Detailed statistical analysis plan for the short-term versus long-term mentalisation-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder randomised clinical trial (MBT-RCT)
DiscussionWe have developed this statistical analysis plan before unblinding of the trial results in line with the Declaration of Helsinki and the International Conference on Harmonization of Good Clinical Practice Guidelines, which should increase the validity of the MBT-RCT trial by mitigation of analysis bias.Trial registrationClinicalTrials.govNCT03677037. Registered on 19 September 2018 (Source: Trials)
Source: Trials - July 28, 2021 Category: Research Source Type: clinical trials

Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
Condition:   Borderline Personality Disorder Intervention:   Other: Evaluation using the Self-Defining Memory Questionnaire Sponsor:   Centre Hospitalier Universitaire de NÄ«mes Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 2, 2021 Category: Research Source Type: clinical trials

Study to Test the Efficacy and Safety of Vafidemstat in Adult Borderline Personality Disorder Population
Condition:   Borderline Personality Disorder Interventions:   Drug: vafidemstat;   Drug: Placebo Sponsor:   Oryzon Genomics S.A. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 21, 2021 Category: Research Source Type: clinical trials

Assessing the efficacy of a stepped-care group treatment programme for borderline personality disorder: study protocol for a pragmatic trial
AbstractBackgroundBorderline personality disorder (BPD) is a high prevalence and serious mental health disorder that has historically challenged the finite resources of health services. Despite empirical evidence supporting structured psychological therapy as the first line of treatment, there remains significant barriers in providing timely access to evidence-based treatment for this population. The primary aim of this study is to evaluate the effectiveness of providing a stepped-care structured psychological group treatment to individuals with BPD within local mental health services. The secondary aims of the study are t...
Source: Trials - June 7, 2021 Category: Research Source Type: clinical trials

Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS
Conditions:   Depressive Disorder, Major;   Borderline Personality Disorder Interventions:   Device: Left Dorsolateral Prefrontal Cortex (L-DLPFC);   Device: Dorsomedial Prefrontal Cortex (DMPFC);   Device: Sham Stimulation Sponsor:   Stanford University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 3, 2021 Category: Research Source Type: clinical trials

Neuroimaging of adolescent borderline personality disorder with and without post-traumatic stress disorder
Condition:   Borderline Personality Disorder Intervention:   Other: Brain MRI Sponsors:   University Hospital, Caen;   CHU de Rouen - Accueil;   Centre Hospitalier Universitaire de Caen;   Université de Caen Normandie;   Centre Hospitalier du Rouvray;   Institut National de la Santé Et de la Recherche Médicale, France;   Groupe Hospitalier du Havre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 21, 2021 Category: Research Source Type: clinical trials

Effectiveness of a Short and Telematic Version of Cognitive-behavioral Treatment for Borderline Personality Disorder
Condition:   Borderline Personality Disorder Interventions:   Behavioral: Dialectical Behavior Therapy -3-months;   Behavioral: Dialectical Behavior Therapy -6-months Sponsors:   Pontificia Universidad Catolica de Chile;   University Diego Portales Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2021 Category: Research Source Type: clinical trials