An Update on Treatment Modalities for Ulnar Nerve Entrapment: A Literature Review
CONCLUSIONS: Clinical diagnosis of ulnar nerve entrapment can often be delayed and requires the suspicion as well as a thorough neurological exam. Early recognition and diagnois are important for early institution of treatment. A wide array of diagnostic imaging can be useful in ruling out bony, soft tissue, or vascular etiologies, respectively. However, clinicians should resort to electrodiagnostic testing when a definitive diagnois is needed. Many new minimally invasive techniques are in the literature and show great promise; however, further large scale trials are needed to validate these techniques. Surgical options re...
Source: Pain Physician - June 21, 2021 Category: Anesthesiology Authors: Neeraj Vij Blake Traube Roy Bisht Ian Singleton Elyse M Cornett Alan D Kaye Farnad Imani Ali Mohammadian Erdi Giustino Varrassi Omar Viswanath Ivan Urits Source Type: research

Carpal Tunnel Release Surgery- A Systematic Review of Open and Endoscopic Approaches
CONCLUSIONS: ECTR and OCTR produce satisfactory results in pain relief, symptom resolution, patient satisfaction, time to return to work, and adverse events. There is a growing body of evidence favoring the endoscopic technique for pain relief, functional outcomes, and satisfaction, at least in the early post-operative period, even if this difference disappears over time. Several studies have demonstrated a quicker return to work and activities of daily living with the endoscopic technique.PMID:34150584 | PMC:PMC8207842 | DOI:10.5812/aapm.112291 (Source: Pain Physician)
Source: Pain Physician - June 21, 2021 Category: Anesthesiology Authors: Vwaire Orhurhu Sebastian Orman Jacquelin Peck Ivan Urits Mariam Salisu Orhurhu Mark R Jones Laxmaiah Manchikanti Alan D Kaye Charles Odonkor Sameer Hirji Elyse M Cornett Farnad Imani Giustino Varrassi Omar Viswanath Source Type: research

Rates of and Risk Factors for Trigger Finger after Open Carpal Tunnel Release
J Wrist Surg DOI: 10.1055/s-0041-1730343 Background We have anecdotally noticed a higher rate of trigger fingers (TFs) developing in patients who have undergone carpal tunnel release (CTR). Questions/Objective Is the rate of TFs after CTR greater compared to the nonoperative hand? Is the thumb more commonly involved postoperatively compared with spontaneous TFs? Do particular associated comorbidities increase this risk? Patients and Methods We queried our institutional database for patients who had undergone open CTR during a 2-year period and recorded the development of an ipsilateral TF after a CT...
Source: Journal of Wrist Surgery - June 21, 2021 Category: Orthopaedics Authors: Raducha, Jeremy E. Jiang, Winston Kahan, Lindsey Dove, James Houston Cochran, Christopher Weiss, Arnold-Peter C. Tags: Scientific Article Source Type: research

Median nerve compression in the carpal tunnel in children  - a delayed diagnosis. About 20 clinical cases
CONCLUSION: The diagnosis of carpal tunnel syndrome is difficult in children. It is common to be confronted with an advanced clinical symptoms. The atypical symptoms may cause diagnostic delay. Due to the quality of the clinical results obtained, we recommend open carpal tunnel release even when the diagnosis seems delayed.LEVEL OF EVIDENCE: IV.PMID:34144846 | DOI:10.1016/j.anplas.2021.04.003 (Source: Annales de Chirurgie Plastique et Esthetique)
Source: Annales de Chirurgie Plastique et Esthetique - June 19, 2021 Category: Cosmetic Surgery Authors: E Andre A Hamel P Perrot F Duteille Source Type: research

Median nerve compression in the carpal tunnel in children  - a delayed diagnosis. About 20 clinical cases
CONCLUSION: The diagnosis of carpal tunnel syndrome is difficult in children. It is common to be confronted with an advanced clinical symptoms. The atypical symptoms may cause diagnostic delay. Due to the quality of the clinical results obtained, we recommend open carpal tunnel release even when the diagnosis seems delayed.LEVEL OF EVIDENCE: IV.PMID:34144846 | DOI:10.1016/j.anplas.2021.04.003 (Source: Annales de Chirurgie)
Source: Annales de Chirurgie - June 19, 2021 Category: Surgery Authors: E Andre A Hamel P Perrot F Duteille Source Type: research

Median nerve compression in the carpal tunnel in children  - a delayed diagnosis. About 20 clinical cases
CONCLUSION: The diagnosis of carpal tunnel syndrome is difficult in children. It is common to be confronted with an advanced clinical symptoms. The atypical symptoms may cause diagnostic delay. Due to the quality of the clinical results obtained, we recommend open carpal tunnel release even when the diagnosis seems delayed.LEVEL OF EVIDENCE: IV.PMID:34144846 | DOI:10.1016/j.anplas.2021.04.003 (Source: Annales de Chirurgie Plastique et Esthetique)
Source: Annales de Chirurgie Plastique et Esthetique - June 19, 2021 Category: Cosmetic Surgery Authors: E Andre A Hamel P Perrot F Duteille Source Type: research

Median nerve compression in the carpal tunnel in children  - a delayed diagnosis. About 20 clinical cases
CONCLUSION: The diagnosis of carpal tunnel syndrome is difficult in children. It is common to be confronted with an advanced clinical symptoms. The atypical symptoms may cause diagnostic delay. Due to the quality of the clinical results obtained, we recommend open carpal tunnel release even when the diagnosis seems delayed.LEVEL OF EVIDENCE: IV.PMID:34144846 | DOI:10.1016/j.anplas.2021.04.003 (Source: Annales de Chirurgie)
Source: Annales de Chirurgie - June 19, 2021 Category: Surgery Authors: E Andre A Hamel P Perrot F Duteille Source Type: research

Diagnosis of wild ‐type transthyretin amyloid cardiomyopathy in Japan: red‐flag symptom clusters and diagnostic algorithm
AbstractWild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is caused by the deposition of wild-type transthyretin (TTR) amyloid fibrils in the heart. The age at diagnosis of ATTRwt-CM is reported to be approximately 70 –80 years, and patients commonly present with non-disease-specific cardiac abnormalities, such as heart failure with preserved ejection fraction and diastolic dysfunction. The disease can be fatal if left untreated, with an approximate survival of 3–5 years from diagnosis. An oral TTR stabiliz er, tafamidis, has enabled early intervention for the treatment of ATTRwt-CM. However,...
Source: ESC Heart Failure - June 17, 2021 Category: Cardiology Authors: Takayuki Inomata, Nobuhiro Tahara, Kazufumi Nakamura, Jin Endo, Mitsuharu Ueda, Tomonori Ishii, Yoshinobu Kitano, Jun Koyama Tags: Review Source Type: research

Anatomical work-up of an individual with multiple muscular variants on both forearms
AbstractMuscular variants of the forearm are common and frequently cause neurovascular compression syndromes, especially when interfering with the compact topography of the carpal tunnel or the Canalis ulnaris. Here, we report on a male body donor with multiple muscular normal variations on both forearms. The two main findings are (1) an accessory variant muscle (AVM) on the right forearm originating from theM. brachioradialis, the distal radius, and theM. flexor pollicis longus. It spanned the wrist beneath theFascia antebrachia and inserted at the proximal phalanx of thedigitus minimus. (2) Moreover, we found a three-hea...
Source: Anatomical Science International - June 16, 2021 Category: Anatomy Source Type: research

Minimally invasive carpal tunnel decompression using the KnifeLight: How I Do It
ConclusionThis is a simple, efficient, and reproducible alternative for carpal tunnel decompression. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - June 12, 2021 Category: Neurosurgery Source Type: research

Transient Proximal Median Nerve Entrapment in a Tetraplegic Hand Cyclist Following a 24-Hour Endurance Race
Mil Med. 2021 Jun 11:usab226. doi: 10.1093/milmed/usab226. Online ahead of print.ABSTRACTMedian nerve entrapment is a frequent disorder encountered by all clinicians at some point of their career. Affecting the distal median nerve, entrapment occurs most frequently at the level of the wrist resulting in a carpal tunnel syndrome. Median nerve entrapment may also occur proximally giving rise to the much less frequent pronator teres syndrome and even less frequent anterior interosseous nerve syndrome, which owing to the paucity of cases may prove challenging to diagnose. An unusual case of anterior interosseous syndrome preci...
Source: Military Medicine - June 11, 2021 Category: International Medicine & Public Health Authors: S øren Bruno Elmgreen Source Type: research

Structural white matter alterations in carpal tunnel syndrome: A modified TBSS study
In this study, 25 moderate/severe CTS patients and 17 age- and sex-matched healthy controls (HC) were evaluated with DTI. Fractional anisotropy (FA) and radial diffusivity (RD) were calculated for group comparison. And the relationship between diffusion parameters and clinical assessments was also analyzed. Comparing with the healthy controls, CTS patients showed significantly increased FA and decreased RD in areas of multisensory integration and motor control involving the central opercular cortex and supplementary motor area (SMA) of the dominant hemisphere. Moreover, altered diffusion parameters in the central opercular...
Source: Brain Research - June 11, 2021 Category: Neurology Authors: Xin Xue Jia-Jia Wu Xu-Yun Hua Mou-Xiong Zheng Jie Ma Zhen-Zhen Ma Yu-Lin Li Chun-Lei Shan Jian-Guang Xu Source Type: research

Trigger finger in children with hurler syndrome - distribution pattern and treatment options
Conclusion: The treatment of trigger fingers in children with mucopolysaccharidosis as a rare disease is challenging with regard to diagnostics and indication. The main treatment goal is pain relief and improvement of hand function.PMID:34113532 | PMC:PMC8167262 | DOI:10.3205/iprs000154 (Source: Hand Surgery)
Source: Hand Surgery - June 11, 2021 Category: Surgery Authors: Andreas Jokuszies Lorenz Grigull Tobias Mett Khaled Dastagir Alperen Bingoel Peter M Vogt Source Type: research

Transient Proximal Median Nerve Entrapment in a Tetraplegic Hand Cyclist Following a 24-Hour Endurance Race
Mil Med. 2021 Jun 11:usab226. doi: 10.1093/milmed/usab226. Online ahead of print.ABSTRACTMedian nerve entrapment is a frequent disorder encountered by all clinicians at some point of their career. Affecting the distal median nerve, entrapment occurs most frequently at the level of the wrist resulting in a carpal tunnel syndrome. Median nerve entrapment may also occur proximally giving rise to the much less frequent pronator teres syndrome and even less frequent anterior interosseous nerve syndrome, which owing to the paucity of cases may prove challenging to diagnose. An unusual case of anterior interosseous syndrome preci...
Source: Military Medicine - June 11, 2021 Category: International Medicine & Public Health Authors: S øren Bruno Elmgreen Source Type: research

Structural white matter alterations in carpal tunnel syndrome: A modified TBSS study
In this study, 25 moderate/severe CTS patients and 17 age- and sex-matched healthy controls (HC) were evaluated with DTI. Fractional anisotropy (FA) and radial diffusivity (RD) were calculated for group comparison. And the relationship between diffusion parameters and clinical assessments was also analyzed. Comparing with the healthy controls, CTS patients showed significantly increased FA and decreased RD in areas of multisensory integration and motor control involving the central opercular cortex and supplementary motor area (SMA) of the dominant hemisphere. Moreover, altered diffusion parameters in the central opercular...
Source: Brain Research - June 11, 2021 Category: Neurology Authors: Xin Xue Jia-Jia Wu Xu-Yun Hua Mou-Xiong Zheng Jie Ma Zhen-Zhen Ma Yu-Lin Li Chun-Lei Shan Jian-Guang Xu Source Type: research

Palmar fracture-dislocation of the trapezoid with median nerve contusion. Case report and literature review
Case Reports Plast Surg Hand Surg. 2021 May 19;8(1):76-80. doi: 10.1080/23320885.2021.1927739.ABSTRACTComplete dislocations of the trapezoid are very uncommon injuries. The authors present a case of open palmar trapezoid fracture-dislocation with significant displacement of the fracture, acute carpal tunnel syndrome and other concomitant carpometacarpal injuries. A review of the literature search for palmar trapezoid dislocations and treatments was performed.PMID:34104673 | PMC:PMC8143597 | DOI:10.1080/23320885.2021.1927739 (Source: Hand Surgery)
Source: Hand Surgery - June 9, 2021 Category: Surgery Authors: Sara Montanari Leone Pangallo Annalisa Valore Roberto Adani Source Type: research

Does Patient Sex Affect Ultrasound Cutoff Values for Severity Grading of Carpal Tunnel Syndrome?
CONCLUSIONS: Patient sex does not appear to have a significant impact on the determination of CTS severity graded using US cutoff values. Ultrasound can be used to grade the severity of CTS with a 75% to 85% specificity but low sensitivity. A cutoff value of 13 mm2 can be used to classify CTS as severe.TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.PMID:34103184 | DOI:10.1016/j.jhsa.2021.04.022 (Source: Hand Surgery)
Source: Hand Surgery - June 9, 2021 Category: Surgery Authors: Emily Hacker Robert J Goitz John R Fowler Source Type: research

Does Patient Sex Affect Ultrasound Cutoff Values for Severity Grading of Carpal Tunnel Syndrome?
CONCLUSIONS: Patient sex does not appear to have a significant impact on the determination of CTS severity graded using US cutoff values. Ultrasound can be used to grade the severity of CTS with a 75% to 85% specificity but low sensitivity. A cutoff value of 13 mm2 can be used to classify CTS as severe.TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.PMID:34103184 | DOI:10.1016/j.jhsa.2021.04.022 (Source: Hand Surgery)
Source: Hand Surgery - June 9, 2021 Category: Surgery Authors: Emily Hacker Robert J Goitz John R Fowler Source Type: research

Palmar fracture-dislocation of the trapezoid with median nerve contusion. Case report and literature review
Case Reports Plast Surg Hand Surg. 2021 May 19;8(1):76-80. doi: 10.1080/23320885.2021.1927739.ABSTRACTComplete dislocations of the trapezoid are very uncommon injuries. The authors present a case of open palmar trapezoid fracture-dislocation with significant displacement of the fracture, acute carpal tunnel syndrome and other concomitant carpometacarpal injuries. A review of the literature search for palmar trapezoid dislocations and treatments was performed.PMID:34104673 | PMC:PMC8143597 | DOI:10.1080/23320885.2021.1927739 (Source: Hand Surgery)
Source: Hand Surgery - June 9, 2021 Category: Surgery Authors: Sara Montanari Leone Pangallo Annalisa Valore Roberto Adani Source Type: research

Ultrasound-guided local corticosteroid injection for carpal tunnel syndrome: A meta-analysis of randomized controlled trials
Clin Rehabil. 2021 Jun 6:2692155211014702. doi: 10.1177/02692155211014702. Online ahead of print.ABSTRACTOBJECTIVE: This meta-analysis aimed to compare the efficacy and safety of ultrasound-guided (US-guided) versus landmark-guided (LM-guided) local corticosteroid injection for carpal tunnel syndrome (CTS).METHODS: Database including Pubmed, Embase, and Cochrane Library were searched to identify relevant randomized controlled trials (RCTs). The outcomes mainly included Boston Carpal Tunnel Questionnaire (BCTQ): Symptom Severity Scale (BCTQs), Functional Status Scale (BCTQf); and electrophysiological indexes: distal motor l...
Source: Clinical Rehabilitation - June 7, 2021 Category: Rehabilitation Authors: Hongchen Wang Yuting Zhu Hongyu Wei Chunke Dong Source Type: research

Ultrasound-guided local corticosteroid injection for carpal tunnel syndrome: A meta-analysis of randomized controlled trials
Clin Rehabil. 2021 Jun 6:2692155211014702. doi: 10.1177/02692155211014702. Online ahead of print.ABSTRACTOBJECTIVE: This meta-analysis aimed to compare the efficacy and safety of ultrasound-guided (US-guided) versus landmark-guided (LM-guided) local corticosteroid injection for carpal tunnel syndrome (CTS).METHODS: Database including Pubmed, Embase, and Cochrane Library were searched to identify relevant randomized controlled trials (RCTs). The outcomes mainly included Boston Carpal Tunnel Questionnaire (BCTQ): Symptom Severity Scale (BCTQs), Functional Status Scale (BCTQf); and electrophysiological indexes: distal motor l...
Source: Clinical Rehabilitation - June 7, 2021 Category: Rehabilitation Authors: Hongchen Wang Yuting Zhu Hongyu Wei Chunke Dong Source Type: research

Does Patient Sex Affect Ultrasound Cutoff Values for Severity Grading of Carpal Tunnel Syndrome?
A growing body of evidence supports ultrasound (US) as an alternative first-line confirmatory test for carpal tunnel syndrome (CTS). Recent studies have demonstrated a correlation of US cross-sectional area with electrodiagnostic (EDX)-determined severity; however, it is unclear whether patient sex affects the cutoff values used for determining severity. The purpose of this study was to determine if patient sex affects US graded severity when using EDX as the reference standard. (Source: The Journal of Hand Surgery)
Source: The Journal of Hand Surgery - June 5, 2021 Category: Surgery Authors: Emily Hacker, Robert J. Goitz, John R. Fowler Tags: Editor ’s Choice Source Type: research

Multidisciplinary Approaches for Transthyretin Amyloidosis
AbstractAmyloidosis caused by systemic deposition of transthyretin (TTR) is called ATTR amyloidosis and mainly includes hereditary ATTR (ATTRv) amyloidosis and wild-type ATTR (ATTRwt) amyloidosis. Until recently, ATTRv amyloidosis had been considered a disease in the field of neurology because neuropathic symptoms predominated in patients described in early reports, whereas advances in diagnostic techniques and increased recognition of this disease revealed the presence of patients with cardiomyopathy as a predominant feature. In contrast, ATTRwt amyloidosis has been considered a disease in the field of cardiology. However...
Source: Cardiology and Therapy - June 4, 2021 Category: Cardiology Source Type: research

A new clinically-relevant rat model of letrozole-induced chronic nociceptive disorders
Toxicol Appl Pharmacol. 2021 May 31:115600. doi: 10.1016/j.taap.2021.115600. Online ahead of print.ABSTRACTAmong postmenopausal women with estrogen receptor-positive breast cancer, more than 80% receive hormone therapy including aromatase inhibitors (AIs). Half of them develop chronic arthralgia - characterized by symmetric articular pain, carpal tunnel syndrome, morning stiffness, myalgia and a decrease in grip strength - which is associated with treatment discontinuation. Only a few animal studies have linked AI treatment to nociception, and none to arthralgia. Thus, we developed a new chronic AI-induced nociceptive diso...
Source: Toxicology and Applied Pharmacology - June 3, 2021 Category: Toxicology Authors: Aurore Collin Julie Vein Yohann Wittrant Bruno Pereira Raalib Amode Christelle Guillet Damien Richard Alain Eschalier David Balayssac Source Type: research

A new clinically-relevant rat model of letrozole-induced chronic nociceptive disorders
Toxicol Appl Pharmacol. 2021 May 31:115600. doi: 10.1016/j.taap.2021.115600. Online ahead of print.ABSTRACTAmong postmenopausal women with estrogen receptor-positive breast cancer, more than 80% receive hormone therapy including aromatase inhibitors (AIs). Half of them develop chronic arthralgia - characterized by symmetric articular pain, carpal tunnel syndrome, morning stiffness, myalgia and a decrease in grip strength - which is associated with treatment discontinuation. Only a few animal studies have linked AI treatment to nociception, and none to arthralgia. Thus, we developed a new chronic AI-induced nociceptive diso...
Source: Toxicology and Applied Pharmacology - June 3, 2021 Category: Toxicology Authors: Aurore Collin Julie Vein Yohann Wittrant Bruno Pereira Raalib Amode Christelle Guillet Damien Richard Alain Eschalier David Balayssac Source Type: research

The Epidemiology of Carpal Tunnel Revision Over a 1-Year Follow-Up Period
CONCLUSIONS: This study identified a rate of revision CTR of 4.8% within the first postoperative year. Both the surgical technique and patient-specific risk factors influence the likelihood of requiring revision surgery. Notably, an endoscopic approach is associated with a higher risk of revision surgery.TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.PMID:34059387 | DOI:10.1016/j.jhsa.2021.04.003 (Source: Hand Surgery)
Source: Hand Surgery - June 1, 2021 Category: Surgery Authors: Lauren E Wessel Alex Gu Paul A Asadourian Jeffrey G Stepan Duretti T Fufa Daniel A Osei Source Type: research

The Epidemiology of Carpal Tunnel Revision Over a 1-Year Follow-Up Period
CONCLUSIONS: This study identified a rate of revision CTR of 4.8% within the first postoperative year. Both the surgical technique and patient-specific risk factors influence the likelihood of requiring revision surgery. Notably, an endoscopic approach is associated with a higher risk of revision surgery.TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.PMID:34059387 | DOI:10.1016/j.jhsa.2021.04.003 (Source: Hand Surgery)
Source: Hand Surgery - June 1, 2021 Category: Surgery Authors: Lauren E Wessel Alex Gu Paul A Asadourian Jeffrey G Stepan Duretti T Fufa Daniel A Osei Source Type: research

Median Nerve’s Microcirculation in Carpal Tunnel Syndrome: Superb Microvascular Imaging
Conclusions: Superb microvascular imaging is emerging as a groundbreaking, new, and reliable technique. Evaluation of the median nerve blood supply is a reliable method that would be helpful for early diagnosis, planning treatment, determining the severity of carpal tunnel syndrome, and postoperative follow-up. CLINICAL QUESTION/LEVEL OF EVIDENCE: Diagnostic, IV. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - June 1, 2021 Category: Cosmetic Surgery Tags: Hand/Peripheral Nerve: Original Articles Source Type: research

Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity
ConclusionsOur results indicate that obesity causally affects a wide range of traits and comorbid diseases, thus providing an overview of the metabolic, physiological, and neuropsychiatric impact of obesity on human health. (Source: Human Genetics)
Source: Human Genetics - May 31, 2021 Category: Genetics & Stem Cells Source Type: research

Hand surgeons and amyloidosis specialists warning: transthyretin-associated amyloidosis with bifid median nerve as a cause of bilateral carpal tunnel syndrome. A case report and literature review
CONCLUSIONS: This case highlights the natural history of the multiple musculoskeletal manifestations related to ATTR and the importance of performing intraoperative biopsies in patients with CTS surgery as this can lead to early diagnosis of cardiac ATTR.PMID:34050818 | DOI:10.1007/s00590-021-03004-1 (Source: Hand Surgery)
Source: Hand Surgery - May 29, 2021 Category: Surgery Authors: Andreu Triguero Jos é González-Costello Silvia L ópez-Marne Alfred Llop Maria Pan é Sergi Yun Source Type: research

Early Outcomes of Endoscopic Versus Open Carpal Tunnel Release
CONCLUSIONS: This study found no evidence suggesting the definitive superiority of 1 surgical technique with regard to clinical outcomes in the early postoperative period. However, OCTR was associated with lower postoperative PROMIS upper-extremity scores of unclear clinical significance, higher odds of remaining on pain medication, and lower odds of returning to work by the first postoperative visit. Endoscopic carpal tunnel release may be preferred in patients who need to return to work within the first 2 weeks after the procedure.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.PMID:34049728 | DOI:10.1016/j.jhsa.2021.04....
Source: Hand Surgery - May 29, 2021 Category: Surgery Authors: Megan R Miles Pragna N Shetty Kovid Bhayana Imran S Yousaf Kavya K Sanghavi Aviram M Giladi Source Type: research

Early Outcomes of Endoscopic Versus Open Carpal Tunnel Release
CONCLUSIONS: This study found no evidence suggesting the definitive superiority of 1 surgical technique with regard to clinical outcomes in the early postoperative period. However, OCTR was associated with lower postoperative PROMIS upper-extremity scores of unclear clinical significance, higher odds of remaining on pain medication, and lower odds of returning to work by the first postoperative visit. Endoscopic carpal tunnel release may be preferred in patients who need to return to work within the first 2 weeks after the procedure.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.PMID:34049728 | DOI:10.1016/j.jhsa.2021.04....
Source: Hand Surgery - May 29, 2021 Category: Surgery Authors: Megan R Miles Pragna N Shetty Kovid Bhayana Imran S Yousaf Kavya K Sanghavi Aviram M Giladi Source Type: research

Hand surgeons and amyloidosis specialists warning: transthyretin-associated amyloidosis with bifid median nerve as a cause of bilateral carpal tunnel syndrome. A case report and literature review
CONCLUSIONS: This case highlights the natural history of the multiple musculoskeletal manifestations related to ATTR and the importance of performing intraoperative biopsies in patients with CTS surgery as this can lead to early diagnosis of cardiac ATTR.PMID:34050818 | DOI:10.1007/s00590-021-03004-1 (Source: Hand Surgery)
Source: Hand Surgery - May 29, 2021 Category: Surgery Authors: Andreu Triguero Jos é González-Costello Silvia L ópez-Marne Alfred Llop Maria Pan é Sergi Yun Source Type: research

Hand surgeons and amyloidosis specialists warning: transthyretin-associated amyloidosis with bifid median nerve as a cause of bilateral carpal tunnel syndrome. A case report and literature review
ConclusionsThis case highlights the natural history of the multiple musculoskeletal manifestations related to ATTR and the importance of performing intraoperative biopsies in patients with CTS surgery as this can lead to early diagnosis of cardiac ATTR. (Source: European Journal of Orthopaedic Surgery and Traumatology)
Source: European Journal of Orthopaedic Surgery and Traumatology - May 29, 2021 Category: Orthopaedics Source Type: research

The Epidemiology of Carpal Tunnel Revision Over a 1-Year Follow-Up Period
To establish the incidence of revision carpal tunnel surgery within a 1-year postoperative period using a national administrative database. This information has been unknown until this point because of the absence of laterality-specific coding with the International Classification of Diseases, Ninth Edition and earlier coding systems. (Source: The Journal of Hand Surgery)
Source: The Journal of Hand Surgery - May 28, 2021 Category: Surgery Authors: Lauren E. Wessel, Alex Gu, Paul A. Asadourian, Jeffrey G. Stepan, Duretti T. Fufa, Daniel A. Osei Tags: Editor ’s Choice Source Type: research

Variant Median Nerve Anatomy: Ultrasound Evidence of a Pseudoconduction Block
Conclusions: This case demonstrates that neuromuscular ultrasound may supplement the electrodiagnostic study and limit confounding technical factors because of rare anatomic variation. (Source: Journal of Clinical Neuromuscular Disease)
Source: Journal of Clinical Neuromuscular Disease - May 27, 2021 Category: Neurology Tags: Case Review Source Type: research

Ultrasound Imaging and Guidance in Common Wrist/Hand Pathologies
Wrist/hand pain is a prevalent musculoskeletal condition with a great spectrum of etiologies (varying from overuse injuries to soft tissue tumors). Although most of the anatomical structures are quite superficial and easily evaluated during physical examination, for several reasons, the use of ultrasound imaging and guidance has gained an intriguing and paramount concern in the prompt management of relevant patients. In this aspect, the present review aims to illustrate detailed cadaveric wrist/hand anatomy to shed light into better understanding the corresponding ultrasonographic examinations/interventions in carpal tunne...
Source: American Journal of Physical Medicine and Rehabilitation - May 27, 2021 Category: Rehabilitation Tags: Literature Review Source Type: research

Opponensplasty by the Palmaris Longus Tendon to the Rerouted Extensor Pollicis Brevis Transfer With Endoscopic Carpal Tunnel Release in Severe Carpal Tunnel Syndrome
This article describes the surgical technique of the opponensplasty using the PL tendon to the rerouted extensor pollicis brevis transfer. The procedure provides satisfactory outcomes for early functional recovery of the hand in patients with severe CTS.PMID:34034945 | DOI:10.1016/j.jhsa.2021.04.007 (Source: Hand Surgery)
Source: Hand Surgery - May 26, 2021 Category: Surgery Authors: Akihiro Hirakawa Shingo Komura Marie Nohara Tomihiro Masuda Yasuharu Matsushita Haruhiko Akiyama Source Type: research

Opponensplasty by the Palmaris Longus Tendon to the Rerouted Extensor Pollicis Brevis Transfer With Endoscopic Carpal Tunnel Release in Severe Carpal Tunnel Syndrome
This article describes the surgical technique of the opponensplasty using the PL tendon to the rerouted extensor pollicis brevis transfer. The procedure provides satisfactory outcomes for early functional recovery of the hand in patients with severe CTS.PMID:34034945 | DOI:10.1016/j.jhsa.2021.04.007 (Source: Hand Surgery)
Source: Hand Surgery - May 26, 2021 Category: Surgery Authors: Akihiro Hirakawa Shingo Komura Marie Nohara Tomihiro Masuda Yasuharu Matsushita Haruhiko Akiyama Source Type: research

Retinol binding protein 4 as a screening biomarker for hereditary TTR amyloidosis in African American adults with TTR V142I
The TTR V142I variant (previously known as V122I), associated with hereditary transthyretin amyloidosis (hATTR), is the most common TTR variant worldwide, with recent prevalence estimates of 1 in 330 individuals (1). Up to 4% of African American (AAs) in the U.S. are heterozygous for V142I (i.e., V142I+) (2), which, in part, is thought to explain the observation that cardiac amyloidosis (CA) is four times more common among AA than European descent patients over 60 years of age (3). .Non-cardiac clinical features of hATTR such as carpal tunnel syndrome, spinal stenosis and polyneuropathy ( “red flags”) can prece...
Source: Journal of Cardiac Failure - May 26, 2021 Category: Cardiology Authors: Amy R. Kontorovich, Noura S. Abul-Husn Source Type: research

Use of conservative therapy before and after surgery for carpal tunnel syndrome
Conservative therapies are typically offered to individuals who experience mild or intermittent symptoms of carpal tunnel syndrome (CTS) or postoperatively to subjects who have undergone carpal tunnel release.... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - May 26, 2021 Category: Orthopaedics Authors: Juhani Multanen, Mikko M. Uimonen, Jussi P. Repo, Arja H äkkinen and Jari Ylinen Tags: Research Source Type: research

Early Outcomes of Endoscopic Versus Open Carpal Tunnel Release
To compare the short-term outcomes of endoscopic carpal tunnel release (ECTR) and open carpal tunnel release (OCTR), including patient-reported outcomes, pain and satisfaction scores, return to work, and postoperative prescription pain medication use. (Source: The Journal of Hand Surgery)
Source: The Journal of Hand Surgery - May 25, 2021 Category: Surgery Authors: Megan R. Miles, Pragna N. Shetty, Kovid Bhayana, Imran S. Yousaf, Kavya K. Sanghavi, Aviram M. Giladi Tags: Editor ’s Choice Source Type: research

Do carpal Tunnel Hands Have Different Shape Compare to Normal Hands?
Arch Bone Jt Surg. 2021 Mar;9(2):180-188. doi: 10.22038/abjs.2020.41835.2131.ABSTRACTBACKGROUND: Given the fact that the carpal tunnel syndrome (CTS) happens as a consequence of the median nerve entrapment, besides other known factors, the shape and anthropometric characteristics of the carpal tunnel, wrist, and hand could be considered as a predisposing risk factor for idiopathic CTS. The aim of this study was to evaluate the morphology and radiologic scales in CTS hands.METHODS: In this prospective study, patients who underwent upper extremity electrodiagnostic studies were enrolled for hand morphologic and radiographic ...
Source: Hand Surgery - May 24, 2021 Category: Surgery Authors: Mohamad Sahebalam Golnaz Ghayyem Hassankhani Amin Azhari Ali Moradi Source Type: research

Do carpal Tunnel Hands Have Different Shape Compare to Normal Hands?
Arch Bone Jt Surg. 2021 Mar;9(2):180-188. doi: 10.22038/abjs.2020.41835.2131.ABSTRACTBACKGROUND: Given the fact that the carpal tunnel syndrome (CTS) happens as a consequence of the median nerve entrapment, besides other known factors, the shape and anthropometric characteristics of the carpal tunnel, wrist, and hand could be considered as a predisposing risk factor for idiopathic CTS. The aim of this study was to evaluate the morphology and radiologic scales in CTS hands.METHODS: In this prospective study, patients who underwent upper extremity electrodiagnostic studies were enrolled for hand morphologic and radiographic ...
Source: Hand Surgery - May 24, 2021 Category: Surgery Authors: Mohamad Sahebalam Golnaz Ghayyem Hassankhani Amin Azhari Ali Moradi Source Type: research

Preclinical diagnosis of wild-type transthyretin amyloid cardiomyopathy in a patient undergoing carpal tunnel release
Publication date: Available online 21 May 2021Source: Journal of Cardiology CasesAuthor(s): Naoya Nakashima, Seiji Takashio, Mami Morioka, Masato Nishi, Kyoko Hirakawa, Shinsuke Hanatani, Teruaki Masuda, Mitsuharu Ueda, Kenichi Tsujita (Source: Journal of Cardiology Cases)
Source: Journal of Cardiology Cases - May 22, 2021 Category: Cardiology Source Type: research

Opponensplasty by the Palmaris Longus Tendon to the Rerouted Extensor Pollicis Brevis Transfer With Endoscopic Carpal Tunnel Release in Severe Carpal Tunnel Syndrome
In patients with severe carpal tunnel syndrome (CTS), restoring thumb opposition is critical because this function is essential for proper pinching, grasping, and other complex hand movements. Opponensplasty is an effective procedure to preserve thumb function, with several methods reported. Camitz opponensplasty, using the palmaris longus (PL), is an option for patients with severe CTS. Recently, several modified Camitz procedures have been proposed to overcome the shortcomings of the original description. (Source: The Journal of Hand Surgery)
Source: The Journal of Hand Surgery - May 22, 2021 Category: Surgery Authors: Akihiro Hirakawa, Shingo Komura, Marie Nohara, Tomihiro Masuda, Yasuharu Matsushita, Haruhiko Akiyama Tags: Surgical Technique Source Type: research

Perioperative Laboratory Markers as Risk Factors for Surgical Site Infection After Elective Hand Surgery
J Hand Surg Am. 2021 May 17:S0363-5023(21)00203-3. doi: 10.1016/j.jhsa.2021.04.001. Online ahead of print.ABSTRACTPURPOSE: The purpose of this study was to test the null hypothesis that there is no association between perioperative laboratory markers (serum albumin and hemoglobin A1c [HbA1c]) and incidence of surgical site infection (SSI) after soft tissue upper extremity surgery.METHODS: We analyzed patient-level data from a large, insurance-based database containing supplemental laboratory results. We identified patients undergoing soft tissue upper extremity surgery (defined as carpal tunnel release, trigger finger rele...
Source: Hand Surgery - May 21, 2021 Category: Surgery Authors: Thompson Zhuang Lauren M Shapiro Nathaniel Fogel Marc J Richard Michael J Gardner Robin N Kamal Source Type: research

Perioperative Laboratory Markers as Risk Factors for Surgical Site Infection After Elective Hand Surgery
J Hand Surg Am. 2021 May 17:S0363-5023(21)00203-3. doi: 10.1016/j.jhsa.2021.04.001. Online ahead of print.ABSTRACTPURPOSE: The purpose of this study was to test the null hypothesis that there is no association between perioperative laboratory markers (serum albumin and hemoglobin A1c [HbA1c]) and incidence of surgical site infection (SSI) after soft tissue upper extremity surgery.METHODS: We analyzed patient-level data from a large, insurance-based database containing supplemental laboratory results. We identified patients undergoing soft tissue upper extremity surgery (defined as carpal tunnel release, trigger finger rele...
Source: Hand Surgery - May 21, 2021 Category: Surgery Authors: Thompson Zhuang Lauren M Shapiro Nathaniel Fogel Marc J Richard Michael J Gardner Robin N Kamal Source Type: research

Surgical treatment of carpal tunnel syndrome in advanced-stage upper extremity lymphedema: A case report
Rationale Despite significant advances in microsurgical techniques, simultaneous release of transverse carpal ligament (TCL) and lymphovenous anastomosis (LVA) surgeries may be effective for treatment of carpal tunnel syndrome (CTS) and advanced-stage lymphedema. This case report describes the successful treatment of lymphedema with LVA in a patient with CTS and advanced-stage lymphedema. Patient concerns A 60-year-old female patient was referred to our lymphedema clinic with a 12-year history of chronic, acquired, right upper extremity lymphedema and CTS following right mastectomy and axillary lymph node dissec...
Source: Medicine - May 21, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Manual medicine, manual treatment : Principles, mode of action, indications and evidence
Unfallchirurg. 2021 May 19. doi: 10.1007/s00113-021-01004-8. Online ahead of print.ABSTRACTManual medicine is the medical discipline that comprehensively deals with the diagnosis, treatment and prevention of reversible functional disorders of the musculoskeletal system and other related organ systems. The article illustrates the neuroanatomical and neurophysiological basic elements and mechanisms of manual medical diagnostics and treatment. Based on the most recent literature and in consideration of various scientific guidelines, the evidence-based effectiveness of manual medical procedures is presented. In detail: acute a...
Source: Der Unfallchirurg - May 19, 2021 Category: Orthopaedics Authors: Hermann Locher Source Type: research