Near-atomic 'maps' reveal structure for maintaining pH balance in cells
(Van Andel Research Institute) For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other brain injuries. These gates, called proton-activated chloride channels (PAC), nest within cell membranes and regulate the passage of small molecules called chloride ions into and out of cells. This allows cells to sense and respond to their environment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 4, 2020 Category: International Medicine & Public Health Source Type: news

Granules India gets USFDA nod for potassium chloride tablets used to treat hypokalemia
Granules has received marketing approval from the US Food and Drug Administration (USFDA) for Potassium Chloride extended release tablets USP in the strengths of 10 mEq (750 mg) and 20 mEq (1500 mg), the company said in a BSE filing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 22, 2020 Category: Pharmaceuticals Source Type: news

Urecholine (Bethanechol Chloride Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 21, 2020 Category: Drugs & Pharmacology Source Type: news

FDA Warns Companies About Illegal Sales of Dietary Supplements
The supplements contain cesium chloride, but no cesium chloride - containing products are FDA - approved (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - October 15, 2020 Category: Cancer & Oncology Tags: Endocrinology, Family Medicine, Internal Medicine, Nursing, Oncology, Pharmacy, Institutional, Source Type: news

FDA Warns Companies About Illegal Sales of Dietary Supplements
WEDNESDAY, Oct. 14, 2020 -- Warning letters have been sent to five companies for illegally selling dietary supplements that contain cesium chloride, the U.S. Food and Drug Administration said Tuesday. Earlier this year, the agency warned consumers... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 14, 2020 Category: Pharmaceuticals Source Type: news

Complete recovery following "Veeram" (Mercury II chloride) poisoning: a case report - Sathiaruban S, Ghetheswaran S, Weerakkody RM.
We describe a case with acute, suicidal, mercury (II) chloride poisoning, who presented with confusion, acidosis and renal shut down. He was managed with mercury c... (Source: SafetyLit)
Source: SafetyLit - October 14, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

The Mineral Store, Inc./Elemental Research, Inc. - 609178 - 10/09/2020
Dietary Supplement/Adulterated/Cesium Chloride (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 13, 2020 Category: Drugs & Pharmacology Authors: Center for Food Safety and Applied Nutrition Source Type: news

Daily Manufacturing Company - 609000 - 10/09/2020
Dietary Supplement/Adulterated/Cesium Chloride (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 13, 2020 Category: Drugs & Pharmacology Authors: Center for Food Safety and Applied Nutrition Source Type: news

Complete H2O Minerals Corporation - 608999 - 10/09/2020
Dietary Supplement/Adulterated/Cesium Chloride (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 13, 2020 Category: Drugs & Pharmacology Authors: Center for Food Safety and Applied Nutrition Source Type: news

Zydus Cadila gets American health regulator's approval to market mineral supplement
Zydus Cadila has received final approval from the US Food and Drug Administration (USFDA) to market Potassium Chloride extended release tablets in the strengths of 10 mEq (750 mg) and 20 mEq (1,500 mg), Zydus Cadila, part of Cadila Healthcare group. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 17, 2020 Category: Pharmaceuticals Source Type: news

Association between acute severe mercury poisoning and multiple organ failure - Bai L, Peng X, Liu Y, Sun Y, Zheng L, Liu Z, Wan K, Wang J, Zhao J, Qiu Z.
Acute mercury poisoning, involving a number of organs, leads to severe dysfunctions, such as acute renal failure (ARF), and even threatens patients' lives. A case of acute severe mercuric chloride (HgCl2) poisoning with multiple organ failure was reported ... (Source: SafetyLit)
Source: SafetyLit - September 16, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

The role of endoplasmic reticulum stress in renal damage caused by acute mercury chloride poisoning - Zhong Y, Wang B, Hu S, Wang T, Zhang Y, Wang J, Liu Y, Zhang H.
Acute mercury chloride (HgCl2) poisoning may lead to kidney injury, but the underlying mechanism remains largely unknown. Endoplasmic reticulum (ER) stress plays a role in some heavy metal poisoning. Whether it mediates kidney injury in acute HgCl2 poisoni... (Source: SafetyLit)
Source: SafetyLit - September 7, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Normal Saline (Sodium Chloride Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 12, 2020 Category: Drugs & Pharmacology Source Type: news

ATNAA (Atropine and Pralidoxime Chloride Injection ) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 23, 2020 Category: Drugs & Pharmacology Source Type: news

Fresenius Kabi Issues Voluntary Nationwide Recall of Two Lots of Dexmedetomidine Hydrochloride Injection Due to Cross-Contamination of Lidocaine
Fresenius Kabi USA is voluntarily recalling two lots of Dexmedetomidine HCl in 0.9% Sodium Chloride Injection, 200 mcg/50 mL (4 mcg / mL), 50 mL fill in a 50 mL vial. Fresenius Kabi initiated this recall due to the possibility of a trace amount of lidocaine present in these two lots and our investig (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 22, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news