Evaluating outcomes and toxicities for a newly implemented MRI-based brachytherapy program for cervical cancer
CONCLUSION: MRI-based brachytherapy demonstrates excellent local control and acceptable rates of high-grade morbidity. These results are possible in our population with relatively large volume primary tumors and extensive local disease.PMID:38492475 | DOI:10.1016/j.ygyno.2024.03.003 (Source: Cancer Control)
Source: Cancer Control - March 16, 2024 Category: Cancer & Oncology Authors: Dylan H Ross Kayeromi Gomez Grant Harmon Michael L Mysz Steven M Shea Ari Goldberg Margaret Liotta Ronald Potkul Abigail Winder Brian Lee Jacob Jackson John C Roeske William Small Matthew M Harkenrider Source Type: research
Evaluating outcomes and toxicities for a newly implemented MRI-based brachytherapy program for cervical cancer
CONCLUSION: MRI-based brachytherapy demonstrates excellent local control and acceptable rates of high-grade morbidity. These results are possible in our population with relatively large volume primary tumors and extensive local disease.PMID:38492475 | DOI:10.1016/j.ygyno.2024.03.003 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 16, 2024 Category: Cancer & Oncology Authors: Dylan H Ross Kayeromi Gomez Grant Harmon Michael L Mysz Steven M Shea Ari Goldberg Margaret Liotta Ronald Potkul Abigail Winder Brian Lee Jacob Jackson John C Roeske William Small Matthew M Harkenrider Source Type: research
Evaluating outcomes and toxicities for a newly implemented MRI-based brachytherapy program for cervical cancer
CONCLUSION: MRI-based brachytherapy demonstrates excellent local control and acceptable rates of high-grade morbidity. These results are possible in our population with relatively large volume primary tumors and extensive local disease.PMID:38492475 | DOI:10.1016/j.ygyno.2024.03.003 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 16, 2024 Category: Cancer & Oncology Authors: Dylan H Ross Kayeromi Gomez Grant Harmon Michael L Mysz Steven M Shea Ari Goldberg Margaret Liotta Ronald Potkul Abigail Winder Brian Lee Jacob Jackson John C Roeske William Small Matthew M Harkenrider Source Type: research
Treatment intensification strategies for men undergoing definitive radiotherapy for high-risk prostate cancer
ConclusionTreatment intensification using a combination of EBRT, advanced hormonal therapies, and brachytherapy may improve patient outcomes and survival in men with high-risk prostate cancer. Shared decision-making between patients and multidisciplinary teams of radiation oncologists, urologists, and medical oncologists is essential for personalizing care in this setting and deciding which strategies make sense for individual patients. (Source: World Journal of Urology)
Source: World Journal of Urology - March 16, 2024 Category: Urology & Nephrology Source Type: research
Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients
CONCLUSION: All types of therapy were effective and well received. HDR-BT caused the least late toxicities, especially GI.PMID:38488901 | DOI:10.1007/s00066-024-02222-w (Source: Cancer Control)
Source: Cancer Control - March 15, 2024 Category: Cancer & Oncology Authors: Matthias Moll Elisabeth Nechvile Christian Kirisits Oxana Komina Thomas Pajer Bettina Kohl Marcin Miszczyk Joachim Widder Tomas-Hendrik Knocke-Abulesz Gregor Goldner Source Type: research
Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients
ConclusionAll types of therapy were effective and well received. HDR-BT caused the least late toxicities, especially GI. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 15, 2024 Category: Cancer & Oncology Source Type: research
Enhanced outcomes in residual or recurrent craniopharyngioma: evaluating combined gamma knife and phosphorus-32 brachytherapy
ConclusionThe combination of gamma knife and phosphorus-32 brachytherapy presents a viable, minimally invasive alternative for treating residual and recurrent craniopharyngioma. It offers high tumor control and functional improvement rates, suggesting its potential as a preferred strategy in some instances. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - March 15, 2024 Category: Cancer & Oncology Source Type: research
A Randomized Trial Comparing Quality of Life After LDR or HDR Prostate Brachytherapy Boost with Pelvic External Beam Radiation Therapy
To compare health-related Quality of Life (QoL) in urinary, bowel and sexual domains after combined external beam radiotherapy (EBRT) and either low dose rate (LDR) or high dose rate (HDR) prostate brachytherapy (BT). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 15, 2024 Category: Radiology Authors: Juanita Crook, Nikitha Moideen, Greg Arbour, Felipe Castro C ánovas, Cynthia Araujo, Deidre Batchelar, Ross Halperin, Michelle Hilts, David Kim, David Petrik, Jim Rose, JC Cheng, Francois Bachand Tags: Clinical Investigation Source Type: research
A Randomized Trial Comparing Quality of Life After Low-Dose Rate or High-Dose Rate Prostate Brachytherapy Boost With Pelvic External Beam Radiation Therapy
To compare health-related quality of life (QoL) in urinary, bowel, and sexual domains after combined external beam radiation therapy (EBRT) and either low-dose rate (LDR) or high-dose rate (HDR) prostate brachytherapy (BT). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 15, 2024 Category: Radiology Authors: Juanita Crook, Nikitha Moideen, Greg Arbour, Felipe Castro, Cynthia Araujo, Deidre Batchelar, Ross Halperin, Michelle Hilts, David Kim, David Petrik, Jim Rose, J.C. Cheng, Francois Bachand Tags: CLINICAL INVESTIGATION Source Type: research
Local treatment of ipsilateral breast cancer recurrences: comparison of alternative therapeutic options
Magy Onkol. 2024 Mar 14;68(1):86-88. Epub 2024 Jan 30.ABSTRACTWe compared the clinical outcomes of second breast conserving therapy (2ndBCT) versus salvage mastectomy (sMT) for the treatment of ipsilateral breast tumour recurrences (IBTR). 195 patients who presented with an IBTR after previous breast conserving treatment were salvaged either with re-excision and perioperative interstitial brachytherapy (n=39) or sMT (n=156). A total dose of 5×4.4Gy was delivered to the tumour bed, on 3 consecutive days. The median follow-up time was 59 and 56 months. During follow-up 4 (10.2%) and 28 (17.9%) second local recurrences occur...
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Viktor Smanyk ó Source Type: research
Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy
This study aims to establish fast DL-based predictive dose algorithms for LDR (low-dose rate) prostate brachytherapy and to evaluate their uncertainty and stability.

Approach: Data from 200 prostate patients, treated with125I sources, was collected. The Monte Carlo (MC) ground truth dose volumes were calculated with TOPAS considering the interseed effects and an organ-based material assignment. Two 3D convolutional neural networks, UNet and ResUNet TSE, were trained using the patient geometry and the seed positions as the input. The dataset was randomly split into training (150), validation (25) and test (...
Source: Physics in Medicine and Biology - March 14, 2024 Category: Physics Authors: Francisco Berumen Samuel Ouellet Shirin A Enger Luc Beaulieu Source Type: research
Local treatment of ipsilateral breast cancer recurrences: comparison of alternative therapeutic options
Magy Onkol. 2024 Mar 14;68(1):86-88. Epub 2024 Jan 30.ABSTRACTWe compared the clinical outcomes of second breast conserving therapy (2ndBCT) versus salvage mastectomy (sMT) for the treatment of ipsilateral breast tumour recurrences (IBTR). 195 patients who presented with an IBTR after previous breast conserving treatment were salvaged either with re-excision and perioperative interstitial brachytherapy (n=39) or sMT (n=156). A total dose of 5×4.4Gy was delivered to the tumour bed, on 3 consecutive days. The median follow-up time was 59 and 56 months. During follow-up 4 (10.2%) and 28 (17.9%) second local recurrences occur...
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Viktor Smanyk ó Source Type: research
Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy
This study aims to establish fast DL-based predictive dose algorithms for LDR (low-dose rate) prostate brachytherapy and to evaluate their uncertainty and stability.

Approach: Data from 200 prostate patients, treated with125I sources, was collected. The Monte Carlo (MC) ground truth dose volumes were calculated with TOPAS considering the interseed effects and an organ-based material assignment. Two 3D convolutional neural networks, UNet and ResUNet TSE, were trained using the patient geometry and the seed positions as the input. The dataset was randomly split into training (150), validation (25) and test (...
Source: Physics in Medicine and Biology - March 14, 2024 Category: Physics Authors: Francisco Berumen Samuel Ouellet Shirin A Enger Luc Beaulieu Source Type: research
Local treatment of ipsilateral breast cancer recurrences: comparison of alternative therapeutic options
Magy Onkol. 2024 Mar 14;68(1):86-88. Epub 2024 Jan 30.ABSTRACTWe compared the clinical outcomes of second breast conserving therapy (2ndBCT) versus salvage mastectomy (sMT) for the treatment of ipsilateral breast tumour recurrences (IBTR). 195 patients who presented with an IBTR after previous breast conserving treatment were salvaged either with re-excision and perioperative interstitial brachytherapy (n=39) or sMT (n=156). A total dose of 5×4.4Gy was delivered to the tumour bed, on 3 consecutive days. The median follow-up time was 59 and 56 months. During follow-up 4 (10.2%) and 28 (17.9%) second local recurrences occur...
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Viktor Smanyk ó Source Type: research
Local treatment of ipsilateral breast cancer recurrences: comparison of alternative therapeutic options
Magy Onkol. 2024 Mar 14;68(1):86-88. Epub 2024 Jan 30.ABSTRACTWe compared the clinical outcomes of second breast conserving therapy (2ndBCT) versus salvage mastectomy (sMT) for the treatment of ipsilateral breast tumour recurrences (IBTR). 195 patients who presented with an IBTR after previous breast conserving treatment were salvaged either with re-excision and perioperative interstitial brachytherapy (n=39) or sMT (n=156). A total dose of 5×4.4Gy was delivered to the tumour bed, on 3 consecutive days. The median follow-up time was 59 and 56 months. During follow-up 4 (10.2%) and 28 (17.9%) second local recurrences occur...
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Viktor Smanyk ó Source Type: research
