Dyna-Hex 2 (Chlorhexidine Gluconate Liquid) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 7, 2019 Category: Drugs & Pharmacology Source Type: news

Results of ABATE infection trial published
(Harvard Pilgrim Health Care Institute) Daily bathing with an antiseptic soap, plus nasal ointment for patients with prior antibiotic resistant bacteria, reduced hospital acquired infections among patients with central venous catheters and other devices that pierce the skin, according to results of the ABATE Infection Trial. The study, " Chlorhexidine versus Routine Bathing to Prevent Multi Drug-Resistant Organisms and All-Cause Bloodstream Infection in General Medical and Surgical Units: The ABATE Infection Cluster Randomized Trial, " was published March 5 in The Lancet, Online. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 5, 2019 Category: Infectious Diseases Source Type: news

Results of trial to stem hospital-acquired bacterial infections published
(NIH/National Institute of Allergy and Infectious Diseases) A trial evaluated whether daily bathing with the antiseptic soap chlorhexidine (CHG) -- and in those patients with MRSA, adding the nasal antibiotic mupirocin -- more effectively reduced hospital-acquired bacterial infections than bathing with ordinary soap and water. The researchers found that one subset of patients -- those with medical devices -- experienced a substantial benefit if they received the CHG/mupirocin intervention. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 5, 2019 Category: Infectious Diseases Source Type: news

World Oral Health Day
is celebrated globally every year on 20 March. It helps to spread messages about good oral hygiene practices and demonstrates the importance of optimal oral health in maintaining general health and well-being. It ' s an excellent time to put the spotlight on related Cochrane evidence.Cochrane Oral Healthpublishes systematic reviews of the best quality research available to help patients, carers, clinicians, researchers, and funders make better informed decisions about oral healthcare choices. Cochrane Oral Health ' s  work is carried out by over 1600 members, with over 900 authors from more than 40 different countries.Wh...
Source: Cochrane News and Events - February 20, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Postdischarge Decolonization Plan Lowers MRSA Risk (CME/CE)
(MedPage Today) -- At-home protocol involved chlorhexidine mouthwash, chlorhexidine baths or showers, and nasal mupirocin (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 20, 2019 Category: American Health Source Type: news

Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
This RCT (n=2121) found postdischarge hygiene education (HE) and MRSA decolonisation with chlorhexidine and mupirocin led to lower risk of MRSA infection than HE alone (HR 0.70;95% CI 0.52-0.96;p=0.03) which led to lower risk of hospitalisation due to MRSA infection (0.71; 0.51-0.99). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news

NIHR Signal: Decontamination of the mouth or digestive tract was not linked to reductions in drug-resistant bloodstream infections in the intensive care unit
This expert commentary is provided for an RCT (n=8,665) which found that decontamination strategies with either antibiotics or chlorhexidine mouthwash did not reduce bloodstream infections. This evidence suggests that widespread adoption of decontamination techniques is not justified. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news

Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
This research article concludes that postdischarge MRSA decolonization with chlorhexidine and mupirocin led to a 30% lower risk of MRSA infection than education alone. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news

In vivo antimicrobial activity of silver diammine fluoride on carious lesions in dentin.
J Oral Sci. 2019 Feb 6. doi: 10.2334/josnusd.17-0366. [Epub ahead of print]AbstractMinimally invasive treatment protocols may leave a residual layer of carious dentin, which requires treatment for the inhibition of bacterial growth beneath restorations. We aimed to examine the in vivo effect of silver diammine fluoride (SDF) and SDF + potassium iodide (KI) application on bacteria present in deep carious lesions. We studied the in vivo efficacy in five patients, each of which had five carious lesions. Dentin samples taken before and after treatment were subjected to microbial analyses. Following treatment with SDF, the medi...
Source: Dental Technology Blog - February 12, 2019 Category: Dentistry Source Type: news

Effectiveness of Different Commercial Chlorhexidine-Based Mouthwashes After Periodontal and Implant Surgery A Systematic Review
Conclusion: Chlorhexidine is recognized as the primary agent forplaque control and the gold standard in preventing infection, although the presence of largely known side effects would affect patient compliance. Future research should be directed at finding chlorhexidine formulation with negligible adverse effects, without compromising or even increasing its effectiveness as the antiseptics and antiplaque agent. (Source: Dental Technology Blog)
Source: Dental Technology Blog - January 31, 2019 Category: Dentistry Source Type: news

Periogard (Chlorhexidine Gluconate Oral Rinse) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 31, 2019 Category: Drugs & Pharmacology Source Type: news

Nonsurgical Treatment of Peri-implantitis Without Eliminating Granulation Tissue A 3-Year Study
Conclusion: Nonsurgical implantdebridement alone seemed not efficient in the treatment of peri-implantitis. Further longitudinal studies are required to evaluate the efficacy of mechanicaldebridement with chemical detoxification and removal of granulation tissues against mechanicaldebridement with chemical detoxification alone. (Source: Dental Technology Blog)
Source: Dental Technology Blog - January 30, 2019 Category: Dentistry Source Type: news

Efficacy of chlorhexidine rinses after periodontal or implant surgery: a systematic review
ConclusionChlorhexidine rinsing helps to reduce biofilm formation and gingival inflammation after surgery. However, no additional reduction of periodontal probing depth over any given placebo or control solution could be found irrespective of whether CHX was used or not. The use of additives such as antidiscoloration systems (ADS) or herbal extracts may reduce side effects while retaining efficacy.Clinical relevanceWithin the limitations of this review, it can be concluded that CHX may represent a valuable chemo-preventive tool immediately after surgery, during the time period in which oral hygiene capacity is compromised....
Source: Dental Technology Blog - January 4, 2019 Category: Dentistry Source Type: news

Routine dental care: does the evidence give us something to smile about?
In thisEvidently Cochrane blog, Sarah Chapman looks at the Cochrane evidence for aspects of routine dental care. Something to smile about? Or are there big gaps …?“Are you afraid to laugh?” Goodall’s Dental Institute, 1912.Wellcome Collection.My grandmother used to tell the tale of when she was a schoolgirl, back in about 1920, and a school event to which parents were invited. Nan and her friend enjoyed a carefree afternoon without their mothers there, having avoided inviting them – the friend because her mother had white hair, and Nan because her mother had just had all her teeth taken out. There was trouble, sh...
Source: Cochrane News and Events - November 29, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Prophylactic Antibiotics Ineffective Against Bloodstream Infections in ICUs Prophylactic Antibiotics Ineffective Against Bloodstream Infections in ICUs
In ventilated intensive care unit (ICU) patients, neither chlorhexidine (CHX) mouthwash nor selective oropharyngeal decontamination (SOD) nor selective digestive tract decontamination (SDD) seems to significantly reduce multidrug-resistant gram-negative bacteria (MDRGNB)-induced bloodstream infections in settings with moderate to high antibiotic resistance, researchers say.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - November 1, 2018 Category: Intensive Care Tags: Critical Care News Source Type: news