Dosimetric impact of bone marrow sparing for robustly optimized IMPT for locally advanced cervical cancer
Standard treatment of locally advanced cervical cancer (LACC) combines external beam radiotherapy, cisplatin-based concurrent chemotherapy, and image-guided brachytherapy [1]. Although this treatment combination provides a good clinical outcome in terms of local and pelvic tumor control [2,3], it is associated with a high incidence of morbidities, including gastrointestinal (GI) and genitourinary (GU) toxicities as well as hematologic toxicity (HT) [4,5]. HT, and more specifically radiation-induced lymphopenia, has been associated with a poorer prognosis on overall survival [6,7]. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - March 10, 2024 Category: Radiology Authors: S.C. Kuipers, J. Godart, A. Corbeau, S. Breedveld, J.W.M. Mens, S.M. de Boer, R.A. Nout, M.S. Hoogeman Tags: Original Article Source Type: research
Very accelerated partial breast irradiation in 1 or 2 days: Late toxicity and early oncological outcome of the GEC-ESTRO VAPBI cohort
CONCLUSIONS: VAPBI based on 1 or ≥2 days of MIBT represents an attractive de-escalation of irradiation approach for low-risk breast cancer. Late toxicity profile appears acceptable while early oncological outcome shows encouraging local control. Longer follow-up is warranted in order to confirm these preliminary results.PMID:38460552 | DOI:10.1016/j.radonc.2024.110217 (Source: Cancer Control)
Source: Cancer Control - March 9, 2024 Category: Cancer & Oncology Authors: Jean-Michel Hannoun-Levi Marta Gimeno Morales Jocelyn Gal Javier Anchuelo Jose-Luis Guinot Miren Gastanaga Norbert Meszaros Csaba Polgar Vratislav Strnad Renaud Schiappa Cristina Gutierrez Source Type: research
Very accelerated partial breast irradiation in 1 or 2 days: Late toxicity and early oncological outcome of the GEC-ESTRO VAPBI cohort
CONCLUSIONS: VAPBI based on 1 or ≥2 days of MIBT represents an attractive de-escalation of irradiation approach for low-risk breast cancer. Late toxicity profile appears acceptable while early oncological outcome shows encouraging local control. Longer follow-up is warranted in order to confirm these preliminary results.PMID:38460552 | DOI:10.1016/j.radonc.2024.110217 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 9, 2024 Category: Radiology Authors: Jean-Michel Hannoun-Levi Marta Gimeno Morales Jocelyn Gal Javier Anchuelo Jose-Luis Guinot Miren Gastanaga Norbert Meszaros Csaba Polgar Vratislav Strnad Renaud Schiappa Cristina Gutierrez Source Type: research
Effects of pain management using nonsteroidal anti-inflammatory drug suppositories during brachytherapy for cervical cancer: A single-center prospective observational study
This study aimed to investigate the effects of pain management during intracavitary brachytherapy using nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen suppositories. (Source: Brachytherapy)
Source: Brachytherapy - March 9, 2024 Category: Cancer & Oncology Authors: Yuko Matsuda, Yusuke Nagamine, Tomoya Irie, Takahisa Goto Tags: Original Article Source Type: research
Cancers, Vol. 16, Pages 1074: Current and Emerging Radiotherapy Options for Uveal Melanoma
This article examines the dosimetric properties, targeting capabilities, and outcomes of these approaches. The several modalities examined herein have differing attributes and it may be that no single approach would be considered optimal for all patients and all lesion characteristics. (Source: Cancers)
Source: Cancers - March 6, 2024 Category: Cancer & Oncology Authors: Oleksii Semeniuk Esther Yu Mark J. Rivard Tags: Review Source Type: research
Cancers, Vol. 16, Pages 1071: Immuno-Molecular Targeted Therapy Use and Survival Benefit in Patients with Stage IVB Cervical Carcinoma in Commission on Cancer & reg;-Accredited Facilities in the United States
Conclusions: IMT was associated with a consistent survival benefit in real-world patients with stage IVB cervical cancer. (Source: Cancers)
Source: Cancers - March 6, 2024 Category: Cancer & Oncology Authors: Collin A. Sitler Chunqiao Tian Chad A. Hamilton Michael T. Richardson John K. Chan Daniel S. Kapp Charles A. Leath Yovanni Casablanca Christina Washington Nicole P. Chappell Ann H. Klopp Craig D. Shriver Christopher M. Tarney Nicholas W. Bateman Thomas P. Tags: Article Source Type: research
Percutaneous interstitial brachytherapy ablation for targeting oligometastatic gynecologic cancers
Treatment of recurrent oligometastatic gynecologic malignancy may involve targeted surgery, thermal ablation, or CT-guided high-dose-rate interstitial brachytherapy ablation (CT-HDR-IBTA). The purpose of this study was to describe the safety and efficacy of CT-HDR-IBTA for oligometastatic gynecologic malignancies. (Source: Brachytherapy)
Source: Brachytherapy - March 6, 2024 Category: Cancer & Oncology Authors: Tiffany S. Lai, Alex Francoeur, Erica Manrriquez, Puja Venkat, Albert Chang, Michael Douek, Simin Bahrami, Steven S. Raman, Sanaz Memarzadeh Source Type: research
Less than whole uterus irradiation for patients with locally advanced cervical cancer
CONCLUSIONS: Including less than the whole uterus for definitive cervix cancer IMRT does not seem to compromise local control. Less than whole uterus irradiation could be considered for carefully selected cervix cancer patients to decrease bowel dose and possible treatment-related toxicity.PMID:38438017 | DOI:10.1016/j.radonc.2024.110199 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: Caressa Hui Agnes Ewongwo Maria G Mendoza Margaret M Kozak Scott Jackson Jie Fu Elizabeth Kidd Source Type: research
Radiation Therapy Practice Patterns for Treatment of Curative Breast Cancer in a Large Tertiary Health Care System
CONCLUSIONS: This study of a diverse cohort of patients with breast cancer failed to identify treatment differences associated by race. The study found an association between age and hypofractionation.PMID:38435966 | PMC:PMC10906153 | DOI:10.1016/j.adro.2023.101436 (Source: Adv Data)
Source: Adv Data - March 4, 2024 Category: Epidemiology Authors: Bhargava Chitti Dimitre G Stefanov Louis Potters Janna Andrews Source Type: research
Prospective Evaluation of Automated Contouring for CT-Based Brachytherapy for Gynecologic Malignancies
CONCLUSIONS: Automated contouring is useful and accurate in clinical practice. Auto-contouring OARs streamlines radiation treatment workflows and decreases time required to design and approve gynecologic brachytherapy plans.PMID:38435965 | PMC:PMC10906166 | DOI:10.1016/j.adro.2023.101417 (Source: Adv Data)
Source: Adv Data - March 4, 2024 Category: Epidemiology Authors: Abigayle C Kraus Zohaib Iqbal Rex A Cardan Richard A Popple Dennis N Stanley Sui Shen Joel A Pogue Xingen Wu Kevin Lee Samuel Marcrom Carlos E Cardenas Source Type: research
Less than whole uterus irradiation for patients with locally advanced cervical cancer
CONCLUSIONS: Including less than the whole uterus for definitive cervix cancer IMRT does not seem to compromise local control. Less than whole uterus irradiation could be considered for carefully selected cervix cancer patients to decrease bowel dose and possible treatment-related toxicity.PMID:38438017 | DOI:10.1016/j.radonc.2024.110199 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: Caressa Hui Agnes Ewongwo Maria G Mendoza Margaret M Kozak Scott Jackson Jie Fu Elizabeth Kidd Source Type: research
Long-term results of intraoperative multicatheter breast implant (IOMBI) for accelerated partial breast irradiation (APBI) on early breast cancer patients
CONCLUSION: IOMBI&PHDRBT program reports excellent long-term oncological outcomes, with a reduction from unnecessary irradiation exposure which translates into low long-term toxicity and good cosmesis outcomes, especially on well-selected APBI patients.PMID:38432310 | DOI:10.1016/j.radonc.2024.110193 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 3, 2024 Category: Radiology Authors: Marta Gimeno-Morales Rafael Mart ínez-Monge Adriana Martinez-Lage Paola Anna Jablonska Javier Blanco Fernando Mart ínez-Regueira Natalia Rodriguez-Spiteri Bego ña Olartecoechea Luis Ramos Luis Pina Insausti Arlette Elizalde Marta Abengozar Mauricio Cam Source Type: research
Combined photodynamic therapy and transpupillary thermotherapy for small choroidal melanoma
CONCLUSION: Combined PDT and TTT achieved 81% tumour control in this study while preserving visual acuity. However, higher rates of local recurrence compared with brachytherapy warrant close follow-up to identify recurrences early.PMID:38431268 | DOI:10.1016/j.jcjo.2024.02.001 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - March 2, 2024 Category: Opthalmology Authors: Olivia J Rolfe Andrew L Stark Hayley R Hamilton Matthew D'Mellow Jane M Palmer Lindsay A McGrath Sunil K Warrier William J Glasson Source Type: research
Combined photodynamic therapy and transpupillary thermotherapy for small choroidal melanoma
CONCLUSION: Combined PDT and TTT achieved 81% tumour control in this study while preserving visual acuity. However, higher rates of local recurrence compared with brachytherapy warrant close follow-up to identify recurrences early.PMID:38431268 | DOI:10.1016/j.jcjo.2024.02.001 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - March 2, 2024 Category: Opthalmology Authors: Olivia J Rolfe Andrew L Stark Hayley R Hamilton Matthew D'Mellow Jane M Palmer Lindsay A McGrath Sunil K Warrier William J Glasson Source Type: research
Combined photodynamic therapy and transpupillary thermotherapy for small choroidal melanoma
CONCLUSION: Combined PDT and TTT achieved 81% tumour control in this study while preserving visual acuity. However, higher rates of local recurrence compared with brachytherapy warrant close follow-up to identify recurrences early.PMID:38431268 | DOI:10.1016/j.jcjo.2024.02.001 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - March 2, 2024 Category: Opthalmology Authors: Olivia J Rolfe Andrew L Stark Hayley R Hamilton Matthew D'Mellow Jane M Palmer Lindsay A McGrath Sunil K Warrier William J Glasson Source Type: research
