Govt taking steps to reduce country's dependence on imports of antibiotic raw materials
As per the information received from the port offices of the Central Drugs Standard Control Organisation (CDSCO), it stood at 12,006.11 metric tonne (MT) for 2018 and 5,591.44 MT in 2017, Minister of Chemicals& Fertilizers D V Sadananda Gowda said. In this direction, the government has withdrawn exemption of customs duty on certain categories of bulk drugs/ APIs. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 11, 2020 Category: Pharmaceuticals Source Type: news

Oleander and datura poisoning: an update - Pillay VV, Sasidharan A.
India has a very high incidence of poisoning. While most cases are due to chemicals or drugs or envenomation by venomous creatures, a significant proportion also results from consumption or exposure to toxic plants or plant parts or products. The exact nat... (Source: SafetyLit)
Source: SafetyLit - February 10, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

NIH scientists link higher maternal blood pressure to placental gene changes
(NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development) Higher maternal blood pressure in pregnancy is associated with chemical modifications to placental genes, according to a study by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2020 Category: International Medicine & Public Health Source Type: news

CCNY chemists develop safer hydrogenation processes
(City College of New York) Safe and environmentally-friendly hydrogen gas on demand could be on the horizon following a new 'hydrogenation' chemical process in development at The City College of New York. Led by Mahesh K. Lakshman, the research uniquely bypasses the need for an external source of hydrogen gas to accomplish a wide range of hydrogenations. It appears as an inside cover feature in the 2020 issue #1 of journal 'Advanced Synthesis and Catalysis.' (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2020 Category: International Medicine & Public Health Source Type: news

Chemistry technique is 'warp drive' for creating better synthetic molecules for medicine
(Scripps Research Institute) In a study with implications for the future of drug discovery, Scripps Research scientists showed they were able to turn simple chemicals into unique 3-D structures resembling those found in nature -- structures with desirable properties for medicines. In the process, they found a potential drug lead for inflammatory disease, which is now being investigated further. The research appears in Nature Chemistry. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 10, 2020 Category: International Medicine & Public Health Source Type: news

JB Chemicals Gujarat unit passes USFDA inspection with one observation
This observation does not impact continuity of the business and the company would continue its manufacturing activities in current good manufacturing practice (cGMP) compliant manner, JB Chemicals and Pharmaceuticals said . The company proposes to address this observation in the next 15 days. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - February 10, 2020 Category: Pharmaceuticals Source Type: news

DR MICHAEL MOSLEY: Could magic mushrooms be the new Prozac?
A chemical called psilocybin, originally found in magic mushrooms, is being hailed as a potential lifesaver for people with depression. So is the hype justified, asks DR MICHAEL MOSLEY. (Source: the Mail online | Health)
Source: the Mail online | Health - February 8, 2020 Category: Consumer Health News Source Type: news

Exposure research bolstered by new NIEHS resource
Scientists studying how chemical, biological, and social stressors affect human health will gain access to state-of-the-art research tools. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 8, 2020 Category: Environmental Health Source Type: news

Avoiding Endocrine-Disrupting Chemicals: 5 Tips Avoiding Endocrine-Disrupting Chemicals: 5 Tips
When it comes to endocrine-disrupting chemicals, Dr Leonardo Trasande disagrees with the idea of consuming'everything in moderation .'Here are 5 simple tips to help avoid exposure to these chemicals.Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 7, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Article Source Type: news

Side effect of long commutes: Car seat carcinogens
California study finds people with longer commutes face higher exposure to cancerous chemicals from car seats. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 7, 2020 Category: Consumer Health News Source Type: news

Preventing, healing tooth decay with a bioactive peptide
American Chemical Society Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful, but untreated caries could lead to worse pain, tooth loss, infection, and even illness or death. Now, researchers inACS Applied Materials& Interfaces report a bioactive peptide that coats tooth surfaces, helping prevent new cavities and heal existing ones in lab experiments.Conventional treatment for dental cavities involves removing decayed tissue and filling the hole with materials, su...
Source: Dental Technology Blog - February 7, 2020 Category: Dentistry Source Type: news

Africa: Addressing Hazardous Waste Within Africa
[UNEP] In mid-February, government representatives from across the African continent will come together in Brazzaville, Republic of the Congo to work towards a safe chemicals and waste future. Read on for more about the process and what it means. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 7, 2020 Category: African Health Source Type: news

New commuter concern: Cancerous chemical in car seats
(University of California - Riverside) The longer your commute, the more you're exposed to a chemical flame retardant that is a known carcinogen and was phased out of furniture use because it required a Proposition 65 warning label in California. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2020 Category: International Medicine & Public Health Source Type: news

New details on how a viral protein puts the brakes on virus replication
(Colorado State University) Researchers used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 7, 2020 Category: Infectious Diseases Source Type: news

George Mason receives NIH grant to study environmental pollutants and endometriosis links
(George Mason University) George Mason University College of Health and Human Services has received a $1.6M grant from the National Institute of Environmental Health Sciences (NIEHS) to study the link between endometriosis and endocrine disrupting chemicals. The study seeks to answer two questions: first whether levels of these endocrine disruptors inside the uterus are associated with endometriosis and, second, if these chemicals in endometrial tissue found outside the uterus are associated with the severity of the disorder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2020 Category: International Medicine & Public Health Source Type: news

High levels of PFAS affect immune, liver functions in cape fear river striped bass
(North Carolina State University) Researchers have found elevated levels of 11 per- and polyfluoroalkyl (PFAS) chemicals in the blood of Cape Fear River striped bass. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2020 Category: International Medicine & Public Health Source Type: news

Cold plasma patch could make immunotherapy more effective for treating melanoma, study finds
This study represents an important milestone for the field of plasma medicine,” said co-senior author Richard Wirz, professor of mechanical and aerospace engineering at UCLA Samueli. “It demonstrates that the microneedle patch can realize the plasma delivery while also working with the drug t o improve the effectiveness of cancer therapy.”“Plasma can generate reactive oxygen species and reactive nitrogen species, which are a group of chemical species that can destroy cancer cells,” said Guojun Chen, who is the co-first author of the study and a postdoctoral fellow in Gu’s laboratory.&ldq...
Source: UCLA Newsroom: Health Sciences - February 6, 2020 Category: Universities & Medical Training Source Type: news

Ten U.S. refineries emitted excessive cancer-causing benzene in 2019: report
Ten U.S. oil refineries, including six in Texas, released the cancer-causing chemical benzene in concentrations that exceeded federal limits last year, according to government data published by the green group Environmental Integrity Project on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - February 6, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Some U.S. Workers Are Bringing Toxins Home to Their Kids
THURSDAY, Feb. 6, 2020 -- People who work with potentially dangerous chemicals or hazardous metals such as lead may unwittingly bring those toxic substances home, a new review says. In the home, these substances put family members, especially... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 6, 2020 Category: General Medicine Source Type: news

Corteva to stop making pesticide linked to kids' health problems
Corteva Inc will stop producing the agricultural pesticide chlorpyrifos by the end of the year, the company said on Thursday, removing the world's largest manufacturer of a chemical that has been linked to low birth weight, reduced IQ and attention disorders in children. (Source: Reuters: Health)
Source: Reuters: Health - February 6, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Chemical found in drinking water linked to tooth decay in children
(West Virginia University) Children with higher concentrations of a certain chemical in their blood are more likely to get cavities, according to a new study by West Virginia University School of Dentistry researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 6, 2020 Category: International Medicine & Public Health Source Type: news

Scientists reveal whole new world of chemistry by stepping indoors
(Colorado State University) Delphine Farmer and her team at Colorado State University have published their first major study, about bleach cleaning, from HOMEChem, a collaborative experiment with 13 universities that mapped the airborne chemistry of a typical home. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 6, 2020 Category: Biology Source Type: news

AOCS Research Awards go to five UMass Amherst food science Ph.D. students
(University of Massachusetts Amherst) Five food science Ph.D. students at the University of Massachusetts Amherst have been honored with 2020 student awards from the American Oil Chemists' Society (AOCS) for their outstanding contributions to science. The AOCS is a century-old international scientific and professional organization serving the field of fats, oils and lipids. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 6, 2020 Category: International Medicine & Public Health Source Type: news

Scientists create 'Chemical gardens' that can be used as bone substitute materials
(University of Birmingham) A new way of making bone-replacement materials that allows for cells to grow around and inside them has been developed by researchers at the University of Birmingham. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 6, 2020 Category: International Medicine & Public Health Source Type: news

Prosecutor details China probe that snared chemist
(Source: ScienceNOW)
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Mervis, J. Tags: Scientific Community, Science and Policy In Depth Source Type: news

Synthesis of Taxol's complicated cousin
(Source: ScienceNOW)
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Yeston, J. Tags: Chemistry twis Source Type: news

Major-league magnetostriction
(Source: ScienceNOW)
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Grocholski, B. Tags: Chemistry, Materials Science twis Source Type: news

Graceful choreography for CO2 and H2O
(Source: ScienceNOW)
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Yeston, J. Tags: Chemistry twis Source Type: news

CO2 electrolysis to multicarbon products at activities greater than 1 A cm-2
Electrolysis offers an attractive route to upgrade greenhouse gases such as carbon dioxide (CO2) to valuable fuels and feedstocks; however, productivity is often limited by gas diffusion through a liquid electrolyte to the surface of the catalyst. Here, we present a catalyst:ionomer bulk heterojunction (CIBH) architecture that decouples gas, ion, and electron transport. The CIBH comprises a metal and a superfine ionomer layer with hydrophobic and hydrophilic functionalities that extend gas and ion transport from tens of nanometers to the micrometer scale. By applying this design strategy, we achieved CO2 electroreduction o...
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Garcia de Arquer, F. P., Dinh, C.-T., Ozden, A., Wicks, J., McCallum, C., Kirmani, A. R., Nam, D.-H., Gabardo, C., Seifitokaldani, A., Wang, X., Li, Y. C., Li, F., Edwards, J., Richter, L. J., Thorpe, S. J., Sinton, D., Sargent, E. H. Tags: Chemistry reports Source Type: news

Room temperature magnetoelectric coupling in a molecular ferroelectric ytterbium(III) complex
Magnetoelectric (ME) materials combine magnetic and electric polarizabilities in the same phase, offering a basis for developing high-density data storage and spintronic or low-consumption devices owing to the possibility of triggering one property with the other. Such applications require strong interaction between the constitutive properties, a criterion that is rarely met in classical inorganic ME materials at room temperature. We provide evidence of a strong ME coupling in a paramagnetic ferroelectric lanthanide coordination complex with magnetostrictive phenomenon. The properties of this molecular material suggest tha...
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Long, J., Ivanov, M. S., Khomchenko, V. A., Mamontova, E., Thibaud, J.-M., Rouquette, J., Beaudhuin, M., Granier, D., Ferreira, R. A. S., Carlos, L. D., Donnadieu, B., Henriques, M. S. C., Paixao, J. A., Guari, Y., Larionova, J. Tags: Chemistry, Materials Science reports Source Type: news

Total synthesis of the complex taxane diterpene canataxpropellane
Canataxpropellane belongs to the medicinally important taxane diterpene family. The most prominent congener, Taxol, is one of the most commonly used anticancer agent in clinics today. Canataxpropellane exhibits a taxane skeleton with three additional transannular C–C bonds, resulting in a total of six contiguous quaternary carbons, of which four are located on a cyclobutane ring. Unfortunately, isolation of canataxpropellane from natural sources is inefficient. Here, we report a total synthesis of (–)-canataxpropellane in 26 steps and 0.5% overall yield from a known intermediate corresponding to 29 steps from c...
Source: ScienceNOW - February 6, 2020 Category: Science Authors: Schneider, F., Samarin, K., Zanella, S., Gaich, T. Tags: Chemistry reports Source Type: news

The metric system: arguments for and against – archive, 5 February 1910
5 February 1910: A debate held last night allowed both sides to put forward their views on this contentious subjectSome of the arguments for and against the substitution of the metric system for the system of weights and measures now in use in this country were summed up at a debate held by the Manchester Society of Chemical Industry last night. Mr J Hoseason was in the chair.Related:Metric v imperial: what's best in schools?Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - February 5, 2020 Category: Science Tags: Science Shops and shopping Source Type: news

Improving adhesives for wearable sensors
(American Chemical Society) By conveniently and painlessly collecting data, wearable sensors create many new possibilities for keeping tabs on the body. In order to work, these devices need to stay next to the skin. In a study described in ACS Omega, researchers tweaked a widely used polymer to create a potential new adhesive to keep these sensors in place.   (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2020 Category: International Medicine & Public Health Source Type: news

Re-engineered plant compound treats opioid addiction in mice
(American Chemical Society) The abuse of prescription and illegal opioids, such as morphine and heroin, is a major problem in the US, with devastating public health, economic and social consequences. That's why scientists are searching for new medicines to help break the cycle of addiction. Now, researchers reporting in ACS' Journal of Medicinal Chemistry have re-engineered the structure of vincamine, a plant-derived compound, so that it reduces morphine-seeking behaviors in mice.   (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2020 Category: International Medicine & Public Health Source Type: news

Researchers brighten path for creating new type of MRI contrast agent
(University of Texas at Dallas) University of Texas at Dallas researchers are breathing new life into an old MRI contrast agent by attaching it to a plant virus and wrapping it in a protective chemical cage. The novel strategy is aimed at developing a completely organic and biodegradable compound that would eliminate the need to use heavy metals such as gadolinium in contrast agents. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2020 Category: International Medicine & Public Health Source Type: news

High-precision imaging revealed what holds on the smallest light responsive gold chain
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) Manufacture of chemical sensors and catalysts based on gold nanoclusters gained new light from recent cutting-edge research. Chemists at the University of Jyv ä skyl ä , Finland and the University of California succeeded in determining the atomic precise structure of a chain of gold nanoclusters attached to each other. The researchers revealed the disulfide-bridging bond between the bound nanoclusters. Linked gold nanocluster structures advance our understanding of the optical and electronic response of these systems which hold future per...
Source: EurekAlert! - Biology - February 5, 2020 Category: Biology Source Type: news

Introduction to safenology and its application to the safety management of chemicals - Kitano M.
[in Japanese] Language: ja... (Source: SafetyLit)
Source: SafetyLit - February 4, 2020 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news

Chemical found in lemon peel may reset disrupted circadian clock
The increased risk of metabolic disease caused by disruptions to the cellular circadian clock may be reduced using a chemical in lemon peel, according to a study published in theProceedings of the National Academy of Sciences.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 4, 2020 Category: Endocrinology Source Type: news

Scientists find cigarette butt chemicals could be nearly as harmful as smoking
Scientists from the US National Institute of Standards and Technology, Maryland, found a 'significant' level of nicotine emitted from extinguished cigarettes for days. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2020 Category: Consumer Health News Source Type: news

Chemistry for Toxicological Risk Assessment —Transitions in Expected Approach
One of the cornerstones of biocompatibility evaluations is the use of toxicological risk assessment to screen for potential hazards and safeguard against long-onset risks like cancer. While there is an abundance of toxicological literature available, and the techniques of toxicological risk assessment are generally accepted, the process for conducting the underlying chemistry studies is less mature. FDA has been building finesse in reviewing chemistry studies, helping the testing facilities to be more aware of the nuances in chemistry. New internal awareness and recent reports with poorly conducted studies used for regulat...
Source: MDDI - February 4, 2020 Category: Medical Devices Authors: Matthew Jorgensen Tags: Testing Source Type: news

Synthetic mushroom toxin
(Wiley) The death cap mushroom is highly toxic. However, some of its toxins can also be healing: amanitins are potential components for antibody-based cancer treatments. In the journal Angewandte Chemie, German scientists have now introduced a new synthetic route for alpha-amanitin. Their method seems suitable for production on a larger scale, finally making enough of the toxin available for further research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 4, 2020 Category: Cancer & Oncology Source Type: news

Stem cell research studying heart growth earns Syracuse engineer NSF CAREER award
(Syracuse University) Syracuse University biomedical and chemical engineering Professor Zhen Ma has received a National Science Foundation (NSF) CAREER Award for his project entitled 'Engineering Stem Cell-Based Cardiac Organoids.' Ma's research centers on using stem cells to study the formation and growth of a heart during embryo development. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 4, 2020 Category: Biology Source Type: news

Research Security: Scientists Arrested as Government Increases Efforts to Protect US Security Interests
Concerns about and oversight of foreign influence on research and espionage have been rising since 2018. In an August 2018 letter to more than 10,000 research institutions, NIH urged grant applicants and awardees to properly disclose all forms of support and financial interests and launched investigations into NIH-funded investigators who failed to properly disclose foreign financial support. Following this, an April 2019 editorial in BioScience alerted readers that investigations into foreign ties of researchers will likely spread to other agencies and need to be taken seriously. Lawmakers have also made enquiries about t...
Source: Public Policy Reports - February 4, 2020 Category: Biology Authors: AIBS Source Type: news

Prenatal environment may influence brain disorders later in life
Alan Brown’s research links infections, chemical exposures, and inflammation in pregnancy to offspring’s schizophrenia, autism, and more. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2020 Category: Environmental Health Source Type: news

Exposure research bolstered by new NIEHS resource
Scientists studying how chemical, biological, and social stressors affect human health will gain access to state-of-the-art research tools. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2020 Category: Environmental Health Source Type: news

Replacement chemicals may put pregnancies at risk
Newer chemicals, which replace those phased out decades ago, may have harmful effects on pregnancy, says Liping Feng. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2020 Category: Environmental Health Source Type: news

How to stop the dying, as well as the killing, in a terrorist attack - Park CL, Langlois M, Smith ER, Pepper M, Christian MD, Davies GE, Grier GR.
Mobile attackers with bladed weapons, firearms, or explosive devices are currently a significant global threat to the public and emergency responders. The risk of chemicals, vehicles, and fire used as weapons adds further complexity to such attacks. ... (Source: SafetyLit)
Source: SafetyLit - February 3, 2020 Category: International Medicine & Public Health Tags: Commentary Source Type: news

Scientists discover a 'chemical ear muff' drug that could protect hearing
Scientists at Iowa University and the University of Washington, St Louis, created a chemical compound that blocked receptors responsible for auditory neuron damage in mice. (Source: the Mail online | Health)
Source: the Mail online | Health - February 3, 2020 Category: Consumer Health News Source Type: news

Janssen to Highlight Depth of Solid Tumor Portfolio at ASCO GU
RARITAN, N.J., February 3, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today multiple data presentations from a robust solid tumor portfolio that will be featured at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco. Company-sponsored data presentations will include clinical results for ERLEADA® (apalutamide) and niraparib in prostate cancer; and BALVERSA™ (erdafitinib) in bladder cancer. “We are committed to improving outcomes in patients with prostate and bladder cancer where high unmet...
Source: Johnson and Johnson - February 3, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news