Outcome and Prognostic Factors of Childhood Diffuse Brainstem Glioma
ConclusionThe radiation therapy fractionation schedule did not influence the survival. Low grade histology was a possible favorable prognostic factor of progression-free survival in pediatric brainstem glioma patients. (Source: Cancer Research and Treatment)
Source: Cancer Research and Treatment - April 29, 2005 Category: Cancer & Oncology Tags: Original Article Source Type: research
Permanent Iodine-125 Implants in the Treatment of Low-Grade Gliomas
We report a retrospective study on the use of the permanent iodine-125 (125I) implants in the management of low-grade gliomas. From July 1988 to July 1997, 16 patients with low-grade gliomas underwent permanent 125I implants in the management of their lesions. There were 7 males and 9 females ranging in age from 4 to 48 years (mean 19). The location was in the cerebral hemisphere in 7 patients, brainstem in 5 patients and thalamus/basal ganglia in 4 patients. Prior to brachytherapy, 9 patients underwent surgical resection and 7 patients underwent stereotactic biopsy procedures. Fourteen patients were treated as part of the...
Source: Journal of Radiosurgery - September 1, 2000 Category: Radiology Source Type: research
Interstitial irradiation with stereotactically implanted I-125 seeds for the treatment of cerebral glioma
Abstract
Owing to its low rate of side effects and its high efficacy, interstitial irradiation with low-activity seeds should be the first therapeutic step in small (maximal diameter 40 mm), well-circumscribed, lowgrade gliomas affecting the brain stem, other midline structures, or eloquent cerebral areas. In anaplastic gliomas, a therapeutic schedule using low-activity seeds and combining interstitial irradiation with radiotherapy (reduced boost dose of 1530 Gy) seems to be more effective than interstitial irradiation alone. Compared with interstitial irradiation with high-activity seeds, this combined...
Source: Critical Reviews in Neurosurgery - April 1, 1999 Category: Neurosurgery Source Type: research
