Smoking Cessation Drug Tied to Increased Cardiovascular Risk
Varenicline associated with increased incidence of CV events in first 12 weeks after receipt of drug (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 11, 2014 Category: Psychiatry Tags: Cardiology, Family Medicine, Gynecology, Internal Medicine, Neurology, Nursing, Pharmacy, Psychiatry, Pulmonology, Journal, Source Type: news

Pharmaceutical Aids Not Found to Be Helpful for Smoking Cessation
No evidence that varenicline, bupropion, or nicotine replacement increase probability of abstinence (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Cardiology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Nursing, Oncology, Pharmacy, Pulmonology, Journal, Source Type: news

Varenicline poisoning for a suicidal purpose - Sørup FH, Neumann AB, Holst H.
We report a history of a 45-year-old woman who ingested 40-50 mg varenicline. She... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 31, 2014 Category: Global & Universal Tags: Poisoning Source Type: news

FDA Advisers Vote to Keep Black-Box Warning on Chantix (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD An FDA advisory panel voted late last week to keep the black-box warning on the smoking cessation drug varenicline … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 20, 2014 Category: Primary Care Source Type: news

FDA panel supports retaining Chantix boxed warning for now
Read the full story on MD Consult: FDA panel supports retaining Chantix boxed warning for now (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - October 20, 2014 Category: Journals (General) Source Type: news

FDA Advisers Vote to Keep Black-Box Warning on Chantix (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD An FDA advisory panel voted late last week to keep the black-box warning on the smoking cessation drug varenicline … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 20, 2014 Category: Primary Care Source Type: news

D.C. Week: Of Travel Bans and Chantix
(MedPage Today) -- Recess notwithstanding, Congress had advice on Ebola. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - October 18, 2014 Category: Respiratory Medicine Source Type: news

Black Box Warning Should Remain on Chantix: FDA Panel
(Source: WebMD Health)
Source: WebMD Health - October 17, 2014 Category: Consumer Health News Source Type: news

Keep Chantix Black Box Warning, FDA Panel SaysKeep Chantix Black Box Warning, FDA Panel Says
An FDA panel recommends waiting for data from an ongoing study designed to capture serious neuropsychiatric adverse events related to Chantix before making a final decision on the black box warning. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 17, 2014 Category: Consumer Health News Tags: Psychiatry News Source Type: news

FDA Panel: Chantix Boxed Warning Should Stay (CME/CE)
(MedPage Today) -- Some panelists said it doesn't go far enough. (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - October 16, 2014 Category: Geriatrics Source Type: news

FDA panel votes to keep severe warning on Pfizer anti-smoking drug
(Reuters) - Pfizer Inc failed to convince the U.S. Food and Drug Administration to remove a black box warning on its controversial quit-smoking drug Chantix, with an advisory panel to the agency voting against the removal on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - October 16, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Pfizer, FDA Square Off on Chantix Psych Risk
(MedPage Today) -- Agency staff say black-box warning on smoking-cessation aid should stay. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - October 15, 2014 Category: Respiratory Medicine Source Type: news

FDA Staff: Chantix Should Keep Neuropsychiatric Warning on Label (FREE)
By Kelly Young Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM FDA officials are recommending that the smoking … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 15, 2014 Category: Primary Care Source Type: news

FDA staff recommend Pfizer keep black box warning on anti-smoking drug
(Reuters) - Pfizer Inc's quit-smoking drug Chantix received its latest setback on Tuesday after U.S. Food and Drug Administration staff recommended that the drugmaker keep a severe warning on the treatment's label. (Source: Reuters: Health)
Source: Reuters: Health - October 14, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

Morning Break: Ebola Scares, Chantix Faceoff
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff. (Source: MedPage Today Pulmonary)
Source: MedPage Today Pulmonary - October 14, 2014 Category: Respiratory Medicine Source Type: news

Smoking rates fall 1% in past year
18.7% of adults in UK now smoke, says ONSRelated items from OnMedicaSmoking cessationCombining varenicline with nicotine patch boosts quit rates11 million working days lost to smokingHelp smokers cut down if they can’t quitE-cigarettes may not help smokers quit (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 7, 2014 Category: UK Health Source Type: news

11 million working days lost to smoking
235,000 smokers sign up to Stoptober campaign to quitRelated items from OnMedicaE-cigarettes may not help smokers quitSmoking cessationCombining varenicline with nicotine patch boosts quit ratesPublic must own responsibility for their healthRoll-ups worse than factory-made cigarettes (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 3, 2014 Category: UK Health Source Type: news

Varenicline Label Changes Downplay Suicide RiskVarenicline Label Changes Downplay Suicide Risk
New data suggest lower neuropsychiatric risks with the smoking cessation drug varenicline. The FDA is set to review these new safety data at an upcoming meeting. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 30, 2014 Category: Consumer Health News Tags: Psychiatry News Source Type: news

New FDA Label Touts Chantix Safety; Pfizer Pushes to Remove Black Box
The FDA updated the label of Pfizer's anti-smoking drug Chantix to include data from a number of recent studies that found little to no evidence of psychiatric problems or suicidal tendencies in patients taking the drug. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - September 25, 2014 Category: Pharmaceuticals Source Type: news

Chantix Label Revision Casts Doubt on Link to Suicidality (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, FASAM The addition of new data to the varenicline (Chantix) label suggests that the smoking-cessation drug may be safer … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 25, 2014 Category: Primary Care Source Type: news

Varenicline and Cardiovascular Adverse EventsVarenicline and Cardiovascular Adverse Events
How strong is the evidence suggesting that varenicline is cardiotoxic? Read this review to find out. Therapeutic Advances in Drug Safety (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 22, 2014 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include a look at neuropathic pain treatment, infusion pumps for hard to control diabetes, screening for carotid artery stenosis, and varenicline and nicotine replacement for smoking cessation. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 11, 2014 Category: Cardiology Source Type: news

Study: combination of varenicline and nicotine patch best way to quit smoking
Brooks HaysWASHINGTON, July 9 (UPI) -- The best way to quit smoking, researchers say, is a combination of a drug called varenicline and the use of nicotine patches. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 9, 2014 Category: Consumer Health News Source Type: news

Combining varenicline with nicotine patch boosts quit rates
Quitters more likely not to be smoking at six months with combination than with varenicline aloneRelated items from OnMedicaFewer smokers are using NHS help to quitSmoking cessationEU moves to make smoking less attractive to young smokersRoll-ups worse than factory-made cigarettesE-cigarettes may not help smokers quit (Source: OnMedica Latest News)
Source: OnMedica Latest News - July 9, 2014 Category: UK Health Source Type: news

Combo Approach May Work Best for Smokers Looking to Quit
Study finds drug Chantix plus nicotine patch beats use of the patch alone (Source: WebMD Health)
Source: WebMD Health - July 8, 2014 Category: Consumer Health News Source Type: news

Patch Plus Pill Better to Help Smokers Quit (CME/CE)
(MedPage Today) -- Adding a nicotine patch to varenicline (Chantix) during quit-smoking attempts substantially improved short-term success in kicking the addiction, a trial showed. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 8, 2014 Category: Primary Care Source Type: news

Combo Approach May Work Best for Smokers Looking to Quit
Study finds drug Chantix plus nicotine patch beats use of the patch alone Source: HealthDay Related MedlinePlus Page: Quitting Smoking (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 8, 2014 Category: Consumer Health News Source Type: news

More Evidence Drug Combo Helps Smokers QuitMore Evidence Drug Combo Helps Smokers Quit
The combination of varenicline and bupropion proves successful in an 'adaptive' smoking cessation paradigm. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 3, 2014 Category: Consumer Health News Tags: Psychiatry News Source Type: news

E-cigs 'better than patches and gum' as quitting aid
Conclusion This was a useful “real world” survey, which involved a large nationally representative sample of adults in England. Researchers adjusted their results for a large number of potential confounders, including the degree of nicotine dependence and the time elapsed since participants’ attempt to quit begun. However, as the authors point out, this was not an RCT, which is the best method of determining the effectiveness of treatments. This means that measured and unmeasured confounders could have affected the results.  Another important limitation is the study’s reliance on adults self-...
Source: NHS News Feed - May 21, 2014 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news

No age discrimination pledge in drugs appraisals
NICE launches consultation on how it assesses drugs and treatments Related items from OnMedicaStart varenicline sooner to boost successSleeping pills linked to fourfold death riskNew guidance for elderly with high BP‘Scorecards’ will eradicate NHS drug inequalitySugar not saturated fat is the major issue for CVD (Source: OnMedica Latest News)
Source: OnMedica Latest News - March 28, 2014 Category: UK Health Source Type: news

More Evidence Varenicline Helps Mentally Ill Quit SmokingMore Evidence Varenicline Helps Mentally Ill Quit Smoking
Varenicline helps smokers with serious mental illness abstain from smoking, new research shows. But at least 1 expert is still not entirely convinced of its safety in this patient population. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - February 10, 2014 Category: Psychiatry Tags: Psychiatry News Source Type: news

Medication may help patients with severe mental illness stay smoke-free
Smokers with schizophrenia or bipolar disorders are three times more likely to abstain from smoking over the course of a year if they take varenicline. Although varenicline is an FDA-approved smoking cessation medication, it had not been proven effective for smokers with severe mental illness. The... (Source: NIDA News)
Source: NIDA News - February 4, 2014 Category: Addiction Tags: Mental Health, Prevention Research Source Type: news

Drug Combo Boosts Early Quit Rates in SmokersDrug Combo Boosts Early Quit Rates in Smokers
Combining varenicline with bupropion may boost early quit rates compared with varenicline alone; heavier smokers most likely to benefit. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - January 9, 2014 Category: Psychiatry Tags: Psychiatry News Source Type: news

Combined Therapy Benefits Cigarette Smokers Trying to Quit Compared to Monotherapy
ROCHESTER, Minn. — Jan. 7, 2014 — Among cigarette smokers, combining the smoking cessation medications varenicline and bupropion, compared with varenicline alone, resulted in higher smoking abstinence rates for one outcome but not the other at three and six months; rates were similar at one year, according to a Mayo Clinic study published this month [...] (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - January 7, 2014 Category: Research Source Type: news

'No serious heart risks' linked to smoking cessation therapies
The American Heart Association claims that three different types of smoking cessation therapies do not pose serious heart risks, quashing concerns that certain products may increase the risks of heart attack, stroke or heart-related death.Researchers looked at the results of 63 clinical trials involving 30, 508 people who were quitting smoking using either nicotine replacement gums and patches, the nicotine addiction treatment varenicline (Chantix), or taking the antidepressant bupropion (Wellbutrin), which can reduce cravings and other unwanted withdrawal effects. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 13, 2013 Category: Consumer Health News Tags: Smoking / Quit Smoking Source Type: news

Quit-smoking drug to make problem drinking 'social'
A drug commonly used to help people quit smoking may also help problem drinkers overcome their addiction.Professor Selena Bartlett from QUT's Institute of Health and Biomedical Innovation (IHBI) and an ambassador for Women in Technology (WiT) said trials would soon begin to test whether varenicline, commonly known as Champix, can effectively treat problem drinkers."It's well known that many people with serious alcohol dependency also smoke so we've been trying to better understand the mechanisms behind that," Professor Bartlett said. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 28, 2013 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Chantix OK with Treated Depression
A new study says that for those who have their depression under control with treatment, it is safe to take the smoking cessation drug Chantix (varenicline). The study follows a 2007 report from the U.S. Food and Drug Administration (FDA) revealing that there had been complaints of suicidal thoughts and erratic behavior in some who used the drug.  The report said that it was not clear whether the drug was to blame for these symptoms or if they were caused by nicotine withdrawal....Read Full Post (Source: About.com Depression)
Source: About.com Depression - September 23, 2013 Category: Psychiatry Source Type: news

Chantix Doesn't Make Depression Worse (CME/CE)
(MedPage Today) -- In patients with a history of major depression, varenicline (Chantix) was associated with a significantly higher smoking cessation rate than placebo with no increased risk of depression, researchers found. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - September 18, 2013 Category: Psychiatry Source Type: news

For smoking cessation in patients with current or past depression varenicline proves safe and effective
Varenicline is safe and effective to help smokers with current or past major depression quit smoking. Approximately half of smokers seeking treatment have a history of depression. This is a clinically important relationship because depression and smoking are among the leading causes of disability and death in the world and having depression makes quitting smoking more difficult. Varenicline has proven more effective than bupropion for smoking cessation, but because of its mechanism of action, there are concerns about the safety of varenicline in patients with psychiatric disorders... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 18, 2013 Category: Consumer Health News Tags: Smoking / Quit Smoking Source Type: news

Chantix may be safe with treated depression: study
NEW YORK (Reuters Health) - In a trial among people with a history of depression, those taking the quit-smoking aid varenicline - marketed in the U.S. as Chantix - were no more prone to depression or thoughts of suicide than those on a placebo, according to a new study. (Source: Reuters: Health)
Source: Reuters: Health - September 17, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

Varenicline's Neuropsychiatric Safety Concerns AllayedVarenicline's Neuropsychiatric Safety Concerns Allayed
A randomized, placebo-controlled, phase 4 postmarketing study suggests varenicline is effective and safe in patients with stably treated current or past depression. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - September 17, 2013 Category: Psychiatry Tags: Psychiatry News Source Type: news

Chantix May Be Safe with Treated Depression
In a trial among people with a history of depression, those taking the quit-smoking aid varenicline - marketed in the U.S. as Chantix - were no more prone to depression or thoughts of suicide than those on a placebo, according to a new study.Source: Reuters Health Related MedlinePlus Pages: Depression, Medicines, Quitting Smoking (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 17, 2013 Category: Consumer Health News Source Type: news

Featured in NEJM Journal Watch: Varenicline Safe and Effective in Smokers with Depression (FREE)
By the NEJM Journal Watch Editors Compared … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 17, 2013 Category: Primary Care Source Type: news

Can E-Cigarettes Help Smokers Quit?
E-cigarettes create controversy and profits - almost equally. New data argue they can help people quit smoking - but will they also promote it?read more (Source: Psychology Today Addiction Center)
Source: Psychology Today Addiction Center - September 12, 2013 Category: Addiction Authors: Matthew J. Edlund, M.D. Tags: Addiction Health aa meetings brilliant designs bupropion cancer candy tastes Chantix chemicals in tobacco chemicals in tobacco smoke cigarette smokers cigarettes e-cigarettes functions of the nervous system harmful chemicals Source Type: news

Psychiatric Medications and Violence - List of...
Table of drugs found by a major study to be associated with an increased risk of violent behavior, and a further discussion of the risks of Chantix. Page 2. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 18, 2013 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Varenicline plus counseling elevates quit rate
Read the full story on MD Consult: Varenicline plus counseling elevates quit rate (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - July 8, 2013 Category: Journals (General) Source Type: news

Varenicline for alcohol dependence? CV events and suicide concerns linger
New research suggests the smoking cessation drug varenicline may aid in the treatment of alcohol dependence, but reaction to the study suggests this approach may face some hurdles. (Source: theHeart.org)
Source: theHeart.org - June 7, 2013 Category: Cardiology Source Type: news

Drug May Aid in Alcohol Dependence, but Safety Concerns LingerDrug May Aid in Alcohol Dependence, but Safety Concerns Linger
Varenicline may aid in the treatment of alcohol dependence, preliminary research shows. However, concerns about an increased risk for suicidal thoughts and cardiovascular events linger. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 6, 2013 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Chantix May Treat Alcohol Dependence and Abuse
Anti-smoking Medication Shows Promise for Treating Alcohol Dependence (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 5, 2013 Category: Journals (General) Source Type: news

Varenicline May Have Edge in Helping Smokers QuitVarenicline May Have Edge in Helping Smokers Quit
Smokers who get counseling to help them quit do better if they also get medication, researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 1, 2013 Category: Consumer Health News Tags: Psychiatry News Source Type: news