sarfraz Azza Sarfraz Muzna Sarfraz Miguel Felix Jonathan A Bernstein Luz Fonacier Ivan Cherrez-Ojeda Source Type: research
Contact dermatitis due to personal protective equipment use and hygiene practices during the COVID-19 pandemic: A systematic review of case reports
CONCLUSION: This study finds pertinent links between PPE use and contact dermatitis during the COVID-19 pandemic. While many cases are bound to go underreported in literature, well-designed, large-scale studies in the future may help promote these associations in a more comprehensive manner.PMID:35039780 | PMC:PMC8755461 | DOI:10.1016/j.amsu.2022.103254 (Source: Hand Surgery)
Source: Hand Surgery - January 18, 2022 Category: Surgery Authors: Zouina Sarfraz Azza Sarfraz Muzna Sarfraz Miguel Felix Jonathan A Bernstein Luz Fonacier Ivan Cherrez-Ojeda Source Type: research
Desloratadine Exposure and Incidence of Seizure: A Nordic Post-authorization Safety Study Using a New-User Cohort Study Design, 2001 –2015
ConclusionThis study found an increased incidence rate of seizure during DL exposed periods as compared to unexposed periods among individuals younger than 20 years. No difference in incidence rate of seizure was observed in adults between DL exposed and unexposed. (Source: Drug Safety)
Source: Drug Safety - October 5, 2021 Category: Drugs & Pharmacology Source Type: research
Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials
CONCLUSION: The combination of desloratadine and compound glycyrrhizin is a promising treatment for CU and is associated with decreased serum IgE level and improved proportions of CD4+ T and CD8+ T cells.PMID:34517748 | DOI:10.1080/13880209.2021.1973039 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 14, 2021 Category: Drugs & Pharmacology Authors: Yulong Wen Yidan Tang Miaoyue Li Yu Lai Source Type: research
Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug
Conclusion: The developmental pharmacogenetics of CYP2D6 in Chinese children was evaluated using loratadine as a substrate drug. This study emphasizes the importance of evaluating the developmental pharmacogenetics in populations of different ancestries. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - July 6, 2021 Category: Drugs & Pharmacology Source Type: research
