A Bottom-up Proteomics Workflow for a System Containing Multiple Organisms
CONCLUSION: A proteomics protocol is detailed for a system containing multiple proteomes from different taxonomic lineages using cat-flea-Barttonella as an example. The operating protocol can be readily applied to other label-free proteomics work involving multiple proteomes from taxonomically distinct organisms.PMID:36422865 | DOI:10.1002/rcm.9431 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - November 24, 2022 Category: Chemistry Authors: Hongxia Bai Leonard B Collins Marcos Rog ério André Edward B Breitschwerdt Taufika Islam Williams Source Type: research

A Bottom-up Proteomics Workflow for a System Containing Multiple Organisms
CONCLUSION: A proteomics protocol is detailed for a system containing multiple proteomes from different taxonomic lineages using cat-flea-Barttonella as an example. The operating protocol can be readily applied to other label-free proteomics work involving multiple proteomes from taxonomically distinct organisms.PMID:36422865 | DOI:10.1002/rcm.9431 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - November 24, 2022 Category: Chemistry Authors: Hongxia Bai Leonard B Collins Marcos Rog ério André Edward B Breitschwerdt Taufika Islam Williams Source Type: research

In silico analyses and design of chimeric proteins containing epitopes of Bartonella henselae antigens for the control of cat scratch disease
Appl Microbiol Biotechnol. 2022 Nov 16. doi: 10.1007/s00253-022-12269-3. Online ahead of print.ABSTRACTBartonella henselae is a Gram-negative bacterium that causes cat scratch disease (CSD), as well as bacteremia, endocarditis, and other clinical presentations. CSD remains one of the most common infections caused by bacteria in the genus Bartonella, and it is transmitted to humans through a scratch or cat bite. Vaccination and more efficient diagnostic methods would represent a promising and sustainable alternative measure for CSD control in humans and animals. Here, we described the in silico analyses and design of three ...
Source: Applied Microbiology and Biotechnology - November 16, 2022 Category: Microbiology Authors: J ênifer Malheiros Gonçalves Thayn á Laner Cardoso Stella Buchhorn de Freitas Rafael Woloski Amilton Clair Pinto Seixas Neto Luciano da Silva Pinto Elba Sampaio de Lemos Daiane Drawanz Hartwig Source Type: research

In silico analyses and design of chimeric proteins containing epitopes of Bartonella henselae antigens for the control of cat scratch disease
Appl Microbiol Biotechnol. 2022 Nov 16. doi: 10.1007/s00253-022-12269-3. Online ahead of print.ABSTRACTBartonella henselae is a Gram-negative bacterium that causes cat scratch disease (CSD), as well as bacteremia, endocarditis, and other clinical presentations. CSD remains one of the most common infections caused by bacteria in the genus Bartonella, and it is transmitted to humans through a scratch or cat bite. Vaccination and more efficient diagnostic methods would represent a promising and sustainable alternative measure for CSD control in humans and animals. Here, we described the in silico analyses and design of three ...
Source: Applied Microbiology and Biotechnology - November 16, 2022 Category: Microbiology Authors: J ênifer Malheiros Gonçalves Thayn á Laner Cardoso Stella Buchhorn de Freitas Rafael Woloski Amilton Clair Pinto Seixas Neto Luciano da Silva Pinto Elba Sampaio de Lemos Daiane Drawanz Hartwig Source Type: research

A case of < em > Bartonellosis < /em > mimicking systemic lupus erythematosus
CONCLUSION: Further research is warranted in order to determine the dose and duration of CSs in the treatment of Bartonella neuroretinitis.PMID:36345218 | DOI:10.1177/11206721221137163 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - November 8, 2022 Category: Opthalmology Authors: Manolya Kara Gul Nihal Ozdemir Mehmet Tasdemir Serap Ata Belma Karini Eldar Valiyev Ilknur Tugal Tutkun Gulsen Kose Ozan Ozkaya Source Type: research

Multi-locus Sequencing Typing of Bartonella henselae isolates reveals coinfection with different variants in domestic cats from Midwestern Brazil
Acta Trop. 2022 Nov 2:106742. doi: 10.1016/j.actatropica.2022.106742. Online ahead of print.ABSTRACTBartonella henselae is a zoonotic pathogen responsible for causing Cat Scratch Disease (CSD) and other clinical manifestations in humans. Domestic cats are the main reservoirs of this Bartonella species. Previous studies have suggested that certain genotypes of B. henselae seem to be more associated with human infections. The present study aimed to genotype B. henselae isolates from domestic cats' blood samples in the state of Goiás, midwestern Brazil. The association of quantitative real-time PCR (qPCR) based on the nuoG g...
Source: Acta Tropica - November 5, 2022 Category: Infectious Diseases Authors: Clara Morato Dias Renan Bressianini do Amaral L ívia Perles Ant ônia Laila Dos Santos Muniz Tarik Fernandes Gon çalves Rocha Rosangela Zacarias Machado Marcos Rog ério André Source Type: research

Multi-locus Sequencing Typing of Bartonella henselae isolates reveals coinfection with different variants in domestic cats from Midwestern Brazil
Acta Trop. 2022 Nov 2:106742. doi: 10.1016/j.actatropica.2022.106742. Online ahead of print.ABSTRACTBartonella henselae is a zoonotic pathogen responsible for causing Cat Scratch Disease (CSD) and other clinical manifestations in humans. Domestic cats are the main reservoirs of this Bartonella species. Previous studies have suggested that certain genotypes of B. henselae seem to be more associated with human infections. The present study aimed to genotype B. henselae isolates from domestic cats' blood samples in the state of Goiás, midwestern Brazil. The association of quantitative real-time PCR (qPCR) based on the nuoG g...
Source: Acta Tropica - November 5, 2022 Category: Infectious Diseases Authors: Clara Morato Dias Renan Bressianini do Amaral L ívia Perles Ant ônia Laila Dos Santos Muniz Tarik Fernandes Gon çalves Rocha Rosangela Zacarias Machado Marcos Rog ério André Source Type: research

Purulent lymphadenitis due to Halomonas hamiltonii: a case report
The Genus Halomonas comprises halophilic and alkaliphilic gram-negative rods isolated from high-salt environments and belongs to the class Gammaproteobacteria. Halomonas hamiltonii was reported to be pathogenic in humans in 2009, causing bloodstream infection in patients on dialysis (Stevens et al., 2009). Axillary lymph nodes drain lymph fluid from the superficial lymph vessels in the hands, arms, breasts, chest, and abdomen above the umbilicus. When children present with swollen and tender axillary lymph nodes; cat-scratch disease; or arm or chest wall infection malignancy of the chest wall, leukemia, lymphoma, and bruce...
Source: International Journal of Infectious Diseases - October 28, 2022 Category: Infectious Diseases Authors: Yoji Uejima, Tsutomu Oh-Ishi, Isao Kitajima, Hideki Niimi Tags: Case Report Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research

Serological review of Bartonella henselae and Bartonella quintana infection among Malaysian patients with unknown causes of febrile illnesses
This study reports a review of serological findings obtained from patients attending to a teaching hospital in Klang Valley, Malaysia. An indirect immunofluorescence assay (IFA) was used to determine IgG and IgM antibody titers against B. henselae and B. quintana. In a pilot study conducted between 2013-2015, IgG antibodies against Bartonella spp. (either B. quintana and B. henselae) were detected in 14 (36.8%) of 38 patients who were clinically suspected of rickettsial infections, while IgM antibody was detected in 4 (10.5%) patients. This has prompted us to investigate the serologic responses of patients who were clinica...
Source: Tropical Biomedicine - October 10, 2022 Category: Tropical Medicine Authors: S L Hou N Idris S T Tay Source Type: research