Redescription of Hatschekia exigua Pearse, 1951 (Copepoda: Hatschekiidae), parasitic on the Squirrelfish Holocentrus adscensionis (Osbeck, 1765) (Actinopterygii: Holocentridae) off Cear á, Northeastern Brazil, with first description of the male
Syst Parasitol. 2024 Apr 3;101(3):27. doi: 10.1007/s11230-024-10151-6.ABSTRACTThe original description of Hatschekia exigua Pearse, 1951 neglected innumerous features of taxonomic value as well as morphometric data and illustrations. Posteriorly, other author tried to access the type material, but their poor state of preservation compromised a detailed redescription. Since then, this species is in need for new morphological data, mainly from fresh material. In the present work, three specimens of Holocentrus adscensionis from Mucuripe Bay, Fortaleza, State of Ceará, Northeastern Brazil, were parasitized by copepods on the...
Source: Systematic Parasitology - April 3, 2024 Category: Parasitology Authors: Jo ão Victor Couto Anna J úlia Pontes Caroline Vieira Feitosa Felipe Bisaggio Pereira Fabiano Paschoal Source Type: research

Heterogeneity and high prevalence of bone manifestations, and bone mineral density in congenital generalized lipodystrophy subtypes 1 and 2
ConclusionBone manifestations are prevalent, heterogeneous, and silent in CGL1 and CGL2. Osteolytic lesions are the most common, followed by osteosclerosis and pseudo-osteopoikilosis. Bone mass is high in most cases. There was no pain complaint related to bone lesions. Thus, systematic assessment of bone manifestations in CGL is essential. Studies are needed to better understand its pathogenesis and clinical consequences. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 3, 2024 Category: Endocrinology Source Type: research

IJERPH, Vol. 21, Pages 435: The Relationship between Professional Variables and Burnout Syndrome in Brazilian Dentists during the COVID-19 Pandemic
ho Sales-Peres Burnout syndrome (BS) is a highly prevalent occupational disease among dentists who, during the COVID-19 pandemic, have been at greater risk of contracting the disease, generating stress and distancing. The aim of this study was to assess the association of social conditions, professional factors and perceptions of COVID-19 with Burnout Syndrome. This was a cross-sectional study of 302 Brazilian dentists working in the clinical and private sectors. The professionals completed the Oldenburg Burnout Inventory online and answered sociodemographic and professional questions and questions related to their per...
Source: International Journal of Environmental Research and Public Health - April 3, 2024 Category: Environmental Health Authors: Marcelo Salmazo Castro Gabriela de Figueiredo Meira Rharessa Gabrielly Ferreira Mendes Ana Virg ínia Santana Sampaio Castilho Leonardo de Aguiar Trench Conrado Rodrigues Segalla Mario Vianna Vettore Silvia Helena de Carvalho Sales-Peres Tags: Article Source Type: research

In Silico Detection of Integrons and Their Relationship with Resistance Phenotype of Salmonella Isolates from a Brazilian Pork Production Chain
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - April 3, 2024 Category: Food Science Authors: Rafaela da Silva Rodrigues Nat ália Ferreira de Araujo Cibeli Viana Ricardo Seiti Yamatogi Lu ís Augusto Nero Source Type: research

Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line
This study aims to establish and characterize a new metastatic cSCC cell line derived from a Brazilian patient. A tumor biopsy was taken from a metastatic cSCC patient, immortalized, and named HCB-541 after several passages. The cytokeratin expression profile, karyotypic alterations, mutational analysis, mRNA and protein differential expression, tumorigenic capacity in xenograft models, and drug sensitivity were analyzed. The HCB-541 cell line showed a doubling time between 20 and 30  h and high tumorigenic capacity in the xenograft mouse model. The HCB-541 cell line showed hypodiploid and hypotetraploidy populations. We ...
Source: Human Cell - April 3, 2024 Category: Cytology Source Type: research

Relationship between OSA pathophysiological phenotypes and treatment response to mandibular advancement devices: a pilot study
Journal of Clinical Sleep Medicine, Ahead of Print. (Source: Journal of Clinical Sleep Medicine : JCSM)
Source: Journal of Clinical Sleep Medicine : JCSM - April 3, 2024 Category: Sleep Medicine Authors: Izabella P. Manetta Bruno B. Duarte Luciana B. Nucci Carla C. Enes 1Postgraduate Program in Health Sciences, Pontifical Catholic University of Campinas, Campinas, SP, Brazil 2Department of Otolaryngology Head and Neck Surgery, Pontifical Catholic Universi Source Type: research

A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen
CONCLUSION: Silymarin is shown in clinical testing to have significant benefits in reducing lipid peroxidation, oiliness, and PIH, and in improving key markers of skin aging. Additionally, the serum can be used alone or as an adjunctive treatment in acne therapy to further benefit aging, acne-prone skin. J Drugs Dermatol. 2024;23(4):     doi:10.36849/JDD.8120.PMID:38564394 | DOI:10.36849/JDD.8120 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Source Type: research

Assessing the negative impact of chlorantraniliprole, isoxaflutole, and simazine pesticides on phospholipid membrane models and tilapia gill tissues
Environ Pollut. 2024 Mar 31:123904. doi: 10.1016/j.envpol.2024.123904. Online ahead of print.ABSTRACTThe indiscriminate and, very often, incorrect use of pesticides in Brazil, as well as in other countries, results in severe levels of environmental pollution and intoxication of human life. Herein, we studied plasma membrane models (monolayer and bilayer) of the phospholipid Dioleoyl-sn-glycerol-3-phosphocholine (DOPC) using Langmuir films, and large (LUVs) and giant (GUVs) unilamellar vesicles, to determine the effect of the pesticides chlorantraniliprole (CLTP), isoxaflutole (ISF), and simazine (SMZ), used in sugarcane. C...
Source: Environmental Pollution - April 2, 2024 Category: Environmental Health Authors: Rafael J G Rubira Rafael R Correia Victor R G Batista Wallance M Pazin Francisco G Gonz ález Juan C Otero Giovana R Teixeira Aldo E Job Source Type: research

Effect of urbanization and water quality on microplastic distribution in Concei ção Lagoon watershed, Brazil
Environ Sci Pollut Res Int. 2024 Apr 2. doi: 10.1007/s11356-024-33029-y. Online ahead of print.ABSTRACTUrbanization in watersheds leads to the introduction of sources of microplastics and other pollutants in water bodies. However, the effect of urbanization on microplastic pollution and the relationship between microplastics and water quality are not well understood. We assessed the distribution of microplastics in tributaries urbanized, non-urbanized and in the receiving lagoon body of Conceição Lagoon watershed. The results show that urbanization significantly affects water quality but does not differentiate tributarie...
Source: Environmental Science and Pollution Research International - April 2, 2024 Category: Environmental Health Authors: Daniela Grij ó de Castro Aurea Luiza Lemes da Silva Michelle das Neves Lopes Andrea Santarosa Freire Nei Kavaguichi Leite Source Type: research

Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line
This study aims to establish and characterize a new metastatic cSCC cell line derived from a Brazilian patient. A tumor biopsy was taken from a metastatic cSCC patient, immortalized, and named HCB-541 after several passages. The cytokeratin expression profile, karyotypic alterations, mutational analysis, mRNA and protein differential expression, tumorigenic capacity in xenograft models, and drug sensitivity were analyzed. The HCB-541 cell line showed a doubling time between 20 and 30 h and high tumorigenic capacity in the xenograft mouse model. The HCB-541 cell line showed hypodiploid and hypotetraploidy populations. We fo...
Source: Cancer Control - April 2, 2024 Category: Cancer & Oncology Authors: Ana Carolina Laus Izabela Natalia Faria Gomes Aline Larissa Virginio da Silva Luciane Sussuchi da Silva Mirella Baroni Milan Silvia AparecidaTeixeira Ana Carolina Baptista Moreno Martin Let ícia do Nascimento Braga Pereira Carlos Eduardo Barbosa de Carva Source Type: research

A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen
CONCLUSION: Silymarin is shown in clinical testing to have significant benefits in reducing lipid peroxidation, oiliness, and PIH, and in improving key markers of skin aging. Additionally, the serum can be used alone or as an adjunctive treatment in acne therapy to further benefit aging, acne-prone skin. J Drugs Dermatol. 2024;23(4):     doi:10.36849/JDD.8120.PMID:38564394 | DOI:10.36849/JDD.8120 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Source Type: research

Assessing the negative impact of chlorantraniliprole, isoxaflutole, and simazine pesticides on phospholipid membrane models and tilapia gill tissues
Environ Pollut. 2024 Mar 31:123904. doi: 10.1016/j.envpol.2024.123904. Online ahead of print.ABSTRACTThe indiscriminate and, very often, incorrect use of pesticides in Brazil, as well as in other countries, results in severe levels of environmental pollution and intoxication of human life. Herein, we studied plasma membrane models (monolayer and bilayer) of the phospholipid Dioleoyl-sn-glycerol-3-phosphocholine (DOPC) using Langmuir films, and large (LUVs) and giant (GUVs) unilamellar vesicles, to determine the effect of the pesticides chlorantraniliprole (CLTP), isoxaflutole (ISF), and simazine (SMZ), used in sugarcane. C...
Source: Environmental Pollution - April 2, 2024 Category: Environmental Health Authors: Rafael J G Rubira Rafael R Correia Victor R G Batista Wallance M Pazin Francisco G Gonz ález Juan C Otero Giovana R Teixeira Aldo E Job Source Type: research

Effect of urbanization and water quality on microplastic distribution in Concei ção Lagoon watershed, Brazil
Environ Sci Pollut Res Int. 2024 Apr 2. doi: 10.1007/s11356-024-33029-y. Online ahead of print.ABSTRACTUrbanization in watersheds leads to the introduction of sources of microplastics and other pollutants in water bodies. However, the effect of urbanization on microplastic pollution and the relationship between microplastics and water quality are not well understood. We assessed the distribution of microplastics in tributaries urbanized, non-urbanized and in the receiving lagoon body of Conceição Lagoon watershed. The results show that urbanization significantly affects water quality but does not differentiate tributarie...
Source: Environmental Science and Pollution Research International - April 2, 2024 Category: Environmental Health Authors: Daniela Grij ó de Castro Aurea Luiza Lemes da Silva Michelle das Neves Lopes Andrea Santarosa Freire Nei Kavaguichi Leite Source Type: research

A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen
CONCLUSION: Silymarin is shown in clinical testing to have significant benefits in reducing lipid peroxidation, oiliness, and PIH, and in improving key markers of skin aging. Additionally, the serum can be used alone or as an adjunctive treatment in acne therapy to further benefit aging, acne-prone skin. J Drugs Dermatol. 2024;23(4):     doi:10.36849/JDD.8120.PMID:38564394 | DOI:10.36849/JDD.8120 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - April 2, 2024 Category: Dermatology Source Type: research