Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review
Oxid Med Cell Longev. 2022 Aug 26;2022:7743705. doi: 10.1155/2022/7743705. eCollection 2022.ABSTRACTMolecules with at least one unpaired electron in their outermost shell are known as free radicals. Free radical molecules are produced either within our bodies or by external sources such as ozone, cigarette smoking, X-rays, industrial chemicals, and air pollution. Disruption of normal cellular homeostasis by redox signaling may result in cardiovascular, neurodegenerative diseases and cancer. Although ROS (reactive oxygen species) are formed in the GI tract, little is known about how they contribute to pathophysiology and di...
Source: Atherosclerosis - September 5, 2022 Category: Cardiology Authors: Sheikh Shohag Shomaya Akhter Shahidul Islam Tonmoy Sarker Moinuddin Khan Sifat Md Mominur Rahman Md Rezaul Islam Rohit Sharma Source Type: research
Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of < em > Centella asiatica < /em > L. leaves, and < em > in vitro < /em > derived leaves-calli through tissue culture: a potential for biofouling-prevention
Biofouling. 2022 Sep 5:1-14. doi: 10.1080/08927014.2022.2117034. Online ahead of print.ABSTRACTExtracts of Centella asiatica leaves (LEs), and in-vitro leaf-calli (CEs), were investigated for antibacterial, antibiofilm, and anti-quorum sensing activities. Ethyl acetate extracts from leaves (EALE), leaf-calli (EACE), methanolic extracts from leaves (MELE), and leaf-calli (MECE) showed antibacterial activity; the minimum inhibitory concentrations (MICs) of LEs and CEs ranged from 0.312-2.50 mg ml-1 and 0.625 - 2.50 mg ml-1, respectively. The MICs of EALE and EACE were 2.50 mg ml-1, each, for C. violaceum 12742, and P. aerugi...
Source: Biofouling - September 5, 2022 Category: Molecular Biology Authors: Mo Ahamad Khan Haris M Khan Irfan Bashir Ganie Sachin Kumar Anwar Shahzad Ismail Celik Mohammad Shahid Source Type: research
Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of < em > Centella asiatica < /em > L. leaves, and < em > in vitro < /em > derived leaves-calli through tissue culture: a potential for biofouling-prevention
Biofouling. 2022 Sep 5:1-14. doi: 10.1080/08927014.2022.2117034. Online ahead of print.ABSTRACTExtracts of Centella asiatica leaves (LEs), and in-vitro leaf-calli (CEs), were investigated for antibacterial, antibiofilm, and anti-quorum sensing activities. Ethyl acetate extracts from leaves (EALE), leaf-calli (EACE), methanolic extracts from leaves (MELE), and leaf-calli (MECE) showed antibacterial activity; the minimum inhibitory concentrations (MICs) of LEs and CEs ranged from 0.312-2.50 mg ml-1 and 0.625 - 2.50 mg ml-1, respectively. The MICs of EALE and EACE were 2.50 mg ml-1, each, for C. violaceum 12742, and P. aerugi...
Source: Biofouling - September 5, 2022 Category: Molecular Biology Authors: Mo Ahamad Khan Haris M Khan Irfan Bashir Ganie Sachin Kumar Anwar Shahzad Ismail Celik Mohammad Shahid Source Type: research
Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of < em > Centella asiatica < /em > L. leaves, and < em > in vitro < /em > derived leaves-calli through tissue culture: a potential for biofouling-prevention
Biofouling. 2022 Sep 5:1-14. doi: 10.1080/08927014.2022.2117034. Online ahead of print.ABSTRACTExtracts of Centella asiatica leaves (LEs), and in-vitro leaf-calli (CEs), were investigated for antibacterial, antibiofilm, and anti-quorum sensing activities. Ethyl acetate extracts from leaves (EALE), leaf-calli (EACE), methanolic extracts from leaves (MELE), and leaf-calli (MECE) showed antibacterial activity; the minimum inhibitory concentrations (MICs) of LEs and CEs ranged from 0.312-2.50 mg ml-1 and 0.625 - 2.50 mg ml-1, respectively. The MICs of EALE and EACE were 2.50 mg ml-1, each, for C. violaceum 12742, and P. aerugi...
Source: Biofouling - September 5, 2022 Category: Molecular Biology Authors: Mo Ahamad Khan Haris M Khan Irfan Bashir Ganie Sachin Kumar Anwar Shahzad Ismail Celik Mohammad Shahid Source Type: research
Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of < em > Centella asiatica < /em > L. leaves, and < em > in vitro < /em > derived leaves-calli through tissue culture: a potential for biofouling-prevention
Biofouling. 2022 Sep 5:1-14. doi: 10.1080/08927014.2022.2117034. Online ahead of print.ABSTRACTExtracts of Centella asiatica leaves (LEs), and in-vitro leaf-calli (CEs), were investigated for antibacterial, antibiofilm, and anti-quorum sensing activities. Ethyl acetate extracts from leaves (EALE), leaf-calli (EACE), methanolic extracts from leaves (MELE), and leaf-calli (MECE) showed antibacterial activity; the minimum inhibitory concentrations (MICs) of LEs and CEs ranged from 0.312-2.50 mg ml-1 and 0.625 - 2.50 mg ml-1, respectively. The MICs of EALE and EACE were 2.50 mg ml-1, each, for C. violaceum 12742, and P. aerugi...
Source: Biofouling - September 5, 2022 Category: Molecular Biology Authors: Mo Ahamad Khan Haris M Khan Irfan Bashir Ganie Sachin Kumar Anwar Shahzad Ismail Celik Mohammad Shahid Source Type: research
34433 Evaluation of skin mildness of a nature-based acne cleanser in controlled washing test
Background: Acne care depends on gentle yet effective cleansing; however, patients using acne care products often complain of excessive skin dryness and irritation. We developed a nature-based salicylic acid-containing cleanser with mild surfactants including lauryl glucoside, decyl glucoside and skin-soothing centella asiatica extract for acne treatment. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 1, 2022 Category: Dermatology Authors: Sarah McCauley, Hemali B. Gunt Source Type: research
Asiatic acid alleviates liver fibrosis via multiple signaling pathways based on integrated network pharmacology and lipidomics
Eur J Pharmacol. 2022 Aug 10:175193. doi: 10.1016/j.ejphar.2022.175193. Online ahead of print.ABSTRACTLiver fibrosis is characterized by the abnormal deposition of the extracellular matrix with a severe inflammatory response and/or metabolic disorder. Asiatic acid (AA), a natural compound derived from Centella asiatica, exhibited potent anti-fibrosis effects. This investigation first confirmed the anti-fibrosis effects of AA in TGF-β-LX-2 cells and CCl4-induced liver fibrosis mice, and then sought to elucidate a novel mechanism of action by integrating network pharmacology and lipidomics. Network pharmacology was used to ...
Source: European Journal of Pharmacology - August 13, 2022 Category: Drugs & Pharmacology Authors: Yong Li Xu-Lin He Li-Ping Zhou Xiao-Zhong Huang Shan Li Su Guan Jing Li Lei Zhang Source Type: research
Asiatic acid alleviates liver fibrosis via multiple signaling pathways based on integrated network pharmacology and lipidomics
Eur J Pharmacol. 2022 Aug 10:175193. doi: 10.1016/j.ejphar.2022.175193. Online ahead of print.ABSTRACTLiver fibrosis is characterized by the abnormal deposition of the extracellular matrix with a severe inflammatory response and/or metabolic disorder. Asiatic acid (AA), a natural compound derived from Centella asiatica, exhibited potent anti-fibrosis effects. This investigation first confirmed the anti-fibrosis effects of AA in TGF-β-LX-2 cells and CCl4-induced liver fibrosis mice, and then sought to elucidate a novel mechanism of action by integrating network pharmacology and lipidomics. Network pharmacology was used to ...
Source: European Journal of Pharmacology - August 13, 2022 Category: Drugs & Pharmacology Authors: Yong Li Xu-Lin He Li-Ping Zhou Xiao-Zhong Huang Shan Li Su Guan Jing Li Lei Zhang Source Type: research
Counteracting side effects of combined oral contraceptives through the administration of specific micronutrients
CONCLUSIONS: Considering the wide use of OCs, taking appropriate dietary supplements could be an effective approach in clinical practice, tailoring therapies and improving both safety and tolerability.PMID:35856377 | DOI:10.26355/eurrev_202207_29210 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - July 20, 2022 Category: Drugs & Pharmacology Authors: S Basciani G Porcaro Source Type: research
Counteracting side effects of combined oral contraceptives through the administration of specific micronutrients
CONCLUSIONS: Considering the wide use of OCs, taking appropriate dietary supplements could be an effective approach in clinical practice, tailoring therapies and improving both safety and tolerability.PMID:35856377 | DOI:10.26355/eurrev_202207_29210 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - July 20, 2022 Category: Drugs & Pharmacology Authors: S Basciani G Porcaro Source Type: research
