Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Clinical course and molecular characterization of human Bocavirus associated with acute lower respiratory tract infections in tertiary care hospital of north India
Jpn J Infect Dis. 2024 Feb 29. doi: 10.7883/yoken.JJID.2023.251. Online ahead of print.ABSTRACTRespiratory samples from 139 hospitalized children were screened for the Human Bocavirus (HBoV) genome. Positive samples were sequenced for partial VP1/VP2 gene followed by molecular and phylogenetic analyses. HBoV positivity was noted in 7.2% (10/139) patients. All HBoV positive children presented with fever followed by cough and respiratory distress (90%; 9/10). Three children developed multisystemic viral illness with one fatality. Eight children required intensive care management and mechanical ventilation required for 5 chil...
Source: Japanese Journal of Infectious Diseases - February 28, 2024 Category: Infectious Diseases Authors: Subhabrata Sarkar Mannat Kang Suresh Kumar Angurana Shankar Prasad Ishani Bora Pankaj Singh Vikrant Sharma Meenakshi Rana Bhartendu Singh Jayashree Muralidharan Radha Kanta Ratho Source Type: research
Management Strategies for Pediatric Cases of Severe Plastic Bronchitis: Addressing Acute Respiratory Failure in the Context of Human Bocavirus Infection
This report aims to document the rescue and nursing experience in managing a pediatric patient presenting with severe plastic bronchitis accompanied by acute respiratory failure attributed to human bocavirus infection. Emergency bronchoscopy surgery was promptly and effectively performed to address the immediate medical needs. Subsequently, rigorous monitoring of pulmonary signs and optimized airway management were implemented to strengthen postoperative care. Proactive measures were taken to address airway reobstruction and hypercapnia promptly while maintaining active control over infections. (Source: The Journal for Nurse Practitioners)
Source: The Journal for Nurse Practitioners - February 8, 2024 Category: Nursing Authors: Wangfang Xie, Jihua Zhu, Xiaofang Lou, Bin Xu Tags: Case Report Source Type: research
Asymptomatic viruses detectable in saliva in the first year of life: a narrative review
Pediatr Res. 2023 Dec 22. doi: 10.1038/s41390-023-02952-0. Online ahead of print.ABSTRACTViral infections are common in children. Many can be asymptomatic or have delayed health consequences. In view of increasing availability of point-of-care viral detection technologies, with possible application in newborn screening, this review aimed to (1) identify potentially asymptomatic viruses detectable in infants under one year old, via saliva/nasopharyngeal swab, and (2) describe associations between viruses and long-term health conditions. We systematically searched Embase(Ovid), Medline(Ovid) and PubMed, then further searched...
Source: Pediatric Research - December 22, 2023 Category: Pediatrics Authors: Melody Goh Charissa Joy Alanna N Gillespie Qi Rui Soh Fan He Valerie Sung Source Type: research
Asymptomatic viruses detectable in saliva in the first year of life: a narrative review
Pediatr Res. 2023 Dec 22. doi: 10.1038/s41390-023-02952-0. Online ahead of print.ABSTRACTViral infections are common in children. Many can be asymptomatic or have delayed health consequences. In view of increasing availability of point-of-care viral detection technologies, with possible application in newborn screening, this review aimed to (1) identify potentially asymptomatic viruses detectable in infants under one year old, via saliva/nasopharyngeal swab, and (2) describe associations between viruses and long-term health conditions. We systematically searched Embase(Ovid), Medline(Ovid) and PubMed, then further searched...
Source: Pediatric Research - December 22, 2023 Category: Pediatrics Authors: Melody Goh Charissa Joy Alanna N Gillespie Qi Rui Soh Fan He Valerie Sung Source Type: research
Asymptomatic viruses detectable in saliva in the first year of life: a narrative review
Pediatr Res. 2023 Dec 22. doi: 10.1038/s41390-023-02952-0. Online ahead of print.ABSTRACTViral infections are common in children. Many can be asymptomatic or have delayed health consequences. In view of increasing availability of point-of-care viral detection technologies, with possible application in newborn screening, this review aimed to (1) identify potentially asymptomatic viruses detectable in infants under one year old, via saliva/nasopharyngeal swab, and (2) describe associations between viruses and long-term health conditions. We systematically searched Embase(Ovid), Medline(Ovid) and PubMed, then further searched...
Source: Pediatric Research - December 22, 2023 Category: Pediatrics Authors: Melody Goh Charissa Joy Alanna N Gillespie Qi Rui Soh Fan He Valerie Sung Source Type: research
Use of Metagenomic Next-Generation Sequencing in the Identification of Pneumocystis Jiroveci Pneumonia in a Previously Healthy Infant Diagnosed With X-Linked Hyper-IgM Syndrome
This case describes a four-month-old male who was admitted to the pediatric intensive care unit for acute respiratory failure in the setting of a co-infection requiring increased ventilatory support. Immunodeficiency workup demonstrated poor vaccination response and low immunoglobulin titers. mNGS via Karius ® test was positive for Pneumocystis jiroveci (PJP), Parvovirus, and Bocavirus. The patient was successfully treated with trimethoprim-sulfamethoxazole and prednisone. Genetic workup via Invitae panel confirmed that the patient had X-linked Hyper-IgM Syndrome. (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - November 29, 2023 Category: Pediatrics Authors: Jocelyn Dennis, Courtney Massey, Teddy Muisyo, Gabriela Moraru, Manzilat Akande Tags: Specialty Case Report Source Type: research
