High Prevalence of Undetected Hypertension Found in Bangladesh
The salinity of the water in coastal Bangladesh contributes to high blood pressure. Credit: Rafiqul Islam/IPSBy Rafiqul IslamDHAKA, Nov 7 2023 (IPS) Since her childhood, Parveen Begum, 52, has been adding extra salt while eating her meals. However, she did not know that this contributed to high blood pressure.
Recently, she suffered severe headaches, forcing her to go to a physician, and when the doctor checked her health, he she had hypertension.
“I could not take my daily meals without taking additional salt, which helped develop the chronic disease in my health. Now I have to take medicines for blood pressure regular...
Source: IPS Inter Press Service - Health - November 7, 2023 Category: International Medicine & Public Health Authors: Rafiqul Islam Tags: Asia-Pacific Health Humanitarian Emergencies Sustainable Development Goals TerraViva United Nations Women's Health Bangladesh IPS UN Bureau IPS UN Bureau Report Source Type: news
Hydrocodone, oxycodone, and morphine metabolism and drug-drug interactions - Coates S, Lazarus P.
Awareness of drug interactions involving opioids is critical for patient treatment as they are common therapeutics used in numerous care settings, including both chronic and disease-related pain. Not only do opioids have narrow therapeutic indexes and are ... (Source: SafetyLit)
Source: SafetyLit - October 31, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche announces EMBARK trial in Duchenne muscular dystrophy (DMD) did not reach primary endpoint, but shows positive efficacy outcomes on all timed functional key endpoints
This study is ongoing.Study 301 (EMBARK), a Phase 3 global, randomised, double-blinded and placebo-controlled study of Elevidys in ambulatory Duchenne patients aged 4-<8 years old.The ENVOL trial (Study 302) a Phase 2 study in children with Duchenne. The study aims to enrol 21 participants who are under 4 years of age, including newborns. Not yet started.The ENVISION trial (Study 303), a Phase 3 study in older ambulatory/non-ambulatory patients which is now recruiting.The EXPEDITION long-term (5 year) follow up study (Study 305) of participants who have received Elevidys in a previous clinical study, which is not yet re...
Source: Roche Media News - October 31, 2023 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche announces EMBARK trial in Duchenne muscular dystrophy (DMD) did not reach primary endpoint, but shows positive efficacy outcomes on all timed functional key endpoints
This study is ongoing.Study 301 (EMBARK), a Phase 3 global, randomised, double-blinded and placebo-controlled study of Elevidys in ambulatory Duchenne patients aged 4-<8 years old.The ENVOL trial (Study 302) a Phase 2 study in children with Duchenne. The study aims to enrol 21 participants who are under 4 years of age, including newborns. Not yet started.The ENVISION trial (Study 303), a Phase 3 study in older ambulatory/non-ambulatory patients which is now recruiting.The EXPEDITION long-term (5 year) follow up study (Study 305) of participants who have received Elevidys in a previous clinical study, which is not yet re...
Source: Roche Investor Update - October 31, 2023 Category: Pharmaceuticals Source Type: news
Spinal Surgery Redux: Advancing Our Approach to Back Pain
(MedPage Today) -- Lower back pain has been the leading cause of years lived with disability since 1990, and it continues to be a significant concern for public health on a global scale. In the U.S., 72.3 million adults currently suffer from chronic... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - October 30, 2023 Category: Rheumatology Source Type: news
Are sexual assaults related to functional somatic disorders? A cross-sectional study - Jacobsen SA, Frostholm L, Buhmann CB, Petersen MW, Ørnbøl E, Dantoft TM, Bjerregaard AA, Eplov LF, Carstensen TBW.
This study investigated associations between SA and FSD, conceptualized as bodily distress syndrome (BDS), and five functional somatic syndromes (FSSs): chronic widespread pain (CWP), irrita... (Source: SafetyLit)
Source: SafetyLit - October 30, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Severe and fatal fentanyl poisonings from transdermal systems after on-skin and ingestion application - Sommerfeld-Klatta K, Jiers W, Łukasik-Głebocka M, Tężyk A, Dolińska-Kaczmarek K, Walter K, Swiderski P, Rzepczyk S, Zielińska-Psuja B, Zaba C.
In recent years, the administration of fentanyl (FNTL) implicitly in transdermal drug delivery systems (TDDS) has vastly increased in chronic pain treatment. Non-medical and uncontrolled use of FNTL in TFDS (transdermal fentanyl delivery systems) may revea... (Source: SafetyLit)
Source: SafetyLit - October 30, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Whole Body Cryotherapy (WBC): A "Cool" Trend that Lacks Evidence, Poses Risks
A growing number of wellness centers, spas, and sports rehabilitation centers are promoting whole body cryotherapy (WBC) as an effective way to treat chronic pain and a host of other medical conditions, and help you lose weight. However, the FDA has not cleared or approved any WBC machines for any m (Source: FDA Consumer Health Information Updates)
Source: FDA Consumer Health Information Updates - October 23, 2023 Category: Consumer Health News Authors: FDA Source Type: news
Whole Body Cryotherapy (WBC): A " Cool " Trend that Lacks Evidence, Poses Risks
A growing number of wellness centers, spas, and sports rehabilitation centers are promoting whole body cryotherapy (WBC) as an effective way to treat chronic pain and a host of other medical conditions, and help you lose weight. However, the FDA has not cleared or approved any WBC machines for any m (Source: FDA Consumer Health Information Updates)
Source: FDA Consumer Health Information Updates - October 23, 2023 Category: Consumer Health News Authors: FDA Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche enters into a definitive agreement to acquire Telavant including rights to novel TL1A directed antibody (RVT-3101) for the treatment of inflammatory bowel disease from Roivant
Roche will gain the rights to develop, manufacture and commercialise RVT-3101 in the US and Japan for the treatment of inflammatory bowel disease and potentially multiple other diseasesRVT-3101 is a Phase 3-ready antibody with first-in-class and best-in-disease potential, a novel mode of action and strong Phase 2b data in ulcerative colitisRoche will also obtain an option to enter into a global collaboration with Pfizer on a next-generation p40/TL1A directed bispecific antibody, currently in Phase 1Under the terms of the agreement, Roche will pay a purchase price of US$ 7.1 billion upfront and a near-term milestone payment...
Source: Roche Investor Update - October 23, 2023 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche enters into a definitive agreement to acquire Telavant including rights to novel TL1A directed antibody (RVT-3101) for the treatment of inflammatory bowel disease from Roivant
Roche will gain the rights to develop, manufacture and commercialise RVT-3101 in the US and Japan for the treatment of inflammatory bowel disease and potentially multiple other diseasesRVT-3101 is a Phase 3-ready antibody with first-in-class and best-in-disease potential, a novel mode of action and strong Phase 2b data in ulcerative colitisRoche will also obtain an option to enter into a global collaboration with Pfizer on a next-generation p40/TL1A directed bispecific antibody, currently in Phase 1Under the terms of the agreement, Roche will pay a purchase price of US$ 7.1 billion upfront and a near-term milestone payment...
Source: Roche Media News - October 23, 2023 Category: Pharmaceuticals Source Type: news
Can cannabis-based meds help people manage oral cancer pain?
Dr. Igor Spigelman, chair of the biosystems and function section at the UCLA School of Dentistry, has received a $5 million grant from the National Institute of Neurological Disorders and Stroke for research aimed at developing a non-addictive cannabis-based pain medication for oral cancer patients.The five-year multidisiplinary study will leverage the collective expertise of researchers from the dental school, UCLA’s department of chemistry and biochemistry and department of psychiatry and biobehavioral sciences, and New York University. It also aligns with a nationwide effort to curb opioid misuse and addiction while...
Source: UCLA Newsroom: Health Sciences - October 20, 2023 Category: Universities & Medical Training Source Type: news
Mayo Clinic Q and A: How to support a loved one who has chronic pain
DEAR MAYO CLINIC: My spouse suffers from chronic pain after a back injury five years ago. The pain affects his ability to work and enjoy day-to-day activities with our family. Seeing him in pain and not knowing how to help is difficult for me. How can I support him on the challenging days when the pain is more severe and encourage him on the good days? ANSWER: For millions of people, living with chronic pain… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 19, 2023 Category: Databases & Libraries Source Type: news
Prevalence of suicidal behavior in patients with chronic pain: a systematic review and meta-analysis of observational studies - Kwon CY, Lee B.
OBJECTIVE: Chronic pain is a leading cause of disability, severely impairing an individual's daily activity and quality of life. In addition, this condition may contribute to suicidal thoughts by leading to neuropsychological impairments, a perceived lack ... (Source: SafetyLit)
Source: SafetyLit - October 18, 2023 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Fear avoidance, fear of falling, and pain disability in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders - Chuchin JD, Ornstein TJ.
PURPOSE: Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) are understudied conditions characterized by hallmark hypermobility and chronic pain. Disease manifestations lead to significant disability. Understanding predict... (Source: SafetyLit)
Source: SafetyLit - October 18, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
