Monte Carlo simulation study of an in vivo four-dimensional tracking system with a diverging collimator for monitoring radiation source (Ir-192) location during brachytherapy: proof of concept and feasibility
Discussion: These results indicated that the newly designed in vivo 4D tracking system for monitoring the Ir-192 source during brachytherapy could determine the 3D position of the radiation source in real time during treatment. We conclude that the proposed positioning system has the potential to make brachytherapy more accurate and reliable. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 25, 2024 Category: Physiology Source Type: research
Selective Internal Radiation Therapy Using Y-90 Resin Microspheres for Metastatic Colorectal Cancer: An Updated Systematic Review and Network Meta-Analysis
ConclusionCurrent evidence supports SIRT treatment in patients with chemotherapy-refractory or chemotherapy-intolerant mCRC compared to newer oral agents, with comparable OS and low incidence of AEs. (Source: Advances in Therapy)
Source: Advances in Therapy - March 24, 2024 Category: Drugs & Pharmacology Source Type: research
Rapid separation, purification of 90Sr and feasibility studies for the preparation of 90Y resin microsphere brachytherapy source from FBTR irradiated fuel dissolver solution
AbstractPresently several beta emitting radionuclides are in use as brachytherapy sources, due to their inherent advantages of short-range radiation dose delivery compared to their gamma emitting counterparts.90Y is one of the well-known hard beta-emitting radioisotopes for the therapeutic application of radioactivity. Among various other modalities,90Y resin microsphere as a brachytherapy source has its application for liver cancer. In the present study,90Y was recovered from235,238U,239Pu(nfast,f)90Sr( β−)90Y using Sr selective crown ether followed by quick purification using the Ion Chromatography technique. The puri...
Source: Journal of Radioanalytical and Nuclear Chemistry - March 23, 2024 Category: Nuclear Medicine Source Type: research
Hypofractionated whole breast IMRT with HDR brachytherapy boost in early-stage breast cancer: Long-term results from a single-center
The addition of a boost to the lumpectomy bed after whole-breast (WB) radiotherapy plays a key role in the treatment of patients with breast cancer (BC). The clinical benefits of a boost with high-dose-rate brachytherapy (HDR-BT) after conventional fractionation is supported by a large body of evidence. However, few studies have described its outcomes after a hypofractionated scheme. (Source: Brachytherapy)
Source: Brachytherapy - March 23, 2024 Category: Cancer & Oncology Authors: Ana Aurora D íaz-Gavela, Elia del Cerro Peñalver, Sofía Sanchez-Garcia, Eduardo Pardo-Perez, Israel John Thuissard-Vasallo, Cristina Andreu-Vázquez, María Yolanda Molina López, Marina Pena Huertas, Luis Leonardo Guerrero-Gómez, David Sanz-Rosa, Fel Tags: Original Research Source Type: research
A randomized trial evaluating a novel hydrogel packing system compared to standard packing during image-guided high-dose rate brachytherapy boost for cervical cancer
The purpose of this prospective randomized trial was to compare the use of a novel vaginal hydrogel packing system (BrachyGel) to standard vaginal packing (VP) during high dose rate (HDR) brachytherapy (BT) for locally advanced cervical cancer (LACC). (Source: Brachytherapy)
Source: Brachytherapy - March 21, 2024 Category: Cancer & Oncology Authors: Kara D. Romano, Gina Petroni, Kristi Ward, Wendy Zheng, Matthew Mistro, Bruce Libby, Christopher McLaughlin, Timothy N. Showalter, Einsley M. Janowski Tags: Original Article Source Type: research
Can an in-person hands-on applicator-based teaching session improve trainee knowledge and comfort with complex gynecologic brachytherapy?
With the emergence of imaged-based planning and hybrid applicators the complexity of gynecologic brachytherapy has dramatically increased. Despite the known advantages of brachytherapy, notable national declines in utilization of brachytherapy have been documented. Clearly improved education in the sphere of gynecologic brachytherapy is needed. We hypothesize that a hands-on applicator-based training session would improve trainee comfort with gynecologic brachytherapy. (Source: Brachytherapy)
Source: Brachytherapy - March 21, 2024 Category: Cancer & Oncology Authors: Abigail Groszkiewicz, Emily Foust, Brett Palestra, Michelle C. Ertel, Michelle Boisen, Paniti Sukumvanich, Shannon Kroskie Smith, Ryan P. Smith, John A. Vargo Source Type: research
Corrigendum to “BLEEDERS IN CHECK: A Duke RadOnc Approach to Limiting Interruptions in GYN HDR Brachytherapy Treatments” [Brachytherapy September-October 2023; 22(5 Suppl):S90]
The authors regret that there was an error in our author block. We missed to provide the new married name of one of our authors, Amber Byrd. Some professional titles were also omitted. Author details were missed during our proofreading. Otherwise, there is no correction to abstract content. (Source: Brachytherapy)
Source: Brachytherapy - March 21, 2024 Category: Cancer & Oncology Authors: Rustica Blasco Cerillo, Amber W. Byrd, Mary Ann Monson, Lisa Thigpen, Kimberly DeBaun Tags: Corrigendum Source Type: research
21 Gy single fraction prostate HDR brachytherapy: 5-year results of a single institution prospective pilot study
To present the outcome and toxicity results of a prospective trial of 21 Gy single fraction high-dose-rate (HDR) brachytherapy for men with low- or intermediate-risk prostate cancer. (Source: Brachytherapy)
Source: Brachytherapy - March 20, 2024 Category: Cancer & Oncology Authors: Kamran Salari, Allison J. Hazy, Hong Ye, Evelyn Sebastian, Amy Limbacher, Matthew Johnson, Beth Mitchell, Andrew B. Thompson, Zachary A. Seymour, Sirisha R. Nandalur, Daniel J. Krauss Source Type: research
Genitourinary toxicity in patients receiving TURP prior to hypofractionated radiotherapy for clinically localized prostate cancer: A scoping review
CONCLUSION: For those who have undergone prior TURP hypofractionated radiotherapy may increase the risk of late urinary toxicity, particularly hematuria. Those with persisting bladder dysfunction following TURP are at greatest risk and careful management of these men is required. Close collaboration between urologists and radiation oncologists is recommended to discuss the management of patients with residual baseline bladder dysfunction prior to commencing hypofractionated radiotherapy.PMID:38503591 | DOI:10.1016/j.urolonc.2024.02.011 (Source: Urologic Oncology)
Source: Urologic Oncology - March 19, 2024 Category: Urology & Nephrology Authors: Thomas Neerhut Richard Grills Rod Lynch Patrick Daniel Preece Kathryn McLeod Source Type: research
Interstitial needles versus intracavitary applicators only for locally advanced cervical cancer: results from real-life dosimetric comparisons
ConclusionHR-CTV coverage was higher with IC/IS IGABT than with IC IGABT, with lower doses to the OAR in patients managed for LACC after RCT. Interstitial brachytherapy in the management of LACC after radiotherapy provides better coverage of the target volumes, this could contribute to better local control and improved survival of patients. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 19, 2024 Category: Cancer & Oncology Source Type: research
A Randomized Trial Comparing Quality of Life After LDR or HDR Prostate Brachytherapy Boost with Pelvic External Beam Radiation Therapy
CONCLUSIONS: Patient experience for combined EBRT and prostate BT is improved with HDR BT. Urinary QoL improves over time to be equivalent between the 2 modalities after 18 months, but LDR patients report lasting bowel symptoms.PMID:38493901 | DOI:10.1016/j.ijrobp.2024.02.064 (Source: Health Physics)
Source: Health Physics - March 17, 2024 Category: Physics Authors: Juanita Crook Nikitha Moideen Greg Arbour Felipe Castro C ánovas Cynthia Araujo Deidre Batchelar Ross Halperin Michelle Hilts David Kim David Petrik Jim Rose J C Cheng Francois Bachand Source Type: research
