Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
Standardized Extract of < em > Centella asiatica < /em > Prevents Fear Memory Deficit in 3xTg-AD Mice
In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi a...
Source: The American Journal of Chinese Medicine - January 25, 2023 Category: Complementary Medicine Authors: Tanita Pairojana Sarayut Phasuk Mayuree H Tantisira Kai-Chi Liang Sittiruk Roytrakul Narawut Pakaprot Supin Chompoopong Sutisa Nudmamud-Thanoi Yang Ming Ingrid Y Liu Source Type: research
