Can cannabis-based meds help people manage oral cancer pain?
Dr. Igor Spigelman, chair of the biosystems and function section at the UCLA School of Dentistry, has received a $5 million grant from the National Institute of Neurological Disorders and Stroke for research aimed at developing a non-addictive cannabis-based pain medication for oral cancer patients.The five-year multidisiplinary study will leverage the collective expertise of researchers from the dental  school, UCLA’s department of chemistry and biochemistry and department of psychiatry and biobehavioral sciences, and New York University. It also aligns with a nationwide effort to curb opioid misuse and addiction while...
Source: UCLA Newsroom: Health Sciences - October 20, 2023 Category: Universities & Medical Training Source Type: news

Mayo Clinic Q and A: How to support a loved one who has chronic pain
DEAR MAYO CLINIC: My spouse suffers from chronic pain after a back injury five years ago. The pain affects his ability to work and enjoy day-to-day activities with our family. Seeing him in pain and not knowing how to help is difficult for me. How can I support him on the challenging days when the pain is more severe and encourage him on the good days? ANSWER: For millions of people, living with chronic pain… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 19, 2023 Category: Databases & Libraries Source Type: news

Prevalence of suicidal behavior in patients with chronic pain: a systematic review and meta-analysis of observational studies - Kwon CY, Lee B.
OBJECTIVE: Chronic pain is a leading cause of disability, severely impairing an individual's daily activity and quality of life. In addition, this condition may contribute to suicidal thoughts by leading to neuropsychological impairments, a perceived lack ... (Source: SafetyLit)
Source: SafetyLit - October 18, 2023 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Fear avoidance, fear of falling, and pain disability in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders - Chuchin JD, Ornstein TJ.
PURPOSE: Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) are understudied conditions characterized by hallmark hypermobility and chronic pain. Disease manifestations lead to significant disability. Understanding predict... (Source: SafetyLit)
Source: SafetyLit - October 18, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Suicidal ideation in female individuals with fibromyalgia and comorbid obesity: prevalence and association with clinical, pain-related and psychological factors - Varallo G, Scarpina F, Arnison T, Giusti EM, Tenti M, Rapelli G, Cattivelli R, Landi G, Tossani E, Grandi S, Franceschini C, Baldini V, Plazzi G, Capodaglio P, Castelnuovo G.
OBJECTIVE: Individuals with fibromyalgia report alarming levels of suicidal ideation, and comorbidity with other chronic health conditions such as obesity - a risk factor for suicidal ideation per se- could further complicate the clinical picture. The aim ... (Source: SafetyLit)
Source: SafetyLit - October 18, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Cannabis Laws Linked to CUD in Adults With Chronic Pain Cannabis Laws Linked to CUD in Adults With Chronic Pain
Medical and recreational cannabis laws in the US are associated with increased prevalence of cannabis use disorder, especially among older adults with chronic pain.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - October 16, 2023 Category: Internal Medicine Tags: Neurology & Neurosurgery News Source Type: news

Chronic pain in the lower extremities and low back is associated with recurrent falls in community-dwelling Japanese people aged 40-74 years - Nagashima Y, Kitamura K, Watanabe Y, Kabasawa K, Takahashi A, Saito T, Kobayashi R, Oshiki R, Takachi R, Tsugane S, Yamazaki O, Watanabe K, Nakamura K.
OBJECTIVE: To determine the longitudinal association between chronic pain in the lower extremities and low back and the odds of recurrent falls in middle-aged and older people. DESIGN: A cohort study. SETTING: Communities in Japan. PARTICIPANTS: Pa... (Source: SafetyLit)
Source: SafetyLit - October 16, 2023 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

The roles of depression, life control and affective distress on treatment attendance and perceived disability in chronic back pain sufferers throughout the duration of the condition - Oraison HM, Loton D, Kennedy GA.
The aims of this study were to examine psychological factors that predict treatment seeking and disability over the total duration of experiencing back pain. A sample of 201 adults experiencing chronic back pain was recruited through health professionals a... (Source: SafetyLit)
Source: SafetyLit - October 16, 2023 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

Systematic review of  injuries and chronic musculoskeletal pain among high-speed boat operators - Ullman CJ, Hengst D, Rolfson O, Myers S, Robinson Y.
INTRODUCTION: High-speed boat operators constitute a population at risk of work-related injuries and disabilities. This review aimed to summarize the available knowledge on workplace-related injuries and chronic musculoskeletal pain among high-speed boat o... (Source: SafetyLit)
Source: SafetyLit - October 16, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Four SNPs Linked to Chronic Complex Regional Pain Syndrome Type 1
FRIDAY, Oct. 13, 2023 -- Four single nucleotide polymorphisms (SNPs) in four genes are associated with chronic complex regional pain syndrome type 1 (CRPS-1), according to a study published online Oct. 10 in the Journal of Medical Genetics. Samiha... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 13, 2023 Category: Pharmaceuticals Source Type: news

Late-breaking data for Roche ’s BTK inhibitor fenebrutinib show brain penetration and significant reduction in lesions in patients with relapsing multiple sclerosis
New data from Phase II FENopta study in relapsing multiple sclerosis (RMS) show fenebrutinib crosses the blood-brain barrier with the potential to act directly on the chronic inflammation related to multiple sclerosis (MS)More than 90% relative reduction in new/enlarging T2 lesions and new T1 gadolinium-enhancing (Gd+) lesions with fenebrutinib beginning at 8 weeksThe safety profile of fenebrutinib was consistent with previous and ongoing clinical trials across more than 2,500 people to dateBasel, 13 October 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data from the Phase II FENopta study showing that inve...
Source: Roche Media News - October 13, 2023 Category: Pharmaceuticals Source Type: news

Late-breaking data for Roche ’s BTK inhibitor fenebrutinib show brain penetration and significant reduction in lesions in patients with relapsing multiple sclerosis
New data from Phase II FENopta study in relapsing multiple sclerosis (RMS) show fenebrutinib crosses the blood-brain barrier with the potential to act directly on the chronic inflammation related to multiple sclerosis (MS)More than 90% relative reduction in new/enlarging T2 lesions and new T1 gadolinium-enhancing (Gd+) lesions with fenebrutinib beginning at 8 weeksThe safety profile of fenebrutinib was consistent with previous and ongoing clinical trials across more than 2,500 people to dateBasel, 13 October 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced new data from the Phase II FENopta study showing that inve...
Source: Roche Investor Update - October 13, 2023 Category: Pharmaceuticals Source Type: news

Dr Michael Mosley shares the 'gentle' exercise that could improve core strength in old age
It could also help tackle "chronic" lower back pain, he recommended. (Source: Daily Express - Health)
Source: Daily Express - Health - October 12, 2023 Category: Consumer Health News Source Type: news

ACR releases updated appropriateness criteria
The American College of Radiology (ACR) has released an update to its Appropriateness Criteria, which includes nine new and nine revised topics. The criteria in total include 233 diagnostic imaging and interventional radiology topics with more than 1,100 clinical variants covering more than 3,000 clinical scenarios. All topics include a narrative, an evidence table, and a literature search summary. The ACR said the criteria aim to assist referring physicians and other providers in making the most appropriate imaging or treatment decisions for specific clinical conditions. The following are the new topics: Imaging of In...
Source: AuntMinnie.com Headlines - October 10, 2023 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Source Type: news

Children with chronic non-cancer pain and their families ’ experiences and understanding of their condition, pain services and treatments: a meta-ethnography
Thursday, October 5, 2023 (Source: Cochrane News and Events)
Source: Cochrane News and Events - October 5, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news