Popeye Sign in Hereditary Transthyretin Amyloidosis
This case report describes a 63-year-old man who developed dysesthesia in his feet and was misdiagnosed with chronic inflammatory demyelinating polyradiculoneuropathy. (Source: JAMA Neurology)
Source: JAMA Neurology - July 3, 2023 Category: Neurology Source Type: research

Chronic inflammatory demyelinating polyneuropathy after SARS-CoV2 vaccination: update of the literature and patient characterization
AbstractSince the beginning of worldwide vaccination against COVID-19 disease, some reports have revealed a possible relationship between SARS CoV2 vaccination and chronic inflammatory demyelinating polyneuropathy (CIDP). We reviewed the available evidences regarding this topic, adding three new cases to those reported so far, with the purpose to outline the characteristics of these post-vaccinal CIDP. Seventeen subjects were studied. A total of 70.6% of CIDP cases were related to viral vector vaccines, most occurring after the administration of the first dose. CIDPs that occurred after the second dose (17%) were temporall...
Source: Immunologic Research - July 3, 2023 Category: Allergy & Immunology Source Type: research

The diagnostic value of quantitative assessment of MR neurography in chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta-analysis
CONCLUSION: Quantitative MRN has considerable diagnostic value in CIDP patients with accuracy and reliability. FA and CSA can be promising parameters in the future diagnosis of CIDP patients.ADVANCES IN KNOWLEDGE: This is the first meta-analysis of quantitative MRN in the diagnosis of CIDP.We have selected reliable parameters with cut-off value and providednew insights for subsequent diagnosis of CIDP.PMID:37393524 | DOI:10.1259/bjr.20221037 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 2, 2023 Category: Radiology Authors: Haofeng Chen Xinyue Huang Yifang Bao Chongbo Zhao Jie Lin Source Type: research

The diagnostic value of quantitative assessment of MR neurography in chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta-analysis
CONCLUSION: Quantitative MRN has considerable diagnostic value in CIDP patients with accuracy and reliability. FA and CSA can be promising parameters in the future diagnosis of CIDP patients.ADVANCES IN KNOWLEDGE: This is the first meta-analysis of quantitative MRN in the diagnosis of CIDP.We have selected reliable parameters with cut-off value and providednew insights for subsequent diagnosis of CIDP.PMID:37393524 | DOI:10.1259/bjr.20221037 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - July 2, 2023 Category: Radiology Authors: Haofeng Chen Xinyue Huang Yifang Bao Chongbo Zhao Jie Lin Source Type: research

Krebs von den Lungen-6 (KL-6) in cerebrospinal fluid from neurosarcoidosis patients
DISCUSSION: KL-6 is a high MW protein, under physiological conditions it is unlikely to cross the blood-brain barrier. We found KL-6 in CSF from NS and not from ND and DM patients. The finding sustains the specificity of changes in KL-6 in this granulomatous disease, suggesting it as a candidate biomarker for recognition of NS.PMID:37382078 | DOI:10.36141/svdld.v40i2.12900 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - June 29, 2023 Category: Respiratory Medicine Authors: Silvia Bocci Miriana D'Alessandro Laura Bergantini Alfonso Cerase Monica Ulivelli Paola Rottoli Dalila Cavallaro Sara Gangi Elena Bargagli Fabio Giannini Source Type: research