Fungi cause brain infection and impair memory in mice
(Baylor College of Medicine) Researchers report that the fungus Candida albicans can cross the blood-brain barrier and trigger an inflammatory response that results in the formation of granuloma-type structures and temporary mild memory impairments in mice. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 4, 2019 Category: Infectious Diseases Source Type: news

FDA Wants to Change the De Novo Pathway
Last week, FDA revealed plans to modernize the 510(k) clearance pathway, which was adopted in 1976 and now accounts for the majority of medical devices the agency reviews. This week, the agency has turned its attention to the de novo pathway for medical devices. The de novo pathway is used for the review of novel, low to moderate risk devices for which general controls, or general and special controls, provide a reasonable assurance of safety and effectiveness, but for which there is no existing predicate to use to determine substantial equivalence. According to FDA Commissioner Scott Go...
Source: MDDI - December 4, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Business Source Type: news

Medical News Today: Is there a link between psoriasis and < em > Candida < /em > ?
While researchers know there is a link between Candida, a type of yeast, and psoriasis, they do not fully understand how the two are related. Learn more with this article. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2018 Category: Consumer Health News Tags: Psoriasis Source Type: news

BioGX Launches 5 new CE Mark IVD Tests, Expands Sexual Health Panels on the BD MAX(TM)
AMSTERDAM, Oct. 23, 2018 -- (Healthcare Sales & Marketing Network) -- BioGX B.V., recently released five (5) new sexual health CE Mark IVD products on the BD MAXTM automated sample-to-result platform, making the BD MAXTM one of the most comprehensive sexu... Diagnostics, Regulatory, Product Launch BioGX, Candida, HSV, HSVHD (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 23, 2018 Category: Pharmaceuticals Source Type: news

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment
Host injury triggers feedback mechanisms that limit tissue damage. Conventional type 1 dendritic cells (cDC1s) express dendritic cell natural killer lectin group receptor-1 (DNGR-1), encoded by the gene Clec9a, which senses tissue damage and favors cross-presentation of dead-cell material to CD8+ T cells. Here we find that DNGR-1 additionally reduces host-damaging inflammatory responses induced by sterile and infectious tissue injury in mice. DNGR-1 deficiency leads to exacerbated caerulein-induced necrotizing pancreatitis and increased pathology during systemic Candida albicans infection without affecting fungal burden. T...
Source: ScienceNOW - October 18, 2018 Category: Science Authors: del Fresno, C., Saz-Leal, P., Enamorado, M., Wculek, S. K., Martinez-Cano, S., Blanco-Menendez, N., Schulz, O., Schulz, O., Gallizioli, M., Miro-Mur, F., Cano, E., Planas, A., Sancho, D. Tags: Immunology reports Source Type: news

Arid5a makes the IL-17A/F-responsive pathway less arid
The cytokine interleukin-17A/F (IL-17A/F) not only protects the skin and mucosae against Candida albicans infection in mice and humans but also promotes autoimmunity and autoinflammation in mice. In this issue of Science Signaling, Amatya et al. report that the RNA binding protein Arid5a promotes responses to IL-17A/F through multiple mechanisms. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - October 9, 2018 Category: Science Authors: Puel, A., Casanova, J.-L. Tags: STKE Focus Source Type: news

Medical News Today: What to know about esophageal thrush
Esophageal thrush is a fungal infection of the food pipe. It occurs when a naturally occurring fungus called Candida grows out of control. Esophageal thrush is a serious condition, causing pain and difficulty swallowing. It may also spread to other parts of the body. Learn more about esophageal thrush here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 8, 2018 Category: Consumer Health News Tags: Ear, Nose and Throat Source Type: news

C auris Outbreak Tied to Skin Surface Temperature Probe C auris Outbreak Tied to Skin Surface Temperature Probe
Environmental transmission of multidrug-resistant Candida auris infection in a neurosciences intensive care unit in Britain was traced to reusable skin surface axillary temperature probes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 4, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Hospital's Fungal Outbreak Blamed on Reusable Thermometers
(MedPage Today) -- Candida auris superbugs found on skin-surface axillary probes (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 3, 2018 Category: Infectious Diseases Source Type: news

Large Cluster of Fluconazole-Resistant Candida auris Found Large Cluster of Fluconazole-Resistant Candida auris Found
Candida auris infections resistant to fluconazole (and sometimes to amphotericin) were identified in 20 hospitals and nursing homes, according to the CDC.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 17, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

32 Children ’s Medicines Recalled For Potential ‘ Microbial Contamination ’
(CBS Local) – King Bio is voluntarily recalling 32 children’s medicines because of potential “microbial contamination,” the company said in a statement on Wednesday. The medicines, which include those meant to relieve common illnesses including fever, cough, flu, tummy aches, nosebleeds, and earaches, were sold nationwide. According to the company, “the use of drugs products with microbial contamination could potentially result in increased infections that may require medical intervention, and could result in infections that could be life threatening to certain individuals.” No injurie...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 23, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News children's medication FDA Local TV Recall talkers Source Type: news

Recall: King Bio Kids Products For Contamination
It is the second time in as many months that the company has issued a recall over potential contamination. In July, it recalled four lots of teething liquids, lymph detox, and candida products after an FDA inspection found them to be contaminated with bacteria. (Source: WebMD Health)
Source: WebMD Health - August 23, 2018 Category: Consumer Health News Source Type: news

Medical News Today: About Candida albicans: Natural yeast and problematic infections
Candida albicans is the most common yeast that we live with. It ’s found naturally on our skin and in certain parts of our bodies. We explain what Candida albicans is and 11 scenarios when its overgrowth or presence means infection. Learn about other Candida infections and how they’re diagnosed, too. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 9, 2018 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Candida auris and non-albicans biofilms
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 23, 2018 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

King Bio Issues Voluntary Nationwide Recall of Aquaflora Candida HP9, Lymph Detox, and Baby Teething Liquids Due to Microbial Contamination
King Bio is voluntarily recalling four lots of Aquaflora Candida HP9, Lymph Detox, and Baby Teething liquids to the consumer level. During a routine inspection by the U.S. Food and Drug Administration, the products were found to contain microbial contaminants Pseudomonas Brenneri, Pseudomonas Fluroescens and Burkholderia Multivorans. (Source: Food and Drug Administration)
Source: Food and Drug Administration - July 20, 2018 Category: Food Science Source Type: news