Janssen Submits New Drug Application to U.S. FDA Seeking Approval of Investigational Single Tablet Combination Therapy of Macitentan and Tadalafil for Treatment of Patients with Pulmonary Arterial Hypertension (PAH)
RARITAN, NJ, May 30, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval of an investigational single tablet combination therapy of macitentan 10mg and tadalafil 40mg (M/T STCT) for the long-term treatment of pulmonary arterial hypertension (PAH, World Health Organization [WHO] Group 1) in adult patients with WHO functional class (FC) II-III.[1] The application is based on positive data from the Phase 3 A DUE study, which met its primary endpoint and demonstrated that M/T STCT si...
Source: Johnson and Johnson - May 30, 2023 Category: Pharmaceuticals Source Type: news
First Phase 3 TREMFYA ® (guselkumab) Data in Inflammatory Bowel Disease Show Positive Induction Results Among Patients with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, May 9, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new efficacy and safety data from the Phase 3 QUASAR Induction Study evaluating the investigational use of TREMFYA® (guselkumab) in adults with moderately to severely active ulcerative colitis (UC)a who had an inadequate response or intolerance to conventionalb and/or advanced therapies.1,c The data show statistically significant and clinically meaningful improvements across symptomatic and histo-endoscopic outcome measures.1 Safety data were also consistent with the known safety profile of TREMFYA in ...
Source: Johnson and Johnson - May 9, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Pope Francis will not preside over Way of the Cross event in Rome
The Vatican says Pope Francis, who was recently hospitalized for bronchitis, won’t preside over Good Friday’s late-night Way of the Cross event due to extremely cold weather in Rome. It said that instead of presiding over the torch-lit procession at the Colosseum, Francis will watch from the hotel…#vatican #popefrancis #rome #colosseumfrancis #stpetersbasilica #holyweek #cross #eastersundaymass #stpeterssquare #mass (Source: Reuters: Health)
Source: Reuters: Health - April 7, 2023 Category: Consumer Health News Source Type: news
Bird shots: Is vaccinating poultry the best defense against a deadly bird flu?
Lakeside, California—
Hilliker’s Ranch Fresh Eggs in this San Diego suburb has 30,000 chickens in three “cage-free,” open-air barns, where birds crowd the floor like rush-hour riders on a big city subway. “A cage-free aviary is a very interesting science experiment,” says Frank Hilliker, who runs the farm his
grandfather started
in 1942. He worries mightily about infections spreading through the massed birds. On his iPhone, he pulls up a list of the vaccines his chickens get: against Newcastle disease, infectious laryngotracheitis, coryza, colibacillosis, salmonella, infectious bronchitis, and fo...
Source: ScienceNOW - April 6, 2023 Category: Science Source Type: news
Pope Francis Discharged From Hospital, Leads Palm Sunday Service
MONDAY, April 3, 2023 – Pope Francis was back delivering Mass on Palm Sunday, just one day after he was released from the hospital following a three-day stay for bronchitis.
Francis, 86, celebrated in St. Peter’s Square in Rome as about 60,000... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 3, 2023 Category: General Medicine Source Type: news
Pope Francis leads Palm Sunday Mass after hospital stay
Bundled in a long, white coat and battling a hoarse voice, Pope Francis presided over Mass in St. Peter’s Square before tens of thousands of faithful on Palm Sunday, a day after he left a Rome hospital where he was treated for bronchitis. The sun broke through the clouds during the Mass, one of…#mass #rome #church #catholics #stpeterssquare #palmsundaymarks #jerusalem #christians (Source: Reuters: Health)
Source: Reuters: Health - April 2, 2023 Category: Consumer Health News Source Type: news
Pope Francis Leaves Hospital After Treatment for Bronchitis
Pope Francis on Saturday left the Rome hospital where he had been treated for a respiratory infection. ROME— Pope Francis left a Rome hospital Saturday morning after a three-night stay during which doctors treated him for bronchitis. The pope, who is 86 years old, looked tired but in good spirits…#rome (Source: Reuters: Health)
Source: Reuters: Health - April 1, 2023 Category: Consumer Health News Source Type: news
Pope Francis leaves hospital after 3-day stay for bronchitis;'Still alive,' he quips
A chipper-sounding Pope Francis was discharged Saturday from the Rome hospital where he was treated for bronchitis, quipping to journalists before being driven away that he’s “still alive.” Francis, 86, was hospitalized at Gemelli Polyclinic on Wednesday following his weekly public audience in St.…#rome #gemellipolyclinic #stpeterssquare #vatican #francisholyweek #eastermass #cross #romescolosseum #catholic #serenasubania (Source: Reuters: Health)
Source: Reuters: Health - April 1, 2023 Category: Consumer Health News Source Type: news
' I'm still alive,' Pope Francis quips as he leaves hospital
Pope Francis was discharged on Saturday from the Rome hospital where he was treated for bronchitis, quipping to journalists before being driven away: “I’m still alive.” Francis, 86, was hospitalized on Wednesday at Gemelli Polyclinic after reportedly having breathing difficulties following his…#rome #gemellipolyclinic #vatican #fiat #easter #holyweek #cross #colosseum #stpetersbasilica #catholicchurch (Source: Reuters: Health)
Source: Reuters: Health - April 1, 2023 Category: Consumer Health News Source Type: news
Pope Francis Leaves Hospital After Bronchitis Treatment
(Source: Reuters: Health)
Source: Reuters: Health - April 1, 2023 Category: Consumer Health News Source Type: news
Sick With Something That Isn ’ t COVID-19 or the Flu? Here ’ s What It Might Be
Flu season is wrapping up, and weekly COVID-19 diagnoses are declining. But if you’re currently sick with a respiratory illness, you’re not alone.
Data from the U.S. Centers for Disease Control and Prevention (CDC) show that a mixture of respiratory viruses are circulating right now, including common coronaviruses (other than SARS-CoV-2, which causes COVID-19), respiratory adenovirus, and parainfluenza (which is distinct from influenza).
All of these viruses can cause cold-like symptoms including fever, runny nose, sore throat, and cough, so “it’s very, very hard to tell the difference between any o...
Source: TIME: Health - March 20, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Disease healthscienceclimate Source Type: news
TREMFYA ® (guselkumab) Real-World Data Analyses Show Greater Treatment Persistence Than IL-17s in Both Bio-naïve and Bio-experienced Patients Living With Moderate to Severe Plaque Psoriasis
SPRING HOUSE, PENNSYLVANIA, March 17, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data, showing that initiation of TREMFYA® (guselkumab) was associated with greater treatment persistencea compared to secukinumab or ixekizumab in bio-naïve and bio-experienced patientsb living with moderate to severe plaque psoriasis (PsO), based on pairwise analysesc of real-world data.[1],[2] Additionally, in a post-hoc analysis of Phase 3 VOYAGE 2 clinical trial results, TREMFYA demonstrated durable clinical efficacy, itch relief and quality-of-life improvements in patients living with scal...
Source: Johnson and Johnson - March 17, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Lower respiratory tract infection in early childhood linked with higher risk of dying from respiratory disease as an adult, study finds
Adults who had a lower respiratory tract infection such as bronchitis or pneumonia before the age of 2 may be at higher risk of dying prematurely from respiratory disease, according to a new study. Experts say the decades-long research may not directly apply to today's kids but shows how health effects can linger over a lifetime. (Source: CNN.com - Health)
Source: CNN.com - Health - March 8, 2023 Category: Consumer Health News Source Type: news
Respiratory infections in a child could lead to death as an adult: Study
The first-of-its-kind study spanning over seven decades suggests that people who had a lower-respiratory-tract infection (LRTI), such as bronchitis or pneumonia, by the age of two were 93% more likely to die prematurely from respiratory disease as adults, regardless of the socioeconomic background or the smoking status. (Source: The Economic Times)
Source: The Economic Times - March 8, 2023 Category: Consumer Health News Source Type: news
Late-Breaking Phase 3 A DUE Data Show Investigational Single Tablet Combination Therapy of Macitentan and Tadalafil Significantly Improves Pulmonary Hemodynamics versus Monotherapy in Patients with Pulmonary Arterial Hypertension (PAH)
RARITAN, NJ, March 6, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced results from the Phase 3 A DUE study (NCT03904693), which showed an investigational once-daily, single tablet combination therapy, also known as fixed dose combination, of macitentan 10 mg and tadalafil 40 mg (M/T STCT), significantly improved pulmonary hemodynamics (blood flow through pulmonary blood vessels) versus macitentan and tadalafil monotherapies in pulmonary arterial hypertension (PAH) patients with World Health Organization (WHO) functional class (FC) II or III.[1] The data were presented today as a Late-...
Source: Johnson and Johnson - March 6, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
