Quantal leaps in understanding Ca2+ signaling: A “Taylored” approach | Science Signaling
The organizers of a symposium honoring the contributions of Colin Taylor to calcium signaling research summarize the presentations. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - November 29, 2022 Category: Science Source Type: news
MRIs of Covid patients show clusters of plaques in areas responsible for tiredness, anxiety
The study, done by researchers in India, found deposits of blood, calcium and iron at abnormal levels in key regions of the brain. The study was done using MRI scans six months after an infection. (Source: the Mail online | Health)
Source: the Mail online | Health - November 21, 2022 Category: Consumer Health News Source Type: news
How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke.
“Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news
'Groundbreaking' Results With Nasal Spray for Home Tachycardia Conversion
(MedPage Today) -- CHICAGO -- The investigational L-type calcium channel blocker etripamil, formulated as a self-administered nasal spray, shortened spontaneous paroxysmal supraventricular tachycardia episodes among patients in at-home settings... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 9, 2022 Category: Cardiology Source Type: news
Late-Breaking Data from Pivotal Phase 3 PRECISION Study Demonstrates Significant and Sustained Effect of Aprocitentan on Lowering Blood Pressure for Patients with Difficult-to-Control Hypertension
RARITAN, NJ, November 7, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson, in collaboration with Idorsia Ltd, today announced results from the Phase 3 PRECISION study, which found aprocitentan, an investigational, novel dual endothelin receptor antagonist (ERA), significantly reduced blood pressure (BP) and maintained the effect for up to 48 weeks when added to standardized combination background antihypertensive therapy in patients with difficult-to-control hypertension (sometimes referred to as resistant hypertension). These data were presented as a Late-Breaking Science presentation during the Amer...
Source: Johnson and Johnson - November 7, 2022 Category: Pharmaceuticals Source Type: news
What to Know About Bariatric Surgery for Type 2 Diabetes
The term bariatric is derived from the Greek words for “weight” and “to treat.” Originally, as its name denotes, this form of surgery was aimed at helping people manage obesity. But as medical science’s understanding of bariatric surgery improved, experts recognized that these procedures could also help people with obesity-related health conditions, including Type 2 diabetes.
“In 1999 when I was a junior resident in general surgery, I was struck by the observation that patients who had this type of surgery were very rapidly seeing improvement in their diabetes,” says Dr. Francesco ...
Source: TIME: Health - November 3, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease healthscienceclimate Source Type: news
Preliminary evaluation of a novel point of care diagnostic device for sports-related concussion - Wu Y, Abner EL, Conley C, Smoot MK, Hosey R, Kaiser K, Lovell MA.
OBJECTIVE: Visinin-like protein 1 (VILIP-1) is a neuron-specific calcium sensor protein rapidly released into blood after mild traumatic brain injury (mTBI) and may be a suitable biomarker for identification of sports-related concussion (SRC). The objectiv... (Source: SafetyLit)
Source: SafetyLit - November 2, 2022 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news
It may be possible to cram more neutrons into atomic nuclei than previously thought
A new form of sodium—the element that combines with chlorine to make salt—packs a whacking 28 neutrons in its atomic nucleus, along with the 11 protons that define its chemical identity. With more than double the 13 neutrons in natural sodium, the neutron-rich isotope of the element is so extreme that few theoretical models predicted its existence. “It’s a surprise that these neutrons keep on hanging on,” says Katherine Grzywacz-Jones, a nuclear physicist at the University of Tennessee, Knoxville, who was not involved in the work.
Researchers at Japan’s RIKEN Nishina Center for Accelerator-Based Science c...
Source: ScienceNOW - October 26, 2022 Category: Science Source Type: news
U.S. FDA Approves TECVAYLI ™ (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma
HORSHAM, Pa., October 25, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) approved TECVAYLI™ (teclistamab-cqyv) for the treatment of adult patients with relapsed or refractory multiple myeloma, who previously received four or more prior lines of therapy, including a proteasome inhibitor, immunomodulatory drug and anti-CD38 monoclonal antibody.1 TECVAYLI™ is a first-in-class, bispecific T-cell engager antibody that is administered as a subcutaneous treatment.1 This off-the-shelf (or ready to use) therapy uses innovative science to ac...
Source: Johnson and Johnson - October 25, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Overdoing zinc can cause copper deficiency warns expert - impacts energy and immunity
Taking too much zinc on a daily basis can have a negative effect on your body's copper and calcium levels, potentially causing more health problems down the line, an expert has warned. (Source: Daily Express - Health)
Source: Daily Express - Health - October 23, 2022 Category: Consumer Health News Source Type: news
Soil ’s Power as a Climate Solution Has Often Been Overlooked. Until Now
This article is part of a series on key topics in the climate crisis for time.com and CO2.com, a division of TIME that helps companies reduce their impact on the planet. For more information, go to co2.com (Source: TIME: Science)
Source: TIME: Science - October 21, 2022 Category: Science Authors: Jennifer Fergesen Tags: Uncategorized climate change Explainer Food & Agriculture healthscienceclimate Source Type: news
Milestone Pharmaceuticals Announces Positive Results from Phase 3 RAPID Clinical Trial of Etripamil Nasal Spray in Patients with Paroxysmal Supraventricular Tachycardia
Trial met its primary endpoint, with 64.3% of patients self-administering etripamil converting to sinus rhythm within 30 minutes compared to 31.2% on placebo (HR = 2.62, p... Biopharmaceuticals, Cardiology Milestone Pharmaceuticals, etripamil, calcium channel blocker, PSVT (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 17, 2022 Category: Pharmaceuticals Source Type: news
Statins: Polyuria may signal a potentially 'fatal' calcium leak into the bloodstream
The drug has been hailed as a game-changer in the war on heart disease, but sometimes it has unnatural effects. (Source: Daily Express - Health)
Source: Daily Express - Health - October 13, 2022 Category: Consumer Health News Source Type: news
AI Model Quantifies Coronary Artery Calcium From PET CTAC Scans
WEDNESDAY, Oct. 5, 2022 -- Deep-learning (DL) positron emission tomography (PET) computed tomography (CT) attenuation correction (CTAC) scan scores may predict cardiovascular risk similarly to standard coronary artery calcium (CAC) scores, according... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 5, 2022 Category: Pharmaceuticals Source Type: news
Fractures & Intellectual Disability; Incorporating Telehealth; Start Calcium Young?
(MedPage Today) -- Incidence of fractures -- and particularly hip fractures -- was far higher in people with intellectual disabilities, indicating early-onset osteoporosis. (eClinicalMedicine)
Between 2009-2010 and 2014-2015, life expectancy... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - October 5, 2022 Category: Endocrinology Source Type: news
