Study Questions ‘ Lower Is Better ’ For Cholesterol
–No added benefit for statin patients who reached very low LDL levels A large observational study suggests that moderate lowering of LDL may be just as effective as intensive lowering. “Our results do not provide support for a blanket principle that lower LDL cholesterol is better for all patients in secondary prevention,” the authors conclude....Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 20, 2016 Category: Cardiology Authors: Larry Husten Tags: Policy & Ethics Prevention, Epidemiology & Outcomes cholesterol guidelines LDL statins targets Source Type: blogs

Study Questions ‘Lower Is Better’ For Cholesterol
–No added benefit for statin patients who reached very low LDL levels A large observational study suggests that moderate lowering of LDL may be just as effective as intensive lowering. “Our results do not provide support for a blanket principle that lower LDL cholesterol is better for all patients in secondary prevention,” the authors conclude....Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 20, 2016 Category: Cardiology Authors: Larry Husten Tags: Policy & Ethics Prevention, Epidemiology & Outcomes cholesterol guidelines LDL statins targets Source Type: blogs

Cholesterol Skeptics Launch Another Attack
–But most experts say their study is highly flawed Once again, a group of cholesterol skeptics has published an inflammatory attack on the cholesterol hypothesis. But critics say that the paper is deeply flawed and should not be used to influence treatment or policy decisions. In a paper published in BMJ Open, Uffe Ravnskov, MD,...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 15, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes cholesterol statins Source Type: blogs

Clinical Trial Expert ’ s Deep Dive Into The Important New Liraglutide Trial
–Sanjay Kaul plunges into the LEADER data pool There will be a lot of discussion in the near future about the LEADER trial, the large new trial assessing cardiovascular outcomes with liraglutide (Victoza, Novo Nordisk). The trial is the latest in a series of large CVOTs with new diabetes drugs showing benefit— or at least...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 13, 2016 Category: Cardiology Authors: Larry Husten Tags: Diabetes People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes CVOT LEADER liraglutide Victoza Source Type: blogs

Clinical Trial Expert’s Deep Dive Into The Important New Liraglutide Trial
–Sanjay Kaul plunges into the LEADER data pool There will be a lot of discussion in the near future about the LEADER trial, the large new trial assessing cardiovascular outcomes with liraglutide (Victoza, Novo Nordisk). The trial is the latest in a series of large CVOTs with new diabetes drugs showing benefit— or at least...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 13, 2016 Category: Cardiology Authors: Larry Husten Tags: Diabetes People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes CVOT LEADER liraglutide Victoza Source Type: blogs

First PCSK9 Outcome Trial Results Pushed Back To 2017
Uptake of the new drugs likely to lag without strong outcomes data. Uptake of the new drugs likely to lag without strong outcomes data.Uptake of the new drugs likely to lag without strong outcomes data.   –Uptake of the new drugs likely to lag without strong outcomes data. There’s probably nothing more eagerly awaited in cardiovascular...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 8, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes Amgen CVOT Fourier PCSK9 Repatha Source Type: blogs

Documents Reveal Rogue Laboratory Company ’ s Unorthodox Billing Practices
–Promised in writing to not bill patients, then changed its tune Records and emails newly posted on the web by a physician document the strategy used by a controversial new laboratory company to bypass laws and major safeguards designed to prevent fraud. Nearly 2 years ago, it became known that the federal government was investigating...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 8, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Health Diagnostic Laboratory True Health Diagnostics zombie lab Source Type: blogs

Documents Reveal Rogue Laboratory Company’s Unorthodox Billing Practices
–Promised in writing to not bill patients, then changed its tune Records and emails newly posted on the web by a physician document the strategy used by a controversial new laboratory company to bypass laws and major safeguards designed to prevent fraud. Nearly 2 years ago, it became known that the federal government was investigating...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 8, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Health Diagnostic Laboratory True Health Diagnostics zombie lab Source Type: blogs

Prominent Cardiologist And ESC Presidential Candidate Found Guilty Of Fraud
Karl-Heinz Kuck, a prominent German cardiologist and candidate for the presidency of the European Society of Cardiology, has been found guilty of fraud. He received a fine of 100,000 Euros and a prison sentence of one year. His prison sentence has been suspended as long as he does not commit additional fraud. According to multiple reports in...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 7, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Bax ESC ESC presidency Kuck Poldermans Source Type: blogs

FDA Proposes Voluntary Sodium Cuts by Food Industry
–AMA, AHA, ACC, etc voice support, but not everyone agrees. After decades of discussion and inaction, the FDA today took a first concrete step toward reducing sodium levels in the general population: It issued draft guidance for voluntary sodium reduction targets for the food industry. The FDA said that the new recommendations come from “leading...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - June 1, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes AHA CDC FDA salt sodium Source Type: blogs

Women with Migraine Face Increased CV Risk
–But clinical implications are unclear since there’s no known mechanism Women who have migraine headaches have a significantly increased risk of cardiovascular disease, according to new results from a large observational study published in the BMJ. Earlier studies have established a strong link between migraine and stroke, which the the new study now extends to...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - May 31, 2016 Category: Cardiology Authors: Larry Husten Tags: Prevention, Epidemiology & Outcomes Cardiovascular disease migraine stroke women Source Type: blogs

New Anticoagulant May Cut VTE In Medically Ill
–Generally positive results for Portola’s betrixaban, despite missed key endpoint Betrixaban may yet become the first new oral anticoagulant to gain approval for extended venous thromboembolism (VTE) prophylaxis in the important and underserved group of medically-ill patients, even though its pivotal trial was damaged by a self-inflicted statistical wound. There were consistent differences in favor of...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - May 27, 2016 Category: Cardiology Authors: Larry Husten Tags: Prevention, Epidemiology & Outcomes anticoagulants betrixaban medical patients oral antcoagulant VTE Source Type: blogs

The American Heart Association ’ s Strong Stance Against Science
Once again the American Heart Association has taken a strong stance against science. Of course, that’s not how the AHA phrases it. In its own words the AHA says it “strongly refutes the findings” of a “flawed study” which “you shouldn’t use… to inform yourself about how you’re going to eat.” But in fact the...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - May 25, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes Uncategorized american heart association guidelines salt Source Type: blogs

The American Heart Association’s Strong Stance Against Science
Once again the American Heart Association has taken a strong stance against science. Of course, that’s not how the AHA phrases it. In its own words the AHA says it “strongly refutes the findings” of a “flawed study” which “you shouldn’t use… to inform yourself about how you’re going to eat.” But in fact the...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - May 25, 2016 Category: Cardiology Authors: Larry Husten Tags: People, Places & Events Policy & Ethics Prevention, Epidemiology & Outcomes Uncategorized american heart association guidelines salt Source Type: blogs

Flu Vaccine May Benefit Heart Failure Patients
–Studies find fewer hospitalizations and less dementia after vaccination Two new observational studies offer new evidence that heart failure patients may benefit from the flu vaccine. The studies were presented in Florence, Italy, at the Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure. In the first study Kazem Rahimi (University of...Click here to continue reading... (Source: CardioBrief)
Source: CardioBrief - May 24, 2016 Category: Cardiology Authors: Larry Husten Tags: Heart Failure Prevention, Epidemiology & Outcomes dementia flu vaccine Source Type: blogs