RSNA 2019 AI Round-Up
Shah Islam Hugh Harvey By HUGH HARVEY, MBBS and SHAH ISLAM, MBBS AI in medical imaging entered the consciousness of radiologists just a few years ago, notably peaking in 2016 when Geoffrey Hinton declared radiologists’ time was up, swiftly followed by the first AI startups booking exhibiting booths at RSNA. Three years on, the sheer number and scale of AI-focussed offerings has gathered significant pace, so much so that this year a decision was made by the RSNA organising committee to move the ever-growing AI showcase to a new space located in the lower level of the North Hall. In some ways it made sense to offe...
Source: The Health Care Blog - December 10, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Start-Ups AI Hugh Harvey Radiology RSNA RSNA 2019 RSNA19 Shah Islam Source Type: blogs

Fight Aging! Newsletter, August 19th 2019
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - August 18, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, April 15th 2019
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - April 14, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Top Digital Health Stories of 2018: From Amazon And Google To Gene-Edited Babies
Instead of mind-boggling inventions, 2018 was the year when national governments, as well as healthcare regulators, started to embrace digital health technologies at scale. The year when Google, Amazon, Apple or Microsoft competed head-to-head for the biggest chunks on the healthcare market, and when the buzzword of the year award went to the blockchain. Here’s our guide to the top digital health stories from last year. 2018: Under the spell of cosmos and microcosmos Every year, The Medical Futurist team sits down and collects the top stories of the past 12 months in healthcare. We put the novelties under the microscope,...
Source: The Medical Futurist - December 11, 2018 Category: Information Technology Authors: nora Tags: Business Future of Medicine Medical Professionals Patients Policy Makers Researchers Top Lists 2018 AI artificial intelligence artificial pancreas blockchain chatbot CRISPR deep learning diabetes digital health digital he Source Type: blogs

Fight Aging! Newsletter, December 3rd 2018
This article, however, is more of a commentary on high level strategy and the effects of regulation, coupled with a desire to forge ahead rather than hold back in the matter of treating aging, thus I concur with much more of what is said than is usually the case. For decades, one of the most debated questions in gerontology was whether aging is a disease or the norm. At present, excellent reasoning suggests aging should be defined as a disease - indeed, aging has been referred to as "normal disease." Aging is the sum of all age-related diseases and this sum is the best biomarker of aging. Aging and its diseases ar...
Source: Fight Aging! - December 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 5th 2018
In conclusion, weight cycling significantly increased life-span relative to remaining with obesity and had a similar benefit to sustained modest weight loss. Support for Oxidized Cholesterol as a Primary Cause of Atherosclerosis https://www.fightaging.org/archives/2018/11/support-for-oxidized-cholesterol-as-a-primary-cause-of-atherosclerosis/ In the paper I'll point out today, the authors provide evidence in support of the concept that it is specifically oxidized cholesterol that is the primary cause of atherosclerosis rather than the condition resulting from too much cholesterol in general. In atherosc...
Source: Fight Aging! - November 4, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Microfluidic Chips to Diagnose and Characterize Cancer: Interview with Prof. Fatih Sarioglu, Georgia Tech
Research into microfluidic devices to aid in cancer diagnosis promises huge leaps in making diagnostics easier and faster. Much of this research is focused on chips that can trap circulating tumor cells (CTCs) which are present in blood samples. CTCs are released from a primary tumor and can form metastases in other sites in the body, a process which is responsible for more than 90% of cancer-related deaths. Being able to easily detect and assess CTCs in the blood would provide clinicians with the ability to minimally-invasively diagnose cancer and provide researchers with a window on cancer metastasis and progression. At ...
Source: Medgadget - October 24, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Exclusive Oncology Source Type: blogs

Giving Consumers the Tools and Support They Need to Navigate Our Complex Healthcare System
By CINDI SLATER, MD, FACR As physicians and healthcare leaders, we are already well aware that the majority of patients do not have the information they need to make a medical decision or access to appropriate resources, so we didn’t need to hear more bad news. But that is precisely what new research once again told us this spring when a new study showed that almost half of the time, patients have no idea why they are referred to a GI specialist. While the study probably speaks to many of the communications shortcomings we providers have, across the board our patients often don’t know what care they need, or how to...
Source: The Health Care Blog - July 27, 2018 Category: Consumer Health News Authors: matthew holt Tags: Patients Physicians Health care leaders Health care technology patient-provider relationship Physician's Responsibilities Source Type: blogs

HPV Test Superior to Pap Smear for Detecting Precancerous Cervical Changes
A recent article indicated that HPV testing is superior to the Pap smear for detecting precancerous lesions of the cervical epithelium (see:HPV test is better than Pap smear at detecting precancerous cervical changes). Has the Pap smear outlived its usefulness in cancer screening programs? Below is a key passage from the article:A new study found that the HPV test was better than the Pap smear in detecting precancerous changes that can lead to cervical cancer. A test for HPV detects precancerous changes of the cervix earlier and more accurately than the Pap smear....The randomized, controlled study...showed that the human ...
Source: Lab Soft News - July 11, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Cytopathology Healthcare Innovations Medical Research Public Health Surgical Pathology Source Type: blogs

Latest Air-Powered Robot for Breast Biopsies Inside MRI Unveiled (Video)
Most breast biopsies are currently performed using ultrasound and handheld needles, guided by previously taken radiological images. The problem is that humans aren’t always perfect and what is imaged during an MRI scan or mammography may look different later under ultrasound. Performing a biopsy right inside the MRI machine may provide incredibly accurate targeting of suspect lesions. That, though, would require a robot small enough to fit near the patient inside the MRI, but more importantly, the robot can’t be influenced by the strong magnetic field and therefore can’t work using any electronics. Resear...
Source: Medgadget - July 10, 2018 Category: Medical Devices Authors: Editors Tags: Pathology Radiology Surgery Source Type: blogs

Fight Aging! Newsletter, June 18th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - June 17, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Tropical Travel Trouble 008 Total TB Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 008 Peer Reviewer Dr McBride ID physician, Wisconsin TB affects 1/3rd of the population and one patient dies every 20 seconds from TB. Without treatment 50% of pulmonary TB patients will be dead in 5 years. In low to middle income countries both TB and HIV can be ubiquitous, poor compliance can lead to drug resistance and malnourished infants are highly susceptible. TB can be very complex and this post will hopefully give you the backbone to TB m...
Source: Life in the Fast Lane - June 16, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine Genexpert meningitis TB TB meningitis Tuberculosis Source Type: blogs

PrEP: Protection against HIV in a pill?
HIV (the human immunodeficiency virus) weakens the human immune system and destroys the important cells that fight disease and infection. A person can get HIV when bodily fluids — including blood, semen, pre-seminal fluid, rectal fluids, or vaginal fluids of a person with the virus — come in contact with a mucous membrane or damaged tissue. HIV can be transmitted through breast milk, or when a contaminated needle or syringe comes into direct contact with the bloodstream. There is no cure for HIV, but with proper medical care the virus and its effects can be controlled. HIV transmission can be reduced by consistent use ...
Source: Harvard Health Blog - May 18, 2018 Category: Consumer Health News Authors: Meera Sunder, MBBS, MRCOG Tags: Health HIV Infectious diseases Source Type: blogs

Tumor Size (Size of Invasive Carcinoma) in Breast Carcinoma
Breast Carcinoma reporting;Tumor Size (Size of Invasive Carcinoma)The size of an invasive carcinoma is an important prognostic factor. The single greatest dimension of the largest invasive carcinoma is used to determine T classification The best size for AJCC T classification should use information from imaging, gross examination, and microscopic evaluation. Visual determination of size is often unreliable, as carcinomas often blend into adjacent fibrous tissue. The size by palpation of a hard mass correlates better with invasion of tumor cells into stroma with a desmoplastic response. Sizes should...
Source: Oncopathology - April 12, 2018 Category: Cancer & Oncology Source Type: blogs