How Romantic Obsession Alters The Brain And Makes You Manic (M)
Find out why early love can mimic symptoms of obsessive-compulsive disorder in the brain. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - February 14, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Neuroscience Social psychology subscribers-only Source Type: blogs

Best books on brain health and cognitive fitness according to ChatSpot and ChatGPT
Out of curiosity we queried a couple popular AI chatbots, ChatSpot and ChatGPT free versions, about the best books in a couple of key topics we discuss a lot in this blog. Here are the fascinating results, and some brief commentary at the end. (Links open corresponding Amazon book pages.) Best books on brain health, per ChatSpot: There are several great books on brain health that provide valuable insights and practical tips. Here are some highly recommended ones: 1. “The Brain That Changes Itself” by Norman Doidge: This book explores the concept of neuroplasticity and how the brain can rewire itself to overcome various...
Source: SharpBrains - February 14, 2024 Category: Neuroscience Authors: SharpBrains Tags: Books Education & Lifelong Learning brain-books Brain-Fitness brain-health-books ChatGPT ChatSpot cognitive-fitness cognitive-health-books neuroplasticity Source Type: blogs

Allostatic Load as a Correlate of Aging
Allostatic load is the concept of wear and tear on the body that emerges from stresses via overactivation of the neuroendocrine system. Causative stresses can range from starvation to psychological stress to a high burden of age-related dysfunction. At some point reactions to stress that are compensatory tip over into being themselves damaging. Thus one could expect allostatic load to correlate with degenerative aging and risk of mortality to at least some degree. In practice, however, there is little agreement on how to measure allostatic load, particularly in human patients, which makes it hard to compare results from st...
Source: Fight Aging! - February 14, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Why are " Love Languages " so popular, when they're completely inaccurate?
I joined an online dating site a few months ago.1 Besides being asked about my sun, moon, and rising signs (?), I was puzzled by the following question.2My love language? I ' m supposed to choose only one answer? Gary Chapman has been apastor at Calvary Baptist Church in Winston-Salem, NC for 50 years. In 1992, he published a book based on his experience of advising heterosexual couples on the best ways to have a harmonious marriage. His notion of 5 Love Languages is based on conservative Christian gender roles, although subsequent editions are“less blatantly misogynistic.” Nonetheless, the popularity of his ideas...
Source: The Neurocritic - February 14, 2024 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

Reviewing the Data on Human Use of Rapamycin
Rapamycin and some of the later rapalog derivatives such as everolimus, all of which function via inhibition of mTOR, are arguably the best of the present crop of geroprotective drugs capable of modestly slowing aging and extending life in animal studies. The effects of rapamycin in mice are robust and repeatable, though never as large as we'd all like them to be. Like many of the other interventions that modestly slow aging in animal models these small molecule drugs mimic some of the effects of calorie restriction, and likely produce benefits largely through increased efficiency of the cell maintenance processes of autop...
Source: Fight Aging! - February 13, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Trial By Error: Leading FND Site Confirms Criticisms on Prevalence Outlined in Our Letter to Neurology Journal
By David Tuller, DrPH In two recent posts, here and here, I wrote about our letter on inflated prevalence claims for functional neurological disorder (FND) and about the response from the authors of the study we criticized. The 2021 article in NeuroImage: Clinical, “Neuroimaging in functional neurological disorder: state of the field and research agenda,” asserted … Trial By Error: Leading FND Site Confirms Criticisms on Prevalence Outlined in Our Letter to Neurology Journal Read More » (Source: virology blog)
Source: virology blog - February 13, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized FND functional neurological disorder Jon Stone neuroImage: clinical Source Type: blogs

The Skin Microbiome in Skin Aging
In comparison to presently expanding studies of the gut microbiome, much less effort is directed towards the skin microbiome in the context of aging. Given the existence of the sizeable and vocal cosmetics industry, I'm sure that will change in the years ahead, however. For now, research into mechanisms by which the skin microbiome might change with age and in turn affect the aging of skin remains lagging somewhat behind the equivalent programs focused on intestinal microbial populations and their effects on the aging body and brain. The interplay between microbes and the skin barrier holds pivotal significance in...
Source: Fight Aging! - February 13, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The 2024 Word of the Year: Missense
By MIKE MAGEE Not surprisingly, my nominee for “word of the year” involves AI, and specifically “the language of human biology.” As Eliezer Yudkowski, the founder of the Machine Intelligence Research Institute and coiner of the term “friendly AI” stated in Forbes: “Anything that could give rise to smarter-than-human intelligence—in the form of Artificial Intelligence, brain-computer interfaces, or neuroscience-based human intelligence enhancement – wins hands down beyond contest as doing the most to change the world. Nothing else is even in the same league.”  Perhaps the ...
Source: The Health Care Blog - February 13, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Tech Biology Crispr DNA Mike Magee Source Type: blogs

Exploring neurodivergence: a specialist psychiatrist ’ s journey
I read about a psychiatrist whose interests are in medical ethics and the improvement of medical care for youth coping with the complexities related to neurodivergence and significant mental health conditions. Additionally, she specializes in work with twice-exceptional (2e) individuals – those with exceptional talents and abilities who also navigate challenges related to disabilities or Read more… Exploring neurodivergence: a specialist psychiatrist’s journey originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 12, 2024 Category: General Medicine Authors: Tags: Conditions Psychiatry Source Type: blogs

CIO Podcast – Episode 68: Health IT and Leadership with 2024 CHIME CIO of the Year Shafiq Rab
For the 68th episode of the CIO podcast hosted by Healthcare IT Today, we are talking to Shafiq Rab, MD, Chief Digital Officer, System CIO and EVP at Tufts Medicine, who just recently won 2024 CHIME CIO of the Year! As the CIO of the Year, we are very excited to pick his brain on health IT and leadership, so we kick this episode off by asking Rab what his health IT top 3 are and why. Then we discuss a time Rab failed and what he was able to learn from it. Next, we get into the award of 2024 CHIME CIO of the Year and how it felt to be honored with this incredible achievement. We then move on to discussing the ongoing projec...
Source: EMR and HIPAA - February 12, 2024 Category: Information Technology Authors: John Lynn Tags: Analytics/Big Data C-Suite Leadership Healthcare CIO Podcasts Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops 2024 CHIME CIO of the Year CIO Leadership Health IT Healthcare AI Healthcare Data Lake Healthcare Lead Source Type: blogs

What Does an Immunologist Do?
This post is part of a miniseries on the immune system. Be sure to check out the other posts in this series that you may have missed. Immunology is the study of the immune system, including all the cells, tissues, and organs that work together to protect you from germs. A person who studies immunology is called an immunologist, and there are three types: Researchers, who study the immune system in the laboratory to understand how it works or how it can go awry and find new treatments for immune system-related diseases Doctors, who diagnose and care for patients with diseases related to the immune system, such as ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - February 12, 2024 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Injury and Illness Immunology Miniseries Infectious Diseases Medicines Microbes Research Roundup Source Type: blogs

Oxidative Stress and Cellular Senescence in Alzheimer's Disease
In this paper, the authors discuss the overlap between oxidative stress and growing numbers of senescent cells in the brain. Both are thought to contribute to neurodegenerative conditions such as Alzheimer's disease. The aging of the brain is complex, a web of interacting processes, causes, and consequences. It has proven to be difficult to determine which processes are more or less important; the only efficient way forward is to come up with interventions that remove just one contributing factor with minimal side-effects. That is now possible for senescent cells, and clinical trials are underway, but manipulation of oxida...
Source: Fight Aging! - February 12, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Trial By Error: Unconvincing Response to Letter on FND Prevalence Inflation
By David Tuller, DrPH As I wrote in a post the other day, the journal NeuroImage: Clinical has just published a letter from a group I organized about the misrepresentation of findings regarding the prevalence of functional neurological disorder (FND). They have also published a response from the authors of the article we criticized. The … Trial By Error: Unconvincing Response to Letter on FND Prevalence Inflation Read More » (Source: virology blog)
Source: virology blog - February 12, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, February 12th 2024
In conclusion, frailty is a dynamic process, and improved frailty and remaining robust are significantly associated with lower risk of all-cause mortality and cardiovascular death in older people. « Back to Top Greater Individual Wealth Correlates with Longer Life Expectancy https://www.fightaging.org/archives/2024/02/greater-individual-wealth-correlates-with-longer-life-expectancy/ Individual wealth correlates with life expectancy, with an effect size that is in the same ballpark as those related to lifestyle choices involving exercise, diet, and consequences thereof. It remains unclear...
Source: Fight Aging! - February 11, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs