Rotational ThromboElastometry-guided blood component administration versus standard of care in patients with Cirrhosis and coagulopathy undergoing Invasive ProcEdures (RECIPE): study protocol for a randomised controlled trial
DiscussionWe anticipate that this project will lead to improved prognostication of patients with cirrhosis, in terms of their peri-procedural bleeding risk. We hope to show that a significant proportion of cirrhotic patients, deemed coagulopathic on the basis of standard coagulation tests such as INR and platelet count, are actually in a haemostatic balance and thus do not require prophylactic blood product, leading to decreased and more efficient blood component use.Trial registrationRECIPE has been prospectively registered with the Australia and New Zealand Clinical Trials Registry on the 30th April 2019 (ACTRN1261900...
Source: Trials - August 11, 2023 Category: Research Source Type: clinical trials
Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)
Condition: Decompensated Cirrhosis Intervention: Biological: Human Umbilical Cord-derived Mesenchymal Stem Cells Sponsors: Beijing 302 Hospital; Wuhan Optics Valley Zhongyuan Pharmaceutical Co., Ltd., Hubei, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Molecular Mechanism of Exercise in Cirrhosis
Condition: Cirrhosis, Liver Interventions: Other: Endurance Training 3 times per week; Other: Resistance Exercise; Other: Standard of Care Sponsor: The Cleveland Clinic Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)
Condition: Decompensated Cirrhosis Intervention: Biological: Human Umbilical Cord-derived Mesenchymal Stem Cells Sponsors: Beijing 302 Hospital; Wuhan Optics Valley Zhongyuan Pharmaceutical Co., Ltd., Hubei, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Molecular Mechanism of Exercise in Cirrhosis
Condition: Cirrhosis, Liver Interventions: Other: Endurance Training 3 times per week; Other: Resistance Exercise; Other: Standard of Care Sponsor: The Cleveland Clinic Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)
Condition: Decompensated Cirrhosis Intervention: Biological: Human Umbilical Cord-derived Mesenchymal Stem Cells Sponsors: Beijing 302 Hospital; Wuhan Optics Valley Zhongyuan Pharmaceutical Co., Ltd., Hubei, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Molecular Mechanism of Exercise in Cirrhosis
Condition: Cirrhosis, Liver Interventions: Other: Endurance Training 3 times per week; Other: Resistance Exercise; Other: Standard of Care Sponsor: The Cleveland Clinic Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-1b)
Condition: Decompensated Cirrhosis Intervention: Biological: Human Umbilical Cord-derived Mesenchymal Stem Cells Sponsors: Beijing 302 Hospital; Wuhan Optics Valley Zhongyuan Pharmaceutical Co., Ltd., Hubei, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 9, 2023 Category: Research Source Type: clinical trials
