Intravital calcium imaging in myeloid leukocytes identifies calcium frequency spectra as indicators of functional states
Decoding intracellular calcium signals in immune cells in live mice reveals their functional status during inflammation. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - July 26, 2022 Category: Science Source Type: news
Carbide gun-related ocular injuries: a case series - Arora A, Priyadarshini SR, Das S, Mohanty A, Shanbhag SS, Sahu SK.
PURPOSE: The purpose of this study was to report a case series of sight-threatening ocular injuries caused by calcium carbide guns used as fire crackers. METHODS: Medical records of 15 eyes of 14 patients with ocular injuries caused while using car... (Source: SafetyLit)
Source: SafetyLit - July 25, 2022 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
Janssen Receives Positive CHMP Opinion for Novel Bispecific Antibody TECVAYLI ® (teclistamab) for the Treatment of Patients with Relapsed and Refractory Multiple Myeloma (RRMM)
BEERSE, Belgium, 22 July 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended conditional marketing authorisation (CMA) for TECVAYLI® (teclistamab) as monotherapy for adult patients with relapsed and refractory multiple myeloma (RRMM), who have received at least three prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 antibody and have demonstrated disease progression on the last therapy. Teclistamab is an off-the-shelf, T-cell r...
Source: Johnson and Johnson - July 22, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news
Effects of Milk Intake on Calcium Homeostasis and CV Outcome Effects of Milk Intake on Calcium Homeostasis and CV Outcome
What is the acute impact of calcium intake from milk products on measures of cardiovascular health?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 14, 2022 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Detecting Coronary Calcium in Young Adults: Are We There Yet? Detecting Coronary Calcium in Young Adults: Are We There Yet?
Should young adults aged 30-45 years be considered for assessment of coronary artery calcium, and if so, who?Journal of the American College of Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2022 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Comparative Evaluation of Ozonoid Olive Oil and Calcium Hydroxide as an Indirect Pulp Capping Agent in Primary Mandibular Second Molar: A Randomized Controlled Trial
Conclusion: The results of this study showed that the success of IPC is independent of capping material. Ozonoid olive oil, an antimicrobial agent, can also be used for IPC. The success of the IPC procedure depends on a reduction in the bacterial count and sealing of the tooth with hermetic restoration. More clinical studies with a larger sample size and longer follow-up duration are required for understanding the efficacy of this material.Clinical significance: Ozonoid olive oil can be used as an IPC agent in primary molars and also for a bacterial reduction in dentinal caries. (Source: Dental Technology Blog)
Source: Dental Technology Blog - July 1, 2022 Category: Dentistry Source Type: news
How Changing Your Diet Could Have a Major Impact on Managing Lupus Symptoms
After Jewell Singletary was diagnosed with lupus, she developed rheumatoid arthritis as well—a common pairing, since both are autoimmune conditions—and had to use a cane to navigate her college campus. When she graduated, the now 38-year-old New Jersey resident decided to be more focused on supporting her health, in an effort to maintain her mobility as she began her career.
She started in the kitchen.
First to be tossed were sugary drinks, fried foods, and highly processed options, she says. Once she eliminated them, it didn’t take long before she could discard one more important item: her cane.
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Source: TIME: Health - June 29, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Diet & Nutrition freelance healthscienceclimate Source Type: news
Janssen Announces U.S. FDA Breakthrough Therapy Designation Granted for Talquetamab for the Treatment of Relapsed or Refractory Multiple Myeloma
June 29, 2022 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for talquetamab for the treatment of adult patients with relapsed or refractory multiple myeloma, who have previously received at least 4 prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 antibody. Talquetamab is an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting both GPRC5D, a novel drug target, on multiple myeloma cells and CD3 o...
Source: Johnson and Johnson - June 29, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Rosuvastatin Calcium Tablets (rosuvastatin calcium) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 29, 2022 Category: Drugs & Pharmacology Source Type: news
Novel Drug for Relapsing-Remitting MS: New Phase 2 Data Novel Drug for Relapsing-Remitting MS: New Phase 2 Data
The second-generation selective DHODH inhibitor vidofludimus calcium met a phase 2 trial primary endpoint of suppressing new active lesions on MRI and was well tolerated.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 22, 2022 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Clinical and radiographic features of facial cosmetic materials: A systematic review
Conclusion: Conventional radiography, cone-beam computed tomography, and multi-detector computed tomography are useful to differentiate several cosmetic materials. Their magnetic resonance imaging appearance was highly variable. The infrequent inclusion of cosmetic materials in the differential diagnosis implies that medical and dental specialists may be unfamiliar with the radiographic appearance of these materials in the face. (Source: Dental Technology Blog)
Source: Dental Technology Blog - June 22, 2022 Category: Dentistry Source Type: news
Higher Dairy Intake May Up Risk for Prostate Cancer
However, association does not hold for nondairy calcium intake (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 16, 2022 Category: Cancer & Oncology Tags: Internal Medicine, Oncology, Urology, Journal, Source Type: news
Higher Dairy Intake May Up Risk for Prostate Cancer
THURSDAY, June 16, 2022 -- Men with higher intake of dairy foods, but not nondairy calcium, may have a higher risk for prostate cancer versus men with lower intakes, according to a study published June 8 in the American Journal of Clinical... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 16, 2022 Category: Pharmaceuticals Source Type: news
Voltage-gated Ca2+ channel proteins do not function as ion channels in T cells
A study finds a nonchannel function for a voltage-gated calcium channel β-subunit in T lymphocytes. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - June 14, 2022 Category: Science Source Type: news
Janssen Presents Updated Data at EHA for Teclistamab in Patients with Relapsed or Refractory Multiple Myeloma
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced updated efficacy and safety results from the teclistamab cohort of the Phase 1b TriMM-2 study (NCT04108195). Teclistamab, an investigational, off-the-shelf, T-cell redirecting bispecific antibody targeting B-cell maturation antigen (BCMA) is being studied in combination with DARZALEX FASPRO® (daratumumab and hyaluronidase-fihj) in patients with relapsed or refractory multiple myeloma (RRMM) who have received three or more prior lines of therapy.1 Patients in the study, including a high proportion with prior anti-CD38 exposur...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
