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18 Diseases The World Has Turned Its Back On
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. More than 1 billion people on the planet suffer from illnesses that the world pays little attention to. Neglected tropical diseases are a group of at least 18 diseases that primarily affect people living in poverty in tropical regions of the world and are virtually unknown elsewhere, according to the World Health Organization. These are diseases like river blindness, which has infected 18 million people worldwide and caused blindness in 270,000 people; or...
Source: Healthy Living - The Huffington Post - December 6, 2016 Category: Consumer Health News Source Type: news

18 Diseases The World Has Turned Its Back On
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. More than 1 billion people on the planet suffer from illnesses that the world pays little attention to. Neglected tropical diseases are a group of at least 18 diseases that primarily affect people living in poverty in tropical regions of the world and are virtually unknown elsewhere, according to the World Health Organization. These are diseases like river blindness, which has infected 18 million people worldwide and caused blindness in 270,000 people; or...
Source: Science - The Huffington Post - December 6, 2016 Category: Science Source Type: news

Africa: Buruli Ulcer - Africa's Neglected but Third Most Common Bacterial Disease
[The Conversation Africa] Buruli ulcer is a skin infection that kills the cells and tissue in an affected area and creates ulcers on the skin. It is caused by a bacteria and is the third most common bacterial disease after TB and leprosy. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - April 20, 2016 Category: African Health Source Type: news

Cure for flesh-eating skin disease one step closer
Scientists have made an important breakthrough in the fight against the flesh-eating tropical skin disease Buruli ulcer, by their discovery that the bacteria causes a blood clot in patients' skin, similar to those that cause deep vein thrombosis (DVT). The new findings mean that, like DVT, the clots may respond to anticoagulant medicines, heal more quickly and with fewer side effects than with antibiotics alone. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 16, 2015 Category: Science Source Type: news

Breakthrough finding brings cure for flesh-eating skin disease 1 step closer
(University of Surrey) Scientists from the University of Surrey have made an important breakthrough in the fight against the flesh-eating tropical skin disease Buruli ulcer, by their discovery that the bacteria causes a blood clot in patients' skin, similar to those that cause deep vein thrombosis (DVT). The new findings mean that, like DVT, the clots may respond to anticoagulant medicines, heal more quickly and with fewer side effects than with antibiotics alone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 16, 2015 Category: Infectious Diseases Source Type: news

Liberia: Deny Buruli Ulcer the Spotlight
[Observer]Bong County, still reeling from the grievous impact of the Ebola virus that claimed over a hundred lives, is now confronted with an outbreak of Buruli Ulcer which is trying to edge its way into center stage. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - October 24, 2014 Category: African Health Source Type: news

Can injuries to the skin be painless?
(INSERM (Institut national de la santé et de la recherche médicale)) Inserm researchers and their collaborators have studied lesions in patients with Buruli ulcer, a tropical disease. They show that, despite the extent and severity of these wounds, they are less painful than others that seem relatively minor (e.g. scratches, low-degree burns). They discovered an analgesic mechanism that limits the transmission of pain signals to the brain that may be useful in developing new drugs for pain relief. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 19, 2014 Category: Infectious Diseases Source Type: news

According to the WHO, Neglected Tropical Diseases (NTDs) affect over 1 billion people worldwide, and are devastating to patients in the developing world. What is being done to get treatments to these patients and to speed development of new treatments?
conversationsneglected tropical diseasestropical diseasesnew medicinesInnovationOpinion46864687468846894690469246914693Neglected Tropical Diseases (NTDs) impact more than a billion people in some of the poorest, most remote parts of the world, blinding, disabling, disfiguring and sickening those infected. They have a negative impact on life expectancy, productivity and childhood education -- all of which create a cycle of poverty and stigma for affected communities. Today, because of renewed and new commitments, millions impacted by NTDs are being treated, several NTDs are being controlled effectively, and some even elimin...
Source: PHRMA - December 10, 2013 Category: Pharmaceuticals Authors: Stephen Source Type: news

Cytoskeletal Dysregulation Underlies Buruli Ulcer Formation
Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers. In this issue of the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institue in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP. They found that excessive N-WASP activity caused defects in cell adhesion and migration that impaired the integrity of the skin... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 18, 2013 Category: Consumer Health News Tags: Dermatology Source Type: news

JCI early table of contents for Mar. 15, 2013
(Journal of Clinical Investigation) The following release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Mar. 15, 2013, in the JCI: Cytoskeletal dysregulation underlies Buruli ulcer formation; Sorting out fertility after childhood cancer; and many more. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 15, 2013 Category: Global & Universal Source Type: news

Cytoskeletal dysregulation underlies Buruli ulcer formation
(Journal of Clinical Investigation) In this issue of the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institute in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 15, 2013 Category: Global & Universal Source Type: news

Nigeria: 'Country Still Leprosy Endemic'
[Daily Trust]Despite achieving elimination targets, Nigeria still detects and records news cases of leprosy, coordinator of the National Tuberculosis, Leprosy and Buruli Ulcer Control Programme, Dr Joshua Obasanya, has said. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 30, 2013 Category: African Health Source Type: news