Common Antidepressants Linked to Higher Fracture Odds in Menopausal Women
Drugs like Celexa, Prozac could undermine bone, research suggests Source: HealthDay Related MedlinePlus Pages: Antidepressants, Fractures, Menopause (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 26, 2015 Category: Consumer Health News Source Type: news

Is It Bedtime for Benzos?
“Bernard also laughed; after two grams of soma the joke seemed, for some reason, good. Laughed and then, almost immediately, dropped off to sleep.” — Aldous Huxley, Brave New World It’s been a tough few years for benzodiazepines, the pharmaceutical industry’s top-selling family of prescription drugs. Tough in every way, that is, except sales: Xanax remains the world’s most popular pill, and U.S. prescriptions for it and other benzos grow by 12 percent every year. It’s their reputation, long enjoyed, as harmless and effective medicines that’s taking a flurry of hits — so...
Source: Science - The Huffington Post - June 25, 2015 Category: Science Source Type: news

A Troubling Potential Link Between Sleep Aids And Mental Illness
In today's "always on," high-stress world, it has become commonplace to turn to over-the-counter sleep aids for a little help with drifting off into dreamland at night. However, that habit, if made a consistent one, could lead to potentially serious damage when it comes to ones mental health. A new study zeroing in on anticholinergic drugs -- a category that includes common non-prescription sleeping aids and antihistamines like Benadryl -- found that the long-term use of such medications in higher doses can lead to an increased risk of developing dementia, including Alzheimer's disease, in the future. It's the f...
Source: Science - The Huffington Post - April 7, 2015 Category: Science Source Type: news

Medication and Anxiety
Medication can be an effective approach for managing various types of anxiety such as panic, hyperarousal, and constant worry. However, contrary to popular belief and subtle messages from pharmaceutical companies, medication is far from a cure. In fact, when it comes to “cures” for most psychiatric conditions, the data tends to support psychotherapy. For example, post-traumatic stress disorder (PTSD) responds very well to psychotherapy, whereas the positive effects of medication are somewhat limited. The same is true for panic disorder. Although certain types of medication are very good at relieving panic sympt...
Source: Psych Central - March 11, 2015 Category: Psychiatry Authors: Bret Moore, PsyD Tags: Anti-anxiety Antidepressants Benzodiazepines Disorders General Medications Panic Disorder anti-anxiety medications Drug Dependency Fear Hyperarousal Sedatives Selective Serotonin Reuptake Inhibitor snri Ssri Substance Abuse Source Type: news

Stimulant May Speed Antidepressant Response Time in ElderlyStimulant May Speed Antidepressant Response Time in Elderly
Methylphenidate combined with the antidepressant citalopram significantly reduced time to depression remission in elderly patients. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 4, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

Excellent review of lipid rescue therapy
3.5 out of 5 stars Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. Cao D et al. J Emerg Med 2014 Dec 19 [Epub ahead of print] Abstract This excellent comprehensive review of lipid rescue therapy (LRT) is vitiated only by the unavoidable fact that available clinical evidence  is so inconclusive. As the authors point out, published literature consists mostly of case reports and small case series. The vast majority of these reported cases have good outcomes and reflect positive effects from ILE, but the evidence is marred by multiple confounding variables (such ...
Source: The Poison Review - February 26, 2015 Category: Toxicology Authors: Leon Tags: Medical intralipid lipid emulsion lipid rescue therapy lipid sink Review Source Type: news

Study suggests combination drug therapy to treat depression in the elderly
FINDINGS This new study by researchers at UCLA found that the combination of Ritalin (methylphenidate) and Celexa (citalopram) can accelerate and improve the overall antidepressant effects of the medications in the elderly. Most patients who responded to the combination achieved remission in the first month. The researchers had also hoped to find that the combination would work more quickly and be tolerated better by this elderly population than either drug alone. They found that the combination was working faster, but the side effects and cognitive benefits did not differ between the groups. IMPACT Geriatric depression is...
Source: UCLA Newsroom: Health Sciences - February 24, 2015 Category: Universities & Medical Training Source Type: news

Gut Feelings: Diet, Depression and Bacteria
In another setback for the notion that depression is all in your head, recent research suggests it may be a gut reaction. Literally. Brain has always bested bowel in the body battles for executive organ status. However, the gastrointestinal tract is moving up in the world and recently was labeled the second brain. Laboratories all over the world have been mapping a bi-directional information highway between these two organs called the gut-brain axis. This connection has revealed the gut's influence on a wide range of things, from satiety and obesity to mood and anxiety. Even how we respond to stress is no longer the sole...
Source: Healthy Living - The Huffington Post - February 17, 2015 Category: Consumer Health News Source Type: news

Common anticholinergic drugs like Benadryl linked to increased dementia risk
This study is another reminder to periodically evaluate the all drugs you’re taking. Look at each one to determine if it’s really helping,” says Dr. Sarah Berry, a geriatrician and assistant professor of medicine at Harvard Medical School. “I’ve seen people who have been on anticholinergic medications for bladder control for years and they are completely incontinent. These drugs obviously aren’t helping.” Many drugs have a stronger effect on older people than younger people. With age, the kidneys and liver clear drugs more slowly, so drug levels in the blood remain higher for a lon...
Source: New Harvard Health Information - January 29, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Alzheimer's Disease Drugs and Supplements Mental Health anticholinergic drugs Source Type: news

Pain Research Pubs
2014 Is Already a Record YearI am pleased with the acceleration of publications by Pain Researchers using our Pain Research Markers and Gene Expression Analysis Tools.Here's a sampling of the most recent: Transfection Regent Publications: Lili Hou, Yanfeng Zhang, Yong Yang, Kai Xiang, Qindong Tan, Qulian Guo. Intrathecal siRNA Against GPNMB Attenuates Nociception in a Rat Model of Neuropathic Pain. Journal of Molecular Neuroscience. July 2014...Ten micrograms of siRNA1- GPNMB dissolved in 30 μl i-Fect transfection reagent (Neuromics, Edina, MN, USA) was administered intrathecally once daily for 7 days, starting from 1 d...
Source: Neuromics - August 7, 2014 Category: Neuroscience Tags: gene expression analysis Gene Silencing GPNMB Gene i-Fect pro-Dynorhin Antibody siRNA delivery in-vivo TRPV1 antibodies Source Type: news

Forest Pharmaceuticals failed to warn of fatal birth defects from antidepressant use, lawsuit claims
(NaturalNews) Forest Pharmaceuticals is under fire for causing fatal birth defects with its antidepressant drugs Lexapro [S-(+)-1-[3-(dimethyl-amino) propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile oxalate] and Celexa [-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran... (Source: NaturalNews.com)
Source: NaturalNews.com - July 28, 2014 Category: Consumer Health News Source Type: news

What Medications Should Be Avoided with Long QT Syndrome?
Discussion Mycoplasma pneumoniae is a frequent cause of pharyngitis, pneumonia and acute bronchitis, but acute otitis media is uncommon. Symptoms are usually self-limited and variable and include cough (non-productive usually but later can be productive), fever, fatigue and occasionally headache. Coryza is rare. Cough can continue for 3 to 4 weeks and can be accompanied by wheezing. Radiographic changes include diffuse infiltrates or focal abnormalities but are variable. Long QT syndrome (LQTS) is a group of disorders that have a prolonged QT interval and a polymorphic ventricular tachycardia. Torsade de pointes (“t...
Source: PediatricEducation.org - July 14, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Citalopram increases the differentiation efficacy of BMSCs into neuronal-like cells
(Neural Regeneration Research) There is evidence that selective serotonin reuptake inhibitor antidepressants can promote neuronal cell proliferation and enhance neuroplasticity both in vitro and in vivo. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2014 Category: Global & Universal Source Type: news

Should You Take Celexa for Depression?
Celexa - generic citalopram - is a medication used to treat depression. Celexa is a member of the SSRI drug family. These drugs work by making more serotonin available between nerve cells, which has been shown to ease depression. Article covers the benefits of Celexa, precautions and warnings, and information regarding pregnancy and Celexa. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - June 24, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

What Are the Potential Side Effects of...
List of Citalopram side effects. Citalopram (brand name Celexa) is an antidepressant sometimes prescribed in the treatment of bipolar disorder and other mood disorders. You need to know about potential side effects if you are taking or considering taking this medication. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - June 10, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Featured in NEJM Journal Watch: Might SSRIs Reduce the Risk for Alzheimer Disease? (FREE)
By the NEJM Journal Watch Editors Citalopram … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 27, 2014 Category: Primary Care Source Type: news

Happy pill 'wards of Alzheimer's': Widely used anti-depressant can help reduce formation of plaque on the brain
Scientists say citalopram can significantly reduce the formation of plaques in the brain, which could go some way to warding off the disease. (Source: the Mail online | Health)
Source: the Mail online | Health - May 15, 2014 Category: Consumer Health News Source Type: news

A commonly prescribed antidepressant may slow Alzheimer's
Alex CukanST. LOUIS, May 14 (UPI) -- The commonly prescribed antidepressant Celexa, or citalopram, may reduce production of brain plaques linked to Alzheimer's disease. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 15, 2014 Category: Consumer Health News Source Type: news

Could Certain Antidepressants Slow Alzheimer's?
Early study suggests Celexa, and other drugs in its class, might help, but many questions remain (Source: WebMD Health)
Source: WebMD Health - May 14, 2014 Category: Consumer Health News Source Type: news

Preventing Alzheimer's disease — with an antidepressant
Citalopram, an antidepressant better known by its commercial name Celexa, has a remarkable side effect, a new study has found: In both mice bred to develop Alzheimer's disease and in healthy human volunteers, the selective serotonin reuptake inhibitor, or SSRI, drives down the production of a... (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - May 14, 2014 Category: Science Source Type: news

Could Certain Antidepressants Slow Alzheimer'S?
Early study suggests Celexa, and other drugs in its class, might help, but many questions remain Source: HealthDay Related MedlinePlus Pages: Alzheimer's Disease, Antidepressants (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 14, 2014 Category: Consumer Health News Source Type: news

Anti-depressant prevents amyloid build up in the brains of mice and men
A study published in Science Translational Medicine from the University of Pennsylvania, has discovered that the anti-depressant drug Citalopram reduces the production of amyloid beta. (Source: Alzheimers Society)
Source: Alzheimers Society - May 14, 2014 Category: Geriatrics Source Type: news

Learn About Lexapro
Lexapro is one of the SSRI antidepressants and was created from Celexa (citalopram). The generic name of Lexapro is escitalopram. There are several warnings about Lexapro, especially about mixing it with other drugs and over-the-counter supplements, and discontinuing Lexapro treatment too quickly can cause a variety of unpleasant side effects. This Lexapro Drug Profile will give you in-depth information about this antidepressant. Photo: Joe Raedle/Getty Images News/Getty ImagesLearn more or join the conversation! NEWSLETTER | FORUMS | BIO | FACEBOOK | TWITTER (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - April 22, 2014 Category: Psychiatry Source Type: news

Molecular Psychiatry online: March 11, 2014
Preliminary evidence that early reduction in p11 levels in natural killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram P. Svenningsson, L. Berg, D. Matthews, D. F. Ionescu, E. M. … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 11, 2014 Category: Biomedical Science Authors: pubaff Tags: Research Update Source Type: news

Citalopram for Agitation in Alzheimer Disease Citalopram for Agitation in Alzheimer Disease
Citalopram produced a clinically relevant reduction in agitation in patients with Alzheimer disease with modest adverse effects. Medscape Neurology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 5, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery Viewpoint Source Type: news

Study: Should Antidepressant Celexa Be Used for Agitation in Dementia?
Agitation- including restlessness, wandering, combativeness and calling out- is a common challenge in Alzheimer's disease and other kinds of dementia. So, what to do about it? A study was recently published in the Journal of the American Medical Association, outlining a trial of the antidepressant medication citalopram (brand names: Celexa and Cipramil) to treat agitation in dementia. Here are the results, which are both positive and negative: The participants who received citalopram showed a significant decrease in their agitation. Caregiver distress, which is increased by agitation, also significantly improved. How...
Source: About Alzheimers Disease - March 2, 2014 Category: Consumer Health News Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include the best treatment for ear infections in kids with tubes, first-line treatment for atrial fibrillation, how to manage asymptomatic AVMs, and citalopram for agitation in Alzheimer's disease. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 21, 2014 Category: Psychiatry Source Type: news

Anti-depressant Citalopram could help ease Alzheimer's symptoms
The drug Citalopram - sold under the brand names Celexa and Cipramil - significantly relieved agitation in a group of Alzheimer's patients. (Source: the Mail online | Health)
Source: the Mail online | Health - February 19, 2014 Category: Consumer Health News Source Type: news

Antidepressant Celexa May Help Ease Alzheimer's-Linked Agitation
Title: Antidepressant Celexa May Help Ease Alzheimer's-Linked AgitationCategory: Health NewsCreated: 2/18/2014 4:36:00 PMLast Editorial Review: 2/19/2014 12:00:00 AM (Source: MedicineNet Alzheimer)
Source: MedicineNet Alzheimer - February 19, 2014 Category: Geriatrics Source Type: news

Citalopram Associated with Reduced Agitation in Alzheimer's, But at What Cost? (FREE)
By Kelly Young The selective serotonin reuptake inhibitor citalopram is associated with reduced agitation in people with Alzheimer disease — but with significant side effects — according to a JAMA study.Nearly 200 patients with probable Alzheimer's … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 19, 2014 Category: Primary Care Source Type: news

Citalopram Reduces Agitation in Patients With Alzheimer's Citalopram Reduces Agitation in Patients With Alzheimer's
Results of the CitAD trial show 30 mg daily moderates agitation in AD but also affects cognition, can cause electrocardiography changes, and is no longer recommended in older adults. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - February 19, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Antidepressant Celexa May Help Ease Alzheimer's Linked Agitation
Study finds it might be safer alternative to standard antipsychotics Source: HealthDay Related MedlinePlus Pages: Alzheimer's Disease, Antidepressants (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - February 18, 2014 Category: Consumer Health News Source Type: news

Celexa Eases Alzheimer's Agitation, But Safety Unclear (CME/CE)
(MedPage Today) -- A well-known antidepressant reduced agitation in people with probable Alzheimer's disease, but with some adverse cardiac and cognitive effects, researchers reported. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 18, 2014 Category: Psychiatry Source Type: news

Citalopram Side Effects (Brand Name Celexa)
List of Citalopram side effects. Citalopram (brand name Celexa) is an antidepressant sometimes prescribed in the treatment of bipolar disorder and other mood disorders. You need to know about potential side effects if you are taking or considering taking this medication. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - August 2, 2013 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Celexa (Citalopram) - Medication Profile
Celexa - generic citalopram - is a medication used to treat depression. Celexa is a member of the SSRI drug family. These drugs work by making more serotonin available between nerve cells, which has been shown to ease depression. Article covers the benefits of Celexa, precautions and warnings, and information regarding pregnancy and Celexa. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 30, 2013 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Citalopram and the QT Interval RevisitedCitalopram and the QT Interval Revisited
Contrasting with FDA warnings, does this study suggest that they are wrong about citalopram? Medscape Psychiatry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 19, 2013 Category: Consumer Health News Tags: Psychiatry Viewpoint Source Type: news

FDA Citalopram Warning 'Without Merit'FDA Citalopram Warning 'Without Merit'
A recent FDA warning about an increased risk for cardiovascular events and mortality with higher doses of the antidepressant citalopram is "without merit," new research suggests. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - June 6, 2013 Category: Psychiatry Tags: Psychiatry News Source Type: news

citalopram, Celexa
Title: citalopram, CelexaCategory: MedicationsCreated: 2/2/1999 10:38:00 PMLast Editorial Review: 5/31/2013 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - May 31, 2013 Category: Psychiatry Source Type: news

List of dangerous antidepressants that cause sudden death is rapidly expanding
The list of antidepressants that can cause sudden death is growing exponentially, with citalopram - under the brand names Celexa and Cipramil - the latest such drug to be added, according to a new study. The research, published recently in the British Medical Journal... (Source: NaturalNews.com)
Source: NaturalNews.com - May 21, 2013 Category: Consumer Health News Source Type: news

Warning By FDA Against High Dose Antidepressant Prescription May Be Unwarranted
The U.S. Food and Drug Administration's warning that high doses of the antidepressant citalopram can cause potentially serious abnormal heart rhythms might be doing more harm than good. In 2011, the FDA attached a warning to the drug, also known as Celexa, based on data linking higher doses of the drug to potentially fatal abnormal changes in the electrical activity of the heart... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 7, 2013 Category: Consumer Health News Tags: Depression Source Type: news

FDA warning against high dose antidepressant prescription may be unwarranted, study finds
(University of Michigan Health System) A new Ann Arbor VA Healthcare System and University of Michigan study calls into question the FDA's warning against high dosages of citalopram after finding no increased risk for abnormal heart rhythms or death in patients who took daily doses of more than 40 milligrams before or after the warning took effect. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 3, 2013 Category: Global & Universal Source Type: news

Contributory and incidental blood concentrations in deaths involving citalopram - Darke S, Torok M, Duflou J.
All cases presenting to the New South Wales Department of Forensic Medicine between January 1, 2001 and December 31, 2010 in which citalopram was detected were retrieved. A total of 348 cases were identified. Citalopram contributed to death in 21.0%, and w... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - February 26, 2013 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Panic Attacks with Celexa?
LOOKINOUT asked the following question on the forum:  "I started Celexa about a week ago and started noticing a positive difference right away -- reuduced obsessive thoughts, lowered depression, more motivation and interest in the world, and more restful sleep. However, I am having ONE ugly problem with this drug -- about every other day I seem to experience a period of panic-type anxiety that lasts anywhere from 10 minutes to an hour."...Read Full Post (Source: About.com Depression)
Source: About.com Depression - February 25, 2013 Category: Psychiatry Source Type: news

NHS Evidence expert commentary: Citalopram for the treatment of depression
Source: NHS Evidence Area: News The February edition of 'Eyes on Evidence', the free monthly e-bulletin from NHS Evidence covering major new published evidence as it emerges with an explanation about what it means for current practice, includes an expert commentary on new data from a Cochrane review of 37 RCTs which assessed the efficacy, acceptability and tolerability of citalopram compared with other antidepressants in the acute-phase treatment of major depression in over 6000 patients.   Citalopram did not differ from most antidepressants in the primary outcome, the number of patients who responded to treatmen...
Source: NeLM - Mental Health - February 14, 2013 Category: Psychiatry Source Type: news

Antidepressants Linked to Increased Risk for Heart Arrhythmia, Sudden Death
Patients who are taking high doses of two antidepressants - citalopram (Celexa) and escitalopram (Lexapro) - could be at risk for developing QT-interval prolongation, according to a study published online on January 29, 2013 in the British Medical Journal....Read Full Post (Source: About.com Depression)
Source: About.com Depression - February 12, 2013 Category: Psychiatry Source Type: news

Antidepressant link to heart changes confirmed
Conclusion This study shows a link between three antidepressants (two SSRIs and one tricyclic) and prolonged QT interval (a risk factor for rare but serious heart rhythm problems). The study did not assess the risk of these heart rhythm problems directly (which is difficult to measure because of their rarity). The researchers point out that the recent FDA warning over the risks of citalopram was based on its association with prolonged QT interval only, and “in spite of the epidemiological data showing no difference in risk for arrhythmia [heart rhythm abnormality]”. The researchers say that certain SSRIs were n...
Source: NHS News Feed - January 31, 2013 Category: Consumer Health News Tags: Medication Mental health Source Type: news

Antidepressant Contribution To Arrhythmia Risk Clarified By Electronic Health Record Analysis
A 2011 warning from the U.S. Food and Drug Administration about the popular antidepressant citalopram (Celexa) left many patients and physicians with more questions than answers. Now an analysis of the medical records of more than 38,000 patients by Massachusetts General Hospital (MGH) investigators clarifies the contribution of citalopram and other antidepressants to lengthening of the QT interval, an aspect of the heart's electrical activity that - when prolonged - may increase the risk of dangerous arrhythmias... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Depression Source Type: news

Slight risk of QT-interval prolongation found with two antidepressants
The risk seen at high doses of citalopram and escitalopram, but not a number of other antidepressants, could put patients at risk for malignant ventricular arrhythmias. (Source: theHeart.org)
Source: theHeart.org - January 30, 2013 Category: Cardiology Source Type: news

Antidepressants Celexa, Lexapro Tied to Irregular Heartbeat: Study
But the occurrence is rare, and alternatives exist, experts say (Source: WebMD Health)
Source: WebMD Health - January 30, 2013 Category: Consumer Health News Source Type: news

Antidepressant Link To Heart Rhythm Abnormalities No Cause For Alarm
Some antidepressants have been linked to a long QT, which may increase the likelihood of having a serious heart rhythm abnormality. However, as they are extremely rare, the benefits offered by antidepressant far outweigh the risks and patients should not be alarmed, says the British Heart Foundation. American scientists demonstrated an association between the antidepressants citalopram and escitalopram and a long QT interval in some patients' ECGs (electrocardiograms). They reported their findings in the BMJ (British Medical Journal)... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 30, 2013 Category: Consumer Health News Tags: Depression Source Type: news