Coronavirus kits to be sold only on doctors' prescription: FDA
In an order issued on Thursday, FDA commissioner Arun Unhale said the Maharashtra government and FDA had received several complaints of chemists selling PPE kits and N-95 masks at prices higher than the MRP. The FDA has also directed chemists to sell PPE kits and masks only on doctors' prescription, a spokesman of the FDA's Konkan division said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 6, 2020 Category: Pharmaceuticals Source Type: news

P & G tweaks formula of premium-tier toothpaste
Procter& Gamble Co. has reformulated its Native brand toothpaste as a result of customer feedback. The Cincinnati-based maker of consumer goods (NYSE: PG) launched Native toothpaste in December 2018, which was just over a year after P&G acquired the startup that specializes in premium-tier personal care products that are devoid of what some people consider to be harmful chemicals. “Native’s 2.0 version includes new and longer lasting toothpaste flavors, new packaging, more foam, better whitening… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 5, 2020 Category: Pharmaceuticals Authors: Barrett J. Brunsman Source Type: news

Country diary: jelly ears on rotting wood listen out for rain
Wenlock Edge, Shropshire: Also known as wood ear, this brown fungus is waiting to release thousands of sporesThere is something uncannily alien about living jelly. Lobes of brown, gelatinous fungus growing out of dead and fallen branches are jelly ear,Auricularia auricula-judae. Once called the Judas ’s ear fungus because it often grows on the elder, the tree Judas Iscariot was supposed to have hanged himself on, it was mistranslated in the casual racism of 16th-century English as Jew’s ear.Also known aswood ear, it has an orangey brown to a deep chocolatey colour. It is edible (not tried it yet) and, as the &l...
Source: Guardian Unlimited Science - March 5, 2020 Category: Science Authors: Paul Evans Tags: Fungi Plants Environment Rivers Biology Science Source Type: news

Humans transport dangerous smoke residues indoors
(Max Planck Institute for Chemistry) A team of scientists discovered that people carry hazardous compounds from cigarette smoke into non-smoking environments. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 5, 2020 Category: International Medicine & Public Health Source Type: news

MacMillan illuminates the micro-environment, creating a new path to cancer drugs
(Princeton University) A team of Princeton chemists has identified a way to tag a protein's nearest molecular neighbors, enabling the precise mapping of their micro-environment. This could open new avenues to cancer treatment and other drug therapies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 5, 2020 Category: International Medicine & Public Health Source Type: news

It's not just secondhand smoke that is dangerous. Thirdhand smoke can be, too
You could be exposed to dangerous chemicals from tobacco via thirdhand smoke, which comes from the bodies or clothing of smokers even if they are not actively smoking, a new study says. (Source: CNN.com - Health)
Source: CNN.com - Health - March 5, 2020 Category: Consumer Health News Source Type: news

Smokers 'contaminate public places' with their CLOTHES
In the first study of its kind, researchers from Yale University, New Haven, Connecticut, traced chemicals in a cinema. Toxins soared during films for adults, where smokers were present. (Source: the Mail online | Health)
Source: the Mail online | Health - March 5, 2020 Category: Consumer Health News Source Type: news

Pinpointing proteins
(Source: ScienceNOW)
Source: ScienceNOW - March 5, 2020 Category: Science Authors: Yeston, J. Tags: Biochemistry, Chemistry twis Source Type: news

Microenvironment mapping via Dexter energy transfer on immune cells
Many disease pathologies can be understood through the elucidation of localized biomolecular networks, or microenvironments. To this end, enzymatic proximity labeling platforms are broadly applied for mapping the wider spatial relationships in subcellular architectures. However, technologies that can map microenvironments with higher precision have long been sought. Here, we describe a microenvironment-mapping platform that exploits photocatalytic carbene generation to selectively identify protein-protein interactions on cell membranes, an approach we term MicroMap (μMap). By using a photocatalyst-antibody conjugate to ...
Source: ScienceNOW - March 5, 2020 Category: Science Authors: Geri, J. B., Oakley, J. V., Reyes-Robles, T., Wang, T., McCarver, S. J., White, C. H., Rodriguez-Rivera, F. P., Parker, D. L., Hett, E. C., Fadeyi, O. O., Oslund, R. C., MacMillan, D. W. C. Tags: Biochemistry, Chemistry r-articles Source Type: news

Single-atom vibrational spectroscopy in the scanning transmission electron microscope
Single-atom impurities and other atomic-scale defects can notably alter the local vibrational responses of solids and, ultimately, their macroscopic properties. Using high-resolution electron energy-loss spectroscopy in the electron microscope, we show that a single substitutional silicon impurity in graphene induces a characteristic, localized modification of the vibrational response. Extensive ab initio calculations reveal that the measured spectroscopic signature arises from defect-induced pseudo-localized phonon modes—that is, resonant states resulting from the hybridization of the defect modes and the bulk conti...
Source: ScienceNOW - March 5, 2020 Category: Science Authors: Hage, F. S., Radtke, G., Kepaptsoglou, D. M., Lazzeri, M., Ramasse, Q. M. Tags: Materials Science, Physics reports Source Type: news

Third-hand smoke is no joke, can convey hazardous chemicals
People can carry hazardous compounds from cigarette smoke that cling to their bodies and then release them into non-smoking environments, a Yale study finds. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 4, 2020 Category: Universities & Medical Training Source Type: news

'Thirdhand' smoke a health risk in cinemas, say researchers
Hazardous chemicals could be carried on clothing and bodies of audience, study suggestsThe lights dim, the trailers roll and the mutter of voices dwindles to a hush. But alongside the smell of popcorn, another scent pervades the cinema: the waft of stale cigarette smoke.Now scientists say they have measured levels of such “thirdhand” smoke, suggesting it is carried on the bodies and clothing of moviegoers and could be a prominent, and lingering, source of hazardous chemicals.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 4, 2020 Category: Science Authors: Nicola Davis Tags: Health Smoking Society Film Culture World news Science Source Type: news

Doctors try CRISPR gene editing in a person's body for the 1st time
Scientists say they have used the gene editing tool CRISPR inside someone's body for the first time, a new frontier for efforts to operate on DNA, the chemical code of life, to treat diseases. (Source: CBC | Health)
Source: CBC | Health - March 4, 2020 Category: Consumer Health News Tags: News/Health Source Type: news

Coronavirus: Debunking Myths And Misinformation
(CNN) — As the novel coronavirus — and panic about the coronavirus — continues to spread around the world, so too are bogus claims, conspiracy theories and misinformation about the disease. There’s so much inaccurate information floating around out there that the World Health Organization is calling it an “infodemic.” In perhaps the clearest sign of the times, WHO has joined TikTok to help set the record straight. Read: Coronavirus – What You Should And Shouldn’t Do The myths exist both on the fringes of the internet and in more mainstream outlets. And while social media...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 4, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Coronavirus Source Type: news

Household chemical use linked to child language delays
(Ohio State University) Young children from low-income homes whose mothers reported frequent use of toxic chemicals such as household cleaners were more likely to show delays in language development by age 2, a new study found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2020 Category: International Medicine & Public Health Source Type: news

SMART announces revolutionary new process for scientific applications
(Singapore-MIT Alliance for Research and Technology (SMART)) Researchers at Singapore-MIT Alliance for Research and Technology (SMART) and National University Singapore (NUS) have developed a unique method for generating and processing fluid droplets under previously unattainable conditions, providing an affordable and accessible way for chemical and biological reactions to take place in a completely isolated environment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 4, 2020 Category: Cancer & Oncology Source Type: news

Expanding the plasmonic painter's palette
(American Chemical Society) By blending paints in their palette, artists can create a broad spectrum of colors with subtly different hues. However, scientists who wish to create a similar range of structural colors, like those found on butterfly wings, are much more limited. Now, researchers reporting in ACS Nano have developed a new method for mixing plasmonic red, blue and green to yield a virtually unlimited number of colors that could be used for new types of displays.   (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 4, 2020 Category: International Medicine & Public Health Source Type: news

Third-hand smoke is no joke, can convey hazardous chemicals
(Yale University) People can carry hazardous compounds from cigarette smoke that cling to their bodies and clothes and then release those compounds into non-smoking environments -- exposing people nearby to cigarettes' adverse effects, a new study shows. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2020 Category: International Medicine & Public Health Source Type: news

Chemical Industry Executive Nominated to Lead Consumer Watchdog Agency
Nancy B. Beck, who once directed science policy at the American Chemistry Council, was nominated to lead the Consumer Product Safety Commission, which guards against dangerous products (Source: NYT Health)
Source: NYT Health - March 4, 2020 Category: Consumer Health News Authors: Lisa Friedman Tags: Global Warming Environment Greenhouse Gas Emissions Hazardous and Toxic Substances Consumer Protection Chemicals Regulation and Deregulation of Industry American Chemistry Council Consumer Product Safety Commission Beck, Nancy B Trump, Source Type: news

‘Chasing a ghost’: dark chemical matter and the cause of colon cancer
Seven years ago, Jason Crawford, Ph.D., began chasing a ghost: a bacterial toxin named colibactin. Four years later he asked Seth Herzon, Ph.D., to join him. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 3, 2020 Category: Universities & Medical Training Source Type: news

Webinar on current access to TOXNET resources
NLM staff will participate in the next American Chemical Society webinar for the chemical information and cheminformatics community: An Overview of NLM’s Post-TOXNET Resources. TOXNET (the TOXicology Data NETwork) was retired in December 2019 as part of the reorganization associated … Continue reading → (Source: NCBI Insights)
Source: NCBI Insights - March 3, 2020 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New chemical safety pubchem Source Type: news

Men can SMELL when a woman is aroused and find them to be 'more attractive' when sexually excited
The investigation into carnal lust by the University of Kent found exposure to the chemical signals emanating from female sweat increases the sexual arousal levels of men. (Source: the Mail online | Health)
Source: the Mail online | Health - March 3, 2020 Category: Consumer Health News Source Type: news

Responding to Coronavirus Testing Problems, US Government Expands Number of Labs That Can Run Tests
After a slow and criticized rollout of U.S. government-designed testing kits for the novel coronavirus COVID-19, federal agencies enforced new policies to scale up capacity to conduct tests and produce results more quickly. On Feb. 29, the US Food and Drug Administration (FDA) expanded its Emergency Use Authorization (EUA) policy to allow more labs to apply for approval to conduct testing for COVID-19. Until the announcement, two labs run by the Centers for Disease Control and Prevention (CDC) and a few state labs were the only ones in the country that could test for the disease. Expanding the number of labs that can perfo...
Source: TIME: Health - March 3, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Infectious Disease Source Type: news

Responding to Coronavirus Testing Problems, U.S. Government Expands Number of Labs That Can Run Tests
After a slow and criticized rollout of U.S. government-designed testing kits for the novel coronavirus COVID-19, federal agencies enforced new policies to scale up capacity to conduct tests and produce results more quickly. On Feb. 29, the US Food and Drug Administration (FDA) expanded its Emergency Use Authorization (EUA) policy to allow more labs to apply for approval to conduct testing for COVID-19. Until the announcement, two labs run by the Centers for Disease Control and Prevention (CDC) and a few state labs were the only ones in the country that could test for the disease. Expanding the number of labs that can perfo...
Source: TIME: Health - March 3, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Infectious Disease Source Type: news

Developing anti-icing airfield runways using surface embedded heat wires and renewable energy - Heymsfield E, Daniels JW, Saunders RF, Kuss ML.
Airfield runway safety is significantly affected by winter snow, ice, and slush conditions. These wet wintry conditions impact aircraft control and stopping distances. Airport operators use deicing chemicals and plowing to maintain safe runways during wet ... (Source: SafetyLit)
Source: SafetyLit - March 3, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Study: PFAS act similar to known cancer-causing chemicals
(Environmental Working Group) Scientists at the Environmental Working Group and Indiana University have for the first time conducted a review of 26 fluorinated chemicals, or PFAS, and found that all display at least one characteristic of known human carcinogens. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 3, 2020 Category: Cancer & Oncology Source Type: news

Chemists inhibit a critical gear of cell immortality
(Northwestern University) Researchers have developed a promising molecular tool that targets and inhibits one of cell immortality's underlying gears: the enzyme telomerase. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 3, 2020 Category: Cancer & Oncology Source Type: news

New DNA origami motor breaks speed record for nano machines
(Emory Health Sciences) Through a technique known as DNA origami, scientists have created the fastest, most persistent DNA nano motor yet. Angewandte Chemie published the findings, which provide a blueprint for how to optimize the design of motors at the nanoscale -- hundreds of times smaller than the typical human cell. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 3, 2020 Category: Biology Source Type: news

Company claims its product kills coronavirus without FDA approval
Enviro-Master said that its medical grade cleaning product can kill coronavirus, but the American Chemistry Council didn't include the product on its list of pre-approved disinfectants. (Source: the Mail online | Health)
Source: the Mail online | Health - March 3, 2020 Category: Consumer Health News Source Type: news

President Proposes 27 Percent Cut to EPA
The budget for the Environmental Protection Agency would be slashed by $2.4 billion or 27 percent in FY 2021 if the President has his way. Overall the regulatory agency would receive $6.6 billion. The Administration proposed drastic cuts to EPA’s budget in FY 2018, FY 2019, and FY 2020 as well. These were rejected by Congress. The budget prioritizes support for core programs and infrastructure for a “cleaner healthier environment,” collaborations with state, tribal and federal partners, and creating “consistency and certainty for the regulated community” by removing redundant regulations, mod...
Source: Public Policy Reports - March 2, 2020 Category: Biology Authors: AIBS Source Type: news

NTP board discusses reinventing tox testing, new research topics
Focus is on using approaches more relevant to humans when studying chemicals. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - March 2, 2020 Category: Environmental Health Source Type: news

Texas Criminal Trial Highlights Climate Liability For Factories In Floodplains
A criminal case in Houston alleges that employees at a chemical company should have prepared for the record flooding caused by Hurricane Harvey.(Image credit: Brendan Smialowski/AFP/Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - March 2, 2020 Category: Consumer Health News Authors: Rebecca Hersher Source Type: news

Health regulators seized 3.5million unlicensed erection pills last year
EXCLUSIVE: The Government's MHRA seized fake pills at UK borders amounting to more than £10million in 2019. Copycat versions could be cut with toxic chemicals. (Source: the Mail online | Health)
Source: the Mail online | Health - March 2, 2020 Category: Consumer Health News Source Type: news

Earth may have been a 'water world' 3bn years ago, scientists find
Chemical signatures in ancient ocean crust point to a planet without continentsScientists have found evidence that Earth was covered by a global ocean that turned the planet into a “water world” more than 3bn years ago.Telltale chemical signatures were spotted in an ancient chunk of ocean crust which point to a planet once devoid of continents, the largest landmasses on Earth.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - March 2, 2020 Category: Science Authors: Ian Sample Science editor Tags: Science Oceans Geology Palaeontology World news Source Type: news

Carbon chains can adopt fusilli or spaghetti type shapes depending if they have odd or even numbers of atoms
Helical shapes are very familiar in the natural world and, at the molecular level, of DNA, the very blueprint of life itself. (Source: University of Bristol news)
Source: University of Bristol news - March 2, 2020 Category: Universities & Medical Training Tags: Research; Faculty of Science, Faculty of Science, School of Chemistry; Press Release Source Type: news

Generations of Insect Attacks Drive Plants to "Talk" Publicly
Goldenrods that evolved in the presence of herbivores release volatile chemicals that trigger defenses in neighboring plants of their species, even those that are genetically unrelated. (Source: The Scientist)
Source: The Scientist - March 1, 2020 Category: Science Tags: Notebook Magazine Issue Source Type: news

MCMi (Medical Countermeasures Initiative) Program Update: FY 2019
Source: U.S. Food and Drug Administration (FDA). Published: 3/2020. This 53-page annual report details the Food and Drug Administration (FDA)'s medical countermeasures (MCM) activities in fiscal year (FY) 2019 (October 1, 2018 – September 30, 2019). FDA’s overarching objective with respect to MCMs is to facilitate the timely development of and access to safe and effective MCMs to counter chemical, biological, radiological, and nuclear (CBRN) and emerging infectious disease threats for civilian populations, as well as MCMs to support American military personnel. (PDF) (Source: Disaster Lit: Resource Guide for D...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 1, 2020 Category: International Medicine & Public Health Source Type: news

Pharmacokinetic evaluation of brain penetrating morpholine-3-hydroxy-2-pyridine oxime as an antidote for nerve agent poisoning - Zorbaz T, Mi šetić P, Probst N, Žunec S, Zandona A, Mendaš G, Micek V, Maček Hrvat N, Katalinić M, Braïki A, Jean L, Renard PY, Gabelica Marković V, Kovarik Z.
Nerve agents, the deadliest chemical warfare agents, are potent inhibitors of acetylcholinesterase (AChE) and cause rapid cholinergic crisis with serious symptoms of poisoning. Oxime reactivators of AChE are used in medical practice in treatment of nerve a... (Source: SafetyLit)
Source: SafetyLit - February 29, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Population-level investigation of the knowledge of ocular chemical injuries and proper immediate action - Seraj H, Khawandanh S, Fatani A, Saeed A, Alotaibi G, Basheikh A.
OBJECTIVE: Although the eyes occupy 0.1% of the total body surface, eye injuries are serious because vision is arguably the most important sense. We aimed to assess knowledge of Saudi Arabian residents regarding steps to be taken in cases of chemical eye i... (Source: SafetyLit)
Source: SafetyLit - February 29, 2020 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Detection of chemical weapon nerve agents in bone by liquid chromatography-mass spectrometry - Rubin KM, Goldberger BA, Garrett TJ.
A recently proposed model for the incorporation of xenobiotics of forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relatively elevated concentrations based on their unique chemical properties. To test ... (Source: SafetyLit)
Source: SafetyLit - February 29, 2020 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

The influence of social capital on protective action perceptions towards hazardous chemicals - Liu T, Zhang H, Zhang H.
The stigmatized character of hazardous chemicals has caused individuals in hazards to take excessive protective actions. Here, social capital is introduced to discuss its influence on the protective action decision model (PADM), considering this variable h... (Source: SafetyLit)
Source: SafetyLit - February 29, 2020 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

CDC Broadens'Person Under Investigation' Definition for COVID-19 CDC Broadens'Person Under Investigation' Definition for COVID-19
New tests are being manufactured without a problematic chemical, and the PUI definition was revised'to meet the needs of this rapidly evolving situation. 'Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - February 29, 2020 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Researchers announce progress in developing an accurate, noninvasive urine test for prostate cancer
(Johns Hopkins Medicine) Researchers at the Johns Hopkins Kimmel Cancer Center have made significant progress toward development of a simple, noninvasive liquid biopsy test that detects prostate cancer from RNA and other specific metabolic chemicals in the urine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 28, 2020 Category: International Medicine & Public Health Source Type: news

New state-of-the-MOF materials
(Kyoto University) Metal-organic frameworks (MOFs) are porous, crystalline materials that can trap compounds within their molecular cavities, giving them a wide range of applications in gas storage and separation, carbon capture, and in the catalysis of chemical reactions, to name a few. A new range of applications are now being investigated by converting crystalline MOFs into liquid and/or glassy states. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 28, 2020 Category: Biology Source Type: news

Established Conditions: Reportable CMC Changes for Approved Drug and Biologic Products Guidance for Industry
This guidance has been developed to address the lack of clarity with respect to what chemistry, 17 manufacturing, and controls (CMC) information in a marketing application constitutes an 18 established condition or a “regulatory commitment” that, if changed following approval, requires 19 reporting (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 27, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Bayer faces more claims over weedkiller cancer allegations
Rise in plaintiffs comes as German chemicals group reports 19% jump in sales (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - February 27, 2020 Category: Pharmaceuticals Source Type: news

Study sheds light on how a drug being tested in COVID-19 patients works
(American Society for Biochemistry and Molecular Biology) As hospitalized COVID-19 patients undergo experimental therapy, research published in the Journal of Biological Chemistry explains how the drug, remdesivir, stops replication in coronaviruses. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 27, 2020 Category: International Medicine & Public Health Source Type: news

Cells carrying Parkinson's mutation could lead to new model for studying disease
(University of Wisconsin-Madison) Parkinson's disease researchers have used gene-editing tools to introduce the disorder's most common genetic mutation into marmoset monkey stem cells and to successfully tamp down cellular chemistry that often goes awry in Parkinson's patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 27, 2020 Category: International Medicine & Public Health Source Type: news

Polymers get caught up in love-hate chemistry of oil and water
(DOE/Oak Ridge National Laboratory) Researchers at Oak Ridge National Laboratory and the University of Tennessee achieved a rare look at the inner workings of polymer self-assembly at an oil-water interface to advance materials for neuromorphic computing and bio-inspired technologies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 27, 2020 Category: Biology Source Type: news

Brewing greener chemicals from fermented waste
Your dinner leftovers, vegetable peelings and discarded packaging paper could provide environmentally friendly alternatives to commonly used chemicals, thanks to innovative technologies and fermentation processes being developed by EU and industry-funded researchers. (Source: EUROPA - Research Information Centre)
Source: EUROPA - Research Information Centre - February 27, 2020 Category: Research Source Type: news