A View of Aging Centered Around the Capacity for Hormesis
It is not too far from the truth to say that everyone in the field of aging research has their own theory of aging. Enormous amounts of data exists, measurements of near every aspect of cellular biochemistry, to note the ways in which these aspects change with age, yet we lack the framework to link all of the data together, to firmly state what is important and what is not, what is cause, what is consequence, and how exactly the network of age-related changes are linked to one another. Aging is a dark forest in which the boundaries are well mapped, but only a few of the interior features have been well explored.
So ...
Source: Fight Aging! - September 28, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Money Is a Psychedelic Too
Money is actually psychedelic. Let me ‘splain…
Money isn’t as intense as the psychedelics you put directly into your body – physical consumption changes the intentionality – but money still behaves very much as a psychedelic substance.
Money responds powerfully to set and setting, the set being your mindset and the setting behind the environment of other relationships that you bring to your interactions with money.
When this realization popped in, I asked my higher self if this was true, and he said, “Bingo! Indeed it is.”
I see this very clearly in my own relationship with money as it...
Source: Steve Pavlina's Personal Development Blog - September 27, 2023 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Abundance Creating Reality Source Type: blogs
Diversity Supplement Program Paves the Way for Talented Researchers
“I hope that one day I’m able to increase our understanding of evolution, and I also hope to increase access to research. I want others to know that this space is open to people who look like me, who come from disadvantaged backgrounds, and who are underrepresented in the sciences,” says Nkrumah Grant, Ph.D., a postdoctoral research associate (postdoc) in microbiology and molecular genetics at Michigan State University (MSU) in East Lansing.
Dr. Grant’s work receives support from the NIGMS Diversity Supplement Program (DSP), which is designed to improve the recruitment and training of promising researchers from ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 27, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Diseases Microbes Profiles Training Source Type: blogs
Biomimetic Scaffolds to Encourage Bone and Cartilage Regrowth
One of the areas of research that seems constantly on the verge of producing an impressive advance is the use of nanoscale scaffold materials to encourage regrowth of tissue, such as bone and cartilage. The space of possible combinations of techniques is vast, and there only so many researchers, and only so much funding. Advances such as the one noted here are published by research groups several times a year, and this has been the case for more than a decade now. This part of the field seems eternally in a state of progress and exploration, with promising leads, yet it remains the case that clinical options for regenerati...
Source: Fight Aging! - September 27, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Dichloroacetate
Treating my terminal disease like a research problem and finding a lead. (Source: Depth-First)
Source: Depth-First - September 26, 2023 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs
“PictureWhat” ??? Super-Human Poison Ivy. What’s Going On?
By MIKE MAGEE
Connecticut loves its’ trees. And no town in Connecticut loves its’ trees more than West Hartford, CT. The town borders include an elaborate interconnected reservoir system that does double duty as a focal point for a wide range of nature paths for walkers, runners and cyclists.
While walking one path yesterday, I came a tree with the healthiest upward advancing vine I had ever seen. My “PictureThis” app took no time to identify the plant. To my surprise, it was Toxicodendron radicans, known commonly as Poison Ivy.
The description didn’t pull punches. It read, “In pop culture, poison ivy ...
Source: The Health Care Blog - September 20, 2023 Category: Consumer Health News Authors: matthew holt Tags: Non-Health Global Warming Mike Magee Poison Ivy Source Type: blogs
In Other Words: Sandboxes Aren ’t Just for Kids
Did you know that kids aren’t the only ones playing around in sandboxes? The term sandbox may evoke a childhood memory of sensory play, but it’s also used to describe a virtual environment where someone can learn from digital products.
Credit: NIGMS.
High quantities of data that can be hard to manage, store, and understand are increasingly driving biomedical research. Scientists need access to high-performance computer infrastructure along with bioinformatics tools to do cutting-edge research, but often these resources are out of reach for smaller institutions. Cloud computing can provide access to top-of-the...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 20, 2023 Category: Research Authors: Chrissa Chverchko Tags: Tools and Techniques Bioinformatics Computational Biology Cool Tools/Techniques In Other Words Source Type: blogs
DNA is Better at Math than You Are
By KIM BELLARD
I was tempted to write about the work being done at Wharton that suggests that AI may already be better at being entrepreneurial than most of us, and of course I’m always interested to see how nanoparticles are starting to change health care (e.g., breast cancer or cancer more generally), but when I saw what researchers at China’s Shanghai Jiao Tong University have done with DNA-based computers, well, I couldn’t pass that up.
If PCs helped change the image of computers from the big mainframes, and mobile phones further redefined what a computer is, then DNA computers may cause us to one day...
Source: The Health Care Blog - September 20, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Tech DNA Future of Computing Kim Bellard Source Type: blogs
Chatting Apton Acquisition with PacBio CEO Christian Henry
PacBio CEO Christian Henry chatted with me recently by teleconference on a variety of topics, but the focus was the recent PacBio acquisition of Apton Biosystems for $85M in equity. As a regular reminder, my employer’s CEO reports in a sense to Henry, as he’s on the Board of Directors. A particularly interesting revelation by Henry is that PacBio had its eye on Apton in late 2021, essentially as soon as they completed theOmniome acquisition announced in July 2021 that formed the foundation for their now-released Onso short read instrument. PacBio believed then that the desktop instrument design from Omniome...
Source: Omics! Omics! - September 19, 2023 Category: Bioinformatics Authors: Keith Robison Source Type: blogs
Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Mitochondrial Epigenetics in Age-Related Mitochondrial Dysfunction
The hundreds of mitochondria present in every cell in the body undertake the essential duty of producing chemical energy store molecules, adenosine triphosphate (ATP), used to power the cell. With age, mitochondria become less efficient and more damaged, generating oxidative stress and triggering inflammation while producing less ATP than is optimal. This is thought to be a major contribution to degenerative aging, though as for all contributions to aging, it requires a highly targeted way to improve mitochondrial function in order to determine just how important it is. That highly targeted therapy doesn't yet exist in a u...
Source: Fight Aging! - September 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Times They Are A-Changing … .Fast
By KIM BELLARD
If you have been following my Twitter – oops, I mean “X” – feed lately, you may have noticed that I’ve been emphasizing The Coming Wave, the new book from Mustafa Suleyman (with Michael Bhaskar). If you have not yet read it, or at least ordered it, I urge you to do so, because, frankly, our lives are not going to be the same, at all. And we’re woefully unprepared.
One thing I especially appreciated is that, although he made his reputation in artificial intelligence, Mr. Suleyman doesn’t only focus on AI. He also discusses synthetic biology, quantum computing, robotics, and new energ...
Source: The Health Care Blog - September 14, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Kim Bellard quantum computing Smart Pills synthetic biology The Coming Wave Source Type: blogs
Reviewing Evidence for Urolithin A Supplementation
Mitochondria are the power plants of the cell, responsible for generating chemical energy store molecules to power cell processes. Urolithin A is one of a number of supplements shown to improve mitochondrial function, though as for the others it isn't all that impressive when compared to the effects of regular exercise. Nonetheless, this and other approaches to modestly attenuate age-related declines in mitochondrial function are under active development. They are not solutions to the problem of mitochondrial aging, however. For that we must look to more radical approaches to therapy, such as mitochondrial transplantation,...
Source: Fight Aging! - September 14, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Progression
The Standard of Care treatment fails. (Source: Depth-First)
Source: Depth-First - September 14, 2023 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs
Are Pharmacists Really Just Shopkeepers With A Strong Line In Pills?
This appeared
last week:
Chemists protest medicine rule change in angry walk out
Tom McIlroy Political correspondent
Sep 4, 2023 –
5.37pm
Pharmacists
have staged an angry walk-out of federal parliament, protesting the Albanese
government’s moves to allow more than 4 million consumers to buy two months’ worth of
medicine for the price of a single prescription.
Hundreds
of pharmacists were in (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - September 14, 2023 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
