Clinical Center Grand Rounds: Exploring the link between Sickle Cell, α -Thalassemia, P Falciparum Malaria and Burkitt Lymphoma in Africa
Sam Mbulaiteye, MBChB, M.Phil., M.Med. Senior Investigator Infections and Immunoepidemiology Branch Division of Cancer Epidemiology and Genetics (DCEG) National Cancer Institute, NCI and Swee Lay Thein, B.S., F.R.C.P., F.R.C.Path., D.Sc., FMedSci Chief, Laboratory of Sickle Cell Genetics and Pathophysiology Chief, Sickle Cell Branch National Heart, Lung, and Blood Institute, NHLBIFor more information go tohttps://clinicalcenter.nih.gov/about/news/grcurrent.htmlAir date: 5/10/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - May 8, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Burkitt lymphoma: a model of polymicrobial carcinogenesis and global oncology
Presented by: Sam M. Mbulaiteye, MBChB, MPhil, MMed., Senior Investigator, NCI DCEG, NIHCategory: NIH Director's SeminarsAired date: 03/06/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - March 10, 2015 Category: Journals (General) Tags: Past Events Source Type: video
Burkitt lymphoma: a model of polymicrobial carcinogenesis and global oncology
NIH Director's Seminar
It has been just over 50 years since the description of Burkitt Lymphoma (BL) as an unusual tumor affecting jaws of African children. Seminal discoveries linked to BL includ Epstein-Barr virus, the first human virus linked to a human cancer, the linkage of BL to Plasmodium falciparum malaria, chromosomal translocations involving c-myc and immunoglobulin promoter elements, and demonstration of rapid and curative response to chemotherapy. Dubbed the Rosetta stone of cancer, BL became a complex model for carcinogenesis involving poly-microbes, immunity and host-genetics.
Fifty years later, many fundam...
Source: Videocast - All Events - February 24, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
