Wim Hof Method decreases IL-6, can it prevent IL-6-induced cytokine storm in COVID19?
A subgroup of patients with severe COVID-19 may have a cytokine storm syndrome.A cytokine profile in severe COVID-19 disease includes increased interleukin (IL)-2, IL-7, granulocyte-colony stimulating factor, interferon-gamma inducible protein 10, monocyte chemoattractant protein 1, macrophage inflammatory protein 1-alpha, tumour necrosis factor-alpha, and IL-6. Mortality might be due to virally driven hyperinflammation.Anti-IL-6 antibody tocilizumab (IL-6 receptor blocker) has been used in patients with COVID-19 pneumonia and elevated IL-6. Other agents, such as sarilumab and siltuximab, which also target the IL-6 pathway...
Source: Clinical Cases and Images - Blog - April 2, 2020 Category: Universities & Medical Training Tags: COVID-19 Wim Hof Method Source Type: blogs
How to Break the Coronavirus Anxiety Cycle
From the psychiatrist Judson A. Brewer, M.D., Ph.D. in the NYTimes:Anxiety and its close cousin, panic, are both born from fear and uncertainty. We have plenty of that with the current COVID-19 pandemic.If information is lacking, our prefrontal cortex lays out different scenarios about what might happen. Some of these scenarios can be pretty scary.Anxiety is contagious. The spread of emotion from one person to another is called social contagion. "People can sneeze on your brain", says Dr Jud. "Our own anxiety can be cued or triggered simply by talking to someone else who is anxious. Their fearful words are like a sneeze la...
Source: Clinical Cases and Images - Blog - March 23, 2020 Category: Universities & Medical Training Tags: COVID-19 Psychology Source Type: blogs
Glycemic index (GI) and glycemic load (GL) for 1,800 foods
Glycemic index (GI) and glycemic load (GL) values determined in subjects with normal glucose tolerance: 2008: 58-page PDF from Diabetes Care 2008 Dec; 31(12): 2281-2283. https://doi.org/10.2337/dc08-1239https://care.diabetesjournals.org/content/diacare/suppl/2008/09/18/dc08-1239.DC1/TableA1_1.pdfReferences:https://care.diabetesjournals.org/content/31/12/2281.figures-onlyhttps://www.health.harvard.edu/diseases-and-conditions/glycemic-index-and-glycemic-load-for-100-foods
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Source: Clinical Cases and Images - Blog - January 13, 2020 Category: Universities & Medical Training Authors: noreply at blogger.com (Unknown) Tags: Diabetes Endocrinology Food Source Type: blogs
Intermittent metabolic switching (IMS) via fasting: is it for you and how to do it?
Intermittent metabolic switching (IMS) via fasting is getting mainstream, spearheaded by an all-positive NEJM review published on Christmas Day 2019:https://www.nejm.org/doi/full/10.1056/NEJMra1905136The article is ranked at the 99th percentile compared to other NEJM articles as of 01-02-2020,https://www.nejm.org/doi/metrics/10.1056/NEJMra1905136#social_mediaFasting is an example of hormesis. Hormesis is a term used by toxicologists to refer to a biphasic dose –response to an environmental agent: 1. a low dose stimulation or beneficial effect, 2. a high dose inhibitory or toxic effect. In the fields of biology and medici...
Source: Clinical Cases and Images - Blog - January 3, 2020 Category: Universities & Medical Training Tags: Fasting Longevity Source Type: blogs
How Balding Became Big Business, and the market is expected to grow even further - WSJ video
How Balding Became Big Business - WSJ video: Only 2 medications are FDA-approved as of 2019: minoxidil and finasteride:References:https://on.wsj.com/32SeoPz
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Source: Clinical Cases and Images - Blog - October 3, 2019 Category: Universities & Medical Training Tags: Dermatology Source Type: blogs
How to Take Care of Your Eyes as You Age: be aware of GMC: Glaucoma, Macular degeneration, Cataract
FromConsumer Reports:GlaucomaMore than 2 million Americans have glaucoma, but 50% know it. Glaucoma often goes undiagnosed because it causes no symptoms until vision declines, at which point treatment no longer helps.People aged 40-60 should be examined by an optometrist every 3-5 years; those older than 60 need an eye exam every 1-2 years.Many eye doctors screen for glaucoma with tonometry (measures eye pressure) but that ’s not enough. Relying only on intraocular pressure (IOP) when screening for glaucoma could miss up to 50% of all cases. Theexam should also include an ophthalmoscopy, which involves examining your opt...
Source: Clinical Cases and Images - Blog - October 2, 2019 Category: Universities & Medical Training Tags: Ophthalmology Source Type: blogs
Keep Things Simple For A Healthy, and Hopefully Longer, Life
By my former colleague at the University of Chicago,John Schumann: Keep Things Simple For A Healthy, Long Life:1. Get enough sleep.2. Move your body throughout the day.3. Eat well — a healthy assortment of foods. Mostly plants, and not too much.4. Interact socially. Isolation is not good for the body, soul or mind.5. Take some time to reflect on what you are grateful for.Interventions that promote longevity, remembered by mnemonic:DEEP purple - “eat colorful plant foods:Dietary modification,Exercise, activeEngagement,Purposeful living (click here toenlarge the image).References:https://www.npr.org/sections/health-shots...
Source: Clinical Cases and Images - Blog - October 1, 2019 Category: Universities & Medical Training Source Type: blogs
