Evolution of the Microbiome – Comparing the Ancestral and Modern Microbiome
We now understand that it’s not just a question of living in a rural versus a urban environment, but we have actually changed our gut bacteria in going from ancient times to more modern times. We now have the tools at our disposal to be able to look at the makeup of the microbiome based on analysis of fossilized stool samples. In a recent study the stool of humans from thousands of years ago was analyzed and it was determined that the microbiomes of our rural ancestors more closely resembles that of modern rural humans as opposed to urban dwellers. The post Evolution of the Microbiome – Comparing the Ancestral ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 1, 2015 Category: Neurologists Authors: gbadmin Tags: Brain Maker Science Videos microbiome Source Type: blogs

Gut Bacteria & BDNF
The post Gut Bacteria & BDNF appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 30, 2015 Category: Neurologists Authors: gbadmin Tags: Brain Maker Exercise Nutrition Science Videos Source Type: blogs

Gwen F.
I was diagnosed with high cholesterol a couple of years ago, and was put on a statin drug. While I was on it, I was fatigued and “draggy” all the time…I even woke up fatigued!  Anyway, after hearing about the side effects of statins last year, I quit taking it. I changed my diet to vegan, hoping to become healthier and lose some weight. I lost 3 or 4 pounds and that was it. After several months of eating vegan, I had to have my cholesterol and triglyceride levels checked for my health insurance.  Imagine my shock when I was told that my triglyceride level was over 300, and my total cholesterol was 200! ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success Fatigue weight loss Source Type: blogs

Leslie T.
I was at a crossroads in my health situation. At 55 years old, I was still able to perform my daily tasks, including caregiving for a head injured foster son who is large. At night though, I could not sleep due to acid reflux, night sweats, anxiety, joint pain, and just general discomfort. I was cranky and angry because of my insulin resistance. My mood swings had my family in discord. In 1989, I had a surgery on an artery in my leg. Doctors told me then that I had an autoimmune disease that affected my tissues. This disease would sometimes flare up and cause extreme bruising. I was foggy minded and my nose ran all the ti...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success Fatigue weight loss Source Type: blogs

Linda T.
I am 52 years old and am currently taking Cymbalta, 30mg for depression. I have been seriously depressed for too long along with severe anxiety. Only one month after becoming gluten free, and reducing my carbohydrate and sugar intake, I am a totally different person. Honestly, it is like night and day. My anxiety has disappeared; I am calm.  I’m not depressed. Instead, I’m feeling good and content. I used to think that I would be on antidepressants forever, but now I feel like there’s hope that one day I won’t need them anymore. -Linda T. The post Linda T. appeared first on David Perlmutter M.D.. (Source: R...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success Anxiety Depression Source Type: blogs

Janet M.
I began suffering from depression in my mid 20s. This condition affected the path of my life as I was unable to function for months at a time. I was on antidepressants all through my 30s, trying cocktail after cocktail only to suffer terribly from side effects. Towards the end of my 30s I developed a gluten intolerance and tried to avoid gluten (with only moderate success!). I was completely addicted to sugar, gluten and carbs. I was also horribly addicted to sugar. My point is, my carb, gluten and sugar addiction was a long struggle. I read Grain Brain at the beginning of January 2015 and immediately implemented a low...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success Fatigue Source Type: blogs

Shabd S.
Here in Alaska we watch grizzly bears chow down on blueberries like nobody’s business each fall. I used to wonder how berries could help bears put on fat, as I had thought you needed fat to put on fat! Then the pieces came together! I often forget why I walked into a room, and I experience a triggered memory begin to follow a synaptic path at times to have it disappear into a nebulous nothing. I am not considered overweight, but could feel visceral fat inside after menopause. Now, I am very happy to include plenty of fat in my diet and in even just 5 days, the extra body fat is melting off and I am understanding my ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success Gluten Sensitivity weight loss Source Type: blogs

Deanna S.
After turning 50 I started “falling apart.” I had already been diagnosed with hypothyroidism, and my memory was failing me, even though it had always been sharp. Arthritis and carpal tunnel syndrome were increasing and causing me a lot of joint pain. The worst health issue I was experiencing was allergies to everything! Skin sensitivity and eczema had always plagued me, but now my arms would get a pimple or bump and itch like crazy. Gas, bloating and indigestion seemed normal to me. Last October, after eating one of my favorite meals—deep-dish pizza—I cramped up so bad I couldn’t sleep. A visit to ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success hypothyroidism Joint Pain weight loss Source Type: blogs

Edd M.
Since reading Grain Brain I have lost 16kgs, gained lean mass, started resistance and conditioning training, and generally had a “lifestyle change” for the better. I found that with previous diets, such as Atkins, I mistakenly ate too much protein and not enough fat, nor was I incorporating exercise. After initially losing a lot of weight, most of it would be put back on once the diet had “finished.” Now I realize that eating and exercise habits need to change if the weight is to stay off for the long-term. Going low-carb for me actually meant I had more energy than before, therefore doing exercise was le...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 28, 2015 Category: Neurologists Authors: gbadmin Tags: Success weight loss Source Type: blogs

Hygiene Hypothesis
The post Hygiene Hypothesis appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - January 27, 2015 Category: Neurologists Authors: gbadmin Tags: Brain Maker Science Videos Source Type: blogs

Manchego Tortilla – The Grain Brain Cookbook
One of the 150+ recipes in The Grain Brain Cookbook. Find the recipe here on my site. The post Manchego Tortilla – The Grain Brain Cookbook appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 29, 2014 Category: Neurologists Authors: gbadmin Tags: Recipes Videos Source Type: blogs

Drink for Your Health
No doubt, if you’ve been following my blog, or reading Grain Brain, you’ve certainly gotten the message that you’ve got to do everything you can to avoid consumption of sugar. Scientific research has certainly made it clear that sugar consumption strongly relates to such maladies as coronary artery disease, obesity, and type 2 diabetes. Unfortunately, this aggressive castigation of sugar consumption has led to an increase in people choosing to drink “sugar-free” beverages with the misguided sense that this represents a healthy alternative. The reality of the situation is that nothing could be further from the tru...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 28, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Science diabetes diet soda obesity sugar sugar-free Source Type: blogs

Dan E.
My wife Kate had long been suffering with, what I referred to as, an irritable bowel condition for quite some time. Her gastroenterologist after a colon exam, told her to eat a lot of “Bran Buds” every day and consume a daily fiber drink, along with a laxative. Upon following this advice, her condition deteriorated. She entered into phases of severe pain and sleeplessness, leading to extreme fatigue. We knew this wasn’t working and needed to try something different. After a few days on gluten-free, low-carb diet, her symptoms disappeared completely! Not only that, but her GP has previously put her on Crestor, ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 28, 2014 Category: Neurologists Authors: gbadmin Tags: Success Fatigue IBD IBS Source Type: blogs

Patricia C.
In Grain Brain, I found a book that had resonated with what I had for so long believed to be the truth about optimal health. Prior to reading, I had suffered from severe headaches since I was eleven. Once I stopped eating gluten, lowered my carb intake, and increased my fat intake, my condition suddenly began to improve! Now, I rarely get headaches, and if I do they go away quickly. I also lost weight and my overall mood has improved. I’m very happy with my results! -Patricia C. The post Patricia C. appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 28, 2014 Category: Neurologists Authors: gbadmin Tags: Success Headache Migraine weight loss Source Type: blogs

The Vitamin That May Save Your Brain
We’ve certainly learned a lot more about the health benefits of vitamin D over the past decade. While it’s long been recognized that vitamin D is important for strong and healthy bones, it’s role in health and longevity is now recognized as casting a very wide net. Over the past several years, vitamin D deficiency has been associated with increased risk for such brain-related disorders as Parkinson’s disease, multiple sclerosis, autism, and even dementia. With reference to the latter, a new study published in the journal Neurology, correlated low levels of vitamin D to increased risk of developing dementia to a fa...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 25, 2014 Category: Neurologists Authors: gbadmin Tags: Science Supplements Alzheimer’s Autism Dementia MS Parkinson's Vitamin D Source Type: blogs

Don’t miss this delicious salmon recipe from The Grain Brain Cookbook
Enjoy this recipe for Salmon with Mustard Glaze. It’s a delicious choice for lunch or dinner. This is the first of three cooking videos I will be sharing based on recipes that can be found in The Grain Brain Cookbook. The post Don’t miss this delicious salmon recipe from The Grain Brain Cookbook appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 24, 2014 Category: Neurologists Authors: gbadmin Tags: Videos grain brain cookbook salmon Source Type: blogs

ALS Ice Bucket Challenge
Here’s my take on the ALS Ice Bucket Challenge.  To learn more about ALS, view one of my previous blog posts on the subject. The post ALS Ice Bucket Challenge appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 21, 2014 Category: Neurologists Authors: gbadmin Tags: Videos ALS Source Type: blogs

CoQ10: Powerful Supplement for Health
Discussion of the Evidence, Scope, Benefits and Risk. Please take a look at this discussion as I’m certain it will help answer some important questions. In addition, some very informative research about coenzyme Q10 can be found in the science section of our website. Coenzyme Q10 is one of the most fundamentally important nutritional supplements I recommend and use in my clinical practice not just for patients with heart disease, but to support brain health and general health as well. We generally recommend 100mg daily, and 200mg daily for those on statins, beta-blockers, or tricyclic antidepressants. The post CoQ10: Pow...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 19, 2014 Category: Neurologists Authors: gbadmin Tags: Science Supplements beta-blockers blood pressure Cardiovascular disease Cholesterol CoQ10 heart lipitor migraines Statins toprol zocor Source Type: blogs

But… it’s Gluten Free?
I frequently hear from patients and friends that they are surprised they aren’t losing weight even though they’ve “gone gluten-free.” It’s at that point that I ask for a little bit of clarification in terms of what they think being gluten-free really means. I often learn, surprisingly, that people often say that they only shop from the gluten-free aisle in the grocery store as if that’s some kind of feather in their cap. Many grocery stores do in fact have gluten-free sections. And what is so disenchanting is the realization that what they are selling includes gluten-free pastas, cakes, cookies, breads, etc. th...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 17, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Videos blood sugar Gluten gluten free high-carb Source Type: blogs

4 Reasons Why Kale is a True Superfood
By: Austin Perlmutter, Medical Student, Miller School of Medicine When it comes to healthy vegetables, kale may be among the best. Packing a powerful punch of antioxidants, nutrients and excellent digestive support, its role in optimal wellness is tough to dispute. For anyone still undecided, here are the top 4 reasons to make kale a part of your life. Kale is jam-packed with vitamins. Eating one cup of chopped kale gets you over 200% of your daily value of vitamin A, 134% of your daily value for vitamin C, and almost 700% of your daily value for vitamin K! In addition, kale contains important minerals like manganese, p...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - August 14, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition antioxidants fiber kale Omega-3 Pesto vitamin a vitamin c vitamin k Source Type: blogs

Inflammation – Strong Relationship to Dementia
Inflammation is a process with which we are all familiar. Whether from an insect bite or an arthritic joint, we associate inflammation with the typical observations of pain, redness, and swelling as well as loss of function. In Grain Brain as well as my recent PBS program, BrainChange, I described that this very same process, inflammation, is actually a pivotal player in such diverse brain conditions as Alzheimer’s disease, multiple sclerosis, Parkinson’s disease and even autism. That said, the most fundamental take home message of all my media outreach is to convince everyone willing to listen that you’ve got to do ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 26, 2014 Category: Neurologists Authors: gbadmin Tags: Science Alzheimer’s Arthritis Autism blood sugar Brainchange glycation Grain Brain inflammation multiple sclerosis pain Parkinson's Source Type: blogs

Laura M.
Seven years ago I had a grand mal seizure and it was discovered I had a brain tumor (astrocytoma grade 3). It was so large that my entire right parietal lobe had to be removed in order to get the whole tumor. One year later I suddenly developed what was diagnosed as reactive hypoglycemia. I was told I had to eat every two hours and, in fact, if I didn’t I got the shakes very quickly. I was having to eat so often that I no longer enjoyed eating. I saw you on my local PBS station, bought the book and haven’t turned back since. I can go for 5 hours without eating and now I can actually be hungry and eat. In fact, ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 25, 2014 Category: Neurologists Authors: gbadmin Tags: Success brain tumor grand mal grand mal seizure hypoglycemia Source Type: blogs

Mike and Linda G.
What a wonderful story of success from Mike and Linda. It’s great to see how they go through this together. – Dr. Perlmutter My wife bought your book “Grain Brain” a few months ago and like most books we buy, it just sat on the coffee table for a while and neither of us even opened it for a few days.  When Linda first picked up the book and began to read, it became obvious that this was not just another diet book that was going to fail us again. We both have strong histories of Alzheimer’s disease and dementia in our families and, from first-hand experience, it is the most cruel and debilitating disease ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 25, 2014 Category: Neurologists Authors: gbadmin Tags: Success Alzheimer's disease Dementia energy knee replacement Sleep spinal fusion weight loss Source Type: blogs

Gluten and the Microbiome
In humans, the relationship between type 1 diabetes and celiac disease is clear: having celiac disease dramatically increases risk for becoming a type 1 diabetic. But even beyond those with celiac disease, it has now been shown that early introduction of gluten-containing cereals in infancy is directly related to increased risk for type 1 diabetes. The why and how of this relationship are still not perfectly clear. However, new research is focused on the role of dietary gluten in challenging the microbiome – the 100 trillion bacteria living within each of us – and how this paves the way for increased inflammation and a...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 25, 2014 Category: Neurologists Authors: gbadmin Tags: Science autoimmunity bacteria diabetes Gluten inflammation intestines mice microbiome Type 1 Diabetes Source Type: blogs

Pesticides Increase Risk for Neurodegenerative Conditions
We vote with our wallets. That said, we are certainly seeing a substantial increase in interest in organic foods, and with good reason. It has become clear that aside from the nutritional advantages of organic food choices, there is indeed valid concern with reference to the toxic effects of residual pesticides in fruits and vegetables. From my perspective as a neurologist I want to consider all possibilities when it comes to factors that may increase a person’s risk for such maladies as Parkinson’s and Alzheimer’s. New research clearly links pesticides and other toxic exposures to increasing risk for these condition...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 24, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Science Alzheimer’s neurologist Parkinson's pesticides Source Type: blogs

Getting the Answers
Last month, you may have seen a post on my Facebook page about an interview I had done with Medscape. A few weeks later, the interview was made available to the general public on WebMD. The main focus of the interview was to allow me to explain how and why gluten and carbohydrates represent such a powerful threat to the human brain. Now that the article has had a chance to disseminate across the internet, I’ve seen a flood of comments from medical practitioners, industry experts, and interested individuals, asking questions, providing anecdotal evidence, offering support, and much, much more. So, I wanted to take an oppo...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 21, 2014 Category: Neurologists Authors: gbadmin Tags: Grain Brain Nutrition Science athletes calories carbs cereal Diet exercise fat fruit Grains medscape Paleo protein sugar webmd white bread Source Type: blogs

Christine T.
I love to hear from fellow medical professionals like Christine, who have shifted their way of thinking based on their personal experience with a changed diet/lifestyle. – Dr. Perlmutter I have battled my weight all my life. In my early 20′s, an allergist warned me that I was sensitive to many grains and that I should eat them sparingly. I ignored it. At 49 I was diagnosed with Type 2 diabetes. I continued eating my usual diet and my blood sugars continued to rise, as did my insulin doses. When I was told I needed four injections a day as well as oral medications, I had just about had it. I was overweight sign...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 19, 2014 Category: Neurologists Authors: gbadmin Tags: Success blood sugar Carbohydrates carbs diabetes ebergy insulin nausea protein restless leg syndrome RLS Sleep Type 2 diabetes weight loss Source Type: blogs

Cindy J.
The success Cindy has seen with her migraines has been well-documented in others. There are some studies available on my site that highlight this. – Dr. Perlmutter I have suffered from migraines for 26 years. They have been debilitating and over the years I have tried everything to prevent them. My neurologist has prescribed an arsenal of drugs, including beta-blockers, anti-depressants, calcium channel blockers, antihistamines and topamax. I tried eliminating triggers from my diet to no avail. I always got a migraine when the pressure dropped and there was a storm. Nothing stopped my weekly headaches. Sometimes I...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 19, 2014 Category: Neurologists Authors: gbadmin Tags: Success avocado carbs coconut oil gluten free Headaches Migraine protein Shake Source Type: blogs

Ruth Ann N.
I’m an RN. I ordered Grain Brain after seeing you on FOX & Friends. My husband had ignored my suggestions that he lose weight for years. The last week of November and first week of December 2013 he was going to have cataract surgery. I suggested he try the low-carb, gluten-free diet because his blood sugar a year before had been pre-diabetic. He was concerned about the chance of infection and loss of sight so he agreed. During the week before Thanksgiving and the week after, he lost 10 pounds! His 2-hour post-prandial blood sugar was 98. To date, he has gone from 215 pounds a week before Thanksgiving to 192.9 po...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 14, 2014 Category: Neurologists Authors: gbadmin Tags: Success cataract Cyrex psoriasis Supplements turmeric Vitamin D weight loss Source Type: blogs

Mark B.
It’s great to hear that the changes Mark has made to his diet and lifestyle have allowed him to do his favorite things once again. – Dr. Perlmutter Three years ago my weight was up to 165 lbs. (I am 5-7 tall, was 62 at the time). One day, my wife wife just looked at me and said, “Enough!” We went on the HCG diet that a coworker had lost about 30 lbs. on. I lost about 8 lbs. and noticed that my joints were no longer aching. This had been a common affliction all my adult life. I had always attributed it to a severe penicillin reaction when I was 7. But, when I began to eat my favorite foods again and ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 14, 2014 Category: Neurologists Authors: gbadmin Tags: Success aches anemia gluten free joints pains weight loss Source Type: blogs

Reverse Aging with Resveratrol
It’s true that if you lead a Grain Brain-friendly lifestyle, you can’t crack open a cold beer (even the gluten-free kind). However, that doesn’t mean all alcohol is off-limits. In fact, you can, and I do, enjoy the occasional glass of red wine. The reason for this? Not just because it tastes great and pairs well with all that grass-fed beef you’ll be eating, but because it’s an incredibly rich source of resveratrol, a natural compound found in grapes. Resveratrol has delivered a reputation for being able to deliver a whole host of benefits to our body, ranging from promoting heart health to boosting blood flow to...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 11, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Supplements grapes red wine Resveratrol Source Type: blogs

Jackie U.
Three weeks ago, a friend of mine, who has IBS, told me to eliminate flour and sugar after I told her about my symptoms of painful, achy feet, ankles and knees. In addition, I was experiencing migraines every other day, regular fatigue, and persistent brain fog! Three weeks in, after cutting gluten and sugar from my diet, I exhibit none of those symptoms at all! I have only had two headaches in the past three weeks and my energy levels are at an all-time high! -Jackie U. The post Jackie U. appeared first on David Perlmutter M.D.. (Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN)
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 10, 2014 Category: Neurologists Authors: gbadmin Tags: Success brain fog Fatigue Gluten Headache IBS Migraine sugaar Source Type: blogs

Why We Shouldn’t Focus on Developing Alzheimer’s Treatments
Recently, The New York Times announced the creation of a partnership between the National Institutes of Health, 10 pharmaceutical companies and seven nonprofit organizations dedicated to the development of drugs to treat, among other things, Alzheimer’s disease. While at first blush, this five-year, $230 million effort may seem noble, the ultimate motivation for this seemingly ecumenical event is suspect. Alzheimer’s disease affects some 5.4 million Americans, and according to a recent report from the RAND Corporation, costs Americans in the neighborhood of $200 billion each year to care for those afflicted. To context...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 10, 2014 Category: Neurologists Authors: gbadmin Tags: Science Alzheimer’s fat FDA Memantine NIH olive oil Vitamin E Source Type: blogs

Dangerous Meat and Dairy?
This study that caught so much attention in media doesn’t reflect in any way the health benefits of food choices like grass-fed beef and dairy products derived from organically raised cows. But leave it to those who write the headlines to draw simplified and biased conclusions with the intent to draw attention to their publications. It boggles the mind that a study such as this would dare to imply that the foods we have eaten for well over a million years are now scientifically determined to be unhealthful. If that were the case, how would we have made it this far? The important message revealed by the report was not art...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 7, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Science Alzheimer’s beef Cancer dairy diabetes grain-fed grass-fed meat Omega-3 Omega-6 protein Source Type: blogs

Patrick L.
Patrick’s “a-ha” moment is just great. Did any of you have a similar moment? – Dr. Perlmutter While reading Grain Brain, I had my “a-ha” moment in chapter 3. I immediately dumped out my sugar-filled coffee and poured a fresh black cup. In that moment, I swore off sugar and gluten completely. I focused solely on protein, healthy fats, and vegetables. In just the last four weeks I have lost six pounds. It’s been only thirty days and I feel completely different! My gas problem has disappeared, and I wake up refreshed and energized, rather than with a feeling of sickness. I have a new...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 6, 2014 Category: Neurologists Authors: gbadmin Tags: Success coffee Gluten protein sugar Vegetables weight loss Source Type: blogs

Ayla
The best part about Ayla’s story is how she finally learned that eating fat does NOT make you fat, a message I’ve working hard to spread. – Dr. Perlmutter I can personally attest to the drastic affects one experiences after removing wheat, grains and added sugar from her diet. I have lost 68 pounds (the first 55 pounds dropped within 6 months without exercise…simply from eliminating those 3 categories). More important though, is that most of my adult life I have been plagued by ridiculously high triglycerides.  When I first began reading Wheat Belly, my triglycerides were 546. On my lab results p...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 6, 2014 Category: Neurologists Authors: gbadmin Tags: Success exercise fat triglycerides weight loss wheat whole grains Source Type: blogs

Dairy: Dangerous or Delightful?
I’ve seen a lot of chatter here about the role of dairy in a Grain Brain lifestyle. Is it okay? How much can we have? What about Product X? Certainly, there is a role for dairy in the Grain Brain diet. However, that said, it is not a dairy-heavy lifestyle. Want a splash of whole milk or cream in your coffee? Go for it! A piece of organic goat cheese? That’s a-okay as well. Dairy can be enjoyed in moderation. What you want to avoid is low-fat and skim milk/dairy products. The reason for this is that, obviously, low-fat milk has less fat in it, and more lactose sugar. It should come as no surprise to learn that that suga...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 6, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Cheese dairy lactose Source Type: blogs

Diabetes and Dementia Risk
Over the past several years I have been calling attention to the profound relationship that exists between elevation of blood sugar and risk for developing dementia. This evolving body of knowledge stems from the incontrovertible evidence linking risk for dementia with having diabetes. More compelling is the evidence that demonstrates that this relationship becomes even more dramatic based on the length of time a person has suffered from diabetes. To be sure, I’m talking about type 2 diabetes which now affects about 28.6 million Americans. This is the type of diabetes that, in most people, is directly reflective of dieta...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - March 3, 2014 Category: Neurologists Authors: gbadmin Tags: Grain Brain Nutrition Science blood sugar Dementia diabetes exercise stress type 2 Type 2 diabetes Source Type: blogs

J.
The path that brought J to a gluten-free, LCHF diet is interesting to learn about. The fact that he is a fellow medical practitioner makes it even more so. – Dr. Perlmutter. I am a physician who has had intermittent diarrhea my entire life as did most of the members of my family. I simply lived with it. However, in my mid-forties, I started developing other symptoms, including inflammatory arthritis of my PIP joints of the hand (negative rheumatologic workup), odd fatigue, and three year’s worth of microscopic hematuria (negative urological workup). I was serum negative for the standard gluten markers and endoscop...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 28, 2014 Category: Neurologists Authors: gbadmin Tags: Success blood diabetes diarrhea Fatigue gluten free joint pain LCHF physician Taubes urine Source Type: blogs

Patricia A.
I had been experiencing puzzling health issues (fatigue, foggy brain, feeling off balance, chills, sweats) on-and-off for three years. A year ago, food intolerances were identified as the culprits. Glucose intolerance and high C-reactive protein were persistent problems. I eliminated gluten (along with other recommended problem foods based on an ALCAT test) from my diet, and, paired with a healthy fats diet, I believe this is responsible for the stark turnaround in my health. I’ve seen a loss of unwanted body fat and an across-the-board improvement in all of my health issues. -Patricia A. The post Patricia A. appeare...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 28, 2014 Category: Neurologists Authors: gbadmin Tags: Success Source Type: blogs

Alzheimer’s: A Disease of the Brain or the Body?
Recently, I had the chance to take part in a conversation with world-renowned experts in the fields of nutrition and neurology as a part of the program “The Agenda with Steve Paikin.” This panel came together to discuss what can be done to protect our brain health as we age. Thanks to the diversity of our backgrounds, there was a wealth of valuable conversation to be had, focusing on how we could further improve brain health. I was able to speak about the tenets of Grain Brain, from exercise to nutrition, and how these all play a role in optimizing the state of our brain. We all came at this topic from a different pers...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 28, 2014 Category: Neurologists Authors: gbadmin Tags: Videos Brain health neurology nutrition Source Type: blogs

Powerful Role of Ketone Fats in Brain Health and Alzheimer’s Treatment
Brain cells function with far greater efficiency when they are utilizing fat (ketones) as a fuel source as opposed to sugar. The exciting news is that scientists are now taking advantage of this finding in the actual treatment of Alzheimer’s disease, as you can see in this recent research publication. This research clearly substantiates the health benefits of a low-carb, high-fat diet as a powerful lifestyle change to achieve the goal of brain health and functionality. While there actually exists a pharmaceutical “medical food” based on the science explained in this report, you can boost the availability of ketones...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 26, 2014 Category: Neurologists Authors: gbadmin Tags: Grain Brain Science Alzheimer's disease Alzheimer’s coconut oil high-fat ketones LCHF low-carb MCT oil Source Type: blogs

Keep Yourself in Ketosis
When talking about a Grain Brain lifestyle, and the very similar ketogenic diet, it’s frequently mentioned that we are aiming to keep our bodies in ketosis. However, if you’re new to my work, it may be that you’re not exactly sure what ketosis is, or why we should be worrying about getting our body into this state. Allow me to explain. Ketones are a special type of fat that can stimulate the pathways that enhance the growth of new neural networks in the brain. A ketogenic diet is one that is high in fats, and this diet has been a tool of researchers for years, used notably in a 2005 study on Parkinson’s patients wh...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 25, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Science Antioxidant calories carbs fat hippocampus Ketogenic ketogenic diet mitochondria Parkinson's protein Source Type: blogs

Brain and Gut
To all of our readers, As you know, the fundamental premise of my work over the years has been to raise awareness of the relationship between nutrition and digestion, and how they support brain health and function. In my presentations to professionals, as well as my publications, I have endeavored to incorporate the most up-to-date research from around the world showing relevance to this thesis. And while there are journals dealing with brain science that may feature research dealing with nutrition, as well as nutritional and digestive publications that, on occasion, describe the role of nutrition in brain health, there is...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 24, 2014 Category: Neurologists Authors: gbadmin Tags: Resources Science autoimmunity Brain and Gut Cancer Dementia Depression digestive gut bacteria inflammation journals publications Source Type: blogs

Lori R.
It’s so good to hear stories like Lori’s, about how Grain Brain has brought answers and hope to those who have spent so many years looking for both. – Dr. Perlmutter My husband and I were in a weather-related car accident in January 2000 and both experienced severe closed head trauma. We lived in Pennsylvania at the time. By the grace of God, we recovered miraculously – although quickly realized (and accepted) that the damage done to our brains was going result in life-long implications for us. We made the decision to start a family a few years ago and have my husband be a stay-at-home dad; in part be...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 22, 2014 Category: Neurologists Authors: gbadmin Tags: Success allergies Anxiety brain injury carbs exercise fat head trauma skin Sleep Source Type: blogs

Mary O.
I’ve heard many responses from folks who have read Grain Brain, but to know that I brought tears to someone’s eyes is incredibly humbling. – Dr. Perlmutter I live in Australia and, by chance, came across Grain Brain whilst browsing iBooks for a good summer read. Once I got over the shock of the scientific revelations of your findings, I did three things: I cried with relief: I finally had some answers as to why my health was deteriorating in recent years (I am a 50 year old who exercises and followed a low fat/carb diet). I collected all my statins and hypertensive medication and threw them in the bi...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 22, 2014 Category: Neurologists Authors: gbadmin Tags: Success eneergy Hypertension Medication Sleep Statins sugar weight loss wheat Source Type: blogs

Carb Cravings Control
One of the things that I remain most impressed by is the way this community has banded together, both here and on my Facebook page. I’m amazed at how supportive everyone is, and the valuable discussion that takes place. That’s why I wanted to use this blog post to pose a question to all of you: how do you handle your carb cravings? Last week, I mentioned that gluten and sugar can act much like a drug, leaving those going off gluten, grains and sugar going through a period of “withdrawal.” I’ve seen a number of comments come in from folks looking for advice on how to deal with this period and prevent a slip-up. B...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 20, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition carb cravings drug Gluten Snack sugar withdrawal Source Type: blogs

Coffee Can Save Your Brain
Being a coffee drinker, and at risk for Alzheimer’s disease, as are we all, I was heartened by this study appearing in the Journal of Alzheimer’s Disease. The researchers followed 1,409 individuals, aged 65-79, for an average of 21 years. The study also looked at each individual’s dietary habits. At the end of the study, 48 of the subjects had developed Alzheimer’s disease. And it was shown that the risk for developing Alzheimer’s disease was reduced by an astounding 65% in those who drank 3-5 cups of coffee daily. The authors went so far as to suggest that “this finding might open possibilities for prevention ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - February 19, 2014 Category: Neurologists Authors: gbadmin Tags: Nutrition Science coffee NrF2 Resveratrol tea turmeric Source Type: blogs

Are Drugs Really The Way To Go For ADHD?
Over the past few months, I’ve produced several articles for the blog MindBodyGreen, a fantastic resource for anyone interested in learning more about topics and information pertaining to wellness.  You can find a completing listing of the articles I’ve written here on my website, but one in particular, published just last week, stirred up quite a conversation on social media. ADD/ADHD is an increasingly prevalent condition, one which the CDC recently said had been diagnosed in 11% of school-age children. As I note in my article, for the sake of comparison, we’re talking about a population the size of Kentucky. As a...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - November 20, 2013 Category: Neurologists Authors: gbadmin Tags: Science ADD ADHD Article Grain Brain MindBodyGreen Source Type: blogs

Grain Brain and the Seven Super Supplements
A brain-healthy, Alzheimer’s-fighting diet has properties that extend far beyond just decreasing your daily carb load. To truly provide your body  with  brain-boosting nutrients and vitamins that help stave off brain disease and other illnesses, you should consider a regular regimen of supplements. These seven supplements will go a long way towards helping you with prevention: DHA: An omega-3 fatty acid that represents more than 50% of the omega-3 fatty acids in the brain. Numerous studies link high levels of DHA with a decreased risk for dementia, Alzheimer’s and other brain diseases (view some of these studies her...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - November 19, 2013 Category: Neurologists Authors: gbadmin Tags: Grain Brain Nutrition alpa-lipoic acid coconut oil DHA probiotics Resveratrol Supplements turmeric Vitamin D Source Type: blogs