Suicidal ideation in adolescence: a perspective view on the role of the ventromedial prefrontal cortex - Morese R, Longobardi C.
Suicide in adolescence is a worldwide issue, and it continues to present a serious problem in terms of its prevention. Among the various aspects of suicide, a very interesting area of research is represented by suicidal ideation. Recently, neuroimaging-bas... (Source: SafetyLit)
Source: SafetyLit - April 2, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Fatigue and suicidal ideation in people with multiple sclerosis: the role of social support - Mikula P, Timkova V, Linkova M, Vitkova M, Szilasiova J, Nagyova I.
Fatigue and poor sleep quality are among the most common patient-reported problems associated with multiple sclerosis (MS). Social support, on the other hand, is often found to be positively associated with quality of life in patients with neurological dis... (Source: SafetyLit)
Source: SafetyLit - April 2, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Scoliosis Screenings by a Trained Nurse vs a Spine Surgeon Scoliosis Screenings by a Trained Nurse vs a Spine Surgeon
Is a nurse with a smartphone app as accurate as a spinal surgeon in diagnosing scoliosis among middle school students?Spine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 2, 2020 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Opioid Epidemic Continues to Wreak Havoc Among Young Children Opioid Epidemic Continues to Wreak Havoc Among Young Children
Children younger than 6 are exposed to fewer prescription narcotics now than in 2010, but the opioid epidemic continues to wreak havoc in the lives of society's most vulnerable citizens, new research shows.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 2, 2020 Category: Neurology Tags: Psychiatry News Source Type: news

From Aldous Huxley to the Beatles: how LSD has inspired art
As scientist David Nutt campaigns for drug rules to change, we look at artists who said yes to psychedelic cultureWhile the neuropsychopharmacologistDavid Nutt and colleagues campaign for rules around psychedelics to changeto aid research, such drugs have a long history in creative circles.LSD was important to the Beatles, whose song Lucy in the Sky With Diamonds is thought to be a nod to the drug, with psychedelics referred to in Day Tripper among others. LSD is also thought to have played animportant role in the creation of the album Revolver. John Lennon and George Harrison were enthusiastic about taking the drug, where...
Source: Guardian Unlimited Science - April 2, 2020 Category: Science Authors: Nicola Davis Tags: Drugs Drugs policy Culture UK news Aldous Huxley Design Susan Sarandon David Nutt Society Art and design Science The Beatles Source Type: news

We continue to pursue those that place public health at risk. With @FTC, we issued a warning letter to Neuro XPF, which sells cannabidiol (CBD) products with the misleading claim these products can mitigate, prevent, treat, diagnose, or cure #COVID19. https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/neuroxpf-606236-03312020   …
We continue to pursue those that place public health at risk. With @FTC, we issued a warning letter to Neuro XPF, which sells cannabidiol (CBD) products with the misleading claim these products can mitigate, prevent, treat, diagnose, or cure #COVID19. https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/neuroxpf-606236-03312020 … (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - April 2, 2020 Category: Medical Devices Authors: ( at SteveFDA) Source Type: news

In Some Cases, COVID-19 May Harm the Brain
THURSDAY, April 2, 2020 -- The woman worked in the airlines industry and was in her late 50s. She arrived at Henry Ford Health System in Detroit with a cough, fever and mental confusion that had arisen over the prior three days. A nasal swab test... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 2, 2020 Category: General Medicine Source Type: news

High Blood Pressure of Pregnancy Tied to Developmental Problems in Children
Pre-eclampsia was associated with a slightly increased risk of epilepsy, autism and other neurodevelopmental problems in offspring. (Source: NYT Health)
Source: NYT Health - April 2, 2020 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Preeclampsia Pregnancy and Childbirth Autism Epilepsy Ears and Hearing Intellectual Disabilities Source Type: news

GenX affects function of proteins that protect the brain
New research is part of a larger NIEHS effort to better understand PFAS chemicals. (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - April 2, 2020 Category: Environmental Health Source Type: news

Single mutation leads to big effects in autism-related gene
(NIH/National Institute of Neurological Disorders and Stroke) A new study in Neuron offers clues to why autism spectrum disorder (ASD) is more common in boys than in girls. National Institutes of Health scientists found that a single amino acid change in the NLGN4 gene, which has been linked to autism symptoms, may drive this difference in some cases. The study was conducted at NIH's National Institute of Neurological Disorders and Stroke (NINDS). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

Scientists show how parasitic infection causes seizures, psychiatric illness for some
(Virginia Tech) In a new study published in GLIA , Virginia Tech neuroscientists at the Fralin Biomedical Research Institute at VTC describe how the common Toxoplasma gondii parasite prompts the loss of inhibitory signaling in the brain by altering the behavior of nearby cells called microglia. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 2, 2020 Category: Infectious Diseases Source Type: news

Chilling concussed cells shows promise for full recovery
(University of Wisconsin-Madison) In the future, treating a concussion could be as simple as cooling the brain. That's according to research conducted by University of Wisconsin-Madison engineers, whose findings support the treatment approach at the cellular level. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

Gut communicates with the entire brain through cross-talking neurons
(University of Illinois College of Agricultural, Consumer and Environmental Sciences) You know that feeling in your gut? We think of it as an innate intuition that sparks deep in the belly and helps guide our actions, if we let it. It's also a metaphor for what scientists call the 'gut-brain axis,' a biological reality in which the gut and its microbial inhabitants send signals to the brain, and vice versa. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news

Stress thwarts our ability to plan ahead by disrupting how we use memory
(Stanford University) Pairing brain scans with virtual-navigation tasks, researchers found that people make less efficient and effective plans when stressed. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 2, 2020 Category: International Medicine & Public Health Source Type: news

COVID-19: AHA Guidance on Hypertension, Latest on Angiotensin Link COVID-19: AHA Guidance on Hypertension, Latest on Angiotensin Link
The American Heart Association advised cardiac patients to avoid medications or supplements that could raise blood pressure. Separately, new reviews explore the latest on the angiotensin connection.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - April 2, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Maintenance of neural stem cell positional identity by mixed-lineage leukemia 1
Neural stem cells (NSCs) in the developing and postnatal brain have distinct positional identities that dictate the types of neurons they generate. Although morphogens initially establish NSC positional identity in the neural tube, it is unclear how such regional differences are maintained as the forebrain grows much larger and more anatomically complex. We found that the maintenance of NSC positional identity in the murine brain requires a mixed-lineage leukemia 1 (Mll1)–dependent epigenetic memory system. After establishment by sonic hedgehog, ventral NSC identity became independent of this morphogen. Even transien...
Source: ScienceNOW - April 2, 2020 Category: Science Authors: Delgado, R. N., Mansky, B., Ahanger, S. H., Lu, C., Andersen, R. E., Dou, Y., Alvarez-Buylla, A., Lim, D. A. Tags: Development, Neuroscience r-articles Source Type: news

Facial expressions of emotion states and their neuronal correlates in mice
Understanding the neurobiological underpinnings of emotion relies on objective readouts of the emotional state of an individual, which remains a major challenge especially in animal models. We found that mice exhibit stereotyped facial expressions in response to emotionally salient events, as well as upon targeted manipulations in emotion-relevant neuronal circuits. Facial expressions were classified into distinct categories using machine learning and reflected the changing intrinsic value of the same sensory stimulus encountered under different homeostatic or affective conditions. Facial expressions revealed emotion featu...
Source: ScienceNOW - April 2, 2020 Category: Science Authors: Dolensek, N., Gehrlach, D. A., Klein, A. S., Gogolla, N. Tags: Neuroscience reports Source Type: news

Revealing animal emotions
(Source: ScienceNOW)
Source: ScienceNOW - April 2, 2020 Category: Science Authors: Girard, B., Bellone, C. Tags: Neuroscience perspective Source Type: news

How to read the face of a mouse
(Source: ScienceNOW)
Source: ScienceNOW - April 2, 2020 Category: Science Authors: Stern, P. Tags: Neuroscience twis Source Type: news

Sustaining stem cell identity
(Source: ScienceNOW)
Source: ScienceNOW - April 2, 2020 Category: Science Authors: Hines, P. J. Tags: Development, Neuroscience twis Source Type: news

Brain images may show 'cytokine storm' from COVID-19
New CT and MR images of a patient in Michigan with COVID-19 appear to show...Read more on AuntMinnie.comRelated Reading: Paraguay-trained radiologist first Miami-Dade COVID-19 death Paxerahealth launches COVID-19 tracking app RSNA to build a COVID-19 image repository Open-source AI COVID-Net targets COVID-19 on chest x-ray Wuhan nuclear medicine docs give COVID-19 safety advice (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 1, 2020 Category: Radiology Source Type: news

Some Coronavirus Patients Show Signs of Stroke, Seizures and Confusion
Doctors have observed neurological symptoms, including confusion, stroke and seizures, in a small subset of Covid-19 patients. (Source: NYT Health)
Source: NYT Health - April 1, 2020 Category: Consumer Health News Authors: Roni Caryn Rabin Tags: your-feed-science Seizures (Medical) Coronavirus (2019-nCoV) Fever Senses and Sensation Nerves and Nervous System Smell (Olfaction) Boca Raton (Fla) China Europe Germany France Wuhan (China) United States your-feed-health Source Type: news

The True Impact of Underlying Health Conditions on Coronavirus Severity
Of all of the new terms we’ve had to get accustomed to in the era of COVID-19, few are as powerful—and yet as vague—as “underlying conditions.” If you’re young and you don’t have them, you feel invincible. If you’re old and you do, you feel like a sitting duck for the coronavirus. Death and hospitalization tolls in both Wuhan, China and across Italy had already shown that the most at-risk population is people over 65 with one of a whole range of underlying ills, including cardiovascular disease, chronic lung disease, immunosuppression, diabetes, chronic liver or kidney diseas...
Source: TIME: Health - April 1, 2020 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized COVID-19 Source Type: news

How Ritalin Works in the Brain
WEDNESDAY, April 1, 2020 -- A new study dispels a common belief about how stimulants such as Ritalin and Adderall work in the brain. The drugs are usually prescribed to people with attention deficit hyperactivity disorder (ADHD), but are sometimes... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 1, 2020 Category: General Medicine Source Type: news

Aspen Neuroscience Announces $70 Million Series A Financing Led by OrbiMed to Advance Development of the First Autologous Neuron Replacement Therapy to Treat Parkinson Disease
SAN DIEGO, April 1, 2020 -- (Healthcare Sales & Marketing Network) -- Aspen Neuroscience, a private biotechnology company developing the first autologous neuron replacement therapy to treat Parkinson disease, today announced the close of its Series A fund... Regenerative Medicine, Neurology, Venture Capital Aspen Neuroscience, Parkinson, stem cell (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 1, 2020 Category: Pharmaceuticals Source Type: news

Brain Images Reveal Possible COVID-19-Related “Cytokine Storm”
Case of acute necrotizing encephalopathy could be first of many. (Source: Diagnostic Imaging)
Source: Diagnostic Imaging - April 1, 2020 Category: Radiology Authors: Whitney J. Palmer Tags: Brain MRI Infectious Diseases & Conditions/COVID-19 Source Type: news

GP surgery sends out letter asking terminally ill patients to sign DNR notices
Llynfi Surgery, in Maesteg, South Wales, sent the letter to patients with serious health conditions such as incurable cancer, motor neurone disease, and untreatable heart and lung conditions. (Source: the Mail online | Health)
Source: the Mail online | Health - April 1, 2020 Category: Consumer Health News Source Type: news

NeuroXPF - 606236 - 03/31/2020
Unapproved Products Related to the Coronavirus Disease 2019 (COVID-19) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 1, 2020 Category: Drugs & Pharmacology Authors: Center for Drug Evaluation and Research Source Type: news

Prenatal and perinatal complications in the development of psychosis: canaries in the coalmine - Cannon M, Healy C, Clarke MC, Cotter D.
Although first suggested as early as the 1930s, the study of obstetric complications as risk factors for later psychotic disorders came to the fore in the late 1980s, when proponents of the neurodevelopmental aetiological model of schizophrenia cited t... (Source: SafetyLit)
Source: SafetyLit - April 1, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Posttraumatic epilepsy in intensive care unit-treated pediatric traumatic brain injury patients - Mikkonen ED, Skrifvars MB, Reinikainen M, Bendel S, Laitio R, Hoppu S, Ala-Kokko T, Karppinen A, Raj R.
OBJECTIVE: Posttraumatic epilepsy (PTE) is a well-described complication of traumatic brain injury (TBI). The majority of the available data regarding PTE stem from the adult population. Our aim was to identify the clinical and radiological risk factors as... (Source: SafetyLit)
Source: SafetyLit - April 1, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Early adult mental health, functional and neuropsychological outcomes of young people who have reported psychotic experiences: a 10-year longitudinal study - Carey E, Gillan D, Healy C, Dooley N, Campbell D, McGrane J, O'Neill A, Coughlan H, Clarke M, Kelleher I, Cannon M.
BACKGROUND: Psychotic experiences (PE) are highly prevalent in childhood and are known to be associated with co-morbid mental health disorders and functional difficulties in adolescence. However, little is known about the long-term outcomes of young people... (Source: SafetyLit)
Source: SafetyLit - April 1, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Image of the Day: A Mouse Brain Slice Becomes Art
A fluorescent image of murine hippocampal cells is the winning microscopy image from more than 400 submissions from 65 countries for Olympus's 2019 Image of the Year Award. (Source: The Scientist)
Source: The Scientist - April 1, 2020 Category: Science Tags: Image of the Day Source Type: news

Antisense Oligonucleotides in Neurodegenerative Diseases Antisense Oligonucleotides in Neurodegenerative Diseases
Learn about the mechanisms of action and potential uses of antisense oligonucleotide-based therapies in polyglutamine disorders.Brain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 1, 2020 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Pain, Opioid Therapy, and Survival: A Needed Discussion Pain, Opioid Therapy, and Survival: A Needed Discussion
This article explores the association between opioid therapy and disease progression, and the complexity it adds regarding pain management.Pain (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 1, 2020 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

fMRI finds reason for impulsive binge drinking
Functional MR images (fMRI) have uncovered decreased connectivity from excessive...Read more on AuntMinnie.comRelated Reading: MRI data show smoking, alcohol age the brain Brain MRI may predict alcohol abuse in teens PET, fMRI shed light on alcohol's effects on brain MRI links lifestyle factors to stroke, dementia risk fMRI shows what makes an angry drunk (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - April 1, 2020 Category: Radiology Source Type: news

Zika as Cancer Buster?
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose. (Source: The Scientist)
Source: The Scientist - April 1, 2020 Category: Science Tags: The Literature Source Type: news

Inherited mutation can predispose children to a type of brain tumor
(St. Jude Children's Research Hospital) Collaboration co-led by researchers at St. Jude Children's Research Hospital discovers a novel predisposition gene in pediatric medulloblastoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2020 Category: Cancer & Oncology Source Type: news

Brain tumors in children: Hereditary genetic defect destabilizes protein regulation
(German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)) The causes of 40 percent of all cases of certain medulloblastoma - dangerous brain tumors affecting children - are hereditary. These are the findings of a recent genetic analysis carried out by scientists from the Hopp Children's Cancer Center (KiTZ), the European Molecular Biology Laboratory (EMBL) and numerous colleagues around the world, which have just been published in the scientific journal Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2020 Category: Cancer & Oncology Source Type: news

Understanding brain tumors in children
(European Molecular Biology Laboratory) The causes of 40% of all cases of certain medulloblastomas -- dangerous brain tumors affecting children -- are hereditary. These are the findings of a recent genetic analysis carried out by scientists from the European Molecular Biology Laboratory (EMBL) and numerous colleagues around the world. A genetic defect that occurs in 15% of these children plays a key role by destabilizing the production of proteins. The researchers suspect that protein metabolism defects could be a previously underestimated cause of other types of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2020 Category: Cancer & Oncology Source Type: news

Mayo Clinic research finds spina bifida surgery before birth restores brain structure
(Mayo Clinic) Surgery performed on a fetus in the womb to repair defects from spina bifida triggers the body's ability to restore normal brain structure, Mayo Clinic research discovered. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 1, 2020 Category: International Medicine & Public Health Source Type: news

How dopamine drives brain activity
(Massachusetts Institute of Technology) Using a specialized magnetic resonance imaging (MRI) sensor that can track dopamine levels, MIT neuroscientists have discovered how dopamine released deep within the brain influences distant brain regions. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 1, 2020 Category: International Medicine & Public Health Source Type: news

Skull scans reveal evolutionary secrets of fossil brains
(Arizona State University) Three-million-year old brain imprints in fossil skulls of the species Australopithecus afarensis (famous for 'Lucy' and 'Selam' from Ethiopia) shed new light on the evolution of brain growth and organization. In Science Advances, a new study reveals that while Lucy's species had an ape-like brain structure, the brain took longer to reach adult size. Australopithecus afarensis infants may have had a long dependence on caregivers, a human-like trait. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 1, 2020 Category: International Medicine & Public Health Source Type: news

Tracking tau
(University of California - Santa Barbara) In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a team player -- it maintains structure and stability within neurons, and it helps with transport of nutrients from one part of the cell to another. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 1, 2020 Category: International Medicine & Public Health Source Type: news

JONED, a new online free-access journal open in the field of neuroeducation
(University of Barcelona) Building bridges between the science and education communities to contribute and improve the current didactic experiences is the goal of the Journal of Neuroeducation (JONED), a new online free-access journal open to the scientific community at a national and international level promoted by the Chair of Neuroeducation of the University of Barcelona ( Edu1st), a pioneer initiative in Spain led by the lecturers David Bueno and Anna For é s (UB). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 1, 2020 Category: International Medicine & Public Health Source Type: news

Study: Therapy by phone is effective for depression in people with Parkinson's
(American Academy of Neurology) Depression is common in people with Parkinson's disease and contributes to faster physical and mental decline, but it is often overlooked and undertreated. The good news is that participating in cognitive-behavioral therapy by telephone may be effective in reducing depression symptoms for people with Parkinson's, according to a study published in the April 1, 2020, online issue of Neurology ® , the medical journal of the American Academy of Neurology. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 1, 2020 Category: International Medicine & Public Health Source Type: news

Online NeurekaTM challenge launches to crowdsource EEG solutions for epilepsy
(Novela Neurotech) A collaboration between Novela Neurotech and NeuroTechX launches a month-long challenge with cash prize for everyone working from home. The challenge aims to harness a new generation of AI and online big data resources to develop better seizure prediction algorithms using scalp EEG signals. Winning solutions will be made available online and open-sourced to encourage further improvements. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 1, 2020 Category: International Medicine & Public Health Source Type: news

Babies with brain tumors could benefit from targeted treatment
(Institute of Cancer Research) Brain cancer in infants is biologically distinct from other childhood brain tumors and could be successfully treated with targeted drugs, a new study has shown. In the largest and most comprehensive study of infant gliomas to date, scientists found that these tumors are molecularly different from those in older children, helping explain why they tend to be less aggressive. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2020 Category: Cancer & Oncology Source Type: news

CVD May Play Role in Link Between Air Pollution, Dementia
Heart failure, ischemic heart disease, stroke may contribute to link between air pollution and dementia (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - April 1, 2020 Category: Psychiatry Tags: Cardiology, Family Medicine, Geriatrics, Internal Medicine, Neurology, Psychiatry, Pulmonology, Journal, Source Type: news

Mayo Clinic research finds spina bifida surgery before birth restores brain structure
ROCHESTER, Minn. -- Surgery performed on a fetus in the womb to repair defects from spina bifida triggers the body's ability to restore normal brain structure, Mayo Clinic research discovered. Research by Rodrigo Ruano, M.D., Ph.D., chair of Mayo Clinic's Division of Maternal and Fetal Medicine, finds that fetal surgery to correct congenital spinal cord [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - April 1, 2020 Category: Hospital Management Source Type: news

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CNN's Dr. Sanjay Gupta looks back on the life of his friend and colleague Dr. James Goodrich, the renowned neurosurgeon best known for separating conjoined twins. (Source: CNN.com - Health)
Source: CNN.com - Health - March 31, 2020 Category: Consumer Health News Source Type: news