Immunogenicity of partial doses of live oral cholera vaccine CVD 103-HgR in children in the United States
Vaccine. 2023 Mar 21:S0264-410X(23)00260-8. doi: 10.1016/j.vaccine.2023.03.013. Online ahead of print.ABSTRACTIn a phase 4, placebo-controlled, double-blind, multi-center study performed to assess the immunogenicity of a single oral dose of live, attenuated cholera vaccine, volunteers aged 2-17 years were randomized 6:1 to receive 1 × 109 colony forming units of PXVX0200 or placebo. In the subset of subjects who consumed < 80 % of the vaccine dose, seroconversion rates were calculated and stratified by amount consumed. Of 468 subjects dosed, a subset of 33 (7 %) received < 80 % of the vaccine dose. SVA seroconversio...
Source: Vaccine - March 23, 2023 Category: Allergy & Immunology Authors: James M McCarty David Cassie Lisa Bedell Source Type: research
Immunogenicity of partial doses of live oral cholera vaccine CVD 103-HgR in children in the United States
Vaccine. 2023 Mar 21:S0264-410X(23)00260-8. doi: 10.1016/j.vaccine.2023.03.013. Online ahead of print.ABSTRACTIn a phase 4, placebo-controlled, double-blind, multi-center study performed to assess the immunogenicity of a single oral dose of live, attenuated cholera vaccine, volunteers aged 2-17 years were randomized 6:1 to receive 1 × 109 colony forming units of PXVX0200 or placebo. In the subset of subjects who consumed < 80 % of the vaccine dose, seroconversion rates were calculated and stratified by amount consumed. Of 468 subjects dosed, a subset of 33 (7 %) received < 80 % of the vaccine dose. SVA seroconversio...
Source: Vaccine - March 23, 2023 Category: Allergy & Immunology Authors: James M McCarty David Cassie Lisa Bedell Source Type: research
Cholera in Haiti: A public health challenge in the Dominican Republic and Americas Region
Rev Panam Salud Publica. 2023 Mar 20;47:e60. doi: 10.26633/RPSP.2023.60. eCollection 2023.NO ABSTRACTPMID:36945249 | PMC:PMC10022829 | DOI:10.26633/RPSP.2023.60 (Source: Pan American Journal of Public Health)
Source: Pan American Journal of Public Health - March 22, 2023 Category: International Medicine & Public Health Authors: Bienvenido A Veras-Est évez Helena J Chapman Source Type: research
Decussating axons segregate within the anterior core of the primate optic chiasm
Conclusions
A distinct, central compartment located within the anterior two-thirds of the optic chiasm contains only crossing fibres. Sellar tumours focus their compressive force on this portion of the structure, explaining why they so often produce visual field loss in the temporal fields. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 22, 2023 Category: Opthalmology Authors: Horton, J. C., Dilbeck, M. D., Economides, J. R. Tags: Review Source Type: research
Resistance of Vibrio cholera to antibiotics that inhibit cell wall synthesis: A systematic review and meta-analysis
Discussion: Aztreonam, cefepime, and imipenem are the most efficient V. cholera cell wall synthesis inhibitors. There has been an increase in resistance to antibiotics such as cephalothin, ceftriaxone, amoxicillin, and meropenem. Over the years, resistance to penicillin, ceftazidime, and cefotaxime, has decreased. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 20, 2023 Category: Drugs & Pharmacology Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - March 17, 2023 Category: Biomedical Science Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: Indian J Med Res)
Source: Indian J Med Res - March 17, 2023 Category: Research Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
A Molecular and Epidemiological Study of Cholera Outbreak in Sulaymaniyah Province, Iraq, in 2022
In this study, we conducted a molecular and epidemiological study of the recent outbreak in the city of Sulaymaniyah in Iraq. Based on the bacteriological, serological, and molecular identification of the bacterium, it was shown that V. cholerae O1 serotype Ogawa caused the disease. Additionally, the number of positive cholera cases were higher in June compared to July (391 positive cases in June and 23 in July). Moreover, the majority (> 60%) of the cholera cases were recorded among 20-44-year-old people in both months; however, there was no significant difference in the patient genders diagnosed every month. Overall, ...
Source: Polish Journal of Microbiology - March 17, 2023 Category: Microbiology Authors: Dana Khdr Sabir Zhwan Talib Hama Karzan Jalal Salih Karzan Ghafur Khidhir Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - March 17, 2023 Category: Biomedical Science Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: Indian J Med Res)
Source: Indian J Med Res - March 17, 2023 Category: Research Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
A Molecular and Epidemiological Study of Cholera Outbreak in Sulaymaniyah Province, Iraq, in 2022
In this study, we conducted a molecular and epidemiological study of the recent outbreak in the city of Sulaymaniyah in Iraq. Based on the bacteriological, serological, and molecular identification of the bacterium, it was shown that V. cholerae O1 serotype Ogawa caused the disease. Additionally, the number of positive cholera cases were higher in June compared to July (391 positive cases in June and 23 in July). Moreover, the majority (> 60%) of the cholera cases were recorded among 20-44-year-old people in both months; however, there was no significant difference in the patient genders diagnosed every month. Overall, ...
Source: Polish Journal of Microbiology - March 17, 2023 Category: Microbiology Authors: Dana Khdr Sabir Zhwan Talib Hama Karzan Jalal Salih Karzan Ghafur Khidhir Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - March 17, 2023 Category: Biomedical Science Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
A retrospective analysis of serological & amp; molecular testing data on dengue fever in Kolkata & amp; adjacent districts during 2016-2019
CONCLUSIONS: Dengue continues to be an important cause of AFI in the region and round-the-year preventive measures are required for its control. Serotype switching is alarming and should be monitored routinely.PMID:36926776 | DOI:10.4103/ijmr.IJMR_2612_19 (Source: Indian J Med Res)
Source: Indian J Med Res - March 17, 2023 Category: Research Authors: Agniva Majumdar Rajarshi Gupta Ananya Chatterjee Hasina Banu Madhumonti Biswas Rudrak Gupta Soumen Mukherjee Provash Sadhukhan Shanta Dutta Source Type: research
