Could BCG, a 100-year-old Vaccine for Tuberculosis, Protect Against Coronavirus?
This article is republished from The Conversation under a Creative Commons license. Read the original article. The post Could BCG, a 100-year-old Vaccine for Tuberculosis, Protect Against Coronavirus? appeared first on Inter Press Service. (Source: IPS Inter Press Service - Health)
Source: IPS Inter Press Service - Health - May 14, 2020 Category: International Medicine & Public Health Authors: External Source Tags: Global Headlines Health Source Type: news

Combination of chemo and immunotherapy is shown to work against metastatic bladder cancer
(The Mount Sinai Hospital / Mount Sinai School of Medicine) A clinical trial led by Mount Sinai researchers has showed for the first time that combining chemotherapy and immunotherapy can slow down metastatic bladder cancer. The trial also showed that immunotherapy alone may be an option for a subset of patients with metastatic bladder cancer if their tumor expresses a high level of a protein called PD-L1 according to the study, published in The Lancet in May. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 14, 2020 Category: Cancer & Oncology Source Type: news

Scientists recreate DNA damage caused by toxins from smoking
(University of York) Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking.The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor for the disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 28, 2020 Category: Cancer & Oncology Source Type: news

Janssen Announces Submission of Two Applications to U.S. FDA Seeking Approval of SIMPONI ARIA ® (golimumab) for the Treatment of Polyarticular Juvenile Idiopathic Arthritis and Juvenile Psoriatic Arthritis
HORSHAM, PA, April 24, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of two supplemental Biologics License Applications (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of SIMPONI ARIA® (golimumab) for the treatment of polyarticular juvenile idiopathic arthritis (pJIA) and juvenile psoriatic arthritis (jPsA), in patients two years of age and older in combination with methotrexate. If approved for these indications, SIMPONI ARIA would be the first anti-tumor necrosis factor (TNF)-alpha biologic agent administered by intravenous infusion available...
Source: Johnson and Johnson - April 24, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Immunotherapy After Chemo May Slow Metastatic Bladder Cancer Progression Immunotherapy After Chemo May Slow Metastatic Bladder Cancer Progression
In patients with metastatic bladder cancer, progression-free survival was prolonged by switching to pembrolizumab immediately after platinum-based chemotherapy, in a phase-2 trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 16, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

New 'toolbox' for urological cancer detection
(University of Turku) Researchers from Ghent University, Belgium, together with researchers from the University of Turku, Finland, have developed a new method for biomarker discovery of urological cancers. The method enables timely diagnosis and treatment of cancer. Urological cancers include e.g. prostate, bladder and kidney cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 16, 2020 Category: Cancer & Oncology Source Type: news

Immunotherapy treatment after chemotherapy significantly slows metastatic bladder cancer
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Using immunotherapy immediately after chemotherapy treatment in patients with metastatic bladder cancer significantly slowed the progression of the cancer, according to results of a clinical trial led by Mount Sinai researchers published in the Journal of Clinical Oncology in April, 2020. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 9, 2020 Category: Cancer & Oncology Source Type: news

Updated Results for Infigratinib in Metastatic Urothelial Cancer
Researchers reported updated findings of infigratinib in upper tract urothelial carcinoma and urothelial carcinoma of the bladder, supporting the development of phase III studies in this setting. (Source: CancerNetwork)
Source: CancerNetwork - April 2, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

New Florida Legislation Protects Firefighters from Mesothelioma
The Florida Legislature has passed a bill designed to better protect its firefighters from cancer-causing contaminants, including toxic asbestos. By approving the legislation, Florida joined a growing number of states that have passed laws in recent years to help firefighters combat occupational hazards they face every day. The Firefighter Cancer Decontamination Equipment Grant Program in Florida will provide funding for departments to procure supplies, equipment and add additional training that should reduce exposure to hazardous pollutants. It includes all fire departments across the state, from large municipal entities...
Source: Asbestos and Mesothelioma News - March 30, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

E-Cigarette Users Have Carcinogen Biomarkers Linked to Bladder Cancer in Their Urine E-Cigarette Users Have Carcinogen Biomarkers Linked to Bladder Cancer in Their Urine
Biomarkers of carcinogens with a strong link to bladder cancer are present in urine of e-cigarette users, a systematic review suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 26, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Biomarkers of Carcinogens Linked to Bladder Cancer in Urine of E-Cigarette Users
Biomarkers of carcinogens, including several with a strong link to bladder cancer, were found to be present in the urine of e-cigarette users. (Source: CancerNetwork)
Source: CancerNetwork - March 25, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

E-cigarette users had substances linked to bladder cancer in urine, review finds
(UNC Lineberger Comprehensive Cancer Center) In a review published in the journal European Urology Oncology, researchers compiled the results of 22 different studies that analyzed the urine of people who used e-cigarettes or other tobacco products, including cigarettes, to check for evidence of cancer-linked compounds or biomarkers of those compounds. They found six biomarkers or compounds with a strong link to bladder cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 19, 2020 Category: Cancer & Oncology Source Type: news

TERT Promoter Mutations Detectable 10 Years Prior to Bladder Cancer Diagnosis
This study provides the first evidence of the urinary TERT promoter mutations to be used as simple and cost-effective non-invasive biomarkers for the early detection of bladder cancer. (Source: CancerNetwork)
Source: CancerNetwork - February 26, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Simple urine test could improve early detection of bladder cancer – WHO study
A new study conducted by researchers from the United Nations health agency revealed that bladder cancer mutations can be detected in urine up to 10 years before clinically diagnosing the disease. (Source: UN News Centre - Health, Poverty, Food Security)
Source: UN News Centre - Health, Poverty, Food Security - February 20, 2020 Category: International Medicine & Public Health Source Type: news

Simple urine test could help diagnose bladder cancer TEN YEARS before symptoms appear
International researchers used the urine test on 131 people in Iran. Almost half who developed bladder cancer could have been spotted 10 years in advance. (Source: the Mail online | Health)
Source: the Mail online | Health - February 20, 2020 Category: Consumer Health News Source Type: news