From The FDA: "Oversight of Clinical Investigations - A Risk-Based Approach to Monitoring"
Oversight of Clinical Investigations — A Risk-Based Approach to Monitoring (Guidance for Industry)FDAAugust 2013 Read the document here (Source: BrainBlog)
Source: BrainBlog - August 7, 2013 Category: Neurologists Source Type: blogs

"Andrew Marr, After The Stroke"
Andrew Marr, after the stroke: 'I'm going to be sweeter all round'The TV presenter suffered a severe stroke after a strenuous workout in January. On the eve of his return to our screens he talks of his fight back to healthRobert McCrumThe ObserverSaturday 3 August 2013Read the article (Source: BrainBlog)
Source: BrainBlog - August 4, 2013 Category: Neurologists Source Type: blogs

Memory "Engineering"
From the Scientific American website: The Era of Memory Engineering Has ArrivedHow neuroscientists can call up and change a memory By Jason CastroTuesday, July 30, 2013 Read the posting (Source: BrainBlog)
Source: BrainBlog - August 2, 2013 Category: Neurologists Source Type: blogs

Memory and the Perception of Place
From The Atlantic: Cities: How Memory Alters Our Perception of Placeby EMILY BADGERAug 01, 2013 Read the article (Source: BrainBlog)
Source: BrainBlog - August 2, 2013 Category: Neurologists Source Type: blogs

Neuropsychology Abstract of the Day: Neuropsychology Education
Discussions of and recommendations for the training of clinical neuropsychologists exist at the doctoral, internship, and post-doctoral level. With few exceptions, the literature on undergraduate preparations in clinical neuropsychology is sparse and lacks empirical evidence. In the present study, graduate-level faculty and current trainees completed surveys about graduate school preparations. Faculty expectations of minimum and ideal undergraduate training were highest for research methods, statistics, and assessment. Preferences for "goodness of fit" also emerged as important admissions factors. These results o...
Source: BrainBlog - August 2, 2013 Category: Neurologists Source Type: blogs

Alzheimer's Disease: Nature's "Neuropod" Podcast for July 2013
The July edition of "Neuropod" includes a discussion of risk factors in Alzheimer's disease. Access the podcast here (Source: BrainBlog)
Source: BrainBlog - August 1, 2013 Category: Neurologists Source Type: blogs

NIH Launches Neurological Drug Development Projects
From the NIH: NIH launches neurological drug development projectsWednesday, July 31, 2013, 8 a.m. EDT Read the press release (Source: BrainBlog)
Source: BrainBlog - August 1, 2013 Category: Neurologists Source Type: blogs

Mouse Hippocampus and Memory
The cover of this week's Science: About the research study represented by the cover: here (Source: BrainBlog)
Source: BrainBlog - July 26, 2013 Category: Neurologists Source Type: blogs

A Review of the DSM-5 in the "London Review of Books"
Lost in the ForestIan HackingLondon Review of Books08 August 2013 Read the article (Source: BrainBlog)
Source: BrainBlog - July 25, 2013 Category: Neurologists Source Type: blogs

Alzheimer's: CMS Proposed Decision Memo for Beta Amyloid Positron Emission Tomography in Dementia and Neurodegenerative Disease
Proposed Decision Memo for Beta Amyloid Positron Emission Tomography in Dementia and Neurodegenerative DiseaseCMS.gov03 July 2013 Read the memo (Source: BrainBlog)
Source: BrainBlog - July 23, 2013 Category: Neurologists Source Type: blogs

Photoreceptors from Embryonic Stem Cells
From The Guardian:Embryonic stem cells could help restore sight to blindPhotoreceptors grown from embryonic stem cells have been successfully implanted in the retinas of blind miceAlok Jha, Science CorrespondentThe Guardian Sunday 21 July 2013 18.00 BST Read the article (Source: BrainBlog)
Source: BrainBlog - July 22, 2013 Category: Neurologists Source Type: blogs

Alzheimer's Disease: AAIC Review from "Fierce Biotech"
Alzheimer's roundup: Investigators carve out small gains against a brutal diseaseFierce BiotechBy John CarrollJuly 18, 2013 Read the article (Source: BrainBlog)
Source: BrainBlog - July 18, 2013 Category: Neurologists Source Type: blogs

Aggressive Behavior in Dementia
From The New York Times blog "The New Old Age": When Aggression Follows DementiaBy PAULA SPANJuly 12, 2013, 4:38 pm Read the article (Source: BrainBlog)
Source: BrainBlog - July 13, 2013 Category: Neurologists Source Type: blogs

Neuropsychology Abstract of the Day: Aging
CONCLUSIONS: Higher level of very late-life physical activity was associated with a lower risk of subsequent dementia in oldest-old women. These findings support future studies for late-life physical activity interventions for the prevention of dementia among oldest-old women.PMID: 23831179 [PubMed - as supplied by publisher] (Source: BrainBlog)
Source: BrainBlog - July 9, 2013 Category: Neurologists Source Type: blogs

Neuropsychology Abstract of the Day: Neuropsychological Assessment
CONCLUSIONS: The WTT demonstrated excellent concurrent validity with existing 'Gold Standard' assessments of cognitive impairment. We believe that this instrument will prove to be a valuable additional screening assessment in epidemiological, primary care, specialist mental health or clinical investigations. Copyright © 2013 John Wiley & Sons, Ltd.PMID: 23824787 [PubMed - as supplied by publisher] (Source: BrainBlog)
Source: BrainBlog - July 6, 2013 Category: Neurologists Source Type: blogs

Neuropsychology Abstract of the Day: Suicidal Behavior and Semantic Dementia
Suicidal Behavior in Dementia: A Special Risk in Semantic Dementia.American Journal of Alzheimer's Disease and Other Dementias. 2013 Jul 1;Sabodash V, Mendez MF, Fong S, & Hsiao JJAbstractBackground: Some studies report a low suicide risk in general dementia and in Alzheimer's disease (AD).Objective:To evaluate suicidal behavior among patients with semantic dementia (SD), a disorder that impairs semantic knowledge. Methods: We reviewed the presence of active suicidal behavior and related factors among 25 patients with SD compared to 111 age-matched patients with early-onset AD. Results: In all, 5 (20%) patients with SD...
Source: BrainBlog - July 5, 2013 Category: Neurologists Source Type: blogs

The "Dopamine Is ___" Craze
"Dopamine Is ___" By Bethany BrookshireSlate.comPosted Wednesday, July 3, 2013, at 8:06 AM Read the article (Source: BrainBlog)
Source: BrainBlog - July 4, 2013 Category: Neurologists Source Type: blogs

Lifestyle and Dementia
Active brain 'keeps dementia at bay'By Helen BriggsBBC News3 July 2013 Last updated at 19:54 ET Read the article (Source: BrainBlog)
Source: BrainBlog - July 4, 2013 Category: Neurologists Source Type: blogs

alpha-synuclein
From the NIH: Altered protein shapes may explain differences in some brain diseasesWednesday, July 3, 2013, Noon EDT NIH-funded study finds that various strains of alpha-synuclein have diverse effects in neurons Read the press release (Source: BrainBlog)
Source: BrainBlog - July 3, 2013 Category: Neurologists Source Type: blogs

Neuropsychology Abstract of the Day: Computerized Cognitive Testing
This study compared the relationship between computer experience and performance on computerized cognitive tests and a traditional paper-and-pencil cognitive test in a sample of older adults (N = 634).METHOD: Participants completed computer experience and computer attitudes questionnaires, three computerized cognitive tests (Useful Field of View (UFOV) Test, Road Sign Test, and Stroop task) and a paper-and-pencil cognitive measure (Trail Making Test). Multivariate analysis of covariance was used to examine differences in cognitive performance across the four measures between those with and without computer experience after...
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Alzheimer Disease: A Self-Narrative Blog, "Watching The Lights Go Out"
A blog by Dr. David Hilfiker: Watching The Lights Go OutA Memoir from Inside Alzheimer's Disease (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Clinical Trials: CRO PRA International Acquired
From Reuters: KKR to buy clinical trials firm PRA International Mon Jun 24, 2013 9:48pm BST Read the article = = = PRA press release: here (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Alzheimer Disease: TTP488 Preparing to Enter Phase III
From WRAL TechWire: TransTech readies Alzheimer's disease treatment for late-stage clinical trialsPosted Jul. 1, 2013 at 12:34 p.m. Read the article (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Alzheimer Disease: Amyvid Debate Over Reimbursement
From Bloomberg: Scientists Back Alzheimer’s Test Amid Doubts Over ValueBy Elizabeth Lopatto - Jun 30, 2013 11:01 PM CT "The U.S. government is set to decide this month whether federal health insurance should cover the cost of a $3,000 test..." Read the news article (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Patient H.M.: The Guardian's Book Review of Corkin's "Permanent Present Tense"
From The Guardian:Permanent Present Tense: The man with no memory, and what he taught the world by Suzanne Corkin – reviewThis fine and moving book reveals as much about the limitations of neuropsychology as about the scope of human memory A review by Jonathan RéeThe Guardian, Thursday 27 June 2013 08.00 BST Read the book review (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Inner Ear Tip Link Regrowth
A news release from the NIH: Researchers discover two-step mechanism of inner ear tip link regrowthTuesday, June 11, 2013, 5 p.m. (EDT) Read the press release (Source: BrainBlog)
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

MOOC: Duke's "Medical Neuroscience" Comes To A Grand End on Coursera
Today is the formal end of a MOOC course on Coursera that was as good an introduction to neuroscience as can be found online, anywhere. Dr. Leonard White at Duke did an incredible job bringing neuroscience alive to thousands of interested students from secondary education on through persons with advanced degrees in, I believe, over 40 countries. A course that forewarned the need to devote 16 to 20 hours a week to attend to lecture material and text (the fifth edition of Purves and colleagues) proceeded with surprising ease (made so by an excellent TA for the course) and sustained interest. Run, don't walk, to enroll should...
Source: BrainBlog - July 2, 2013 Category: Neurologists Source Type: blogs

Dr. Brenda Milner's Interview in The New York Times
Still Charting Memory's DepthsThe New York Times20 May 2013 Read here (Source: BrainBlog)
Source: BrainBlog - May 21, 2013 Category: Neurologists Source Type: blogs

Alzheimer's Disease: Gammagard Fails
From the company press release: Baxter Announces Topline Results of Phase III Study of Immunoglobulin for Alzheimer's Disease DEERFIELD, Ill., May 7, 2013 - Baxter International Inc. (NYSE:BAX) today announced that its Phase III clinical study of immunoglobulin (IG) did not meet its co-primary endpoints of reducing cognitive decline and preserving functional abilities in patients with mild to moderate Alzheimer's disease. The Gammaglobulin Alzheimer's Partnership (GAP) study was conducted by Baxter in collaboration with the Alzheimer's Disease Cooperative Study (ADCS), a clinical trial consortium supported by the United S...
Source: BrainBlog - May 9, 2013 Category: Neurologists Source Type: blogs

MOOC: "Medical Neuroscience" from Duke at Coursera, Week Two
Discussion Forums, including the Instructor (which is good to see). It is an intensive course for a Coursera offering, with a suggested time commitment of 16-to-20 hours per week. Whether this commitment effects un-enrollments over time will be a curious phenomenon. The first week's lectures were a top-notch job of gross neuroanatomy and of cross-sections of interior gross neuroanatomy. Excellent video and presentations. In all, an excellent start to a course that holds a lot of promise for an educational experience! (Source: BrainBlog)
Source: BrainBlog - April 16, 2013 Category: Neurologists Source Type: blogs

MOOC: "Medical Neuroscience" from Duke at Coursera
The new course "Medical Neuroscience" formally opens on Monday at Coursera. Developed and offered by Dr. Leonard E. White at Duke, it looks like an excellent course. The Twitter hashtag for the course is #MedNeuro. (Source: BrainBlog)
Source: BrainBlog - April 6, 2013 Category: Neurologists Source Type: blogs

FDA approves new multiple sclerosis treatment: Tecfidera
27 March 2013 Resd the press release (Source: BrainBlog)
Source: BrainBlog - March 29, 2013 Category: Neurologists Source Type: blogs

TEDEd: Haptics
The Technology of Touchby Dr. Katherine KuchenbeckerTEDEd TalkWatch (Source: BrainBlog)
Source: BrainBlog - March 29, 2013 Category: Neurologists Source Type: blogs

Congratulations, Dr. Anne Treisman, Psychologist
A recipient of the US National Medal of Science. Announced in December, the ceremony was held today. White House release (Source: BrainBlog)
Source: BrainBlog - February 1, 2013 Category: Neurologists Source Type: blogs

Lynda Barry's "The Unthinkable Mind" Class
I am synaptic with jealous for those who are in! :-) Course Description (Source: BrainBlog)
Source: BrainBlog - January 26, 2013 Category: Neurologists Source Type: blogs

Parkinson's Disease: New Biomarker Effort
From the NIH: NIH launches collaborative effort to find biomarkers for Parkinson'sNew online resource will support data sharingNIH News15 January 2013 [snip] "A new initiative aims to accelerate the search for biomarkers — changes in the body that can be used to predict, diagnose or monitor a disease — in Parkinson's disease, in part by improving collaboration among researchers and helping patients get involved in clinical studies. "A lack of biomarkers for Parkinson's has been a major challenge for developing better treatments. The Parkinson’s Disease Biomarkers Program (PDBP) supports efforts ...
Source: BrainBlog - January 20, 2013 Category: Neurologists Source Type: blogs

Happy Birthday, Muhammad Ali!
(Source: BrainBlog)
Source: BrainBlog - January 18, 2013 Category: Neurologists Source Type: blogs

Zulch Prize
Professor Ray Dolan awarded the 2013 Klaus Joachim Zülch PrizeThe Wellcome TrustHolly Story07 Jan 2013 Read article (Source: BrainBlog)
Source: BrainBlog - January 11, 2013 Category: Neurologists Source Type: blogs

OBIT: Dr. Rita Levi-Montalcini
In The New York Times: Obituary (Source: BrainBlog)
Source: BrainBlog - January 1, 2013 Category: Neurologists Source Type: blogs