Why People Still Choose PEG Tube at End of Life-Do Religion, Culture, Race, or Ethnicity Play a Role?
1. Participants will be able to design their own comprehensive, culturally sensitive, educational PCC initiative to support patients and families “choosing wisely” to support and advise patients with advanced illness and families considering PEG placement.2. Participants will be able to offer some statistical support in terms of religion, race, ethnicity, and culture to help dissuade patients and families from choosing PEG tube placement when there's no perceived benefit. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Isabella Park, Sudheer Akella, Guisela Hernandez, Hussein Abu-Hashish, Michele Johnson, Elisabeth Loccisano, Fredrick Lambert, Jessica Chappina, Christian Nouryan, Catherine Cho, Asha Gajraj, Edith Burns Source Type: research

Embers in Existence: Spiritual and Existential Distress in a Burn Injury Resulting from Spiritual Practice
1. Participants will better understand the distinct spiritual and existential challenges faced by pediatric burn patients, especially those stemming from fire-related religious practices.2. Participants will be able to identify how interdisciplinary collaboration between pediatric palliative care, spiritual care, and burn surgery specialists can effectively identify and address key themes like meaning-making and identity in pediatric burn cases. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Jennifer A. Salant, Stephen B. Douglas, Claire Slusarz, Philip Chang, CB Stewart Source Type: research

Handle with Care: Transformative Learning as Pedagogy in an Under-Resourced Health Care Context
Teach Learn Med. 2024 Apr 18:1-10. doi: 10.1080/10401334.2024.2332885. Online ahead of print.ABSTRACTIssue: A significant component of health professions education is focussed on students' exposure to the social determinants of health and the challenges that patients within the health care system face. An appropriate way to provide such exposure is through distributed clinical training. This usually entails students training in smaller groups along the continuum of care, away from tertiary academic hospitals. This also means students are away from their existing academic and social support systems. It is evident that knowl...
Source: Teaching and Learning in Medicine - April 18, 2024 Category: Universities & Medical Training Authors: Jana M üller Rhoda Meyer Jason Bantjes Elize Archer Ian Couper Source Type: research

Handle with Care: Transformative Learning as Pedagogy in an Under-Resourced Health Care Context
Teach Learn Med. 2024 Apr 18:1-10. doi: 10.1080/10401334.2024.2332885. Online ahead of print.ABSTRACTIssue: A significant component of health professions education is focussed on students' exposure to the social determinants of health and the challenges that patients within the health care system face. An appropriate way to provide such exposure is through distributed clinical training. This usually entails students training in smaller groups along the continuum of care, away from tertiary academic hospitals. This also means students are away from their existing academic and social support systems. It is evident that knowl...
Source: Rural Remote Health - April 18, 2024 Category: Rural Health Authors: Jana M üller Rhoda Meyer Jason Bantjes Elize Archer Ian Couper Source Type: research

SubSol-HIe is an AMPK-dependent hypoxia-responsive subnucleus of the nucleus tractus solitarius that coordinates the hypoxic ventilatory response and protects against apnoea in mice
Pflugers Arch. 2024 Apr 18. doi: 10.1007/s00424-024-02957-6. Online ahead of print.ABSTRACTFunctional magnetic resonance imaging (fMRI) suggests that the hypoxic ventilatory response is facilitated by the AMP-activated protein kinase (AMPK), not at the carotid bodies, but within a subnucleus (Bregma -7.5 to -7.1 mm) of the nucleus tractus solitarius that exhibits right-sided bilateral asymmetry. Here, we map this subnucleus using cFos expression as a surrogate for neuronal activation and mice in which the genes encoding the AMPK-α1 (Prkaa1) and AMPK-α2 (Prkaa2) catalytic subunits were deleted in catecholaminergic cells b...
Source: Pflugers Archiv : European Journal of Physiology - April 18, 2024 Category: Physiology Authors: Sandy MacMillan David P Burns Ken D O'Halloran A Mark Evans Source Type: research

Role of reactive carbonyls and superoxide radicals in protein damage by cigarette smoke extracts: Comparison of Heat-Not-Burn e-cigarettes to conventional cigarettes
This study investigated the relative importance of these pathways during exposure of a model protein to fresh cigarette emission extracts. Briefly, protein carbonyl adducts were estimated in bovine serum albumin following incubation in buffered solutions with whole cigarette emissions extracts prepared from either a single 1R6F research cigarette or a single "Heat-not-Burn" e-cigarette. Although both extracts caused concentration-dependent protein carbonylation, conventional cigarette extracts produced higher adduct yields than e-cigarette extracts. Superoxide radical generation by conventional and e-cigarette emissions wa...
Source: Chemico-Biological Interactions - April 18, 2024 Category: Molecular Biology Authors: Nicholas Merritt Cameron Urquhart Philip Burcham Source Type: research

Burnt remains of Maya royalty mark a dramatic power shift
Nature, Published online: 18 April 2024; doi:10.1038/d41586-024-01075-8Finds in pyramid at Guatemalan site suggest that remains were disinterred and desecrated in a public ritual. (Source: Nature AOP)
Source: Nature AOP - April 18, 2024 Category: Research Source Type: research

The potential of pumice as a litter material and its influence on growth performance, carcass parameters, litter quality traits, behavior, and welfare in broiler chickens
This study evaluated the possibilities of pumice (light stones) as litter material in broiler production. Experimental treatments included wood shavings (WS), acidic pumice (AP), and basic pumice (BP) alone, and in combination; wood shaving  + acidic pumice (WSAP) and wood shaving + basic pumice (WSBP) in a ratio of 1:1. Two trials were performed, one in summer, and the other in winter. Each trial involved 750 mixed-sex Ross (308) broilers. Also, there were 15 replicate pens with 50 broilers and a stocking density of 12.5 birds /m2 for each pen at the beginning of each trial. Performance, litter quality, carcass pa...
Source: Tropical Animal Health and Production - April 18, 2024 Category: Veterinary Research Source Type: research

Charred bones are signs of Maya ritual to erase past rulers
In 2022, Christina Halperin was excavating a pile of rubble in a Maya pyramid at a Guatemalan site called Ucanal. As she sorted through thousands of shattered greenstones, seashells, and obsidian pieces, she noticed something peculiar. “This soil was so sooty and full of carbon,” the University of Montreal archaeologist recalls. “You couldn’t excavate … you couldn’t be clean.” Now, her team knows what the dense, sooty debris was made of: the burnt bones of ancient Maya royalty and their ornaments. In a paper published today in Antiquity , the researchers describe the unusual burning event...
Source: Science of Aging Knowledge Environment - April 17, 2024 Category: Geriatrics Source Type: research

A prospective analysis of the efficacy of phase II autologous skin grafting on deep second ‑degree burns on the dorsum of the hand
Exp Ther Med. 2024 Mar 27;27(5):238. doi: 10.3892/etm.2024.12526. eCollection 2024 May.ABSTRACTThe aim of the present study was to investigate the possibility of reducing the damage to the donor site while preserving the functional recovery of the dorsum of the hand following burn injury. An attempt was made to analyze the effect of a phased surgery approach on inflammatory indicators. A two-phase treatment was administered on a total of 64 patients with deep second-degree burns on the dorsum of the hand who were admitted to Guangzhou Red Cross Hospital between January 2020 and March 2023. During phase I treatment, the wou...
Source: Experimental and Therapeutic Medicine - April 17, 2024 Category: General Medicine Authors: Jing'en Sun Siman Su Songsong Jiao Gang Li Zhi Zhang Weihua Lin Shuyao Zhang Source Type: research

30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Reproductive Biology)
Source: Reproductive Biology - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research

30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Biology of Reproduction)
Source: Biology of Reproduction - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research

A prospective analysis of the efficacy of phase II autologous skin grafting on deep second ‑degree burns on the dorsum of the hand
Exp Ther Med. 2024 Mar 27;27(5):238. doi: 10.3892/etm.2024.12526. eCollection 2024 May.ABSTRACTThe aim of the present study was to investigate the possibility of reducing the damage to the donor site while preserving the functional recovery of the dorsum of the hand following burn injury. An attempt was made to analyze the effect of a phased surgery approach on inflammatory indicators. A two-phase treatment was administered on a total of 64 patients with deep second-degree burns on the dorsum of the hand who were admitted to Guangzhou Red Cross Hospital between January 2020 and March 2023. During phase I treatment, the wou...
Source: Experimental and Therapeutic Medicine - April 17, 2024 Category: General Medicine Authors: Jing'en Sun Siman Su Songsong Jiao Gang Li Zhi Zhang Weihua Lin Shuyao Zhang Source Type: research

30 years of (re)productive biology a symposium honoring professor Martin M. Matzuk, MD, PhD
Biol Reprod. 2024 Apr 17:ioae051. doi: 10.1093/biolre/ioae051. Online ahead of print.NO ABSTRACTPMID:38629590 | DOI:10.1093/biolre/ioae051 (Source: Reproductive Biology)
Source: Reproductive Biology - April 17, 2024 Category: Reproduction Medicine Authors: T Rajendra Kumar Kathleen H Burns Wei Yan Source Type: research

Medico-legal evaluation of burn trauma injuries. Epidemiological features and predictors of mortality and other adverse outcomes
Sagah G.A. et al recently reported the results of a prospective study addressing the adverse outcomes of acute burn trauma and the implications for an integrated medico-legal evaluation in the realm of severe thermal injury [1]. Despite annual estimates of about 11 million burn injuries worldwide that can be associated with substantial morbidity and mortality, burns are yet considered an underappreciated form of trauma [2,3]. Recent advances in treatment and prevention of burns however show promise, with declining burn incidence and severity of the injury, mostly in highly developed countries [4]. (Source: Injury)
Source: Injury - April 17, 2024 Category: Orthopaedics Authors: Daphne J. Theodorou, Stavroula J. Theodorou, Ioannis D. Gelalis Tags: Letter to the Editor Source Type: research