Zeta potential of Z-DNA: A new signature to study B-Z transition in linear and branched DNA
In this study, for the first time we discover the zeta potential difference between B-DNA and lanthanum chloride-induced Z-DNA. A series of linear repeat i.e. (CG)n and (GC)n DNA as well as branched DNA (bDNA) structures was used for the B-to-Z DNA transition. Herein, the positive zeta potential of Z-DNA has been demonstrated as a powerful tool to discriminate between B-form and Z-form of DNA. The generality of the approach has been validated both in linear and bDNA nanostructures. Thus, we suggest zeta potential can be used as an ideal signature for the left-handed Z-DNA.PMID:38554916 | DOI:10.1016/j.ijbiomac.2024.131238 ...
Source: International Journal of Biological Macromolecules - March 30, 2024 Category: Biochemistry Authors: Partha S Nial Umakanta Subudhi Source Type: research
Tunable durian seed gum-derived eutectogel as a novel coating material: Rheological, thermal, textural and barrier properties for enhanced food preservation
Int J Biol Macromol. 2024 Mar 28:131201. doi: 10.1016/j.ijbiomac.2024.131201. Online ahead of print.ABSTRACTAs a promising green and sustainable coating material, gum was extracted from durian seed to produce eutectogel, which the properties were tunable using natural deep eutectic solvent (NADES). Ten different eutectogels were successfully synthesized using durian seed gum (DSG) and xanthan gum (XG) gelators at different composition (5, 10, 15 %) to gel choline chloride-glucose (1:1), choline chloride-fructose (1:2) and betaine-glucose-water (1:1:1) NADESs. Results revealed that eutectogel was non-Newtonian and weak gel ...
Source: International Journal of Biological Macromolecules - March 30, 2024 Category: Biochemistry Authors: Zhi Ling Chew Qi Qi Koh Eng Eng Chu Yin Leng Kua Suyin Gan Khang Wei Tan Terri Zhuan Ean Lee Source Type: research
Bovine serum albumin uptake and polypeptide disaggregation studies of hypoglycemic ruthenium(II) uracil Schiff-base complexes
J Inorg Biochem. 2024 Mar 27;255:112541. doi: 10.1016/j.jinorgbio.2024.112541. Online ahead of print.ABSTRACTOur prior studies have illustrated that the uracil ruthenium(II) diimino complex, [Ru(H3ucp)Cl(PPh3)] (1) (H4ucp = 2,6-bis-((6-amino-1,3-dimethyluracilimino)methylene)pyridine) displayed high hypoglycemic effects in diet-induced diabetic rats. To rationalize the anti-diabetic effects of 1, three new derivatives have been prepared, cis-[Ru(bpy)2(urdp)]Cl2 (2) (urdp = 2,6-bis-((uracilimino)methylene)pyridine), trans-[RuCl2(PPh3)(urdp)] (3), and cis-[Ru(bpy)2(H4ucp)](PF6)2 (4). Various physicochemical techniques were u...
Source: Journal of Inorganic Biochemistry - March 30, 2024 Category: Biochemistry Authors: Daniel M Makanyane Sanam Maikoo Fanie R Van Heerden Lydia Rhyman Ponnadurai Ramasami Lindokuhle P Mabuza Phikelelani Ngubane Andile Khathi Allen Mambanda Irvin N Booysen Source Type: research
Bovine serum albumin uptake and polypeptide disaggregation studies of hypoglycemic ruthenium(II) uracil Schiff-base complexes
J Inorg Biochem. 2024 Mar 27;255:112541. doi: 10.1016/j.jinorgbio.2024.112541. Online ahead of print.ABSTRACTOur prior studies have illustrated that the uracil ruthenium(II) diimino complex, [Ru(H3ucp)Cl(PPh3)] (1) (H4ucp = 2,6-bis-((6-amino-1,3-dimethyluracilimino)methylene)pyridine) displayed high hypoglycemic effects in diet-induced diabetic rats. To rationalize the anti-diabetic effects of 1, three new derivatives have been prepared, cis-[Ru(bpy)2(urdp)]Cl2 (2) (urdp = 2,6-bis-((uracilimino)methylene)pyridine), trans-[RuCl2(PPh3)(urdp)] (3), and cis-[Ru(bpy)2(H4ucp)](PF6)2 (4). Various physicochemical techniques were u...
Source: Journal of Inorganic Biochemistry - March 30, 2024 Category: Biochemistry Authors: Daniel M Makanyane Sanam Maikoo Fanie R Van Heerden Lydia Rhyman Ponnadurai Ramasami Lindokuhle P Mabuza Phikelelani Ngubane Andile Khathi Allen Mambanda Irvin N Booysen Source Type: research
Bovine serum albumin uptake and polypeptide disaggregation studies of hypoglycemic ruthenium(II) uracil Schiff-base complexes
J Inorg Biochem. 2024 Mar 27;255:112541. doi: 10.1016/j.jinorgbio.2024.112541. Online ahead of print.ABSTRACTOur prior studies have illustrated that the uracil ruthenium(II) diimino complex, [Ru(H3ucp)Cl(PPh3)] (1) (H4ucp = 2,6-bis-((6-amino-1,3-dimethyluracilimino)methylene)pyridine) displayed high hypoglycemic effects in diet-induced diabetic rats. To rationalize the anti-diabetic effects of 1, three new derivatives have been prepared, cis-[Ru(bpy)2(urdp)]Cl2 (2) (urdp = 2,6-bis-((uracilimino)methylene)pyridine), trans-[RuCl2(PPh3)(urdp)] (3), and cis-[Ru(bpy)2(H4ucp)](PF6)2 (4). Various physicochemical techniques were u...
Source: Journal of Inorganic Biochemistry - March 30, 2024 Category: Biochemistry Authors: Daniel M Makanyane Sanam Maikoo Fanie R Van Heerden Lydia Rhyman Ponnadurai Ramasami Lindokuhle P Mabuza Phikelelani Ngubane Andile Khathi Allen Mambanda Irvin N Booysen Source Type: research
A randomized comparison of three intubation techniques/tube materials for nasotracheal intubation
CONCLUSIONS: Among the three intubation techniques/tube materials for nasotracheal intubation, the velvet-soft PVC tube provided the highest first-attempt success rate, most expeditious advancement into the oral cavity, and lowest incidence of epistaxis.STUDY REGISTRATION: ClinicalTrials.gov (NCT04695444); first submitted 30 December 2020.PMID:38548948 | DOI:10.1007/s12630-024-02743-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - March 29, 2024 Category: Anesthesiology Authors: Jiwon Lee Jung-Man Lee Yon Hee Shim Joung Goo Cho Jimin Lee Jae-Yol Lim Chul Ho Chang Source Type: research
Mechanistic insight into the impact of interaction between goethite and humic acid on the photooxidation and photoreduction of bifenthrin
Environ Res. 2024 Mar 27:118779. doi: 10.1016/j.envres.2024.118779. Online ahead of print.ABSTRACTNumerous application of pyrethroid insecticides has led to their accumulation in the environment, threatening ecological environment and human health. Its fate in the presence of iron-bearing minerals and natural organic matter under light irradiation is still unknown. We found that goethite (Gt) and humic acid (HA) could improve the photodegradation of bifenthrin (BF) in proper concentration under light irradiation. The interaction between Gt and HA may improve BF degradation. On one hand, the adsorption of HA on Gt may decre...
Source: Environmental Research - March 29, 2024 Category: Environmental Health Authors: Miaomiao Dai Xiaona Dong Yongbo Yang Yuwei Wu Lulu Chen Canlan Jiang Zechong Guo Tongyi Yang Source Type: research
The disrupting effect of chlormequat chloride on growth hormone is associated with pregnancy
Toxicol Lett. 2024 Mar 27;395:17-25. doi: 10.1016/j.toxlet.2024.03.004. Online ahead of print.ABSTRACTSince chlormequat chloride is widely applied as a plant growth regulator in agriculture and horticulture, its exposure through food consumption is common. We demonstrated previously that chlormequat chloride exposure during pregnancy led to embryos with bigger sizes associated with higher levels of growth hormone (GH) on gestation day 11 (GD11). However, the dose-effect relationship of chlormequat chloride at a lower dose range was not established, and the underlying mechanisms of its promoting effects on embryonic growth ...
Source: Toxicology Letters - March 29, 2024 Category: Toxicology Authors: Zongzhen Wu Long Ma Deqi Su Bayindala Xiagedeer Source Type: research
Photo-induced leaching behaviors and biodegradability of dissolved organic matter from microplastics and terrestrial-sourced particles
This study investigates the photo-induced leaching behaviors of dissolved organic matter (DOM) from terrestrial-sourced particles (forest soil and leaf litter) and microplastics (MPs), specifically polystyrene (PS) and polyvinyl chloride (PVC), over a two-week period. We also examined the biodegradability and spectroscopic characteristics of the leached DOM from both sources. Our results reveal that DOM from microplastics (MP-DOM) demonstrates more persistent leaching behavior compared to terrestrial-derived DOM, even with lesser quantities per unit of organic carbon. UV irradiation was found to enhance DOM leaching across...
Source: Chemosphere - March 29, 2024 Category: Chemistry Authors: Na Eun Choi Yun Kyung Lee Haeseong Oh Jin Hur Source Type: research
Multifunctional thiolated chitosan/puerarin composite hydrogels with pH/glutathione dual responsiveness for potential drug carriers
Int J Biol Macromol. 2024 Mar 28:130841. doi: 10.1016/j.ijbiomac.2024.130841. Online ahead of print.ABSTRACTPuerarin (PUE), a natural and biologically active isoflavone extracted from Chinese medicine Pueraria lobata, can self-assemble to form a hydrogel without other chemical modifications. However, although PUE hydrogel has pH responsivity, but it is difficult to adapt to the changeable pathological environment. Therefore, thiolated chitosan (TCS) is synthesized and hybridized with PUE hydrogel to prepare TCS10/PUE composite hydrogel. The results of rheological measurement showed that the resultant composite hydrogels in...
Source: International Journal of Biological Macromolecules - March 29, 2024 Category: Biochemistry Authors: Hao Yuan Zhaoxiang Zeng Dongru Li Rongzeng Huang Wan Li Source Type: research
Photo-induced leaching behaviors and biodegradability of dissolved organic matter from microplastics and terrestrial-sourced particles
This study investigates the photo-induced leaching behaviors of dissolved organic matter (DOM) from terrestrial-sourced particles (forest soil and leaf litter) and microplastics (MPs), specifically polystyrene (PS) and polyvinyl chloride (PVC), over a two-week period. We also examined the biodegradability and spectroscopic characteristics of the leached DOM from both sources. Our results reveal that DOM from microplastics (MP-DOM) demonstrates more persistent leaching behavior compared to terrestrial-derived DOM, even with lesser quantities per unit of organic carbon. UV irradiation was found to enhance DOM leaching across...
Source: Chemosphere - March 29, 2024 Category: Chemistry Authors: Na Eun Choi Yun Kyung Lee Haeseong Oh Jin Hur Source Type: research
Nickel induces mitochondrial damage in renal cells in vitro and in vivo through its effects on mitochondrial biogenesis, fusion, and fission
This study provided novel insights into the mechanisms of nephrotoxicity of Ni and new ideas for the development of targeted treatments for Ni-induced kidney injury.PMID:38552765 | DOI:10.1016/j.cbi.2024.110975 (Source: Chemico-Biological Interactions)
Source: Chemico-Biological Interactions - March 29, 2024 Category: Molecular Biology Authors: Heng Yin Xinglai Li Chengbi Wang Xiaocong Li Jingbo Liu Source Type: research
A randomized comparison of three intubation techniques/tube materials for nasotracheal intubation
CONCLUSIONS: Among the three intubation techniques/tube materials for nasotracheal intubation, the velvet-soft PVC tube provided the highest first-attempt success rate, most expeditious advancement into the oral cavity, and lowest incidence of epistaxis.STUDY REGISTRATION: ClinicalTrials.gov (NCT04695444); first submitted 30 December 2020.PMID:38548948 | DOI:10.1007/s12630-024-02743-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - March 29, 2024 Category: Anesthesiology Authors: Jiwon Lee Jung-Man Lee Yon Hee Shim Joung Goo Cho Jimin Lee Jae-Yol Lim Chul Ho Chang Source Type: research
A randomized comparison of three intubation techniques/tube materials for nasotracheal intubation
CONCLUSIONS: Among the three intubation techniques/tube materials for nasotracheal intubation, the velvet-soft PVC tube provided the highest first-attempt success rate, most expeditious advancement into the oral cavity, and lowest incidence of epistaxis.STUDY REGISTRATION: ClinicalTrials.gov (NCT04695444); first submitted 30 December 2020.PMID:38548948 | DOI:10.1007/s12630-024-02743-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - March 29, 2024 Category: Anesthesiology Authors: Jiwon Lee Jung-Man Lee Yon Hee Shim Joung Goo Cho Jimin Lee Jae-Yol Lim Chul Ho Chang Source Type: research
A randomized comparison of three intubation techniques/tube materials for nasotracheal intubation
CONCLUSIONS: Among the three intubation techniques/tube materials for nasotracheal intubation, the velvet-soft PVC tube provided the highest first-attempt success rate, most expeditious advancement into the oral cavity, and lowest incidence of epistaxis.STUDY REGISTRATION: ClinicalTrials.gov (NCT04695444); first submitted 30 December 2020.PMID:38548948 | DOI:10.1007/s12630-024-02743-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - March 29, 2024 Category: Anesthesiology Authors: Jiwon Lee Jung-Man Lee Yon Hee Shim Joung Goo Cho Jimin Lee Jae-Yol Lim Chul Ho Chang Source Type: research
