Therapeutic Implications of Some Natural Products for Neuroimmune Diseases: A Narrative of Clinical Studies Review
Evid Based Complement Alternat Med. 2023 Apr 13;2023:5583996. doi: 10.1155/2023/5583996. eCollection 2023.ABSTRACTNeuroimmune diseases are a group of disorders that occur due to the dysregulation of both the nervous and immune systems, and these illnesses impact tens of millions of people worldwide. However, patients who suffer from these debilitating conditions have very few FDA-approved treatment options. Neuroimmune crosstalk is important for controlling the immune system both centrally and peripherally to maintain tissue homeostasis. This review aims to provide readers with information on how natural products modulate ...
Source: Evidence-based Complementary and Alternative Medicine - April 24, 2023 Category: Complementary Medicine Authors: Gayathri Wijeweera Nalaka Wijekoon Lakmal Gonawala Yoonus Imran Chandra Mohan K Ranil D De Silva Source Type: research
Evaluation of Anti- < em > Candida albicans < /em > Activities of Herbal Preparations Sold at the Kumasi Central Market in the Ashanti Region of Ghana
This study, therefore, evaluated the anti-C. albicans activities of five selected herbal preparations indicated for treating candidiasis sold at the Kumasi Central Market in the Ashanti Region of Ghana. The market was divided into five clusters, and one herbal preparation was randomly selected from each cluster. Using the Kirby Bauer disc diffusion antimicrobial susceptibility test, the herbal preparations were tested against clinically isolated C. albicans. Fluconazole, a standard antifungal drug, was included in the evaluation as a positive control. The experiments were performed on three different days and each in tripl...
Source: Evidence-based Complementary and Alternative Medicine - April 21, 2023 Category: Complementary Medicine Authors: Seth A Domfeh Godfred Kyeremeh Mark Belifini Source Type: research
The Zebrafish Model as a New Discovery Path for Medicinal Plants in the Treatment of Parkinson's Disease
CNS Neurol Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871527322666230330111712. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most frequent degenerative central nervous system disorders affecting older adults. Dopaminergic neuron failure in the substantia nigra is a pathological sign connected with the motor shortfall of PD. Due to their low teratogenic and adverse effect potential, medicinal herbs have emerged as a promising therapy option for preventing and curing PD and other neurodegenerative disorders. However, the mechanism through which natural compounds provide neuroprotection against PD...
Source: CNS and Neurological Disorders Drug Targets - March 31, 2023 Category: Drugs & Pharmacology Authors: Amir Modarresi Chahardehi Yasaman Hosseini Seyed Mohammad Mahdavi Iman Naseh Source Type: research
The Zebrafish Model as a New Discovery Path for Medicinal Plants in the Treatment of Parkinson's Disease
CNS Neurol Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871527322666230330111712. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most frequent degenerative central nervous system disorders affecting older adults. Dopaminergic neuron failure in the substantia nigra is a pathological sign connected with the motor shortfall of PD. Due to their low teratogenic and adverse effect potential, medicinal herbs have emerged as a promising therapy option for preventing and curing PD and other neurodegenerative disorders. However, the mechanism through which natural compounds provide neuroprotection against PD...
Source: CNS and Neurological Disorders Drug Targets - March 31, 2023 Category: Drugs & Pharmacology Authors: Amir Modarresi Chahardehi Yasaman Hosseini Seyed Mohammad Mahdavi Iman Naseh Source Type: research
The Zebrafish Model as a New Discovery Path for Medicinal Plants in the Treatment of Parkinson's Disease
CNS Neurol Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871527322666230330111712. Online ahead of print.ABSTRACTParkinson's disease (PD) is one of the most frequent degenerative central nervous system disorders affecting older adults. Dopaminergic neuron failure in the substantia nigra is a pathological sign connected with the motor shortfall of PD. Due to their low teratogenic and adverse effect potential, medicinal herbs have emerged as a promising therapy option for preventing and curing PD and other neurodegenerative disorders. However, the mechanism through which natural compounds provide neuroprotection against PD...
Source: CNS and Neurological Disorders Drug Targets - March 31, 2023 Category: Drugs & Pharmacology Authors: Amir Modarresi Chahardehi Yasaman Hosseini Seyed Mohammad Mahdavi Iman Naseh Source Type: research
The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery
To evaluate the efficacy of the Centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release (CTR) surgery. (Source: Journal of Hand Therapy)
Source: Journal of Hand Therapy - March 12, 2023 Category: Rehabilitation Authors: Mustafa Balevi, Ali Balevi Source Type: research
Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment
Ultrason Sonochem. 2023 Mar 4;94:106353. doi: 10.1016/j.ultsonch.2023.106353. Online ahead of print.ABSTRACTCentella asiatica possess various health-promoting activities owing to its bioactive compounds such as triterpenes, flavonoids, and vitamins. Ultrasound treatment during the post-harvest process is a good strategy for eliciting secondary metabolite in plants. The present study investigated the effect of ultrasound treatment for different time durations on the bioactive compounds and biological activities of C. asiatica leaves. The leaves were treated with ultrasound for 5, 10, and 20 min. Ultrasound elicitation (espe...
Source: Ultrasonics Sonochemistry - March 8, 2023 Category: Chemistry Authors: Eunjeong Seong Huijin Heo Heon Sang Jeong Hana Lee Junsoo Lee Source Type: research
Enhancement of bioactive compounds and biological activities of Centella asiatica through ultrasound treatment
Ultrason Sonochem. 2023 Mar 4;94:106353. doi: 10.1016/j.ultsonch.2023.106353. Online ahead of print.ABSTRACTCentella asiatica possess various health-promoting activities owing to its bioactive compounds such as triterpenes, flavonoids, and vitamins. Ultrasound treatment during the post-harvest process is a good strategy for eliciting secondary metabolite in plants. The present study investigated the effect of ultrasound treatment for different time durations on the bioactive compounds and biological activities of C. asiatica leaves. The leaves were treated with ultrasound for 5, 10, and 20 min. Ultrasound elicitation (espe...
Source: Ultrasonics Sonochemistry - March 8, 2023 Category: Chemistry Authors: Eunjeong Seong Huijin Heo Heon Sang Jeong Hana Lee Junsoo Lee Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Current Issues in Molecular Biology - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
Advances in Molecular Regulation of Prostate Cancer Cells by Top Natural Products of Malaysia
We present a review of the molecular targets driving current drug discovery to fight this disease. Moreover, the preventable nature of most PCa cases represents an opportunity for phytochemicals as chemopreventive when adequately integrated into nutritional interventions. With a renovated interest in natural remedies as a commodity and their essential role in cancer drug discovery, Malaysia is looking towards capitalizing on its mega biodiversity, which includes the oldest rainforest in the world and an estimated 1200 medicinal plants. We here explore whether the list of top Malay plants prioritized by the Malaysian govern...
Source: Mol Biol Cell - February 24, 2023 Category: Molecular Biology Authors: Jose M Prieto Mohd Mukrish Mohd Hanafi Source Type: research
