When to revascularise in stable CAD: A Single slide presentation
This graph is a rare treasure in CAD therapeutics (fished out from essentially meaningless, often dangerous statistical curves littered in chronic CAD literature) that elegantly shows us the complexities involved in the revascularization of ischemic hearts with risks and benefits criss-cross each other. Our job is to identify, that critical point in a given patient’s CAD timeline. To make things difficult, this point is a moving target and makes this delicate clinical exercise truly complicated. http://assets.escardio.org/assets/presentations/OTHER2013/Coronary-physiology/213-PIJLS.pdf It conveys a simple message in ...
Source: Dr.S.Venkatesan MD - April 2, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized medical vs pci vs surgery in cad revascularisation in cad wisdom slides in cardiology Source Type: blogs

Be happy with the “ H ” Index of Hippocrates
“Publish or perish “ This sound bite is regularly uttered by all academic leads in any university or medical school. I don’t know, why this bothers me. Looking back, many of our mentors & professors never had any great publications. Still, they were extraordinary teachers and wonderful clinicians with great wisdom. They created generations of high-quality doctors who are present all over the globe now. Is scientific publication that important in a doctor’s life? After pondering for quite some time, got a hazy answer to that query in one of my sleepless early morning academic dreams. Hi...
Source: Dr.S.Venkatesan MD - March 5, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology quotes cardiology-ethics Uncategorized bmj future of medicine google scholor H index hippocrates ethics Hippocratic oath i Index Impact factor jama network kos island lance medical ethics medical research issues Source Type: blogs

Be happy with the “ H ” Index of Hippocrates
“Publish or perish “ This sound bite is regularly uttered by all academic leads in any university or medical school. I don’t know, why this bothers me. Looking back, my mentors in Coimbatore medical college (or even the more prestigious MMC, Chennai) never had any good publications which I could recall. Is scientific publication that important in a doctor’s life? After pondering for quite some time, got a hazy answer to that query in one of my sleepless early morning academic dreams. Hippocrates was one of the applicants for the post of professor of medicine at Harvard medical school.His a...
Source: Dr.S.Venkatesan MD - March 2, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology quotes cardiology-ethics Uncategorized bmj future of medicine H index hippocrates ethics Hippocratic oath i Index Impact factor jama network kos island lance medical ethics medical research issues nejm peer revie Source Type: blogs

Futuristic cardiology: Fishing a failing heart !
A path-breaking research is coming up from Jhon Paulson school of engineering, Harvard. It is all about a tiny lab-made bio-hybrid fish that is mechanically engineered with cardiac stem cells. It can generate enough mechanical force that can transform into a biological organ (or assistance)to the heart. Early lab experiments are exciting. We will soon see a stem cell-enriched bio-fish that will dance to the tunes of the cardiac cycle. (See the video below)  Final message Will it become real? or a just a grandeur thought? We have just done Xeno heart transplantat...
Source: Dr.S.Venkatesan MD - February 20, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized bio organism as artificial organ donor future of cardiology heart transplanation xeno transplantation Source Type: blogs

Lessons of pandemic : Tackling Covid is much easier task, than the onslaught of Science !
This article  by Dr. Anand Krishnan, Professor of  community medicine, AIIMS New Delhi, has some enlightening content https://timesofindia.indiatimes.com/india/whys-pandemic-policymaking-still-short-of-science/articleshow/88650912.cms (Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - February 12, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Curve of wisdom in ACS : Open Cath lab doors may mean nothing , if the windows are closed !
“We have a 24/7 cath lab with an open door policy. Our cardiologist arrives at 15 minutes’ notice. Door to balloon time is less than 60-90 minutes”,  “Great, so, you can always offer a successful treatment for STEMI” “No, that we can never guarantee.”   “Oh, It Is not the answer, I  expected” “I agree, it sounds disappointing, but. truths are less pleasing. What I am trying to say is, there are a number of factors other than the availability of a grand cath lab and agile and effortless hands, that try to reperfuse the myocardium in distress.  I ...
Source: Dr.S.Venkatesan MD - February 1, 2022 Category: Cardiology Authors: dr s venkatesan Tags: acute coroanry syndrome acute coronary syndrome Cardiology -Criteria Cardiology -guidelines cardiology -Therapeutics Cardiology -unresolved questions acc aha esc scai gudilines acs acs management evidence based cardiology open artery h Source Type: blogs

Post-modern science needs more Innovation or regulation?
“It needs both. obviously”. “Which is difficult? Innovation or regulation? The answer is easy, am I right? “If we are not able to regulate science …what is the purpose of magnificent Inventions & Innovations?” “Who will take the responsibility for all motivated false research and resultant adversaries?  Final message Is shutting down (or grossly down-regulating ) research an option? Foolish option…but Who Initiated, funded, and masterminded the gain in function experiment with the innocent RNA viruses which were happi...
Source: Dr.S.Venkatesan MD - January 23, 2022 Category: Cardiology Authors: dr s venkatesan Tags: bio ethics medical quotes dr venkatesan quotes ethics in medical research modern medical research Nobel prize in science Source Type: blogs

Testing times for EBM : NEJM gets ready & begins a new journey
The New England Journal of Medicine (NEJM) the premier journal in medicine originated two centuries ago, in 1811, when  John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the New England Journal of Medicine and Surgery and Collateral Branches of Science as a medical and philosophical journal.  Subsequently, the first issue of the New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science was published in January 1812. In 1921, the Massachusetts Medical Society (MMS) purchased the Journal for US$1 and, in 1928, rename...
Source: Dr.S.Venkatesan MD - January 19, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized bmj ebm ethics in science evidence based medicine lancet medical education nejm new nejm journal Source Type: blogs

Dr Braunwald ’ s Grand rounds on future of cardiology
What is in store for the future of cardiology as of 2022? Here is one of the rare lectures (A grand rounds by Houston Methodist)  by legendary cardiologist Dr. Euegne Braunwald who shares his wisdom, vision, and research and finally his advice for the generation next cardiologist.   For those, who are short of time to listen to the father of modern-day cardiology, let me share a preview. The talk is divided into 6 subsets. Polygenic risk score (PRS)  Dr. Braunwald talks about how genetic risk profiling and risk factor interaction will help us identify susceptible populations. Here, ...
Source: Dr.S.Venkatesan MD - January 16, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized artificial intelligence chip clonal hematopoietic independent potential chip Dr Eugene Braunwald future of cardiology dr s venkatesan great lectures in cardiology polygenic risk factors Source Type: blogs

In AF why the ventricular rate is irregular?
Here is a case report from Dr. Brugada’s group. What is your diagnosis? Source & Courtesy Sergio Richter, Joseph Brugada et all , 100(1), 154–156. doi:10.1016/j.amjcard.2007.02.067 Whoever diagnosed AF in the above ECG need not feel bad. The rhythm is not AF, though it mimics very closely. In cardiology, especially in electrophysiology, we can get surprises on a daily basis. (Read below) Why the ventricular rate is irregular in AF? Atrial fibrillation (AF)  may sound like a  simple clinical arrhythmia until we ask this delicate question. The traditional and fairly accepted answer is that, AV node w...
Source: Dr.S.Venkatesan MD - January 14, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Atrial fibrillation Cardiology Patho physiology Infrequently asked questions in cardiology (iFAQs) AV node anatomy AVNRT and AF Dual AV nodal path way poly av nodal pathway Pseudo atrial fibrillation Source Type: blogs

Knowledge check in Brugada syndrome : A rapid fire session
A 5-minute session: Answers are my own. Please cross-check. 1. Is Brugada syndrome clinical or ECG diagnosis? Always clinical. Never get confused on this. 2. Spontaneous type 1 vs Induced Type 1 (from type 2) which carries more risk? Both are risky since they are close cousins. But, spontaneous type 1 is the dreaded devil.  3. Is Brugada primarily a defect of myocardial depolarization or repolarisation? Not clear. Often in both. In fact a mismatch between them. (Don’t ask how Na+ Channel defect affects repolarisation !) 4. Is Brugada VT is monomorphic, polymorphic? Both. What determines m...
Source: Dr.S.Venkatesan MD - January 5, 2022 Category: Cardiology Authors: dr s venkatesan Tags: cardiac electrophysiology cardiology -Therapeutics Cardiology -unresolved questions Cardiology-Arrhythmias early repolarisation syndrome Electro physiology Electrocardiography-ECG ICD and Pacemakers amiodarone for brugada brugada syndrom Source Type: blogs

Top Cardiology and Heart Disease Blogs in 2021
Surprised to find this site, in the 5th slot in the global rankings by feedspot search engine. Never Imagined, when I started my scribblings way back in 2008 , It will be listed along with American heart asssociation, BMJ and others in top 10. I need to thank the readers who make this happen. Thank you all. (PS :I am not sure on what basis these rankings were done though, still it adds some energy, that keeps this site running) https://blog.feedspot.com/heart_blogs/ (Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - January 1, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Top 60 Cardiology and Heart Disease Blogs in 2021
Surprised to find this site, in the 5th slot in the global rankings by feedspot search engine. Never Imagined, when I started my scribblings way back in 2008 , It will be listed along with American heart asssociation, BMJ and others in top 10. I need to thank the readers who make this happen. Thank you all. (PS :I am not sure on what basis these rankings were done though, still it adds some energy, that keeps this site running) https://blog.feedspot.com/heart_blogs/ (Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - January 1, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

A new year brings “ New hope ”
After a hectic two years , let us pray & believe, the good old times will be back in our life. (Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - January 1, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Cardiac failure Info desk :Diuretics never save lives, while Dapagliflozin does it in style !
An Interaction in IMCU How is Mr. K, who was shifted from ward 102 ? Yes sir, It was acute decompensated LV failure, Patient was in impending pulmonary edema. In fact, he developed. He is fine now, How did he come around? He was too sick I thought. “Just pushed 60 mg Frusemide IV, luckily he also had good BP, so with an infusion of NTG, titrated Carvedilol a little bit, he came out nicely. I guess it is Ischemic DCM”. “Good, You have done a nice job” “Don’t make me embarrassed sir. It is such a routine in our ER.  To make him curious, I asked “Which drug do you think that s...
Source: Dr.S.Venkatesan MD - December 17, 2021 Category: Cardiology Authors: dr s venkatesan Tags: cardiac failure Cardiology -guidelines cardiology -Therapeutics cardiology wisdom cardiology-ethics Cardiology-Land mark studies Ethics in Medicine evidence based cardiology acc aha esc guidelines on heart failure bumatanide Cardiac fa Source Type: blogs