What are the dangers of taking Mucinex DM and Tylenol simultaneously?
Taking guaifenesen and dextromethorphan (Mucinex DM) with acetaminophen (Tylenol) should not pose a risk of drug-drug interactions, since the metabolism (clearance) of these products do not directly interfere with each other: Guaifenesin/Guaiphenesin Use as expectorant (thins mucus to make cough productive) Metabolized via hydrolysis: Unknown if metabolism via liver enzyme cytochrome P450 (CYP450) Dextromethorphan Use […] (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - November 11, 2018 Category: Consumer Health News Authors: Jane Tags: Science and Research Source Type: blogs
What are the dangers of taking Mucinex DM and Tylenol simultaneously?
Taking guaifenesen and dextromethorphan (Mucinex DM) with acetaminophen (Tylenol) should not pose a risk of drug-drug interactions, since the metabolism (clearance) of these products do not directly interfere with each other:
Guaifenesin/Guaiphenesin
Use as expectorant (thins mucus to make cough productive)
Metabolized via hydrolysis: Unknown if metabolism via liver enzyme cytochrome P450 (CYP450)
Dextromethorphan
Use as a cough suppressant (anti-tussive) and pseudobulbar affect (uncontrolled crying/laughing)
Metabolized via liver, CYP450 2D6
Acetaminophen/Paracetamol
Use to reduce fever and pain
Metabolized via liver, CYP...
Source: NAKEDMEDICINE.COM - November 11, 2018 Category: Consumer Health News Authors: Jane Tags: Science and Research Source Type: blogs
Do Mylan shareholders want the CEO to keep raising the price of the EpiPen?
We don’t know yet. Investors like a company to deliver positive earning results and increased guidance, and the recent negative public opinion has given investors a reason to sell, which was what happened. Currently $MYL is in “oversold” territory. Mylan 1 […] (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - October 30, 2016 Category: Consumer Health News Authors: Jane Tags: Business of Medicine Source Type: blogs
Do Mylan shareholders want the CEO to keep raising the price of the EpiPen?
We don’t know yet.
Investors like a company to deliver positive earning results and increased guidance, and the recent negative public opinion has given investors a reason to sell, which was what happened. Currently $MYL is in “oversold” territory.
Mylan 1 year and 5 year trends:
Keep in mind that 68% of Mylan is institutionally owned. Thus the market makers’ decisions will determine whether “shareholders” truly want the CEO to keep raising prices of the EpiPen. Retail (individual) investors’ outrage makes little difference to $MYL stock price, unless you happen to be an individual who owns millions of shar...
Source: NAKEDMEDICINE.COM - October 30, 2016 Category: Consumer Health News Authors: Jane Tags: Business of Medicine Source Type: blogs
Theranos ’ AACC Presentation: Not the Reboot We Were Hoping For
Move over, Edison: here comes miniLab. And yet: “Every piece of technology they presented has been known for many years, and exists in other platforms largely in the same configuration, or in some cases in much more compact form in competitor’s platforms.” ~ associate professor in U. Washington’s dept of laboratory medicine. Data has not […] (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - August 2, 2016 Category: Consumer Health News Authors: Jane Tags: Business of Medicine Source Type: blogs
Theranos ’ AACC Presentation: Not the Reboot We Were Hoping For
Move over, Edison: here comes miniLab.
And yet: “Every piece of technology they presented has been known for many years, and exists in other platforms largely in the same configuration, or in some cases in much more compact form in competitor’s platforms.” ~ associate professor in U. Washington’s dept of laboratory medicine.
Data has not been independently verified.
Holmes did not clarify that the 11 tests she presented would require at least 3-4 pricks if each prick yields only 160-uL amounts.
http://www.wsj.com/articles/theranos-founder-elizabeth-holmes-introduces-new-blood-testing-device-1470089582
Thera...
Source: NAKEDMEDICINE.COM - August 2, 2016 Category: Consumer Health News Authors: Jane Tags: Business of Medicine Source Type: blogs
Killing Zika Virus Carrying Mosquitoes with Gene Drives?
Genetically engineering out the lives of pests is not a new idea. The idea of leveraging sexual reproduction to pass specific gene changes (mutations or alterations) through entire populations to control pests has been proposed as far back as the 1940s, for example, A Strain of the Mosquito Aedes aegypti Selected for Susceptibility to the […] (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - June 27, 2016 Category: Consumer Health News Authors: Jane Tags: Science and Research Source Type: blogs
Killing Zika Virus Carrying Mosquitoes with Gene Drives?
Genetically engineering out the lives of pests is not a new idea. The idea of leveraging sexual reproduction to pass specific gene changes (mutations or alterations) through entire populations to control pests has been proposed as far back as the 1940s, for example, A Strain of the Mosquito Aedes aegypti Selected for Susceptibility to the Avian Malaria Parasite Plasmodium lophurae.
Evolutionary geneticist Austin Burt was credited with the method of cutting DNA to reduce populations of disease-spreading species and the associated idea of “Gene drives”. The central idea behind a gene drive is to ensure that the engineere...
Source: NAKEDMEDICINE.COM - June 27, 2016 Category: Consumer Health News Authors: Jane Chin Tags: Science and Research Source Type: blogs
Transgender, Cisgender: Where does gender identity come from?
“What causes a person to be transgender”? You might as well ask the question, “What causes a person to be (a) gender?” These questions ask the exact same thing.
If you are a cisgender person wanting to understand what causes a person to be transgender, then ask yourself, “What causes me to identify as the gender I am?” The answer goes to the heart of the gender “identity” — what makes a person know “the gender” that person is and what makes a person cisgender or transgender, comes from the same “root”.
For a cisgender person, the answer may be easy: look down and you have your answer. But this ans...
Source: NAKEDMEDICINE.COM - June 22, 2016 Category: Consumer Health News Authors: Jane Chin Tags: Science and Research Source Type: blogs
How Antibiotics Work
Antibiotics work according to the mechanism of action (what the drug “targets” in microbes or how the drug “works” in the microbe) that is driven by the drug’s distinguishing chemical structure. Chemical structures also define the “classification” of antibiotics. If you hear doctors talk about “macrolides” versus “quinolones”, they are talking about families of drugs […] (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - March 16, 2016 Category: Consumer Health News Authors: Jane Tags: Antibiotics Business of Medicine Critical Consumer Source Type: blogs
How Antibiotics Work
Antibiotics work according to the mechanism of action (what the drug “targets” in microbes or how the drug “works” in the microbe) that is driven by the drug’s distinguishing chemical structure.
Chemical structures also define the “classification” of antibiotics. If you hear doctors talk about “macrolides” versus “quinolones”, they are talking about families of drugs (not “one” specific drug) and they are referring to the way each family of drugs targets microbes.
When you hear about “generations” of an antibiotic, this means the chem...
Source: NAKEDMEDICINE.COM - March 16, 2016 Category: Consumer Health News Authors: Jane Tags: Antibiotics Business of Medicine Critical Consumer Source Type: blogs
Theranos ’ Elizabeth Holmes is Not a Liar
(Via Quora’s Is Elizabeth Holmes a liar?)
The Theranos story has gone from bad to worse, first from the Wall Street Journal “expose” that Holmes during a live blogging event equated to “tabloid” journalism, then from a series of very public disengagements with partner corporations, and now — complying with a Herculean FDA request. This is causing some in the public to ask whether Holmes is a mastermind in a fairytale of scientific triumph.
No. Holmes is not a liar.
Holmes made bad business decisions and painted herself into a corner.
Holmes is in the class of executives that are technol...
Source: NAKEDMEDICINE.COM - January 30, 2016 Category: Consumer Health News Authors: Jane Chin Tags: Business of Medicine Source Type: blogs
Theranos’ Elizabeth Holmes is Not a Liar
(Via Quora’s Is Elizabeth Holmes a liar?)
The Theranos story has gone from bad to worse, first from the Wall Street Journal “expose” that Holmes during a live blogging event equated to “tabloid” journalism, then from a series of very public disengagements with partner corporations, and now — complying with a Herculean FDA request. This is causing some in the public to ask whether Holmes is a mastermind in a fairytale of scientific triumph.
No. Holmes is not a liar.
Holmes made bad business decisions and painted herself into a corner.
Holmes is in the class of executives that are technol...
Source: NAKEDMEDICINE.COM - January 30, 2016 Category: Consumer Health News Authors: Jane Chin Tags: Business of Medicine Source Type: blogs
The Theranos Problem in One WSJ Graphic
Now that Theranos is allegedly/denying-trying to raise money, speculations continue as to whether it could survive the Wall Street Journal article, Hot Startup Theranos Has Struggled With Its Blood-Test Technology, or whether a big industry player may swoop down to acquire the company. In terms of “who would be audacious (to use a polite word) … Continue reading The Theranos Problem in One WSJ Graphic → (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - November 23, 2015 Category: Consumer Health News Authors: Jane Chin Tags: Activism & Advocacy Affordable Healthcare Business of Medicine entrepreneurship Truth in Medicine Source Type: blogs
What Pharma Companies Need
The next first-in-class blockbuster drug. Favorable pricing and reimbursement by government. Longer patent life. Orphan drug designations. Coverage on all formularies. (Source: NAKEDMEDICINE.COM)
Source: NAKEDMEDICINE.COM - June 14, 2015 Category: Consumer Health News Authors: Jane Chin Tags: Science and Research Source Type: blogs
