Low-cost solutions incorporated in a standard surgical pathway for early breast cancer: A pilot study
We present the results of incorporation of low-cost solutions to provide a standard surgical care for early breast cancer (EBC) patients. This surgical pathway consists of a low-cost vacuum-assisted core needle biopsy, sentinel lymph node biopsy (SLNB) using low-cost methylene blue and fluorescin dyes under local anesthesia and oncoplastic breast surgery. Patients assessed as clinically node-negative axilla underwent such treatment. SLNB using low-cost dyes was performed without any complication. Oncoplastic surgical techniques were opted for in 32 patients, and the lumps were all excised with a ∼1-cm all-around margin o...
Source: Tropical Doctor - November 25, 2022 Category: Tropical Medicine Authors: Sanjay Kumar Yadav Dhananjaya Sharma Deepti Bala Sharma Arpan Mishra Pawan Agarwal Source Type: research

Low-cost solutions incorporated in a standard surgical pathway for early breast cancer: A pilot study
We present the results of incorporation of low-cost solutions to provide a standard surgical care for early breast cancer (EBC) patients. This surgical pathway consists of a low-cost vacuum-assisted core needle biopsy, sentinel lymph node biopsy (SLNB) using low-cost methylene blue and fluorescin dyes under local anesthesia and oncoplastic breast surgery. Patients assessed as clinically node-negative axilla underwent such treatment. SLNB using low-cost dyes was performed without any complication. Oncoplastic surgical techniques were opted for in 32 patients, and the lumps were all excised with a ∼1-cm all-around margin o...
Source: Tropical Doctor - November 25, 2022 Category: Tropical Medicine Authors: Sanjay Kumar Yadav Dhananjaya Sharma Deepti Bala Sharma Arpan Mishra Pawan Agarwal Source Type: research

Low-cost solutions incorporated in a standard surgical pathway for early breast cancer: A pilot study
We present the results of incorporation of low-cost solutions to provide a standard surgical care for early breast cancer (EBC) patients. This surgical pathway consists of a low-cost vacuum-assisted core needle biopsy, sentinel lymph node biopsy (SLNB) using low-cost methylene blue and fluorescin dyes under local anesthesia and oncoplastic breast surgery. Patients assessed as clinically node-negative axilla underwent such treatment. SLNB using low-cost dyes was performed without any complication. Oncoplastic surgical techniques were opted for in 32 patients, and the lumps were all excised with a ∼1-cm all-around margin o...
Source: Tropical Doctor - November 25, 2022 Category: Tropical Medicine Authors: Sanjay Kumar Yadav Dhananjaya Sharma Deepti Bala Sharma Arpan Mishra Pawan Agarwal Source Type: research

Risk of thrombosis in women with cancer undergoing controlled ovarian hyperstimulation for fertility preservation
ConclusionsWithin this small descriptive study, the incidence of thromboembolic events in women with cancer undergoing COH for fertility preservation is high. Cancer may play a greater role than COH in thrombosis risk. Ovarian cancer patients who undergo ovarian stimulation may have an increased risk compared to other cancer types. These findings may inform future, prospective studies to determine the role of thromboprophylaxis. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - November 25, 2022 Category: Reproduction Medicine Source Type: research

Systematic Review and Meta-Analysis of the Diagnostic Accuracy of the International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy in Diagnosing Breast Cancer
Discussion: There is strong evidence that the overall accuracy, sensitivity for “Atypical category considered positive” and specificity when “Suspicious or Malignant categories are considered positive” of FNAB are high when using the categories of the IAC Yokohama Reporting System, demonstrating the usefulness of FNAB in diagnosing breast cancer.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - November 22, 2022 Category: Cytology Source Type: research

Mediastinal Mass Discovered in the Second Trimester, a Rare Presentation of Hodgkin's Lymphoma in Pregnancy
Mil Med. 2022 Nov 18:usac346. doi: 10.1093/milmed/usac346. Online ahead of print.ABSTRACTNewly diagnosed malignancy during pregnancy is rare affecting approximately 1 in 1,000 pregnancies. Breast followed by hematologic malignancies are most common. Hodgkin's lymphoma (HL) is a lymphoid neoplasm which can present with lymphadenopathy or mediastinal mass and represents 6% of all malignancies diagnosed during pregnancy. Treatment involves a combination of chemotherapy with or without adjuvant radiation which poses significant challenges when diagnosed antepartum. We highlight a 28-year-old primigravida at 26 weeks gestation ...
Source: Military Medicine - November 18, 2022 Category: International Medicine & Public Health Authors: Monica M Purmalek Zachary A Kopelman Jeffery D Griffis Krista M Mehlhaff Veronica M Gonzalez-Brown Source Type: research

Comparison of p63 immunohistochemistry and shear wave elastography in the diagnosis of indeterminate breast lesions: A prospective study
Conclusion: SWE and p63 IHC are highly reliable novel modalities that demonstrate enhanced diagnostic accuracy of indeterminate breast lesions aiding in the early initiation of appropriate treatment and reducing the number of women subjected to biopsy or short-term follow-up for benign-appearing solid breast lesions. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Ranjith Kumar Sridhar R Chandru V Pavithra D Rajiv Raj Bhawna Dev Sandhya Sundaram R Ramya Source Type: research

A single centre experience in Turkey for comparison between core needle biopsy and surgical specimen evaluation results for HER2, SISH, estrogen receptors and progesterone receptors in breast cancer patients
Conclusion: ER evaluation results are reliable in deciding on needle biopsy material. PR may show the heterogeneous distribution in HER2 tumor. Thus, if PR and HER2 results in needle biopsy material are negative, assessments should be repeated in SS. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Hatice Karaman Fatma Senel Arzu Tasdemir Ipek & #214;zer Merve Dogan Source Type: research

A rare case of persistent large cystic breast tumor mimicking as malignant cystic breast cancer
We describe a rare case of persistent and large breast cyst. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Mei-Sze Teh Li-Ying Teoh Mee-Hoong See Source Type: research

Isolated trigeminal neuralgia: An early weird presentation of carcinoma breast
We report an interesting case of a 52-year-old postmenopausal female who presented with a 2-month history of headache, tingling sensation, and sharp shooting pain over the left face, followed by left facial paresthesia with pain over the maxillary region. Magnetic resonance imaging scan revealed presence of enplaque altered signal intensity soft-tissue lesion along the left 5th nerve from its origin at pons, and positron emission tomography with concurrent computed tomography showed a 2.9 cm × 2.6 cm intensely 18F-fluorodeoxyglucose-avid breast mass, in the upper outer quadrant of the right breast. Core-needle ...
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Irappa Madabhavi Malay Sarkar KS Sandeep Mitul Modi Source Type: research

High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules
CONCLUSION: This imprinting biomarker-based test can effectively distinguish malignant from benign thyroid nodules. The high PPV and NPV make the test both an excellent rule-in and rule-out diagnostic tool. With such a diagnostic performance and its technical simplicity, this novel thyroid molecular test is clinically widely applicable.PMID:36378996 | DOI:10.1200/JCO.22.00232 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - November 15, 2022 Category: Cancer & Oncology Authors: Huixiong Xu Yifeng Zhang Hongxun Wu Ning Zhou Xing Li John P Pineda Yun Zhu Huijun Fu Ming Ying Shufang Yang Jiandong Bao Lulu Yang Bingjie Zhang Lehang Guo Liping Sun Feng Lu Hanxiang Wang Ying Huang Tiantong Zhu Xiaonan Wang Qing Wei Chunjun Sheng Shen Source Type: research

High Diagnostic Accuracy of Epigenetic Imprinting Biomarkers in Thyroid Nodules
CONCLUSION: This imprinting biomarker-based test can effectively distinguish malignant from benign thyroid nodules. The high PPV and NPV make the test both an excellent rule-in and rule-out diagnostic tool. With such a diagnostic performance and its technical simplicity, this novel thyroid molecular test is clinically widely applicable.PMID:36378996 | DOI:10.1200/JCO.22.00232 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - November 15, 2022 Category: Cancer & Oncology Authors: Huixiong Xu Yifeng Zhang Hongxun Wu Ning Zhou Xing Li John P Pineda Yun Zhu Huijun Fu Ming Ying Shufang Yang Jiandong Bao Lulu Yang Bingjie Zhang Lehang Guo Liping Sun Feng Lu Hanxiang Wang Ying Huang Tiantong Zhu Xiaonan Wang Qing Wei Chunjun Sheng Shen Source Type: research

Reproducibility of the & #8220;International academy of cytology yokohama system for reporting breast cytology & #8221; & #8211; A retrospective analysis of 70 cases
Conclusions: Inter-observer agreement of three (70.48%) cytopathologists was substantial. Agreement can be improved by combining certain categories, especially “Suspicious” and “Malignant”. Technical quality limitation plays a significant role in a proportion of cases, mainly the “Atypical” and “Suspicious of malignancy” categories. Application of the IAC YSRB system in day-to-day practice will increase the inter-observer agreement. (Source: Journal of Cytology)
Source: Journal of Cytology - November 14, 2022 Category: Cytology Authors: Anup K Boler Shreosee Roy Ankita Chakraborty Arghya Bandyopadhyay Source Type: research

Cell Blocks from Ultrasound Guided Fine Needle Aspirates: Diagnostic Yield in a Series of 51 Dermatologic Lesions
Actas Dermosifiliogr. 2022 Nov 10:S0001-7310(22)00945-0. doi: 10.1016/j.ad.2022.01.052. Online ahead of print.ABSTRACTThe generation of cell blocks (CB) obtained from ultrasound-guided fine needle aspiration biopsies (USFNAB) is a well-established technique in breast and thyroid pathology, but is rarely used in dermatology. We reviewed CBs obtained from USFNAB of skin lesions, which were categorized as malignant skin tumors, benign skin tumors, inflammatory skin tumors or deposit skin diseases. The diagnostic yield of each category was compared to histopathology. The USFNAB of 51 skin lesions was processed into CBs. There ...
Source: Actas Dermo-Sifiliograficas - November 13, 2022 Category: Dermatology Authors: A Laverde-Saad L N ájera Botello I Salg üero Fernandez L Turri ón Merino G Roustan Gull ón F Alfageme Roldan Source Type: research