PPP2CA Inhibition Promotes Ferroptosis Sensitivity Through AMPK/SCD1 Pathway in Colorectal Cancer
ConclusionUltimately, we conclude that PPP2CA may regulate Erastin-induced ferroptosis through AMPK/SCD1 signaling pathway. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 18, 2024 Category: Gastroenterology Source Type: research
Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion
ConclusionOur review provides evidence for the impact of AHR ligands on adrenocortical function and indicates further avenues of research to better clarify its effects. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 18, 2024 Category: Endocrinology Source Type: research
Advancements in fertility preservation strategies for pediatric male cancer patients: a review of cryopreservation and transplantation of immature testicular tissue
Recently, there has been increasing emphasis on the gonadotoxic effects of cancer therapy in prepubertal boys. As advances in oncology treatments continue to enhance survival rates for prepubertal boys, the ne... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - April 18, 2024 Category: Endocrinology Authors: Zih-Yi Sung, Yong-Qi Liao, Jung-Hsiu Hou, Hong-Hsien Lai, Sung-Ming Weng, Hai-Wei Jao, Buo-Jia Lu and Chi-Huang Chen Tags: Review Source Type: research
Effect of radiotherapy on the surface roughness and microhardness of contemporary bioactive restorative materials
ConclusionThe effect of radiotherapy might differ according to the type of the restorative material. Although results may differ for other tested materials, giomer tends to exhibit worse behaviour in terms of both surface roughness and microhardness.Clinical relevanceIn patients undergoing head and neck radiotherapy, it should be taken into consideration that the treatment process may also have negative effects on the surface properties of anti-caries restorative materials. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research
Effects of dependent care theory-based post-surgical home care intervention on self-care, symptoms, and caregiver burden in patients with primary brain tumor and their caregivers: a randomized controlled trial
ConclusionDependent care theory-based post-surgical home care intervention increased patients ’ self-care and reduced symptoms and their effects. It also reduced the caregiver burden. Dependent care theory can guide the nursing practices of nurses who provide institutional and/or home care services to patients with chronic diseases and their caregivers.Trial RegistrationNCT05328739 on April 14, 2022 (retrospectively registered). (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research
