Viral metagenomics of pharyngeal secretions from children with acute respiratory diseases with unknown etiology revealed diverse viruses
This study investigated the potential reasons of unexplained acute respiratory infections in children in Xuzhou and its environs during 2018-2019.We collected pharyngeal swab samples from 411 children under the age of five who presented with symptoms of unexplained acute respiratory infection and were negative for bacteria, mycoplasma, and influenza viruses. Using viral metagenomic techniques, viral nucleic acids were extracted, enriched, and sequenced from the samples. Results indicated that Picornaviridae, Parvoviridae, Paramyxoviridae, Coronaviridae, and Anelloviridae were the five virus families with the highest relati...
Source: Virus Research - September 4, 2022 Category: Virology Authors: Qingqing Mao Guangming Sun Yu Qian Yuchen Qian Wang Li Xiaochun Wang Quan Shen Shixing Yang Chenglin Zhou Hao Wang Wen Zhang Source Type: research

Viral metagenomics of pharyngeal secretions from children with acute respiratory diseases with unknown etiology revealed diverse viruses
This study investigated the potential reasons of unexplained acute respiratory infections in children in Xuzhou and its environs during 2018-2019.We collected pharyngeal swab samples from 411 children under the age of five who presented with symptoms of unexplained acute respiratory infection and were negative for bacteria, mycoplasma, and influenza viruses. Using viral metagenomic techniques, viral nucleic acids were extracted, enriched, and sequenced from the samples. Results indicated that Picornaviridae, Parvoviridae, Paramyxoviridae, Coronaviridae, and Anelloviridae were the five virus families with the highest relati...
Source: Virus Research - September 4, 2022 Category: Virology Authors: Qingqing Mao Guangming Sun Yu Qian Yuchen Qian Wang Li Xiaochun Wang Quan Shen Shixing Yang Chenglin Zhou Hao Wang Wen Zhang Source Type: research

Respiratory syncytial virus among children hospitalized with severe acute respiratory infection in Kashmir, a temperate region in northern India
CONCLUSIONS: Respiratory viruses, especially RSV, contributed to a substantial proportion of SARI hospitalizations among children <5 years in north India. These data can help guide clinicians on appropriate treatment and prevention strategies.PMID:35976005 | DOI:10.7189/jogh.12.04050 (Source: Adv Data)
Source: Adv Data - August 17, 2022 Category: Epidemiology Authors: Parvaiz A Koul Siddhartha Saha Kaisar A Kaul Hyder Mir Varsha Potdar Mandeep Chadha Danielle Iuliano Kathryn E Lafond Renu B Lal Anand Krishnan Source Type: research

Respiratory syncytial virus among children hospitalized with severe acute respiratory infection in Kashmir, a temperate region in northern India
CONCLUSIONS: Respiratory viruses, especially RSV, contributed to a substantial proportion of SARI hospitalizations among children <5 years in north India. These data can help guide clinicians on appropriate treatment and prevention strategies.PMID:35976005 | DOI:10.7189/jogh.12.04050 (Source: Adv Data)
Source: Adv Data - August 17, 2022 Category: Epidemiology Authors: Parvaiz A Koul Siddhartha Saha Kaisar A Kaul Hyder Mir Varsha Potdar Mandeep Chadha Danielle Iuliano Kathryn E Lafond Renu B Lal Anand Krishnan Source Type: research

A study of the novel wu and ki polyomaviruses, bocavirus adenovirus in children with upper respiratory tract infections
Conclusions: High frequency of HBoV especially in immunocompromised patients while low number of positive cases for HAdv by using nasal swab samples, WU and KI polyomaviruses could not be detected in samples.PMID:35962680 | DOI:10.36740/WLek202207112 (Source: Cancer Control)
Source: Cancer Control - August 13, 2022 Category: Cancer & Oncology Authors: Husam Hussein Lazim Shatha Hussain Ali Ahmed Sahib Abdul-Amir Asmaa Baqir Salim Source Type: research

Epidemiologic and clinical characteristics of human bocavirus infection in children hospitalized for acute respiratory tract infection in Qingdao, China
Persistent infection and prolonged shedding of human bocavirus 1 (HBoV1) in children have been reported, and the role of HBoV1 as a sole causative pathogen in acute respiratory infection (ARI) is yet to be established. While the reported prevalence of HBoV infection varies due to different detection methods and sampling criteria, determining the viral and bacterial etiology of HBoV infection using multiplex real-time PCR is yet to be reported. Herein, we aimed to further explore the pathogenicity of HBoV in patients with ARI by screening the viral and bacterial infections in children with ARI in Qingdao and comparing the e...
Source: Frontiers in Microbiology - August 10, 2022 Category: Microbiology Source Type: research

Respiratory virus transmission using a novel viral challenge model: an observational cohort study
The recent emergence of Coronavirus Disease- 2019 (COVID-19), coupled with its morbidity and mortality, has renewed interest in how respiratory viruses are transmitted. Knowledge of the determinants of transmission is critical in informing non-pharmaceutical interventions and preventing spread. Whilst current concerns about infections due to SARS-CoV-2 predominate, other common causes of Acute Respiratory virus Infection (ARI) include rhinoviruses (RVs), enteroviruses (EV), respiratory syncytial viruses (RSV-A and RSV-B), influenza A and B (Flu), coronaviruses (CoV), adenoviruses (AdV), parainfluenza viruses (PIV), human m...
Source: Journal of Infection - August 6, 2022 Category: Infectious Diseases Authors: Marie-jo Medina, Joshua Nazareth, Helen M. Dillon, Christopher J. Wighton, Srini Bandi, Daniel Pan, Karl G. Nicholson, Tristan W. Clark, Peter W. Andrew, Manish Pareek Source Type: research

Human bocavirus 1 is a genuine pathogen for acute respiratory tract infection in pediatric patients determined by nucleic acid, antigen, and serology tests
ConclusionsThe combination results of nucleic acid, antigen, and serology tests answered that HBoV1 is a genuine pathogen for ARTI in pediatric patients. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - July 29, 2022 Category: Microbiology Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research

Is there a role of viral infection in cystic fibrosis exacerbation in children?
CONCLUSIONS: This study demonstrated that exacerbation in cystic fibrosis may be exaggerated by viral infections such as influenza A and enterovirus necessitating hospitalization which shows the important protective role of vaccination. Also, a strong relationship was detected between some viruses such as enterovirus, human metapneumovirus and influenza and between bacterial infection.PMID:35899568 | DOI:10.24953/turkjped.2020.1926 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - July 28, 2022 Category: Pediatrics Authors: Dina H Hamed Mai Sherif Soliman Ola Soliman Emam Mona Mohsen El-Attar Source Type: research